3 active not recruiting, 1 completed. 4 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Active not recruiting 3, Completed 1 |
| Phase 1 | 1 | Active not recruiting 1 |
Follow Metastatic Head and Neck Carcinoma: new trials by email Literature Review of Metastatic Head and Neck Carcinoma trials Research Report on Metastatic Head and Neck Carcinoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLC ONC-392, Pembrolizumab, Docetaxel - Non Small Cell Lung Cancer, Advanced Solid Tumor | Phase 1 / Phase 2 | Active not recruiting | OncoC4, Inc. | 733 | 2020-09-16 | 2026-09-14 |
| Pembrolizumab & Cabozantinib in Patients With Head and Neck Squamous Cell Cancer Cabozantinib, Pembrolizumab - Metastatic Head and Neck Carcinoma, Paranasal Sinus Squamous Cell Carcinoma | Phase 2 | Active not recruiting | Emory University | 36 | 2018-09-18 | 2026-01-23 |
| Recombinant EphB4-HSA Fusion Protein and Pembrolizumab, MK-3475 Laboratory Biomarker Analysis, Pembrolizumab, Recombinant EphB4-HSA Fusion Protein - ALK Gene Mutation, BRAF Gene Mutation | Phase 2 | Completed | University of Southern California | 42 | 2017-03-10 | 2025-10-22 |
| Thermal Ablation and Spine Stereotactic Radiosurgery in Treating Patients With Spine Metastases at Risk for Compressing the Spinal Cord Computed Tomography, Quality-of-Life Assessment, Questionnaire Administration - Malignant Digestive System Neoplasm, Metastatic Head and Neck Carcinoma | Phase 2 | Active not recruiting | M.D. Anderson Cancer Center | 60 | 2016-08-29 | 2026-10-07 |
Carcinoma, Non-Small-Cell Lung (2) · Carcinoma, Renal Cell (2) · Melanoma (2) · Sarcoma (2) · Squamous Cell Carcinoma of Head and Neck (2) · Breast Neoplasms (1) · Carcinoma, Adenoid Cystic (1) · Carcinoma, Transitional Cell (1) · Colorectal Neoplasms (1) · Esophageal Neoplasms (1) · Gastrointestinal Neoplasms (1) · Neoplasms, Unknown Primary (1) · Ovarian Neoplasms (1) · Pancreatic Neoplasms (1) · Prostatic Neoplasms (1)
Carcinoma (4) · Head and Neck Neoplasms (4) · Neoplasms (4) · Neoplasms by Histologic Type (4) · Neoplasms by Site (4) · Neoplasms, Glandular and Epithelial (4) · Adenocarcinoma (2) · Bronchial Neoplasms (2) · Carcinoma, Bronchogenic (2) · Carcinoma, Squamous Cell (2) · Digestive System Diseases (2) · Digestive System Neoplasms (2) · Endocrine Gland Neoplasms (2) · Endocrine System Diseases (2) · Female Urogenital Diseases (2)
pembrolizumab (3) · Docetaxel (1) · Radiosurgery (1) · Transurethral Resection of Prostate (1) · cabozantinib (1)
Emory University (1) · M.D. Anderson Cancer Center (1) · OncoC4, Inc. (1) · University of Southern California (1)
United States (4) · Australia (1)
Jing Li (1) · Jorge Nieva, MD (1) · Nabil F. Saba, MD (1) · Tianhong Li, MD (1)
P30CA014089 (1), P30CA016672 (1), P30CA138292 (1), R44CA250824 (1)