11 completed, 5 recruiting, 2 active not recruiting, 2 not yet recruiting. 11 Not applicable, 4 Phase 2, 2 Phase 1, 2 Phase 3, 1 Phase 4.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| SniffTrain: Effectiveness of Sniff Training in the Treatment of Post-Viral Anosmia Sniff Training Kits - Post-viral Anosmia, Anosmia | Not applicable | Not yet recruiting | University of Virginia | 204 | 2027-01-05 | 2026-10-05 |
| Firefighter's Longitudinal Airway and Respiratory Exposome/Multiome Study (FLARES) Anosmia, Chronic Obstructive Pulmonary Disease | Enrolling by invitation | National Institute of Allergy and Infectious Diseases (NIAID) | 350 | 2026-11-03 | 2026-10-29 | |
| Artificial Intelligence-based Parkinson's Disease Risk Assessment (AI-PRA) Study Smartwatch and phone app - Parkinson Disease (PD), REM Sleep Behavior Disorder (iRBD) | Not yet recruiting | Queen Mary University of London | 60 | 2026-10-01 | 2026-10-02 | |
| Slow-SPEED UK: A Double-Blind Randomised Feasibility Trial Slow-SPEED app - Hyposmia, Olfactory Dysfunction | Not applicable | Recruiting | Queen Mary University of London | 110 | 2026-05-27 | 2026-06-29 |
| Topical Versus Injection PRP for Olfactory Dysfunction Intranasal Injection of Autologous PRP, Carrier-Assisted Topical Application of Autologous PRP, platelet-rich plasma - Olfactory Dysfunction, Anosmia | Phase 3 | Recruiting | Taipei Veterans General Hospital, Taiwan | 60 | 2025-09-11 | 2026-10-05 |
| Scents of Progress: Leveraging a Novel Device for Olfactory Training in Older Adults Sudoku Puzzles, ScentCare (Olfactory Training Device) - Olfactory Dysfunction, Smell Loss | Not applicable | Recruiting | Johns Hopkins University | 60 | 2025-04-15 | 2026-04-13 |
| Theophylline Nasal Spray for PD-Related Hyposmia and Anosmia CYR-064 - Hyposmia, Anosmia | Phase 1 | Withdrawn | University of Nebraska | 2025-04-01 | 2025-03-13 | |
| Treatment of Olfactory Dysfunction Using Vagus Nerve Stimulation Nasal Insert + VNS, Nasal Insert - Hyposmia | Not applicable | Active not recruiting | Karolinska Institutet | 40 | 2025-03-15 | 2025-08-27 |
| Treatment of Postviral Olfactory Dysfunction Nose plug, Regular olfactory training - Hyposmia | Not applicable | Completed | Karolinska Institutet | 120 | 2023-10-17 | 2025-09-03 |
| Study of CYR-064 Versus Placebo in Patients. CYR-064 - Hyposmia | Phase 2 | Completed | Cyrano Therapeutics, Inc. | 151 | 2023-09-26 | 2026-08-31 |
| The Vietnamese Smell Identification Test in the Diagnosis of Parkinson's Disease The Vietnamese Smell Identification test (VSIT), the Brief Smell Identification test (BSIT) - Hyposmia, Parkinson Disease | Unknown | University Medical Center Ho Chi Minh City (UMC) | 218 | 2023-05-05 | 2023-11-14 | |
| Stellate Ganglion Block for COVID-19-Induced Olfactory Dysfunction Stellate Ganglion Block - Anosmia, Hyposmia | Phase 1 / Phase 2 | Completed | Washington University School of Medicine | 20 | 2022-09-01 | 2026-02-12 |
| Olfactory Training in COVID-19 Associated Loss of Smell Sniffin' sticks Duftquartett - COVID-19, Hyposmia | Not applicable | Completed | Medical University Innsbruck | 70 | 2022-08-10 | 2025-04-23 |
| Olfactory Training on Smell Dysfunction Patients in HK Olfactory Training, Control - Olfaction Disorders, Smell Disorders | Not applicable | Recruiting | Pamela Youde Nethersole Eastern Hospital | 80 | 2022-07-01 | 2025-06-03 |
| Olfactory Training as a Treatment for Olfactory Dysfunction Post COVID-19 Smell training - Hyposmia, COVID-19 | Not applicable | Recruiting | Université du Québec à Trois-Rivières | 70 | 2022-05-31 | 2026-07-31 |
| Efficacy of Gabapentin for Post-Covid-19 Olfactory Dysfunction Gabapentin gelatin capsules 300mg, Placebo - COVID-19, Olfactory Disorder | Phase 2 | Completed | Washington University School of Medicine | 68 | 2022-01-10 | 2025-03-04 |
| Mechanical and Sensorial Training in the Olfactive Rehabilitation of Patients With Total Laryngectomy DosMedical Smell Training Set, Nasal Airflow Inducing Maneuver - Cognitive Aging, Hyposmia | Not applicable | Active not recruiting | University Hospital of Mont-Godinne | 16 | 2021-09-07 | 2025-08-14 |
| Study of Olfactory Disorders in Patients With Cardiac Amyloidosis Sniffin's stick test - Amyloidosis, Cardiac Amyloidosis | Not applicable | Completed | Assistance Publique - Hôpitaux de Paris | 51 | 2021-03-22 | 2026-02-11 |
| Smell in Covid-19 and Efficacy of Nasal Theophylline Theophylline Powder, Placebo Comparator - Covid19, Anosmia | Phase 2 | Completed | Washington University School of Medicine | 51 | 2021-03-15 | 2023-05-24 |
| Visual-OLfactory Training in Participants With COVID-19 Resultant Loss of Smell Smell Training - Anosmia, Covid19 | Not applicable | Completed | Washington University School of Medicine | 240 | 2021-01-11 | 2022-06-21 |
Showing 20 of 23. Sign in to see all of them.
Anosmia (23) · Olfaction Disorders (9) · COVID-19 (8) · Parkinson Disease (3) · Ageusia (2) · Amyloid Neuropathies, Familial (1) · Amyloidosis (1) · Asthma (1) · Motor Activity (1) · Patient Compliance (1) · Pulmonary Disease, Chronic Obstructive (1) · REM Sleep Behavior Disorder (1) · Sensation Disorders (1) · Taste Disorders (1)
Nervous System Diseases (23) · Neurologic Manifestations (23) · Pathological Conditions, Signs and Symptoms (23) · Signs and Symptoms (23) · Sensation Disorders (22) · Olfaction Disorders (14) · Lung Diseases (9) · Respiratory Tract Diseases (9) · Coronaviridae Infections (8) · Coronavirus Infections (8) · Infections (8) · Nidovirales Infections (8) · Pneumonia (8) · Pneumonia, Viral (8) · RNA Virus Infections (8)
Olfactory Training (4) · Insulin (1) · Mepivacaine (1) · co-ultraPEALut (1)
Washington University School of Medicine (4) · Karolinska Institutet (2) · Queen Mary University of London (2) · Assistance Publique - Hôpitaux de Paris (1) · Cyrano Therapeutics, Inc. (1) · Johns Hopkins University (1) · Medical University Innsbruck (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · Pamela Youde Nethersole Eastern Hospital (1) · Taichung Veterans General Hospital (1) · Taipei Veterans General Hospital, Taiwan (1) · Universidad Panamericana (1) · University Hospital of Mont-Godinne (1) · University Medical Center Ho Chi Minh City (UMC) (1) · University Of Perugia (1)
United States (8) · France (2) · Sweden (2) · Taiwan (2) · United Kingdom (2) · Austria (1) · Belgium (1) · Canada (1) · Hong Kong (1) · Italy (1) · Mexico (1) · Spain (1) · Vietnam (1)
Alastair J Noyce, BMedSci, MBBS, MSc, MRCP, PhD (1) · Beatrice Heim, MD PhD (1) · Danielle C Flood, M.D. (1) · Jay F Piccirillo, M.D., FACS (1) · Jay F Piccirillo, MD (1) · Jay F. Piccirillo, M.D., FACS (1) · Johan N Lundstrom (1) · Johannes A Frasnelli, PhD (1) · Kai Chuen Fergus Wong, FRCSEd(ORL) (1) · Mara Seier, MD (1) · Mas Takashima, MD (1) · Ngoc Tai Tran, Doctor (1) · Nicholas Rowan, M.D. (1) · Rong-San Jiang, M.D., Ph.D. (1) · Steven Munger (1)
PMID 18377764, PMID 19359985, PMID 21191261, PMID 22377744, PMID 23165381, PMID 23731850, PMID 27923495, PMID 29557250, PMID 33862126, PMID 35797024, PMID 36062970, PMID 36580304, PMID 37733356, PMID 40278843, PMID 40436445, PMID 42448717
2023 (2)