3 completed, 1 terminated, 1 unknown. 5 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Completed 3, Terminated 1, Unknown 1 |
| Phase 3 | 1 | Unknown 1 |
Follow Loiasis: new trials by email Literature Review of Loiasis trials Research Report on Loiasis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A 3- to 5-day Clinical Trial of Levamisole in Loiasis Infected Subjects Levamisole 3 days, Levamisole 5 days, Placebo - Loiasis | Phase 2 / Phase 3 | Unknown | Programme National de Lutte contre l'Onchocercose, Republic of the Congo | 99 | 2024-06-21 | 2024-09-20 |
| Clinical Trial Evaluating the Safety and Efficacy of Moxidectin 2 mg Ivermectin-controlled in Loa Loa Microfilaremic Patients Moxidectin 2 MG Oral Tablet, Ivermectin 3Mg Tab, Placebo oral tablet - Onchocerciasis, Ocular, Loiasis | Phase 2 | Completed | Center for Research on Filariasis and Other Tropical Diseases, Cameroon | 72 | 2022-04-07 | 2025-02-24 |
| Clinical Trial Evaluating the Safety and Efficacy of Levamisole in Loa Loa Microfilaremic Patients LEV 1 mg/kg, LEV 1,5 mg/kg, LEV 2,5 mg/kg - Onchocerciasis, Ocular, Loiasis | Phase 2 | Completed | Programme National de Lutte contre l'Onchocercose, Republic of the Congo | 255 | 2021-01-16 | 2021-09-20 |
| Efficacy and Microfilaricidal Kinetics of Imatinib for the Treatment of Loa Loa Imatinib Mesylate, Placebo - Loiasis | Phase 2 | Terminated | National Institute of Allergy and Infectious Diseases (NIAID) | 20 | 2019-09-16 | 2022-06-07 |
| Reslizumab to Prevent Post-treatment Eosinophilia in Loiasis Reslizumab, Diethylcarbamazine, Placebo - Loiasis | Phase 2 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 31 | 2010-04-01 | 2022-01-27 |
Filariasis (2) · Onchocerciasis, Ocular (2) · Onchocerciasis (1)
Helminthiasis (5) · Infections (5) · Nematode Infections (5) · Parasitic Diseases (5) · Secernentea Infections (5) · Spirurida Infections (5) · Filariasis (3) · Eye Diseases (2) · Eye Infections (2) · Eye Infections, Parasitic (2) · Onchocerciasis (2) · Vector Borne Diseases (2) · Skin Diseases (1) · Skin Diseases, Infectious (1) · Skin Diseases, Parasitic (1)
Levamisole (2) · Diethylcarbamazine (1) · Imatinib Mesylate (1) · Ivermectin (1) · Tablets (1) · moxidectin (1) · reslizumab (1)
National Institute of Allergy and Infectious Diseases (NIAID) (2) · Programme National de Lutte contre l'Onchocercose, Republic of the Congo (2) · Center for Research on Filariasis and Other Tropical Diseases, Cameroon (1)
Cameroon (2) · Republic of the Congo (2) · United States (1)
Amy D Klion, M.D. (1) · Elise M O'Connell, M.D. (1)