3 completed, 1 active not recruiting, 1 recruiting, 1 terminated. 4 Phase 1, 2 Phase 2, 1 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Active not recruiting 1, Completed 1, Recruiting 1, Terminated 1 |
| Phase 2 | 2 | Recruiting 1, Withdrawn 1 |
| Not applicable | 1 | Completed 1 |
Follow Metastatic Malignant Neoplasm in the Central Nervous System: new trials by email Literature Review of Metastatic Malignant Neoplasm in the Central Nervous System trials Research Report on Metastatic Malignant Neoplasm in the Central Nervous System
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Patient and Caregiver Priorities in Neuro-oncology Care Non-Interventional Study - Malignant Central Nervous System Neoplasm, Metastatic Malignant Neoplasm in the Central Nervous System | Completed | Mayo Clinic | 33 | 2024-04-24 | 2026-04-01 | |
| E6201 and Dabrafenib for the Treatment of Central Nervous System Metastases From BRAF V600 Mutated Metastatic Melanoma Dabrafenib, MEK-1/MEKK-1 Inhibitor E6201, Biospecimen Collection - Clinical Stage IV Cutaneous Melanoma AJCC v8, Metastatic Malignant Neoplasm in the Brain | Phase 1 | Terminated | Mayo Clinic | 13 | 2022-10-20 | 2025-08-19 |
| CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma Biospecimen Collection, Bone Marrow Aspirate, Bone Marrow Biopsy - Diffuse Midline Glioma, H3 K27-Altered, Metastatic Malignant Neoplasm in the Central Nervous System | Phase 1 / Phase 2 | Recruiting | Children's Oncology Group | 63 | 2022-01-28 | 2026-09-11 |
| An Investigational Scan (7T MRI) for the Imaging of Central Nervous System Tumors 7 Tesla Magnetic Resonance Imaging, Questionnaire Administration - Central Nervous System Neoplasm, Glioma | Not applicable | Completed | M.D. Anderson Cancer Center | 50 | 2020-09-04 | 2025-01-08 |
| WSD0922-FU for Treatment of Glioblastoma, Anaplastic Astrocytoma, or Non-small Cell Lung Cancer With Central Nervous System Metastases Biospecimen Collection - blood samples, Biospecimen Collection - CSF samples, Computed Tomography - Anaplastic Astrocytoma, IDH-Wildtype, Glioblastoma, IDH-Wildtype | Phase 1 | Active not recruiting | Mayo Clinic | 56 | 2019-12-20 | 2026-08-10 |
| Brigatinib in Treating Patients With ALK and ROS1 Gene Alterations and Locally Advanced or Metastatic Solid Cancers Brigatinib, Laboratory Biomarker Analysis, Quality-of-Life Assessment - Advanced Malignant Neoplasm, ALK Fusion Protein Expression | Phase 2 | Withdrawn | Sameek Roychowdhury | 2019-03-20 | 2022-02-18 | |
| Hyperpolarized Carbon C 13 Pyruvate Magnetic Resonance Spectroscopic Imaging in Detecting Lactate and Bicarbonate in Participants With Central Nervous System Tumors Gadolinium, Hyperpolarized Carbon C 13 Pyruvate, Magnetic Resonance Imaging - Malignant Central Nervous System Neoplasm, Metastatic Malignant Neoplasm in the Central Nervous System | Phase 1 | Completed | Daniel M. Spielman | 9 | 2018-11-06 | 2023-12-21 |
Central Nervous System Neoplasms (3) · Brain Neoplasms (2) · Neoplasm Metastasis (2) · Astrocytoma (1) · Carcinoma, Non-Small-Cell Lung (1) · Diffuse Intrinsic Pontine Glioma (1) · Glioblastoma (1) · Glioma (1) · Lung Neoplasms (1) · Lymphoma (1) · Melanoma (1)
Neoplasms (7) · Neoplasms by Site (7) · Nervous System Diseases (6) · Nervous System Neoplasms (6) · Neoplasms by Histologic Type (4) · Neoplasms, Germ Cell and Embryonal (4) · Neoplasms, Nerve Tissue (4) · Neuroectodermal Tumors (4) · Brain Diseases (3) · Central Nervous System Diseases (3) · Central Nervous System Neoplasms (3) · Neoplasms, Glandular and Epithelial (3) · Neoplasms, Neuroepithelial (3) · Glioma (2) · Neoplastic Processes (2)
Magnetic Resonance Spectroscopy (3) · Specimen Handling (3) · 14-(ethylamino)-8,9,16-trihydroxy-3,4-dimethyl-3,4,9,19-tetrahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione (1) · Biopsy (1) · CBLC137 (1) · Fluid Therapy (1) · Gadolinium (1) · brigatinib (1) · dabrafenib (1)
Mayo Clinic (3) · Children's Oncology Group (1) · Daniel M. Spielman (1) · M.D. Anderson Cancer Center (1) · Sameek Roychowdhury (1)
United States (7) · Australia (1)
David S Ziegler (1) · Hani M. Babiker, MD (1) · Lawrence Recht (1) · Max Wintermark (1) · Sameek Roychowdhury, MD (1) · Sani H. Kizilbash, M.D., M.P.H. (1) · Ugur T. Sener, MD (1)
P30CA016058 (1), R01CA245097 (1), UM1CA228823 (1)