5 recruiting, 3 unknown, 1 active not recruiting, 1 completed. 5 Phase 2, 2 Phase 1, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Recruiting 2, Active not recruiting 1, Completed 1, Unknown 1 |
| Phase 1 | 2 | Completed 1, Recruiting 1 |
| Phase 3 | 2 | Recruiting 1, Unknown 1 |
Follow Locally Advanced Gastric Carcinoma: new trials by email Literature Review of Locally Advanced Gastric Carcinoma trials Research Report on Locally Advanced Gastric Carcinoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Testing the Combination of the Anticancer Drugs Trastuzumab Deruxtecan (DS-8201a) and Azenosertib (ZN-c3) in Patients With Stomach or Other Solid Tumors Azenosertib, Biopsy Procedure, Biospecimen Collection - Clinical Stage III Gastric Cancer AJCC v8, Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 | Phase 1 | Recruiting | National Cancer Institute (NCI) | 48 | 2025-02-03 | 2026-10-27 |
| Olanzapine for the Management of Cancer Associated Appetite Loss in Patients With Advanced Esophagogastric, Hepatopancreaticobiliary, Colorectal or Lung Cancer Olanzapine, Placebo Administration, Questionnaire Administration - Advanced Malignant Solid Neoplasm, Advanced Biliary Tract Carcinoma | Phase 2 | Recruiting | OHSU Knight Cancer Institute | 66 | 2024-07-17 | 2026-07-16 |
| Research on Intelligent Screening and Decision-making for Neoadjuvant Therapy in Locally Advanced Gastric Cancer Based on Multi-omics Integration Locally Advanced Gastric Carcinoma | Unknown | Zhejiang University | 120 | 2024-07-01 | 2024-05-02 | |
| Tirelizumab Combined With Chemotherapy in the Treatment of HER-2 Negative Locally Advanced Gastric Cancer Tirolizumab+SOX/XELOX, SOX/XELOX - Locally Advanced Gastric Carcinoma, HER2 Negative | Phase 2 | Unknown | Lin Chen | 80 | 2023-10-01 | 2024-02-29 |
| Transarterial Neoadjuvant Chemotherapy vs.Traditional Intravenous Chemotherapy For Locally Advanced Gastric Cancer With SOX+PD-1 Oxaliplatin by arterial infusion plus S-1, SOX neoadjuvant, Sintilimab neoadjuvant - Locally Advanced Gastric Carcinoma | Phase 3 | Recruiting | Zhejiang University | 190 | 2023-03-01 | 2026-06-11 |
| First-Line and Neoadjuvant Immunotherapy for Gastric Cancer ICI plus Chemothearpy, Chemotherapy - Advanced Gastric Cancer, Locally Advanced Gastric Carcinoma | Recruiting | Qilu Hospital of Shandong University | 500 | 2022-01-15 | 2024-12-11 | |
| Toripalimab Plus FLOT in Locally Advanced Gastric Cancer FLOT combined with toripalimab - Chemotherapy, Immune Checkpoint Inhibitor | Phase 2 | Recruiting | Henan Cancer Hospital | 60 | 2021-06-25 | 2024-06-06 |
| Measuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair Variations Biopsy Procedure, Biospecimen Collection, Computed Tomography - Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8 | Phase 2 | Active not recruiting | National Cancer Institute (NCI) | 29 | 2021-04-26 | 2026-08-19 |
| Preoperative Stomach Cancer Induction Chemotherapy and Radiation Therapy Arm 1 pre-operative chemoradiation, Arm 2 post operative chemoradiation - Locally Advanced Gastric Carcinoma | Phase 3 | Unknown | Sichuan Provincial People's Hospital | 450 | 2016-09-01 | 2017-08-21 |
| Neoadjuvant Bev Plus DOF vs DOF in LAGC and Its Association With Circulating Tumor Cell Bevacizumab, docetaxel oxaliplatin 5-FU CF, Gastrectomy - Locally Advanced Gastric Carcinoma | Phase 1 / Phase 2 | Completed | Chinese PLA General Hospital | 86 | 2009-02-01 | 2014-04-25 |
Stomach Neoplasms (4) · Neoplasm Metastasis (2) · Anorexia (1) · Breast Neoplasms (1) · Cachexia (1) · Colorectal Neoplasms (1) · Esophageal Neoplasms (1) · Neoplasms (1) · Ovarian Neoplasms (1) · Pancreatic Neoplasms (1) · Prostatic Neoplasms (1) · Weight Loss (1)
Digestive System Diseases (5) · Digestive System Neoplasms (5) · Gastrointestinal Diseases (5) · Gastrointestinal Neoplasms (5) · Neoplasms by Site (5) · Neoplasms (4) · Stomach Diseases (4) · Pathological Conditions, Signs and Symptoms (3) · Neoplastic Processes (2) · Pathologic Processes (2) · Adnexal Diseases (1) · Body Weight (1) · Body Weight Changes (1) · Breast Diseases (1) · Colonic Diseases (1)
Biopsy (2) · Gastrectomy (2) · Magnetic Resonance Spectroscopy (2) · Specimen Handling (2) · Bevacizumab (1) · Drug Therapy (1) · Olanzapine (1) · S 1 (combination) (1) · talazoparib (1) · toripalimab (1) · trastuzumab deruxtecan (1)
National Cancer Institute (NCI) (2) · Zhejiang University (2) · Chinese PLA General Hospital (1) · Henan Cancer Hospital (1) · Lin Chen (1) · OHSU Knight Cancer Institute (1) · Qilu Hospital of Shandong University (1) · Sichuan Provincial People's Hospital (1)
China (7) · United States (3)
A P Chen (1) · Eric Roeland, M.D., FAAHPM, FASCO (1) · Funda Meric-Bernstam (1) · Hongwei Zhang, MD PhD (1) · Lian Liu, MD (1) · Ming Zeng, MD PhD (1) · Nan Du, Phd (1) · Quanli Gao, M.D (1)
P30CA069533 (1), UM1CA186688 (1)