1 completed, 1 not yet recruiting, 1 terminated, 1 unknown. 4 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Completed 1, Not yet recruiting 1, Terminated 1, Unknown 1 |
| Phase 1 | 1 | Unknown 1 |
Follow HER2 Positive: new trials by email Literature Review of HER2 Positive trials Research Report on HER2 Positive
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Dual EGFR/HER2 Blockade Combined With Irinotecan for the Treatment of HER2-Positive Metastatic Colorectal Cancer Trastuzumab +Cetuximab β+Irinotecan - HER2 Positive, Colorectal Cancer (CRC) | Phase 2 | Not yet recruiting | Sun Yat-sen University | 34 | 2025-07-11 | 2025-07-10 |
| Pyrotinib Maleate Tablets Combined With Albumin Paclitaxel and Trastuzumab for Her2-positive Breast Cancer Pyrotinib Maleate Tablets, Albumin Paclitaxel, Trastuzumab - Breast Cancer, HER2 Positive | Phase 1 / Phase 2 | Unknown | West China Hospital | 20 | 2019-11-01 | 2019-11-05 |
| A Study to Assess the Safety and Efficacy of the VEGFR-FGFR-PDGFR Inhibitor, Lucitanib, Given to Patients With Metastatic Breast Cancer Lucitanib - Breast Cancer, Metastatic Breast Cancer | Phase 2 | Terminated | Clovis Oncology, Inc. | 178 | 2014-09-09 | 2020-06-23 |
| Trastuzumab in a Neo-adjuvant Regimen for HER2+ Breast Cancer - the TRAIN Study paclitaxel, trastuzumab and carboplatin - Breast Cancer, HER2 Positive | Phase 2 | Completed | The Netherlands Cancer Institute | 111 | 2008-09-01 | 2012-05-11 |
Breast Neoplasms (3) · Colorectal Neoplasms (1)
Neoplasms (4) · Neoplasms by Site (4) · Breast Diseases (3) · Skin Diseases (3) · Skin and Connective Tissue Diseases (3) · Colonic Diseases (1) · Digestive System Diseases (1) · Digestive System Neoplasms (1) · Gastrointestinal Diseases (1) · Gastrointestinal Neoplasms (1) · Intestinal Diseases (1) · Intestinal Neoplasms (1) · Rectal Diseases (1)
Trastuzumab (2) · Carboplatin (1) · E-3810 (1) · Irinotecan (1) · Paclitaxel (1)
Clovis Oncology, Inc. (1) · Sun Yat-sen University (1) · The Netherlands Cancer Institute (1) · West China Hospital (1)
China (2) · Netherlands (1) · United States (1)
G S Sonke, MD (1) · Ting Luo, MD (1)
2008 (1)