1 active not recruiting, 1 recruiting. 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 2 | Active not recruiting 1, Recruiting 1 |
Follow Malignancies: new trials by email Literature Review of Malignancies trials Research Report on Malignancies
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase 2, Open-label, Single-arm Study on the Use of Metformin as Adjunctive Therapy in High-grade Glioma Metformin - Glioblastoma, IDH-wildtype, Metformin | Phase 2 | Recruiting | University of Milano Bicocca | 25 | 2024-02-12 | 2025-07-25 |
| 9-ING-41 in Patients With Advanced Cancers 9-ING-41, Gemcitabine - 21 day cycle, Doxorubicin. - Cancer, Pancreatic Cancer | Phase 2 | Active not recruiting | Actuate Therapeutics Inc. | 350 | 2019-01-04 | 2026-04-03 |
Glioma (2) · Neoplasms (2) · Bone Neoplasms (1) · Breast Neoplasms (1) · Colorectal Neoplasms (1) · Glioblastoma (1) · Hereditary Sensory and Autonomic Neuropathies (1) · Kidney Neoplasms (1) · Leukemia-Lymphoma, Adult T-Cell (1) · Lung Neoplasms (1) · Lymphoma, Non-Hodgkin (1) · Neoplasm Metastasis (1) · Pancreatic Neoplasms (1) · Sarcoma (1)
Neoplasms by Histologic Type (2) · Neoplasms, Germ Cell and Embryonal (2) · Neoplasms, Glandular and Epithelial (2) · Neoplasms, Nerve Tissue (2) · Neoplasms, Neuroepithelial (2) · Neuroectodermal Tumors (2) · Astrocytoma (1) · Bone Diseases (1) · Breast Diseases (1) · Colonic Diseases (1) · Congenital Abnormalities (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Digestive System Diseases (1) · Digestive System Neoplasms (1) · Endocrine Gland Neoplasms (1)
3-(5-fluorobenzofuran-3-yl)-4-(5-methyl-5H-(1,3)dioxolo(4,5-f)indol-7-yl)-pyrrole-2,5-dione (1) · Albumin-Bound Paclitaxel (1) · Carboplatin (1) · Doxorubicin (1) · Gemcitabine (1) · Irinotecan (1) · Lomustine (1) · Metformin (1) · Paclitaxel (1) · Taxes (1) · liposomal doxorubicin (1)
Actuate Therapeutics Inc. (1) · University of Milano Bicocca (1)
Belgium (1) · Canada (1) · France (1) · Italy (1) · Netherlands (1) · Portugal (1) · Spain (1) · United States (1)
PMID 24327518, PMID 27424289, PMID 28053024, PMID 28672195, PMID 29383130, PMID 29846250, PMID 30405781, PMID 30975030, PMID 31101621, PMID 31401903, PMID 31533931, PMID 31831767, PMID 31882719, PMID 31894292, PMID 35815408, PMID 41981308