18 completed, 2 recruiting, 2 terminated. 6 Phase 2, 4 Phase 1, 2 Phase 4, 1 Not applicable, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Completed 5, Terminated 1 |
| Phase 1 | 4 | Completed 2, Terminated 2 |
| Phase 4 | 2 | Completed 2 |
| Not applicable | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
Follow Kaposi's Sarcoma: new trials by email Literature Review of Kaposi's Sarcoma trials Research Report on Kaposi's Sarcoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Molecular Characterization of Viral-associated Tumors, Tumors Occurring in the Setting of HIV or Other Immune Disorders and Castleman Disease Human Immunodeficiency Virus, Castleman's Disease | Recruiting | National Cancer Institute (NCI) | 280 | 2017-12-20 | 2026-10-16 | |
| Evaluation of Tc 99m Tilmanocept Localization in Primary Cutaneous Kaposi's Sarcoma and Lymphatic Drainage by SPECT/CT Tc 99m tilmanocept - Kaposi's Sarcoma | Phase 2 | Completed | Navidea Biopharmaceuticals | 5 | 2014-09-01 | 2016-09-27 |
| A Study to Investigate ALDOXORUBICIN in HIV-infected Subjects With Kaposi's Sarcoma 50 mg/m2 aldoxorubicin, 100 mg/m2 aldoxorubicin, 150 mg/m2 aldoxorubicin - Kaposi's Sarcoma, HIV Positive | Phase 2 | Completed | ImmunityBio, Inc. | 15 | 2014-04-03 | 2024-06-11 |
| Antiretroviral Therapy (ART) Alone or With Delayed Chemo Versus ART With Immediate Chemo for Limited AIDS-related Kaposi's Sarcoma efavirenz/emtricitabine/tenofovir disoproxil fumarate, etoposide - HIV-1 Infection, Kaposi's Sarcoma | Phase 3 | Completed | Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections | 192 | 2011-11-18 | 2019-11-14 |
| Effects of Maraviroc (MVC) on HIV-related Kaposi's Sarcoma (KS) Maraviroc - Kaposi's Sarcoma | Phase 2 | Completed | University of California, San Francisco | 13 | 2011-03-09 | 2021-03-05 |
| 124I-FIAU Imaging in EBV and KSHV Associated Cancers FIAU-PET-CT-2, FIAU-PET-CT-4 - Hodgkin Lymphoma, Non Hodgkin Lymphoma | Not applicable | Completed | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 12 | 2010-12-01 | 2018-09-17 |
| PTC299 in Treating Patients With HIV-Related Kaposi Sarcoma VEGF inhibitor PTC299, gene expression analysis, polymerase chain reaction - Kaposi's Sarcoma | Phase 1 / Phase 2 | Terminated | AIDS Malignancy Consortium | 17 | 2008-09-01 | 2018-06-06 |
| Treatment With Indinavir and Chemotherapy for Advanced Classical Kaposi's Sarcoma Indinavir in association with Vinblastina +/- Bleomicina - Kaposi's Sarcoma | Phase 2 | Completed | Barbara Ensoli, MD, PhD | 25 | 2008-06-01 | 2016-08-30 |
| Anti-Retrovirals for Kaposi's Sarcoma Lopinavir/ritonavir plus Emtricitabine/Tenofovir versus Efavirenz plus Emtricitabine/Tenofovir - Kaposi's Sarcoma, HIV Infections | Phase 4 | Completed | University of California, San Francisco | 224 | 2007-04-01 | 2014-08-20 |
| BAY 43-9006 (Sorafenib) to Treat Patients With Kaposi's Sarcoma BAY 43-9006 - Kaposi's Sarcoma, HHV-8 | Phase 1 | Terminated | National Cancer Institute (NCI) | 10 | 2006-02-02 | 2019-12-12 |
| Bevacizumab to Treat Kaposi's Sarcoma in HIV-Positive and HIV-Negative Patients Bevacizumab - Kaposi's Sarcoma, HIV Infections | Phase 2 | Completed | National Cancer Institute (NCI) | 19 | 2003-02-26 | 2017-09-06 |
| HIV/AIDS Kaposis Sarcoma: Comparison of Response to HAART vs HAART Plus CXT Generic HAART Triomune : d4T, 3TC, NVP, Generic HAART Triomune : d4T, 3TC, NVP and chemotherapy ABV - HIV, AIDS | Phase 4 | Completed | University of KwaZulu | 112 | 2003-01-01 | 2010-07-21 |
| Risk Factors for Non-HIV-Related Kaposi s Sarcoma Kaposi's Sarcoma | Completed | National Cancer Institute (NCI) | 1383 | 2002-09-01 | 2021-03-12 | |
| Assessment of Blood Vessel Density in Kaposi's Sarcoma Lesions Kaposi's Sarcoma | Completed | National Cancer Institute (NCI) | 29 | 2001-04-23 | 2020-07-08 | |
| Seroprevalence of Kaposi's Sarcoma Herpes Virus in the United States Kaposi's Sarcoma, Herpesviridae Infection | Completed | National Cancer Institute (NCI) | 20169 | 2001-02-01 | 2008-03-04 | |
| Specimen Collections From Participants With HIV Infection, KSHV Infection, Viral-Related Pre-malignant Lesions and Cancer HIV, Kaposi's Sarcoma | Recruiting | National Cancer Institute (NCI) | 1029 | 2000-12-06 | 2026-10-16 | |
| Effects of Potent Antiretroviral Therapy on Kaposi s Sarcoma HIV Seropositivity, Kaposi's Sarcoma | Completed | National Cancer Institute (NCI) | 24 | 2000-08-07 | 2019-12-12 | |
| Optical Biopsy of Human Skin in Conjunction With Laser Treatment Optical Biopsy imaging - Malignant Melanoma, Merkel Cell Carcinoma | Completed | University of California, Irvine | 113 | 1999-06-01 | 2022-10-20 | |
| Spectroscopy With Surface Coils and Decoupling Proton-decoupled 31P MRS at 1.5T, 1H Spectroscopy at 1.5T and 3T - Adrenal Cortical Cancer, Brain Cancer | Phase 1 | Completed | Memorial Sloan Kettering Cancer Center | 582 | 1997-02-01 | 2015-12-28 |
| Clinical, Laboratory and Epidemiologic Pilot Studies of Individuals at High Risk for Viral-Associated Cancers Acquired Immunodeficiency Syndrome, Kaposi's Sarcoma | Completed | National Cancer Institute (NCI) | 24 | 1996-12-24 | 2017-07-02 |
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Sarcoma, Kaposi (22) · Acquired Immunodeficiency Syndrome (10) · HIV Infections (7) · Neoplasms (5) · Carcinoma, Squamous Cell (2) · HIV Seropositivity (2) · Hodgkin Disease (2) · Lymphoma (2) · Lymphoma, Non-Hodgkin (2) · Lymphoma, Primary Effusion (2) · Sarcoma (2) · AIDS-related Kaposi sarcoma (1) · Alcoholism (1) · Brain Neoplasms (1) · Breast Neoplasms (1)
DNA Virus Infections (22) · Infections (22) · Neoplasms by Histologic Type (22) · Neoplasms, Connective and Soft Tissue (22) · Neoplasms, Vascular Tissue (22) · Herpesviridae Infections (21) · Virus Diseases (21) · Sarcoma (20) · Neoplasms (17) · Immune System Diseases (14) · Genital Diseases (13) · Urogenital Diseases (13) · Blood-Borne Infections (12) · Communicable Diseases (12) · Lentivirus Infections (12)
Association (1) · Bevacizumab (1) · Biopsy (1) · Efavirenz, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination (1) · Emtricitabine (1) · Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination (1) · Etoposide (1) · Gene Expression Profiling (1) · Immunohistochemistry (1) · Indinavir (1) · Interleukin-2 (1) · Lopinavir (1) · Maraviroc (1) · Muromonab-CD3 (1) · Nevirapine (1)
National Cancer Institute (NCI) (10) · University of California, San Francisco (2) · AIDS Malignancy Consortium (1) · Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections (1) · Barbara Ensoli, MD, PhD (1) · ImmunityBio, Inc. (1) · Memorial Sloan Kettering Cancer Center (1) · National Human Genome Research Institute (NHGRI) (1) · Navidea Biopharmaceuticals (1) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (1) · University of California, Irvine (1) · University of KwaZulu (1)
United States (17) · Italy (2) · South Africa (2) · Uganda (2) · Brazil (1) · Kenya (1) · Malawi (1) · Peru (1)
Robert Yarchoan, M.D. (6) · Anisa Mosam, FC Derm,PhD (1) · Bonnie C Abbruzzese, MS, RD, CCRA (1) · Dr. Edward K Mbidde, MBChB, MMed (1) · Dr. Jeffrey N Martin, MD, MPH (1) · Jason Koutcher, MD, PhD (1) · John S Nelson, M.D,Ph.D (1) · Lucia Brambilla, MD (1) · Mina C Hosseinipour, M.D. (1) · Patrick Unemori, MD (1) · Richard Ambinder, M.D. (1) · Sam M Mbulaiteye, M.D. (1) · Susan E. Krown, MD (1) · Thomas B Campbell, M.D. (1) · Toby Maurer, MD (1)
PMID 37740179, PMID 41845569, PMID 15633090, PMID 15652610, PMID 15750399, PMID 17269969, PMID 22430271, PMID 28341759, PMID 29365083, PMID 30354935, PMID 31520741, PMID 37368929, PMID 38941593
P01CA015396 (1), U01AI068636 (1), U01CA121947 (1)