34 unknown, 32 recruiting, 25 completed, 12 not yet recruiting. 42 Phase 2, 19 Phase 1, 15 Not applicable, 10 Phase 3, 3 Early Phase 1.
Follow Lung Adenocarcinoma: new trials by email Literature Review of Lung Adenocarcinoma trials Research Report on Lung Adenocarcinoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Firmonertinib Plus Chemotherapy for Unresectable EGFR PACC-Mutant Stage III Lung Cancer: A Phase II Study Firmonertinib, Platinum-based chemotherapy - Lung Adenocarcinoma, Stage III Lung Cancer | Phase 2 | Not yet recruiting | Hunan Province Tumor Hospital | 27 | 2026-11-01 | 2026-10-16 |
| Phase 1 Study of NW-301V TCR-T Cells in Advanced Solid Tumors With KRAS G12V Mutation Fludarabine, Cyclophosphamide, NW-301V - Advanced Solid Cancer, Pancreatic Ductal Adenocarcinoma (PDAC) | Phase 1 | Not yet recruiting | Neowise Biotechnology | 66 | 2026-10-01 | 2026-10-15 |
| SL-28 for Advanced Solid Tumours SL-28 - Head & Neck Cancer, Pancreas Carcinoma | Phase 1 / Phase 2 | Recruiting | Second Life Therapeutics | 60 | 2026-08-14 | 2026-09-15 |
| Inhaled Cromolyn Sodium in Patients With Locally Advanced Lung Cancer Cromolyn Sodium - Locally Advanced Non-Small Cell Lung Cancer, Lung Adenocarcinoma | Phase 1 | Not yet recruiting | Carcinex Inc | 10 | 2026-08-01 | 2026-07-01 |
| DBC-664 in Adult Patients With Solid Tumors DBC-664 - Malignant Germ Cell Tumor, Lung Adenocarcinoma | Phase 1 | Recruiting | Duboce Biopharmaceuticals, Inc. | 210 | 2026-07-17 | 2026-09-29 |
| CLINICAL STUDY TO IDENTIFY BIOMARKERS FOR TUMOR SPREAD THROUGH AIR SPACES STATUS Lung Adenocarcinoma | Not yet recruiting | Universidade Nova de Lisboa | 140 | 2026-06-01 | 2026-06-05 | |
| Peripheral Blood ETASTs for Predicting Efficacy of Chemoimmunotherapy in NSCLC Circulating Tumor-Specific T Cell Nanodetection Technology (CTT-NanoDT) - Non-Small Cell Lung Cancer, Lung Adenocarcinoma | Not yet recruiting | Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | 80 | 2026-04-01 | 2026-02-06 | |
| Bevacizumab Plus FSRT Versus Hippocampus-Avoidant WBRT in Lung Adenocarcinoma With Extensive Brain Metastases FSRT, HA-WBRT-SIB, Bevacizumab - Lung Adenocarcinoma, Brain Metastases | Phase 3 | Recruiting | Sun Yat-sen University | 220 | 2026-03-20 | 2026-04-06 |
| Vortioxetine for Cognitive Function in ALK-positive NSCLC Treated With Lorlatinib Advanced ALK/ROS1-positive NSCLC, Carcinoma, Non-Small-Cell Lung (NSCLC) | Recruiting | Centro de Tratamiento e Investigación sobre Cáncer, Luis Carlos Sarmiento Angulo | 24 | 2026-03-10 | 2026-06-08 | |
| Engagement of Veterans With Lung Cancer Lay Health Worker (LHW) Planning, Usual Care Group - Lung Cancer (NSCLC), Lung Adenocarcinoma | Not applicable | Recruiting | Palo Alto Veterans Institute for Research | 194 | 2026-02-27 | 2026-03-03 |
| Partial Tumor Irradiation and Immunotherapy for Unresectable Lung Cancer Partial Tumor Irradiation - Lung Adenocarcinoma, Bulky Tumors | Not applicable | Recruiting | Karl Landsteiner University of Health Sciences | 10 | 2026-02-02 | 2026-02-20 |
| PHOENIX: QL1706 Plus Chemotherapy and Bevacizumab in AGA-Resistant, PD-L1 ≥50% Non-Squamous NSCLC QL1706 (bispecific antibody targeting PD-1 and CLTA-4) - Lung Adenocarcinoma | Phase 2 | Not yet recruiting | Guangdong Association of Clinical Trials | 61 | 2026-01-31 | 2026-02-17 |
| ADH1B and ALDH Gene Variants and Lung Cancer Risk Condition/Disease, Lung Cancer (Diagnosis) | Not yet recruiting | Kaohsiung Medical University | 100000 | 2026-01-01 | 2025-12-09 | |
| Evaluation of Different Sizes of Left-Sided Double-Lumen Tubes for Thoracic Surgery in a Tertiary Level Teaching Hospital Intubation of patients undergoing thoracic surgery with left sided double lumen tube - Lung Adenocarcinoma, Lung Abscess | Not applicable | Not yet recruiting | Tribhuvan University, Nepal | 60 | 2026-01-01 | 2026-01-28 |
| Testing the Safety of Dapagliflozin Prior to Surgery for the Treatment of Patients With Stage IA Lung Adenocarcinoma Biospecimen Collection, Computed Tomography Assisted Biopsy, Dapagliflozin Propanediol - Lung Adenocarcinoma, Stage IA1 Lung Cancer American Joint Committee on Cancer (AJCC) v8 | Early Phase 1 | Recruiting | Jonsson Comprehensive Cancer Center | 48 | 2025-12-02 | 2026-02-19 |
| Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors Biopsy, Biospecimen Collection, Computed Tomography - Metastatic Malignant Solid Neoplasm, Metastatic Melanoma | Phase 1 | Recruiting | Anusha Kalbasi | 18 | 2025-10-07 | 2026-03-17 |
| Segmentectomy vs Lobectomy for 2 - 3cm IASLC Grade 1-2 Lung Adenocarcinoma: A Multi-center RCT Pulmonary segmentectomy - Lung Adenocarcinoma | Phase 3 | Not yet recruiting | Shanghai Pulmonary Hospital, Shanghai, China | 587 | 2025-10-01 | 2025-09-12 |
| Low-glucose/High-fat Intake Dietary Regimen as a Tool for Empowering Diagnostic Accuracy of 2-[18F]FDG PET/CT in Lepidic-predominant Growth Lung Adenocarcinoma Ketogenic diet, 2-[18F]FDG PET/CT - Lepidic-Predominant Lung Adenocarcinoma, Lung Adenocarcinoma | Not applicable | Recruiting | Fondazione del Piemonte per l'Oncologia | 30 | 2025-07-03 | 2026-03-20 |
| Pleural Effusion Biomarkers in Lung Adenocarcinoma Patients biomarkers - Biomarkers, Lung Adenocarcinoma | Recruiting | Fu Jen Catholic University | 100 | 2025-06-10 | 2026-03-05 | |
| Orlistat Overcoming Third-generation EGFR-TKI Resistance Orlistat 120 mg - Lung Adenocarcinoma, Osimertinib | Phase 2 | Not yet recruiting | Ping Peng | 36 | 2025-02-16 | 2025-02-12 |
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Adenocarcinoma of Lung (124) · Lung Neoplasms (30) · Carcinoma, Non-Small-Cell Lung (27) · Pancreatic Neoplasms (8) · Colorectal Neoplasms (7) · Ovarian Neoplasms (7) · Adenocarcinoma, Bronchiolo-Alveolar (6) · Adenocarcinoma (4) · Breast Neoplasms (4) · Melanoma (4) · Small Cell Lung Carcinoma (4) · Endometrial Neoplasms (3) · Neoplasm Metastasis (3) · Triple Negative Breast Neoplasms (3) · Adrenocortical Carcinoma (2)
Neoplasms by Histologic Type (124) · Neoplasms by Site (124) · Neoplasms, Glandular and Epithelial (124) · Respiratory Tract Neoplasms (124) · Thoracic Neoplasms (124) · Carcinoma (122) · Neoplasms (122) · Adenocarcinoma (120) · Lung Neoplasms (94) · Respiratory Tract Diseases (48) · Lung Diseases (45) · Bronchial Neoplasms (28) · Carcinoma, Bronchogenic (28) · Endocrine Gland Neoplasms (14) · Endocrine System Diseases (14)
Pemetrexed (14) · Bevacizumab (12) · Carboplatin (11) · Cisplatin (8) · Erlotinib Hydrochloride (7) · pembrolizumab (6) · Gefitinib (5) · Mastectomy, Segmental (5) · Paclitaxel (5) · Platinum (5) · Radiotherapy (5) · Magnetic Resonance Spectroscopy (4) · Radiation (4) · Biopsy (3) · Specimen Handling (3)
Fudan University (9) · National Cancer Institute (NCI) (8) · Shanghai Pulmonary Hospital, Shanghai, China (6) · Cancer Institute and Hospital, Chinese Academy of Medical Sciences (3) · Henan Cancer Hospital (3) · Hunan Province Tumor Hospital (3) · Sun Yat-sen University (3) · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (3) · China Medical University Hospital (2) · First People's Hospital of Hangzhou (2) · Fujian Cancer Hospital (2) · Ikena Oncology (2) · Jonsson Comprehensive Cancer Center (2) · Mayo Clinic (2) · Memorial Sloan Kettering Cancer Center (2)
China (44) · United States (35) · Canada (4) · France (4) · Israel (4) · Taiwan (4) · Australia (3) · Italy (3) · South Korea (3) · Spain (3) · Turkey (Türkiye) (2) · Austria (1) · Colombia (1) · Germany (1) · Greece (1)
Haiquan Chen, M.D. (3) · Hui Liu, Professor (2) · Len Reyno, MD (2) · Marc Chamberlain, MD (2) · Adam Crystal, MD, PhD (1) · Afshin Dowlati (1) · Aiqin Gu, MD (1) · Allison Betof Warner, MD, PhD (1) · Ana Gleisner, MD (1) · Antoinette J Wozniak (1) · Antoni Ribas, MD, PhD (1) · Azam Ghafoor, M.D. (1) · Ba Yi (1) · Catherine Shannon (1)
PMID 15254054, PMID 16757720, PMID 16856022, PMID 19801201, PMID 21681372, PMID 22581306, PMID 23814264, PMID 25349290, PMID 26013109, PMID 26866579, PMID 27458945, PMID 28073680, PMID 28665143, PMID 28950351, PMID 29420112, PMID 29487223, PMID 29562855, PMID 30017884, PMID 30395902, PMID 30825389, PMID 31569068, PMID 31806360, PMID 32058845, PMID 32347302, PMID 32483558, PMID 32805489, PMID 33255425, PMID 34283064, PMID 34323922, PMID 34629425, PMID 34686340, PMID 35130505, PMID 35254001, PMID 35509435, PMID 35529792, PMID 35604701, PMID 35613998, PMID 36123064, PMID 36200668, PMID 36827396, PMID 37238744, PMID 37286305, PMID 37507393, PMID 37594667, PMID 38152395, PMID 38372949, PMID 38781043, PMID 38809056, PMID 38960464, PMID 39325429
U10CA180888 (3), N01CM62209 (2), U10CA032102 (2), U10CA180821 (2), 2016 (1), N01CM00038 (1), N01CM00071 (1), P30CA013330 (1), P30CA033572 (1), P30CA043703 (1), P50CA058184 (1), R21CA153000 (1), U10CA021115 (1), U10CA031946 (1), U10CA180820 (1)