26 unknown. 26 Phase 3, 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 26 | Unknown 26 |
| Phase 2 | 5 | Unknown 5 |
Follow Myeloproliferative Disorders: new trials by email Literature Review of Myeloproliferative Disorders trials Research Report on Myeloproliferative Disorders
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Treatment With Olverembatinib in CML-CP Patients Who Failed to at Least Two Previously Administered Second-generation TKIs. olverembatinib - Olverembatinib, Chronic Myeloid Leukemia, Chronic Phase | Phase 3 | Unknown | Shenzhen Second People's Hospital | 40 | 2022-07-01 | 2022-07-29 |
| Nilotinib for First-line Newly Diagnosed CML-CP Patients Nilotinib - Chronic Myeloid Leukemia, Chronic Phase, Nilotinib | Phase 3 | Unknown | Shenzhen Second People's Hospital | 100 | 2019-06-01 | 2022-03-16 |
| KRT-232 Versus Best Available Therapy for the Treatment of Subjects With Myelofibrosis Who Are Relapsed or Refractory to JAK Inhibitor Treatment KRT-232, Best Available Therapy (BAT) - Primary Myelofibrosis (PMF), Post-Polycythemia Vera MF (Post-PV-MF) | Phase 2 / Phase 3 | Unknown | Kartos Therapeutics, Inc. | 385 | 2019-01-15 | 2023-04-28 |
| Evaluation of the Therapeutic Effect of HU Pulse Therapy for CML Patients hydroxyurea, Imatinib - Leukemia, Chronic Myeloid | Phase 3 | Unknown | First Affiliated Hospital of Harbin Medical University | 60 | 2018-05-01 | 2018-05-22 |
| Hydroxyurea Versus Aspirin and Hydroxyurea in Essential Thrombocythemia Aspirin therapy interruption, Usual treatment by aspirin 100 mg/d in the active comparator arm, No interruption of aspirin in the Observational arm - MPN, Essential Thrombocythemia | Phase 3 | Unknown | Assistance Publique - Hôpitaux de Paris | 2250 | 2016-03-10 | 2017-07-26 |
| Malaysia Stop Tyrosine Kinase Inhibitor Trial Peginterferon-α-2a - Leukemia, Chronic Myeloid | Phase 3 | Unknown | Ministry of Health, Malaysia | 118 | 2015-03-01 | 2020-09-14 |
| Thymoglobulin in Unrelated Hematopoietic Progenitor Cell Transplantation Anti-Thymocyte Globulin (Rabbit), Patients will receive a standard preparative regimen (i.e. one that does not contain Thymoglobulin) - Hematologic Malignancies | Phase 3 | Unknown | McMaster University | 198 | 2010-04-01 | 2010-10-08 |
| Evaluation of Plasmatic Levels of Busulfan in Patients Undergoing Hematopoietic Stem Cell Transplantation Analyze the pharmacokinetics of busulfan for transplantation - Acute Leukemia, Chronic Leukemia | Phase 2 / Phase 3 | Unknown | Hospital Israelita Albert Einstein | 100 | 2010-03-01 | 2014-12-03 |
| Unrelated Double Umbilical Cord Blood Units Transplantation Stem cell Transplantation - Leukemia, Myeloid, Acute, Leukemia, Lymphoblastic, Acute | Phase 2 / Phase 3 | Unknown | Tehran University of Medical Sciences | 10 | 2009-11-01 | 2012-06-04 |
| Ketamine Hydrochloride and Best Pain Management in Treating Cancer Patients With Neuropathic Pain ketamine hydrochloride, pharmacogenomic studies, questionnaire administration - Cancer | Phase 3 | Unknown | University of Glasgow | 214 | 2009-04-01 | 2011-05-13 |
| Efficacy of Nilotinib Versus Imatinib in Ph+ CML in Early CP Who Have a Suboptimal Molecular Response to Imatinib Nilotinib, Imatinib - Chronic Myeloid Leukemia | Phase 3 | Unknown | Seoul St. Mary's Hospital | 100 | 2009-01-01 | 2014-01-13 |
| Imatinib Versus Imatinib and Peg-Interferon in Patients With Ph+ CML and Complete Cytogenetic Response After Imatinib Therapy Pegylated Interferon and Imatinib - Leukemia, Myeloid, Philadelphia-Positive | Phase 3 | Unknown | Sheba Medical Center | 90 | 2006-02-01 | 2007-10-10 |
| Vaccine Therapy and GM-CSF in Treating Patients With Acute Myeloid Leukemia in Remission PR1 leukemia peptide vaccine, sargramostim, placebo - Leukemia | Phase 3 | Unknown | The Vaccine Company | 244 | 2005-05-01 | 2014-01-06 |
| Gemtuzumab Ozogamicin in Treating Older Patients With Previously Untreated Acute Myeloid Leukemia gemtuzumab ozogamicin - Leukemia | Phase 2 / Phase 3 | Unknown | European Organisation for Research and Treatment of Cancer - EORTC | 279 | 2004-06-01 | 2012-07-24 |
| Comparing Imatinib Standard Dose With Imatinib High Dose Induction in Pretreated Chronic Myeloid Leukemia (CML) Patients in Chronic Phase Imatinib - Chronic Myeloid Leukemia | Phase 3 | Unknown | Central European Leukemia Study Group | 240 | 2004-01-01 | 2006-06-20 |
| Low-Dose Decitabine Compared With Standard Supportive Care in Treating Older Patients With Myelodysplastic Syndrome decitabine - Leukemia, Myelodysplastic Syndromes | Phase 3 | Unknown | European Organisation for Research and Treatment of Cancer - EORTC | 220 | 2002-05-01 | 2010-04-13 |
| Levofloxacin Compared With Cefepime in Treating Cancer Patients With Fever and Neutropenia cefepime hydrochloride, levofloxacin - Fever, Sweats, and Hot Flashes, Infection | Phase 3 | Unknown | Jonsson Comprehensive Cancer Center | 2001-09-01 | 2013-12-19 | |
| Combination Chemotherapy With or Without Monoclonal Antibody Therapy in Treating Patients With Refractory or Relapsed Acute Myelogenous Leukemia lintuzumab, cytarabine, etoposide - Leukemia | Phase 3 | Unknown | Facet Biotech | 2000-03-01 | 2013-11-06 | |
| Allogeneic Stem Cell Transplantation in CML With Partial T Cell Depletion Stem cell transplantation - Philadelphia Chromosome-positive Chronic Myelocytic Leukemia | Phase 2 / Phase 3 | Unknown | Rambam Health Care Campus | 40 | 1999-12-01 | 2009-08-27 |
| Combination Chemotherapy, Interleukin-2, and Peripheral Stem Cell Transplant in Treating Patients With Acute Myeloid Leukemia aldesleukin, filgrastim, busulfan - Leukemia | Phase 3 | Unknown | European Organisation for Research and Treatment of Cancer - EORTC | 2000 | 1999-09-01 | 2009-12-23 |
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Leukemia (12) · Leukemia, Myelogenous, Chronic, BCR-ABL Positive (11) · Leukemia, Myeloid, Acute (9) · Leukemia, Myeloid, Chronic-Phase (8) · Leukemia, Erythroblastic, Acute (6) · Leukemia, Megakaryoblastic, Acute (6) · Leukemia, Monocytic, Acute (6) · Leukemia, Myelomonocytic, Acute (6) · Congenital Abnormalities (4) · Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative (4) · Leukemia, Myelomonocytic, Chronic (4) · Leukemia, Lymphocytic, Chronic, B-Cell (3) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (3) · Blast Crisis (2)
Bone Marrow Diseases (26) · Hematologic Diseases (26) · Hemic and Lymphatic Diseases (26) · Leukemia, Myeloid (23) · Neoplasms by Histologic Type (23) · Neoplasms (22) · Chronic Disease (17) · Disease Attributes (17) · Pathologic Processes (17) · Pathological Conditions, Signs and Symptoms (17) · Leukemia (11) · Immune System Diseases (5) · Immunoproliferative Disorders (5) · Lymphatic Diseases (5)
Cytarabine (8) · Peripheral Blood Stem Cell Transplantation (6) · Busulfan (5) · Etoposide (5) · Radiotherapy (5) · Cyclophosphamide (4) · Filgrastim (4) · Hydroxyurea (4) · Idarubicin (4) · Imatinib Mesylate (4) · Daunorubicin (3) · Interferon-alpha (3) · Mitoxantrone (3) · Stem Cell Transplantation (2) · nilotinib (2)
European Organisation for Research and Treatment of Cancer - EORTC (4) · Medical Research Council (2) · Shenzhen Second People's Hospital (2) · Assistance Publique - Hôpitaux de Paris (1) · Central European Leukemia Study Group (1) · European Working Group of MDS in Childhood (1) · Facet Biotech (1) · First Affiliated Hospital of Harbin Medical University (1) · German CML Study Group (1) · Hospital Israelita Albert Einstein (1) · III. Medizinische Klinik Mannheim (1) · Jonsson Comprehensive Cancer Center (1) · Kartos Therapeutics, Inc. (1) · McMaster University (1) · Ministry of Health, Malaysia (1)
Germany (7) · United Kingdom (6) · Belgium (4) · Czechia (4) · France (4) · Italy (4) · Netherlands (4) · United States (4) · Austria (3) · Canada (3) · China (3) · Croatia (3) · Israel (3) · Turkey (Türkiye) (3) · Brazil (2)
Ruediger Hehlmann, MD (2) · Alan K. Burnett, MD, FRCP (1) · Amir Ali Hamidieh, MD (1) · Barry J.A. Laird, MD (1) · Charlotte Niemeyer, MD (1) · Craig S. Rosenfeld, MD (1) · Daniel Levitt, MD, PhD (1) · Dong-Wook Kim, MD, PhD (1) · Giovanna Meloni, MD (1) · Giuliana Alimena (1) · Guenther Gastl, MD (1) · Irwin Walker, MD (1) · Izhar Hardan, MD (1) · Jacob M Rowe, MD (1) · Jin Zhou, MD, PhD (1)
PMID 29926156, PMID 30523055, PMID 15010373, PMID 19826132, PMID 20038732, PMID 20145273, PMID 20802024, PMID 22169779, PMID 22511495, PMID 22847303, PMID 24297940, PMID 24986689, PMID 26811524, PMID 29217778, PMID 31089278, PMID 31756535, PMID 31958417, PMID 37341189, PMID 40554414