Heart Decompensation: Clinical Trials

4 completed. 4 Phase 3.

By phase and status

Phase	Trials	Status
Phase 3	4	Completed 4

Follow Heart Decompensation: new trials by email Literature Review of Heart Decompensation trials Research Report on Heart Decompensation

Trials (filtered) newest first · largest first

All 4 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
A Study Testing the Effectiveness of Nesiritide in Patients With Acute Decompensated Heart Failure Nesiritide, Placebo - Heart Decompensation	Phase 3	Completed	Scios, Inc.	7141	2007-05-01	2013-03-08
An Open-label, One-arm, Study to Evaluate the Hemodynamic Changes and Safety of Nesiritide for Acute Decompensated Heart Failure Nesiritide - Heart Decompensation, Congestive Heart Failure	Phase 3	Completed	Xian-Janssen Pharmaceutical Ltd.	41	2006-10-01	2014-02-28
A Study to Develop Additional Safety and Clinical Experience With NATRECOR hBNP (Nesiritide) in the Treatment of Patients With Worsening Congestive Heart Failure Who Require Inpatient Intravenous Therapy With Medications That Influence the Tone and Caliber of Blood Vessels nesiritide - Heart Failure, Congestive, Heart Decompensation	Phase 3	Completed	Scios, Inc.	305	1997-01-01	2011-03-04
A Study of Two Doses of Intravenous NATRECOR hBNP (Nesiritide) in Patients With Worsening Congestive Heart Failure Who Have Difficulty Breathing at Rest nesiritide - Heart Failure, Congestive, Heart Decompensation	Phase 3	Completed	Scios, Inc.	127	1996-10-01	2011-06-10

Narrower conditions

Heart Failure (4)  ·  Cardiomyopathies (2)  ·  Dyspnea, Paroxysmal (2)  ·  Renal Insufficiency (2)  ·  Dyspnea (1)

Broader conditions

Cardiovascular Diseases (4)  ·  Heart Diseases (4)  ·  Pathological Conditions, Signs and Symptoms (3)  ·  Respiration Disorders (3)  ·  Respiratory Tract Diseases (3)  ·  Signs and Symptoms (3)  ·  Signs and Symptoms, Respiratory (3)  ·  Dyspnea (2)  ·  Female Urogenital Diseases (2)  ·  Female Urogenital Diseases and Pregnancy Complications (2)  ·  Kidney Diseases (2)  ·  Male Urogenital Diseases (2)  ·  Urogenital Diseases (2)  ·  Urologic Diseases (2)

Interventions

Natriuretic Peptide, Brain (4)

Sponsors

Scios, Inc. (3)  ·  Xian-Janssen Pharmaceutical Ltd. (1)

Countries

China (2)  ·  Argentina (1)  ·  Australia (1)  ·  Brazil (1)  ·  Bulgaria (1)  ·  Canada (1)  ·  Chile (1)  ·  Colombia (1)  ·  France (1)  ·  Germany (1)  ·  Greece (1)  ·  India (1)  ·  Israel (1)  ·  Lithuania (1)  ·  Malaysia (1)

Results publications

PMID 10400005, PMID 21732835, PMID 22497823, PMID 23032196, PMID 23770519, PMID 23899930, PMID 24054337, PMID 24464687, PMID 24622005, PMID 25074507, PMID 25281655, PMID 26304935, PMID 26988350, PMID 27623769, PMID 28641792, PMID 29431103, PMID 29781109, PMID 30354576, PMID 31606362, PMID 33775110, PMID 36314126, PMID 37725680