7 completed, 6 recruiting, 3 active not recruiting, 1 not yet recruiting. 9 Phase 2, 7 Phase 1, 2 Not applicable, 1 Early Phase 1.
Follow Lymphoma, Primary Effusion: new trials by email Literature Review of Lymphoma, Primary Effusion trials Research Report on Lymphoma, Primary Effusion
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| AMC 120, Glofitamab Plus Chemoimmunotherapy in Newly Diagnosed HIV-Associated Large B-Cell Lymphoma (The "Glofit-RCHOP Study") Biopsy Procedure, Biospecimen Collection, Bone Marrow Aspiration - AIDS-Related Diffuse Large B-cell Lymphoma, Diffuse Large B-Cell Lymphoma, Not Otherwise Specified | Phase 1 | Recruiting | National Cancer Institute (NCI) | 15 | 2027-07-05 | 2026-10-28 |
| Exploratory Study on the Treatment of EB Virus Positive HIV Associated Lymphoma With EBV mRNA Vaccine EBV mRNA vaccine - HIV Associated Lymphoma | Early Phase 1 | Not yet recruiting | West China Hospital | 6 | 2026-05-01 | 2026-05-01 |
| Daratumumab for Relapsed/Refractory Primary Effusion Lymphoma, Plasmablastic Lymphoma, and Multicentric Castleman Disease Daratumumab SC - Lymphoma, Primary Effusion | Phase 2 | Recruiting | National Cancer Institute (NCI) | 40 | 2024-07-10 | 2026-10-16 |
| T-Cell Therapy (EB103) in Adults With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma (NHL) EB103 - B-Cell Non-Hodgkin's Lymphoma (NHL), Lymphoma, Non-Hodgkins | Phase 1 / Phase 2 | Recruiting | Estrella Immunopharma, Inc. | 27 | 2024-06-01 | 2026-10-01 |
| Study of SGR-1505 in Mature B-Cell Neoplasms SGR-1505 - Mature B-Cell Neoplasm, Non Hodgkin Lymphoma | Phase 1 | Recruiting | Schrödinger, Inc. | 98 | 2023-04-10 | 2026-02-13 |
| Natural History of KSHV-Associated Multicentric Castleman s Disease Multicentric Castleman s Disease | Recruiting | National Cancer Institute (NCI) | 195 | 2021-11-17 | 2026-10-16 | |
| HIV Antigen-specific T-cells Targeting Conserved Epitopes (HST-NEETs) BMTCTN1903 HST-NEETs, Bone Marrow Transplant - HIV Associated Lymphoma | Phase 2 | Completed | Catherine Bollard | 12 | 2021-10-25 | 2026-06-29 |
| Observational Study of People Living With HIV Treated With CD19-directed CAR T Cell Leukemia, Leukemia, Lymphoblastic | Completed | AIDS Malignancy Consortium | 35 | 2021-05-22 | 2026-10-28 | |
| Assessment of Bone Mineral Density in People Living With HIV and KSHV Associated Malignancies: A Retrospective Longitudinal Analysis Kaposi Sarcoma, KSHV Associated Multicentric Castleman Disease | Active not recruiting | National Cancer Institute (NCI) | 40 | 2021-02-04 | 2026-08-25 | |
| Nivolumab With or Without Varlilumab in Treating Patients With Relapsed or Refractory Aggressive B-cell Lymphomas Nivolumab, Varlilumab - ALK-Positive Large B-Cell Lymphoma, Diffuse Large B-Cell Lymphoma Activated B-Cell Type | Phase 2 | Active not recruiting | National Cancer Institute (NCI) | 54 | 2018-12-21 | 2026-10-26 |
| Lenalidomide Combined With Modified DA-EPOCH and Rituximab (EPOCH-R2) in Primary Effusion Lymphoma or KSHV-associated Large Cell Lymphoma Lenalidomide, Rituximab, Prednisone - Primary Effusion Lymphoma, B-Cell Neoplasm | Phase 1 / Phase 2 | Active not recruiting | National Cancer Institute (NCI) | 17 | 2017-07-03 | 2026-10-20 |
| Study to Evaluate Safety and Tolerability of XmAb13676 (Plamotamab) in Patients With CD20-expressing Hematologic Malignancies XmAb13676 - B-cell Non-Hodgkins Lymphoma, Chronic Lymphocytic Leukemia | Phase 1 | Completed | Xencor, Inc. | 154 | 2016-10-01 | 2024-11-13 |
| Salvia Hispanica Seed in Reducing Risk of Disease Recurrence in Patients With Non-Hodgkin Lymphoma Laboratory Biomarker Analysis, Quality-of-Life Assessment, Questionnaire Administration - Adult Nasal Type Extranodal NK/T-Cell Lymphoma, Adult T-Cell Leukemia/Lymphoma | Not applicable | Completed | Mayo Clinic | 29 | 2016-01-19 | 2019-11-15 |
| Study of Pomalidomide Combined With Modified DA-EPOCH and Rituximab in KSHV-Associated Lymphomas Pomalidomide, Rituximab, Prednisone - Large Cell Lymphoma Arising in KSHV-associated Multicentric Castleman Disease, Primary Effusion Lymphoma | Phase 1 / Phase 2 | Withdrawn | National Cancer Institute (NCI) | 2014-08-15 | 2018-08-31 | |
| 124I-FIAU Imaging in EBV and KSHV Associated Cancers FIAU-PET-CT-2, FIAU-PET-CT-4 - Hodgkin Lymphoma, Non Hodgkin Lymphoma | Not applicable | Completed | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 12 | 2010-12-01 | 2018-09-17 |
| Vorinostat and Combination Chemotherapy With Rituximab in Treating Patients With HIV-Related Diffuse Large B-Cell Non-Hodgkin Lymphoma or Other Aggressive B-Cell Lymphomas Cyclophosphamide, Doxorubicin Hydrochloride, Etoposide - AIDS-Related Plasmablastic Lymphoma, AIDS-Related Primary Effusion Lymphoma | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 107 | 2010-10-06 | 2023-11-21 |
| Autologous Peripheral Stem Cell Transplant in Treating Patients With Non-Hodgkin's Lymphoma or Hodgkin's Lymphoma carmustine, cyclophosphamide, etoposide - Lymphoma | Phase 2 | Completed | Masonic Cancer Center, University of Minnesota | 473 | 2005-08-24 | 2020-07-14 |
| Pegylated Liposomal Doxorubicin (Doxil) With Rituximab in Relapsed AIDS-Related Non-Hodgkin's Lymphomas Pegylated Liposomal Doxorubicin (Doxil) and Rituximab - Non-Hodgkin's Lymphoma, Burkitt Lymphoma | Phase 2 | Terminated | University of Southern California | 15 | 2005-04-01 | 2014-05-22 |
| Specimen Collections From Participants With HIV Infection, KSHV Infection, Viral-Related Pre-malignant Lesions and Cancer HIV, Kaposi's Sarcoma | Recruiting | National Cancer Institute (NCI) | 1029 | 2000-12-06 | 2026-10-16 |
Lymphoma, Non-Hodgkin (8) · Lymphoma, Large B-Cell, Diffuse (6) · Burkitt Lymphoma (5) · Lymphoma (5) · Lymphoma, B-Cell (5) · Lymphoma, Follicular (5) · Plasmablastic Lymphoma (5) · Sarcoma, Kaposi (4) · Acquired Immunodeficiency Syndrome (3) · Leukemia, Lymphocytic, Chronic, B-Cell (3) · Lymphoma, B-Cell, Marginal Zone (3) · Lymphoma, Mantle-Cell (3) · Multi-centric Castleman's Disease (3) · HIV Infections (2)
Hemic and Lymphatic Diseases (19) · Immune System Diseases (19) · Immunoproliferative Disorders (19) · Lymphatic Diseases (19) · Lymphoproliferative Disorders (19) · Neoplasms by Histologic Type (19) · Neoplasms (18) · Lymphoma (14) · Lymphoma, B-Cell (14) · Infections (11) · Lymphoma, Non-Hodgkin (11) · Virus Diseases (10) · DNA Virus Infections (9) · Herpesviridae Infections (9) · Epstein-Barr Virus Infections (5)
Cyclophosphamide (5) · Rituximab (5) · Doxorubicin (4) · Etoposide (4) · Prednisone (4) · Vincristine (4) · CT-P10 (2) · deltacortene (2) · liposomal doxorubicin (2) · prednylidene (2) · Biopsy (1) · Bone Marrow Transplantation (1) · Bronchoscopy (1) · Carmustine (1) · Cytarabine (1)
National Cancer Institute (NCI) (9) · AIDS Malignancy Consortium (1) · Catherine Bollard (1) · Estrella Immunopharma, Inc. (1) · Masonic Cancer Center, University of Minnesota (1) · Mayo Clinic (1) · Schrödinger, Inc. (1) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (1) · University of Southern California (1) · West China Hospital (1) · Xencor, Inc. (1)
United States (17) · France (2) · Italy (1) · Moldova (1) · Poland (1) · Romania (1) · South Korea (1) · Spain (1) · Ukraine (1) · United Kingdom (1)
Ramya M Ramaswami, M.D. (2) · Robert Yarchoan, M.D. (2) · Anil Tulpule, MD (1) · Chet Bohac, PharmD, MD, MSc (1) · Frank G Basile, M.D. (1) · Juan C Ramos (1) · Pei Wang, PhD (1) · Ramya Ramaswami, MBBS, MPH (1) · Richard Ambinder, M.D. (1) · Stefan Barta, MD (1) · Stefan K Barta (1) · Stephen M Ansell (1) · Steve Devine, MD, MS (1) · Thomas S Uldrick, M.D. (1) · Thomas Witzig (1)
PMID 32430507, PMID 37740179, PMID 38941593, PMID 41845569
UM1CA121947 (2), P01CA015396 (1), P30CA015083 (1), U10HL069294 (1), UM1CA186686 (1), UM1CA186709 (1)