6 completed, 3 recruiting, 3 unknown, 2 withdrawn. 16 Phase 1, 6 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 16 | Completed 6, Recruiting 3, Unknown 3, Withdrawn 2, Not yet recruiting 1, Terminated 1 |
| Phase 2 | 6 | Completed 2, Unknown 2, Recruiting 1, Terminated 1 |
Follow Intestinal Fistula: new trials by email Literature Review of Intestinal Fistula trials Research Report on Intestinal Fistula
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Platelet-Rich Plasma Injection on Wound Healing After Fistulotomy for Simple Anal Fistula Randomized Controlled Trial (RCT) PRP injection - Simple Anal Fistula | Phase 1 | Not yet recruiting | Assiut University | 70 | 2025-12-01 | 2025-11-25 |
| Tissue Therapy of Transsphincteric Anal Fistula ADRC injection, ADRC001 injection - Anal Fistula | Phase 1 / Phase 2 | Recruiting | University of Southern Denmark | 75 | 2024-10-09 | 2024-11-05 |
| Evaluate the Distribution and Dynamic Behavior of TH-SC01 Cells in Vivo in Patients With Perianal Fistula Mesenchymal Stem Cells (MSCs) - Anal Fistula, Complex Perianal Fistulas | Phase 1 | Unknown | Jiangsu Topcel-KH Pharmaceutical Co., Ltd. | 8 | 2024-04-08 | 2024-06-12 |
| Treatment of Ano-perineal Fistulas Resistant to Surgical Treatment with a Gel and Plug of Wharton's Jelly SygeLIX-F + SygeLIX-G - Anal Fistula | Phase 1 | Completed | TBF Genie Tissulaire | 9 | 2023-06-27 | 2024-11-14 |
| Mesenchymal Stem Cells (MSCs) for Perianal Fistula OSSM-001, Placebo - Rectal Fistula | Phase 1 | Withdrawn | Ossium Health, Inc. | 2022-08-01 | 2022-12-23 | |
| Safety of Allogeneic Human Umbilical Cord Mesenchymal Stem Cells (UC-MSCs) to Treat Perianal Fistulas w/ Crohn's Disease PF2020-CELL (UC-MSCs) - Allogeneic Human Umbilical Cord Mesenchymal Stem Cells - Perianal Fistula Due to Crohn's Disease, Fistula in Ano | Phase 1 | Recruiting | CryoCord Sdn Bhd | 5 | 2022-03-01 | 2025-05-11 |
| Mesenchymal Stem Cells for the Treatment of Pouch Fistulas in Crohn's mesenchymal stem cells (MSCs) - Crohn's Disease, Fistula | Phase 1 | Withdrawn | The Cleveland Clinic | 2021-06-01 | 2026-04-15 | |
| Mesenchymal Stem Cells for the Treatment of Rectovaginal Fistulas in Participants With Crohn's Disease Mesenchymal Stem Cells, Placebo - Rectovaginal Fistula, Crohn Disease | Phase 1 / Phase 2 | Terminated | Anthony Lembo | 20 | 2020-10-28 | 2026-04-16 |
| E-CEL UVEC as an Adjunct Cell Therapy for Treatment of Anal Fistulas E-CEL UVEC - Anal Fistula | Phase 1 | Recruiting | Weill Medical College of Cornell University | 39 | 2020-01-22 | 2025-11-18 |
| Pediatric MSC-AFP Sub-study for Crohn's Fistula MSC-AFP - Fistula in Ano, Crohn Disease | Phase 1 | Completed | Mayo Clinic | 1 | 2018-07-23 | 2024-03-13 |
| Autologous Adipose-derived Regenerative Cells Injection for Treatment of Radiation-induced Rectovaginal Fistula Injection of autologous regenerative cells of adipose tissue - Rectovaginal Fistula | Phase 1 | Completed | South Ural State Medical University | 16 | 2017-08-01 | 2020-01-27 |
| Stromal Vascular Fraction (SVF) for Treatment of Recto-vaginal Fistula Adipose-derived stem cells without expanded - Recto-vaginal Fistula | Phase 1 / Phase 2 | Unknown | Instituto de Investigación Hospital Universitario La Paz | 10 | 2011-12-01 | 2012-03-08 |
| Stromal Vascular Fraction (SVF) for Treatment of Enterocutaneous Fistula (HULPUTC) Adipose-derived stem cells without expanded - Enterocutaneous Fistula | Phase 1 / Phase 2 | Unknown | Instituto de Investigación Hospital Universitario La Paz | 10 | 2011-12-01 | 2012-04-25 |
| Allogenic Stem Cells Derived From Lipoaspirates for the Treatment of Recto-vaginal Fistulas Associated to Crohn's Disease (ALOREVA) Expanded allogenic adipose-derived adult stem cells - Rectovaginal Fistula, Crohn Disease | Phase 1 / Phase 2 | Completed | Fundacion para la Investigacion Biomedica del Hospital Universitario la Paz | 10 | 2009-09-01 | 2012-01-26 |
| Study to Assess the Safety and Efficacy of Expanded Allogenic Adipose-derived Stem Cells (eASCs) (Cx601), for Treatment of Complex Perianal Fistulas in Perianal Crohn's Disease. Cx601 - Crohn's Disease, Anal Fistula | Phase 1 / Phase 2 | Completed | Tigenix S.A.U. | 24 | 2009-06-01 | 2019-04-12 |
| Autologous Fibrin Glues for Fistulas Closure Autologous platelet-rich fibrin glue (PRFG), Octreotide - Enterocutaneous Fistulas, Intra-abdominal Infection | Phase 1 | Completed | Jinling Hospital, China | 122 | 2008-01-01 | 2013-02-26 |
Rectal Fistula (10) · Crohn Disease (7) · Rectovaginal Fistula (4) · Fistula (3) · Intraabdominal Infections (1)
Digestive System Diseases (16) · Digestive System Fistula (16) · Gastrointestinal Diseases (16) · Intestinal Diseases (16) · Pathological Conditions, Anatomical (16) · Pathological Conditions, Signs and Symptoms (16) · Rectal Diseases (14) · Fistula (13) · Gastroenteritis (7) · Inflammatory Bowel Diseases (7) · Female Urogenital Diseases (4) · Female Urogenital Diseases and Pregnancy Complications (4) · Genital Diseases (4) · Genital Diseases, Female (4)
Lipectomy (1) · Octreotide (1) · lactitol (1)
Instituto de Investigación Hospital Universitario La Paz (2) · Anthony Lembo (1) · Assiut University (1) · CryoCord Sdn Bhd (1) · Fundacion para la Investigacion Biomedica del Hospital Universitario la Paz (1) · Jiangsu Topcel-KH Pharmaceutical Co., Ltd. (1) · Jinling Hospital, China (1) · Mayo Clinic (1) · Ossium Health, Inc. (1) · South Ural State Medical University (1) · TBF Genie Tissulaire (1) · The Cleveland Clinic (1) · Tigenix S.A.U. (1) · University of Southern Denmark (1) · Weill Medical College of Cornell University (1)
Spain (4) · United States (3) · China (2) · Denmark (1) · France (1) · Malaysia (1) · Russia (1)
Amy Lightner, MD (3) · April Camilla Roslani, Prof. Dr. (1) · Georgy Dimov, PhD (1) · Jeffrey W Milsom, MD (1) · Mariano Garcia-Arranz, Doctor (1) · Michael C Stephens (1) · Sagar Munjal, MD (1) · Viacheslav Vasilyev, PhD (1) · Zhanna Teryushkova, PhD (1)