5 unknown, 3 completed, 1 not yet recruiting, 1 suspended. 10 Phase 3, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 10 | Unknown 5, Completed 3, Not yet recruiting 1, Suspended 1 |
| Phase 2 | 4 | Unknown 2, Not yet recruiting 1, Suspended 1 |
Follow Melasma: new trials by email Literature Review of Melasma trials Research Report on Melasma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of the Efficacy of Oral Tranexamic Acid and Glutathione-assisted Microneedling in Treatment of Melasma microneedling, Oral tranexamic acid, Glutathione - Melasma | Phase 2 / Phase 3 | Not yet recruiting | Assiut University | 42 | 2026-02-01 | 2026-03-04 |
| The Effectiveness of 3% Topical Tranexamic Acid Compared to 4% Topical Hydroquinone as Therapy of Melasma 3 % Topical Tranexamic Acid, 4% Topical Hidroquinone - Melasma | Phase 3 | Unknown | Universitas Indonesia | 20 | 2023-06-01 | 2023-09-21 |
| Evaluation of Laser and Tranexamic Acid in Treatment of Melasma Tranexamic acid - Melasma | Phase 2 / Phase 3 | Unknown | Assiut University | 40 | 2020-12-01 | 2020-10-22 |
| Cysteamine Compared to Hydroquinone in Melasma 5% cysteamine cream, hydroquinone cream group - Melasma | Phase 3 | Completed | China Medical University Hospital | 28 | 2019-11-28 | 2023-08-07 |
| Oral and Topical Tranexamic Acid for the Treatment of Melasma Oral Tranexamic Acid, 5% topical tranexamic acid, 4% hydroquinone - Melasma, Chloasma | Phase 3 | Unknown | Centro Dermatológico Dr. Ladislao de la Pascua | 120 | 2018-08-01 | 2018-07-16 |
| Platelet Rich Plasma in Treatment of Melasma Platelet rich plasma - Melasma, Platelet Rich Plasma | Phase 3 | Unknown | Assiut University | 26 | 2017-11-01 | 2018-06-27 |
| Oral Tranexamic Acid and Topical Hydroquinone in the Treatment of Melasma Tranexamic Acid Oral Product, Hydroquinone 4% Cream, Sunscreen - Melasma | Phase 3 | Completed | Fakultas Kedokteran Universitas Indonesia | 50 | 2016-03-16 | 2018-11-26 |
| Melanil in the Treatment of Melasma Melanil facial cream, Hydroquinone 2% cream - Melasma | Phase 3 | Completed | Catalysis SL | 150 | 2009-10-01 | 2012-05-04 |
| Azelaic Acid Iontophoresis Versus Topical Azelaic Acid Cream in the Treatment of Melasma Iontophoresis, Azelaic acid cream - Melasma | Phase 2 / Phase 3 | Unknown | Medical University of Vienna | 70 | 2009-01-01 | 2010-07-15 |
| Efficiency And Safety Of Association Arbutin, Triamcinolone And Tretinoin In Treatment Of Melasma arbutin, tretinoin, triamcinolone, Triluma - Melasma | Phase 2 / Phase 3 | Suspended | Azidus Brasil | 110 | 2008-07-01 | 2022-11-03 |
Melanosis (10)
Hyperpigmentation (10) · Pigmentation Disorders (10) · Skin Diseases (10) · Skin and Connective Tissue Diseases (10)
Tranexamic Acid (4) · hydroquinone (3) · Percutaneous Collagen Induction (2) · Arbutin (1) · Glutathione (1) · Iontophoresis (1) · Lasers (1) · Sun Protection Factor (1) · Sunscreening Agents (1) · Tretinoin (1) · Triamcinolone (1)
Assiut University (3) · Azidus Brasil (1) · Catalysis SL (1) · Centro Dermatológico Dr. Ladislao de la Pascua (1) · China Medical University Hospital (1) · Fakultas Kedokteran Universitas Indonesia (1) · Medical University of Vienna (1) · Universitas Indonesia (1)
Austria (1) · Brazil (1) · Cuba (1) · Egypt (1) · Indonesia (1) · Mexico (1) · Taiwan (1)
Alaa H Ghazally, MD (1) · Alfredo Abreu Daniel, PhD (1) · JB Schmidt, MD (1) · Nevi Yasnova, MD (1) · Oliver Schanab, MD (1)