Hyper-IgM Immunodeficiency Syndrome: Clinical Trials

3 trials for Hyper-IgM Immunodeficiency Syndrome, newest first

ClinicalTrials Daily  ·  Areas  ·  Conditions  ·  Drugs  ·  Sponsors  ·  

3 completed. 3 Phase 1, 2 Phase 2.

By phase and status

PhaseTrialsStatus
Phase 13Completed 3
Phase 22Completed 2

Follow Hyper-IgM Immunodeficiency Syndrome: new trials by email Literature Review of Hyper-IgM Immunodeficiency Syndrome trials Research Report on Hyper-IgM Immunodeficiency Syndrome

Trials (filtered) newest first · largest first

All 3 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
A Study of CDX-1140 (CD40) as Monotherapy or in Combination in Patients With Advanced Malignancies
CDX-1140, CDX-301, pembrolizumab - Melanoma, Non-small Cell Lung Cancer
Phase 1CompletedCelldex Therapeutics1322017-12-012024-03-28
Pilot Study Related to the Effect of Clopidogrel on Plasmatic Soluble CD40 Ligand During Systemic Lupus Erythematous
Treatment by clopidogrel - Systemic Lupus Erythematous
Phase 1 / Phase 2CompletedUniversity Hospital, Bordeaux182015-08-192026-05-14
Unrelated Hematopoietic Stem Cell Transplantation(HSCT) for Genetic Diseases of Blood Cells
Hematopoietic stem cell transplantation - Sickle Cell Disease, Thalassemia
Phase 1 / Phase 2CompletedChildren's Hospital Los Angeles252008-08-012016-06-23

Narrower conditions

Anemia (1)  ·  Anemia, Dyserythropoietic, Congenital (1)  ·  Anemia, Sickle Cell (1)  ·  Bile Duct Neoplasms (1)  ·  Breast Neoplasms (1)  ·  Carcinoma, Non-Small-Cell Lung (1)  ·  Carcinoma, Renal Cell (1)  ·  Chediak-Higashi Syndrome (1)  ·  Cholangiocarcinoma (1)  ·  Colorectal Neoplasms (1)  ·  Congenital amegakaryocytic thrombocytopenia (1)  ·  Esophageal Neoplasms (1)  ·  Fallopian Tube Neoplasms (1)  ·  Fucosidosis (1)

Broader conditions

Blood Protein Disorders (3)  ·  Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3)  ·  Dysgammaglobulinemia (3)  ·  Hematologic Diseases (3)  ·  Hemic and Lymphatic Diseases (3)  ·  Immune System Diseases (3)  ·  Immunologic Deficiency Syndromes (3)  ·  Primary Immunodeficiency Diseases (3)  ·  Genetic Diseases, Inborn (2)  ·  Immunoproliferative Disorders (2)  ·  Lymphatic Diseases (2)  ·  Skin and Connective Tissue Diseases (2)  ·  Adenocarcinoma (1)  ·  Adnexal Diseases (1)  ·  Agranulocytosis (1)

Interventions

Drug Therapy (1)  ·  Hematopoietic Stem Cell Transplantation (1)  ·  pembrolizumab (1)

Sponsors

Celldex Therapeutics (1)  ·  Children's Hospital Los Angeles (1)  ·  University Hospital, Bordeaux (1)

Countries

United States (2)  ·  France (1)

Top investigators

Hisham Abdel-Azim, MD (1)

Results publications

PMID 29635077, PMID 33152483

NIH funding

2014 (1)