7 completed. 7 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 7 | Completed 7 |
Follow Melasma: new trials by email Literature Review of Melasma trials Research Report on Melasma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy of Eflornithine Hydrochloride Cream in the Treatment of Melasma: A Randomized, Double-blinded, Split-face Controlled Study Eflornithine hydrochloride cream, Hydroquinone cream - Melasma | Phase 2 | Completed | National Skin Centre | 20 | 2023-06-06 | 2025-05-05 |
| To Evaluate the Effectiveness of Topical Eflornithine 9.58% + Hydroquinone 4% + Fluocinolone 0.01% as Compared to Topical Tretinoin 0.05% + Hydroquinone 4% + Fluocinolone 0.01% for the Treatment of Melasma Eflornithine 9.58% + Hydroquinone 4% + Fluocinolone 0.01% cream, Tretinoin 0.05% + hydroquinone 4% + fluocinolone 0.01% cream - Melasma, Melasma (Facial Melasma) | Phase 2 | Completed | National Skin Centre | 30 | 2023-06-06 | 2026-11-05 |
| Comparison of 30% Metformin and 2% Nicotinamide Lotion With Kligman Formula in the Treatment of Melasma Metformin and Nicotinamide vs Kligman Formula - Melasma | Phase 2 | Completed | Ishtiaq Ahmed | 88 | 2022-02-01 | 2023-05-23 |
| Comparison of Topical Silymarin With Hydroquinone in the Treatment of Melasma Hydroquinone 4% Cream, silymarin 0.7% cream - Melasma | Phase 2 | Completed | Islamabad Medical and Dental College | 92 | 2019-07-15 | 2020-02-12 |
| Efficacy of Platelet-rich Plasma in Treatment of Melasma Platelet-Rich Plasma - Melasma | Phase 2 | Completed | Instituto Mexicano del Seguro Social | 20 | 2017-05-01 | 2019-01-28 |
| A Comparative Study for Efficacy and Safety Between 4% Hydroquinone Cream With or Without Fractional Picosecond 1,064 nm Laser for the Treatment of Dermal or Mixed Type Melasma Fractional Picosecond 1,064 nm laser, 4% hydroquinone cream - Picoseconds Laser, Melasma | Phase 2 | Completed | Mae Fah Luang University Hospital | 30 | 2016-06-01 | 2017-02-09 |
| Topical Composition Therapy (2013-MCN-333) for the Treatment of Melasma Illuminate Cream - Melasma | Phase 2 | Completed | Mayo Clinic | 19 | 2016-05-15 | 2017-10-20 |
Melanosis (7)
Hyperpigmentation (7) · Pigmentation Disorders (7) · Skin Diseases (7) · Skin and Connective Tissue Diseases (7)
hydroquinone (2) · Eflornithine (1) · Lasers (1) · Metformin (1) · Silymarin (1) · Tretinoin (1) · fluocinolone (1)
National Skin Centre (2) · Instituto Mexicano del Seguro Social (1) · Ishtiaq Ahmed (1) · Islamabad Medical and Dental College (1) · Mae Fah Luang University Hospital (1) · Mayo Clinic (1)
Pakistan (2) · Singapore (2) · Mexico (1) · United States (1)
Clotilde Fuentes, pHD (1) · Ishtiaq Ahmed, MBBS (1) · Jason C Sluzevich, M.D. (1) · Sumaira Abdullah, MBBS, MCPS, MD (1)
2019 (1)