5 completed, 4 unknown, 1 recruiting, 1 terminated. 11 Phase 2, 6 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 11 | Completed 5, Unknown 4, Recruiting 1, Terminated 1 |
| Phase 1 | 6 | Completed 2, Unknown 2, Recruiting 1, Terminated 1 |
Follow Intestinal Fistula: new trials by email Literature Review of Intestinal Fistula trials Research Report on Intestinal Fistula
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluating an rhPDGF-BB-enhanced Collagen Plug for Perianal Fistula Healing RhPDGF-BB - Anal Fistula, Complex Perianal Fistula | Phase 2 | Completed | Alexander Hawkins | 13 | 2024-11-25 | 2026-08-03 |
| Tissue Therapy of Transsphincteric Anal Fistula ADRC injection, ADRC001 injection - Anal Fistula | Phase 1 / Phase 2 | Recruiting | University of Southern Denmark | 75 | 2024-10-09 | 2024-11-05 |
| Mesenchymal Stem Cells for the Treatment of Rectovaginal Fistulas in Participants With Crohn's Disease Mesenchymal Stem Cells, Placebo - Rectovaginal Fistula, Crohn Disease | Phase 1 / Phase 2 | Terminated | Anthony Lembo | 20 | 2020-10-28 | 2026-04-16 |
| Feasibility and Safety of Additional Injection of Autologous Platelet-rich Stroma to Surgical Treatment of Rectovaginal Fistulas autologous platelet-rich stroma - Rectovaginal Fistula, Anovaginal Fistula | Phase 2 | Completed | Erasmus Medical Center | 21 | 2019-01-11 | 2025-01-29 |
| A Prospective European Post-Market Clinical Evaluation of the CuraSeal Percutaneous Intraluminal Closure System for Anorectal Fistulas PICS-AF Device, Historical Controls Treated with Commercially Available Fistula Plugs - Anal Fistulas, Rectal Fistulas | Phase 2 | Unknown | Curaseal Inc. | 30 | 2015-05-01 | 2015-05-28 |
| Stromal Vascular Fraction (SVF) for Treatment of Recto-vaginal Fistula Adipose-derived stem cells without expanded - Recto-vaginal Fistula | Phase 1 / Phase 2 | Unknown | Instituto de Investigación Hospital Universitario La Paz | 10 | 2011-12-01 | 2012-03-08 |
| Stromal Vascular Fraction (SVF) for Treatment of Enterocutaneous Fistula (HULPUTC) Adipose-derived stem cells without expanded - Enterocutaneous Fistula | Phase 1 / Phase 2 | Unknown | Instituto de Investigación Hospital Universitario La Paz | 10 | 2011-12-01 | 2012-04-25 |
| Allogenic Stem Cells Derived From Lipoaspirates for the Treatment of Recto-vaginal Fistulas Associated to Crohn's Disease (ALOREVA) Expanded allogenic adipose-derived adult stem cells - Rectovaginal Fistula, Crohn Disease | Phase 1 / Phase 2 | Completed | Fundacion para la Investigacion Biomedica del Hospital Universitario la Paz | 10 | 2009-09-01 | 2012-01-26 |
| Study to Assess the Safety and Efficacy of Expanded Allogenic Adipose-derived Stem Cells (eASCs) (Cx601), for Treatment of Complex Perianal Fistulas in Perianal Crohn's Disease. Cx601 - Crohn's Disease, Anal Fistula | Phase 1 / Phase 2 | Completed | Tigenix S.A.U. | 24 | 2009-06-01 | 2019-04-12 |
| Success Rate, Continence, and Quality of Life With a Bioprosthetic Plug for Treating Complex Anal Fistula Anal fistula plug - Complex Anal Fistula | Phase 2 | Completed | University Hospital, Basel, Switzerland | 46 | 2007-01-01 | 2013-05-17 |
| Autologous Stem Cells Derived From Lipoaspirates for the Non-Surgical Treatment of Complex Perianal Fistula Non-surgical autologous implant of ASCs - Anal Fistula | Phase 2 | Unknown | Cellerix | 50 | 2004-10-01 | 2005-06-24 |
Rectal Fistula (6) · Rectovaginal Fistula (4) · Crohn Disease (3) · Fistula (2) · Osteogenesis Imperfecta, Type IV (1)
Digestive System Diseases (11) · Digestive System Fistula (11) · Gastrointestinal Diseases (11) · Intestinal Diseases (11) · Pathological Conditions, Anatomical (11) · Pathological Conditions, Signs and Symptoms (11) · Rectal Diseases (10) · Fistula (9) · Female Urogenital Diseases (4) · Female Urogenital Diseases and Pregnancy Complications (4) · Genital Diseases (4) · Genital Diseases, Female (4) · Rectal Fistula (4) · Urogenital Diseases (4)
Becaplermin (1) · Lipectomy (1)
Instituto de Investigación Hospital Universitario La Paz (2) · Alexander Hawkins (1) · Anthony Lembo (1) · Cellerix (1) · Curaseal Inc. (1) · Erasmus Medical Center (1) · Fundacion para la Investigacion Biomedica del Hospital Universitario la Paz (1) · Tigenix S.A.U. (1) · University Hospital, Basel, Switzerland (1) · University of Southern Denmark (1)
Spain (6) · United States (2) · Denmark (1) · Netherlands (1) · Switzerland (1)
Alexander T Hawkins (1) · Amy Lightner, MD (1) · Damian Garcia-Olmo, Prof. (1) · Mariano Garcia-Arranz, Doctor (1) · Michel Adamina, MD, PD, MSc (1) · Oddeke van Ruler, GI- surgeon, MD, PhD (1)