8 completed, 1 unknown, 1 withdrawn. 10 Phase 2, 3 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 10 | Completed 8, Unknown 1, Withdrawn 1 |
| Phase 3 | 3 | Completed 3 |
| Phase 1 | 1 | Completed 1 |
Follow Miscarriage: new trials by email Literature Review of Miscarriage trials Research Report on Miscarriage
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Letrozole and Misoprostol for Early Pregnancy Loss Management Letrozole, Misoprostol - Early Pregnancy Loss, Miscarriage in First Trimester | Phase 2 | Completed | University of Pennsylvania | 19 | 2024-08-22 | 2026-08-10 |
| Intravenous Immunoglobulin and Prednisolone for RPL After ART. Human Intravenous Immunoglobulins, (Privigen (R), CLS Behring), Prednisolone Tablets, Human Albumin Solution - Habitual Abortion, Recurrent Pregnancy Loss | Phase 2 | Completed | Aalborg University Hospital | 80 | 2021-01-28 | 2025-11-24 |
| Comparison of Vaginal Versus Sublingual Misoprostol in the Treatment of First Trimester Missed Miscarriage misoprostol - Miscarriage, Misoprostol | Phase 2 | Completed | Islamabad Medical and Dental College | 120 | 2020-11-02 | 2022-05-24 |
| Letrozole Pretreatment With Misoprostol fInduction of Abortion In First-Trimester Missed Miscarriage Letrozole 2.5mg, Placebo, Misoprostol - Miscarriage, Missed Abortion | Phase 2 | Unknown | Ain Shams Maternity Hospital | 80 | 2018-09-10 | 2018-10-09 |
| Medical Abortion With Single Daily Dose of Misoprostol Misoprostol - Miscarriage | Phase 2 / Phase 3 | Completed | Ain Shams University | 200 | 2018-04-01 | 2019-01-29 |
| Estradiol Pretreatment With Misoprostol in Second Trimester Miscarriage Estradiol, Placebo Oral Tablet, Misoprostol - Miscarriage | Phase 2 / Phase 3 | Completed | Ain Shams University | 200 | 2018-03-21 | 2019-01-29 |
| Hydroxychloroquine (HCQ) for Recurrent Pregnancy Loss Hydroxychloroquine (HCQ), Placebo - Recurrent Pregnancy Loss, Miscarriage | Phase 2 | Withdrawn | University of Utah | 2016-07-01 | 2016-08-12 | |
| Letrozole Pretreatment With Misoprostol for Second-Trimester Medical Abortion Letrozole, Placebo, Misoprostol - Miscarriage | Phase 2 / Phase 3 | Completed | Ain Shams University | 400 | 2015-03-01 | 2017-01-26 |
| Progesterone for the Prevention of Miscarriage and Preterm Birth in Women With First Trimester Bleeding: PREEMPT Trial Progesterone, Placebo - Miscarriage, Preterm Birth | Phase 2 | Completed | Sir Mortimer B. Davis - Jewish General Hospital | 850 | 2014-12-01 | 2021-08-23 |
| Couples Miscarriage Healing Project:Randomized Trial Nurse Caring, Self Caring, Combined Caring - Miscarriage, Grief | Phase 1 / Phase 2 | Completed | University of Washington | 682 | 2001-09-01 | 2008-02-18 |
Abortion, Spontaneous (10) · Abortion, Habitual (1) · Abortion, Missed (1) · Premature Birth (1)
Female Urogenital Diseases and Pregnancy Complications (10) · Pregnancy Complications (10) · Urogenital Diseases (10) · Obstetric Labor Complications (1) · Obstetric Labor, Premature (1)
Misoprostol (6) · Letrozole (3) · Alprostadil (1) · Estradiol (1) · Hydroxychloroquine (1) · Immunoglobulins, Intravenous (1) · Prednisolone (1) · Progesterone (1)
Ain Shams University (3) · Aalborg University Hospital (1) · Ain Shams Maternity Hospital (1) · Islamabad Medical and Dental College (1) · Sir Mortimer B. Davis - Jewish General Hospital (1) · University of Pennsylvania (1) · University of Utah (1) · University of Washington (1)
Egypt (4) · United States (3) · Canada (1) · Denmark (1) · Pakistan (1)
Ahmed Swidan, M.B.B.ch (1) · Gasser El-Bishry, FRCOG (1) · Haim Abenhaim, MD, MPH (1) · Ihab Serag-ElDin, MD (1) · Kristen M Swanson, RN, PhD (1) · Mohamed S. Sweed, MD (1) · Mostafa Gomaa, MD (1) · Ole B Christiansen (1) · Robert Silver, MD (1)
R01NR005343 (1)