2 completed. 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 2 | Completed 2 |
Follow Mitochondrial encephalopathy: new trials by email Literature Review of Mitochondrial encephalopathy trials Research Report on Mitochondrial encephalopathy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Phase 2b Study of Zagociguat in Patients With MELAS zagociguat 15mg, zagociguat 30mg, Placebo - Mitochondrial Encephalopathy, Lactic Acidosis and Stroke-Like Episodes (MELAS Syndrome) | Phase 2 | Completed | Tisento Therapeutics | 43 | 2024-09-10 | 2026-10-23 |
| OMT-28 in Patients With Primary Mitochondrial Disease (PMD) (PMD-OPTION) OMT-28 - Primary Mitochondrial Disease | Phase 2 | Completed | Omeicos Therapeutics GmbH | 28 | 2023-05-22 | 2026-01-22 |
Acidosis, Lactic (2) · MELAS Syndrome (2) · Cardiomyopathies (1) · Deafness (1) · MERRF Syndrome (1) · Muscular Diseases (1) · Noninsulin-dependent diabetes mellitus with deafness (1) · Syndrome (1)
Acid-Base Imbalance (2) · Acidosis (2) · Brain Diseases (2) · Brain Diseases, Metabolic (2) · Brain Diseases, Metabolic, Inborn (2) · Cardiovascular Diseases (2) · Central Nervous System Diseases (2) · Cerebral Small Vessel Diseases (2) · Cerebrovascular Disorders (2) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2) · Genetic Diseases, Inborn (2) · Metabolic Diseases (2) · Metabolism, Inborn Errors (2) · Mitochondrial Diseases (2) · Mitochondrial Encephalomyopathies (2)
Omeicos Therapeutics GmbH (1) · Tisento Therapeutics (1)
Germany (2) · Italy (2) · Australia (1) · Canada (1) · Netherlands (1) · United Kingdom (1) · United States (1)