21 completed, 21 unknown, 8 recruiting, 7 terminated. 11 Not applicable, 10 Phase 2, 8 Phase 4, 6 Phase 3, 4 Phase 1.
Follow HBV: new trials by email Literature Review of HBV trials Research Report on HBV
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| HBV Reactivation in Immunocompromised Patients (REANT STUDY) Antiviral - HBV | Recruiting | Yaşar Bayındır, MD | 490 | 2026-03-09 | 2026-08-04 | |
| Prospective Cohort Study on PEG-IFN-α-2b in Improving Clinical Cure Rate of Pediatric Patients With Chronic Hepatitis B Peginterferon alfa-2b Injection - HBV, Chronic Hepatitis B Virus | Phase 4 | Not yet recruiting | Nanfang Hospital, Southern Medical University | 113 | 2026-01-01 | 2025-11-17 |
| Changes in Bile Acids and Microbiota in Patients With Hepatitis D Treated With Bulvertide HBV, HBV Coinfection | Recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 20 | 2025-09-24 | 2026-02-24 | |
| Clinical Performance Evaluation of MagIA IVD-MD Multiplex Testing (HIV/HBV/HCV/Syphilis) Multiplex Testing of HIV, HBV, HCV and Syphilis, HIV | Recruiting | MagIA Diagnostics | 2950 | 2025-07-29 | 2026-02-02 | |
| Real-world Study on Liver Cancer Risk in Chronic Hepatitis B Patients With Family History of Liver Cancer ETV,TDF,TAF,TMF combination with PEG IFNα-2b, ETV,TDF,TAF or TMF - HBV, HCC | Not yet recruiting | Peking University First Hospital | 1500 | 2025-06-01 | 2025-06-05 | |
| Non-interventional Study to Assess the Number of People With Untreated/Unknown HBV + HDV and HCV in South-East Austria HBV, HCV | Recruiting | Vanessa Stadlbauer-Koellner, MD | 100 | 2025-05-01 | 2026-06-18 | |
| A Real-World Study of Antiviral Therapy in Children With Chronic Hepatitis B Nucleos(t)ide Analogues, Interferon alfa, NAs combined with IFNα - HBV, Chronic Hepatitis b | Not yet recruiting | Beijing 302 Hospital | 2000 | 2025-05-01 | 2025-04-29 | |
| Phase 1b, Open-label Study of Tune-401 to Assess Safety, PK and PD in Adults With Chronic Hepatitis B Tune-401 - Chronic Hep B, Chronic Hepatitis b | Phase 1 | Recruiting | Tune Therapeutics, Inc. | 36 | 2024-11-29 | 2026-01-06 |
| Impact of Hepatitis B Immunoglobulins in Patients With Chronic Hepatitis B on Hepatocellular Carcinoma - a Proof of Concept Study Hepatect CP 50 I.E./ml infusion solution - Hepatocellular Carcinoma, HBV | Not applicable | Unknown | Medical University of Graz | 5 | 2024-11-01 | 2024-01-18 |
| Current Situation of Health Care in Women With HBV or HCV Infection HBV, HCV | Unknown | Ruijin Hospital | 2500 | 2024-09-01 | 2024-08-30 | |
| Antiviral Therapy in Infants With HBV Infection Lamivudine, Interferon - HBV | Phase 4 | Not yet recruiting | Beijing 302 Hospital | 60 | 2024-08-01 | 2024-07-23 |
| Effectiveness of a Self-health Assessment Mobile Application in Young-to-midlife Adults in Hong Kong Wellnuts app intervention, Web-based health resources - Diabetes Risk, CVD Risk | Not applicable | Recruiting | The University of Hong Kong | 574 | 2024-06-01 | 2026-07-22 |
| Rapid T-cell Analysis Test in Patients With Chronic HBV and HBV/HDV Disease HBV, HBV/HDV | Recruiting | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | 300 | 2024-04-15 | 2026-01-15 | |
| The TRIple Elimination Model Of Mother-to-child Transmission Program (TRI-MOM) TRI-MOM intervention - Hiv, Syphilis | Not applicable | Unknown | Institut de Recherche pour le Developpement | 2800 | 2024-03-18 | 2024-06-20 |
| Viral Immunity in Solid Organ Transplant Recipients: Monitoring Of The Response To Hepatitis B Booster Vaccination Tacrolimus, Belatacept - HBV, Kidney Transplantation | Unknown | University Hospital, Grenoble | 66 | 2024-03-15 | 2024-03-13 | |
| Predictive Value of HBV pgRNA on Long-term Outcomes in Hepatitis B Patients Treated With Antiviral Therapy nucleoside analogues or interferon - HBV, HCC | Not yet recruiting | Wen-hong Zhang | 5000 | 2023-12-01 | 2023-07-28 | |
| Study on the Treatment of Hepatitis B Virus(HBV) Infected Individuals With Peginterferon α-2b Combined With NA. Peg-IFNα-2b combined with NA, Nucleotide Analogues - HBV | Recruiting | Xiangya Hospital of Central South University | 400 | 2023-05-25 | 2024-12-24 | |
| The Efficacy and Safety of Rifaximin Treatment Rifaximin 200 mg, Standard Treatment without Rifaximin - Liver Failure, Acute on Chronic, Hepatic Encephalopathy | Early Phase 1 | Unknown | Sun Yat-sen University | 124 | 2023-03-09 | 2023-03-28 |
| Use of Blood Biomarkers for the Early Diagnosis of Hepatocellular Carcinoma (HCC) Biomarker dosage - HCC, Cirrhosis, Liver | Unknown | Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis | 60 | 2023-02-24 | 2024-04-08 | |
| Nivolumab/Ipilimumab and Chemotherapy Combination in Advanced NSCLC Patients With HIV, HBV, HCV and Long Covid Syndrome Nivolumab and Ipilimumab - NSCLC Stage IV, HIV | Phase 2 | Not yet recruiting | Universita di Verona | 105 | 2023-02-01 | 2022-10-28 |
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Hepatitis B (16) · Hepatitis B, Chronic (8) · Carcinoma, Hepatocellular (6) · Liver Cirrhosis (6) · Acquired Immunodeficiency Syndrome (5) · Non-alcoholic Fatty Liver Disease (5) · Hepatitis (3) · Hepatitis C (3) · Hepatitis, Alcoholic (3) · Acute-On-Chronic Liver Failure (2) · Coinfection (2) · Communicable Diseases (2) · Fibrosis (2) · HIV Infections (2) · Hepatitis D (2)
Digestive System Diseases (36) · Liver Diseases (33) · Infections (26) · Virus Diseases (24) · Blood-Borne Infections (23) · Hepatitis (22) · Pathological Conditions, Signs and Symptoms (22) · Communicable Diseases (21) · Hepatitis, Viral, Human (21) · Pathologic Processes (21) · DNA Virus Infections (19) · Hepadnaviridae Infections (19) · Disease Attributes (13) · Neoplasms (10) · RNA Virus Infections (10)
tenofovir alafenamide (8) · Tenofovir (5) · entecavir (4) · Interferons (2) · Lamivudine (2) · APG-1387 (1) · Abatacept (1) · Anti-HIV Agents (1) · Antiviral Agents (1) · Blood Specimen Collection (1) · Calcineurin Inhibitors (1) · Cohort Studies (1) · Elvitegravir, Cobicistat, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination (1) · Engerix-B (1) · Fendrix (1)
Gilead Sciences (4) · F-star Therapeutics, Inc. (3) · University of Alabama at Birmingham (3) · Beijing 302 Hospital (2) · Hopital Lariboisière (2) · Institute of Liver and Biliary Sciences, India (2) · Ruijin Hospital (2) · University Hospital, Grenoble (2) · West China Hospital (2) · Alnylam Pharmaceuticals (1) · Ascentage Pharma Group Inc. (1) · Assistance Publique - Hôpitaux de Paris (1) · Aucta Pharmaceuticals, Inc (1) · Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis (1) · Beckman Coulter, Inc. (1)
China (19) · France (8) · Italy (6) · United States (5) · Canada (4) · Hong Kong (4) · South Korea (4) · Taiwan (4) · Australia (3) · India (3) · New Zealand (3) · United Kingdom (3) · Zambia (3) · Singapore (2) · Argentina (1)
Michael J Vinikoor, MD (3) · Don Mitchell (2) · Benedetta Massetto, M.D. (1) · Cheng-Chung Wei, MD (1) · Ching-Pin Lin, MD (1) · Dr Ajeet Singh Bhadoria, MD (1) · Endrit Shahini, MD (1) · Francesca Romana Ponziani (1) · Fubing Wang, Doctor (1) · Fusheng Wang (1) · Guiqiang Wang, Ph.D (1)
PMID 37771546, PMID 10898704, PMID 20335583, PMID 21157444, PMID 22233350, PMID 22913681, PMID 23993913, PMID 25819304, PMID 26084406, PMID 26503488, PMID 26709883, PMID 27512927, PMID 27879486, PMID 28802168, PMID 28902040, PMID 28994123, PMID 29193547, PMID 30244215, PMID 31172417, PMID 31988585, PMID 32004593, PMID 32781201, PMID 33385299, PMID 33421158, PMID 34006193, PMID 35220659, PMID 37290591, PMID 38838460, PMID 41649980, PMID 42767612
K01TW009998 (1), P30CA016672 (1), R21CA167202 (1)