5 recruiting, 1 active not recruiting, 1 completed, 1 unknown. 3 Phase 1, 3 Phase 2, 1 Not applicable, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Recruiting 3 |
| Phase 2 | 3 | Recruiting 2, Completed 1 |
| Not applicable | 1 | Unknown 1 |
| Phase 4 | 1 | Recruiting 1 |
Follow Esthesioneuroblastoma: new trials by email Literature Review of Esthesioneuroblastoma trials Research Report on Esthesioneuroblastoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Radiation Combined With BIspecific T-Cell Engager in DLL3 Expressing Tumors Tarlatamab, Concurrent Radiation Therapy, Sequential Radiation therapy - Melanoma, Medullary Thyroid Cancer | Phase 1 / Phase 2 | Recruiting | University of Arizona | 30 | 2025-09-08 | 2026-10-06 |
| [212Pb]VMT-Alpha-NET in Metastatic or Inoperable Somatostatin-Receptor Positive Gastrointestinal Neuroendocrine Tumors, Pheochromocytoma/Paragangliomas, Small Cell Lung, Renal Cell, and Head and Neck Cancers [212Pb]VMT-alpha-NET, [203Pb]VMT-alpha-NET, 68Ga-DOTATATE - Sinonasal Neuroendocrine Carcinoma, Nasopharyngeal Carcinoma | Phase 1 | Recruiting | National Cancer Institute (NCI) | 120 | 2025-08-19 | 2026-10-06 |
| Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed). Olaparib; 177Lu-DOTATATE - Solid Tumor Cancer, Medulloblastoma | Phase 1 / Phase 2 | Recruiting | Fundación de investigación HM | 25 | 2024-09-20 | 2026-06-04 |
| Phase 2 Study of Bintrafusp Alfa in Recurrent/Metastatic Olfactory Neuroblastoma (BARON). Bintrafusp alfa/M7824, Ibuprofen, PET scan - Olfactory Neuroblastoma, Esthesioneuroblastoma | Phase 2 | Completed | National Cancer Institute (NCI) | 11 | 2022-06-21 | 2025-08-08 |
| A Natural History Study of Children and Adults With Olfactory Neuroblastoma Olfactory Neuroblastoma, Esthesioneuroblastoma | Recruiting | National Cancer Institute (NCI) | 525 | 2022-06-02 | 2026-10-16 | |
| 68-Ga DOTATATE PET/MRI in the Diagnosis and Management of Somatostatin Receptor Positive CNS Tumors. Ga68-DOTATATE-PET/MRI - CNS Tumors, Meningioma | Phase 4 | Recruiting | Weill Medical College of Cornell University | 200 | 2019-09-04 | 2025-11-21 |
| Long-Term Longitudinal QoL in Patients Undergoing EEA Pituitary Tumor, Meningioma | Active not recruiting | Ohio State University | 400 | 2019-07-16 | 2026-05-20 | |
| Intensity-Modulated or Proton Radiation Therapy for Sinonasal Malignancy Proton radiation therapy, Intensity-modulated radiotherapy - Adenoid Cystic Carcinoma, Squamous Cell Carcinoma | Not applicable | Unknown | Massachusetts General Hospital | 45 | 2011-07-12 | 2023-09-21 |
Esthesioneuroblastoma, Olfactory (8) · Meningioma (3) · Paraganglioma (3) · Glioblastoma (2) · Medulloblastoma (2) · Melanoma (2) · Pheochromocytoma (2) · Pituitary Neoplasms (2) · Sinonasal undifferentiated carcinoma (2) · Adrenal Cortex Neoplasms (1) · Adrenal Gland Neoplasms (1) · Carcinoma, Adenoid Cystic (1) · Carcinoma, Medullary (1) · Carcinoma, Merkel Cell (1) · Carcinoma, Mucoepidermoid (1)
Cranial Nerve Diseases (8) · Neoplasms (8) · Neoplasms by Histologic Type (8) · Neoplasms, Germ Cell and Embryonal (8) · Neoplasms, Glandular and Epithelial (8) · Neoplasms, Nerve Tissue (8) · Neoplasms, Neuroepithelial (8) · Nervous System Diseases (8) · Neuroectodermal Tumors (8) · Neuroectodermal Tumors, Primitive (8) · Neuroectodermal Tumors, Primitive, Peripheral (8) · Olfactory Nerve Diseases (8) · Neoplasms by Site (7) · Neuroblastoma (7) · Endocrine Gland Neoplasms (4)
Electrocardiography (1) · Ibuprofen (1) · Positron-Emission Tomography (1) · Protons (1) · Radionuclide Imaging (1) · Radiotherapy, Intensity-Modulated (1) · Tomography, X-Ray Computed (1) · gallium Ga 68 dotatate (1) · lutetium Lu 177 dotatate (1) · olaparib (1)
National Cancer Institute (NCI) (3) · Fundación de investigación HM (1) · Massachusetts General Hospital (1) · Ohio State University (1) · University of Arizona (1) · Weill Medical College of Cornell University (1)
United States (7) · Spain (1)
Charalampos Floudas, M.D. (2) · Annie W Chan, MD (1) · Charles Hsu, MD (1) · Frank I Lin, M.D. (1) · Jana Ivanidze, MD/Ph.D (1) · Kyle Wu, MD (1) · Marta Osuna Marco, PhD (1) · Ricklie Julian, MD (1)
PMID 35275019, PMID 35661809, PMID 38553990, PMID 39500789, PMID 42307670
P01CA021239 (1)