5 not yet recruiting, 2 recruiting, 1 active not recruiting. 1 Early Phase 1, 1 Not applicable, 1 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Early Phase 1 | 1 | Not yet recruiting 1 |
| Not applicable | 1 | Recruiting 1 |
| Phase 2 | 1 | Not yet recruiting 1 |
| Phase 4 | 1 | Not yet recruiting 1 |
Follow Endometrial Intraepithelial Neoplasia: new trials by email Literature Review of Endometrial Intraepithelial Neoplasia trials Research Report on Endometrial Intraepithelial Neoplasia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Tirzepatide in Women With Obesity and Endometrial Intra-epithelial Neoplasia or Grade 1 Endometrial Cancer Tirzepatide - Endometrial Cancer, Endometrial Intraepithelial Neoplasia | Phase 2 | Not yet recruiting | UNC Lineberger Comprehensive Cancer Center | 40 | 2027-01-01 | 2026-09-28 |
| SHAPE-ENDO: Pilot Randomized Trial of Multimodal Pre-Surgical Optimization Versus Standard Surgery in Patients With Obesity and Early-Stage Endometrial Cancer GLP-1 Receptor Agonist, Levonorgestrel IUD (Lng-IUD), Oral Progestins - Endometrial Cancer, Endometrial Cancer Stage I | Phase 4 | Not yet recruiting | Hospital Universitari de Bellvitge | 80 | 2027-01-01 | 2026-06-10 |
| Tirzepatide and Levonorgestrel IUD Therapy for EIN and Early-Stage Endometrial Cancer Tirzepatide - Grade 1 Endometrial Endometrioid Carcinoma, Endometrial Intraepithelial Neoplasia | Early Phase 1 | Not yet recruiting | Milton S. Hershey Medical Center | 15 | 2026-11-01 | 2026-09-10 |
| Measurement of Urinary Hormones in Patients With Abnormal Uterine Bleeding to Study Uterine Cancer Progression Uterine Bleeding, Uterine Cancer | Not yet recruiting | University of British Columbia | 50 | 2026-05-01 | 2026-05-12 | |
| Endometrial Cancer Vaginal Fluid Specimen Collection Study Abnormal Uterine Bleeding (AUB), Endometrial Cancer | Active not recruiting | Exact Sciences Corporation | 4200 | 2026-03-10 | 2026-10-05 | |
| A Multi-center Prospective Study on the Oncological and Reproductive Outcomes and Quality of Life in Young Woman After Fertility-sparing Treatment of Endometrial Cancer and Endometrial Intraepithelial Hyperplasia Endometrial Cancer, Endometrial Intraepithelial Neoplasia | Not yet recruiting | Region Stockholm | 100 | 2025-01-15 | 2024-12-20 | |
| InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer Samples - Cancer Risk, Cancer Predisposition Syndrome | Recruiting | Dana-Farber Cancer Institute | 5000 | 2023-04-25 | 2026-08-17 | |
| Concurrent Laparoscopic Hysterectomy and Weight Loss Surgery in Obese Patients With Endometrial Carcinoma or Endometrial Intraepithelial Neoplasia CONCURRENT LAPAROSCOPIC HYSTERECTOMY AND WEIGHT LOSS SURGERY-Referral - Endometrial Carcinoma, Obesity | Not applicable | Recruiting | Dana-Farber Cancer Institute | 30 | 2021-08-01 | 2026-08-31 |
Endometrial Hyperplasia (8) · Endometrial Neoplasms (6) · Obesity (3) · Metrorrhagia (2) · Barrett Esophagus (1) · Carcinoma in Situ (1) · Carcinoma, Lobular (1) · Fibrosis (1) · Giant Cell Tumors (1) · Hematologic Neoplasms (1) · Hyperplasia (1) · Lung Neoplasms (1) · Neoplasms (1) · Nevus, Epithelioid and Spindle Cell (1) · Non-alcoholic Fatty Liver Disease (1)
Female Urogenital Diseases (8) · Female Urogenital Diseases and Pregnancy Complications (8) · Genital Diseases (8) · Genital Diseases, Female (8) · Urogenital Diseases (8) · Uterine Diseases (8) · Neoplasms by Site (7) · Genital Neoplasms, Female (6) · Neoplasms (6) · Pathological Conditions, Signs and Symptoms (6) · Urogenital Neoplasms (6) · Uterine Neoplasms (5) · Pathologic Processes (4) · Body Weight (3) · Nutrition Disorders (3)
Tirzepatide (2) · Estrogen Replacement Therapy (1) · Hysterectomy (1) · Hysteroscopy (1) · Magnetic Resonance Spectroscopy (1) · Medroxyprogesterone Acetate (1) · Megestrol Acetate (1) · Nutrition Assessment (1) · Progestins (1) · Resistance Training (1) · Sampling Studies (1) · semaglutide (1)
Dana-Farber Cancer Institute (2) · Exact Sciences Corporation (1) · Hospital Universitari de Bellvitge (1) · Milton S. Hershey Medical Center (1) · Region Stockholm (1) · UNC Lineberger Comprehensive Cancer Center (1) · University of British Columbia (1)
United States (5) · Canada (1)
Colleen Feltmate, MD (1) · Jorge Garcia Fernandez (1) · Lola Marti (1) · Sapna Syngal, MD (1) · Shaina Bruce, MD (1) · Victoria Bae-Jump (1)
U01CA281026 (1)