8 completed, 5 not yet recruiting, 2 recruiting, 1 active not recruiting. 8 Not applicable, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 8 | Completed 4, Not yet recruiting 4 |
| Phase 2 | 3 | Completed 2, Active not recruiting 1 |
Follow Early Childhood Caries (ECC): new trials by email Literature Review of Early Childhood Caries (ECC) trials Research Report on Early Childhood Caries (ECC)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| This Feasibility Study Will Evaluate the Study Protocols for Treatment and Follow-up Controls of Primary Molars With Caries in Children Treated With Stainless Steel Crowns or Conventional Fillings. Treatment Success and Potential Failures Will be Followed at 3, 6 and 12 Months Post Treatment. Stainless steel crowns, Conventional fillings - Dental Caries, Early Childhood Caries (ECC) | Not applicable | Not yet recruiting | Marie Norman | 100 | 2026-10-05 | 2026-10-20 |
| WhatsApp Messages to Improve Mothers' Oral Health Knowledge and Children's Toothbrushing Standardized Face-to-Face Oral Health Education, WhatsApp-Based Oral Health Messages - Oral Health, Dental Caries | Not applicable | Not yet recruiting | King Abdulaziz University | 106 | 2026-08-30 | 2026-08-18 |
| Zirconia Crowns Versus Extraction of Primary Anterior Teeth Zirconia Crown, Extraction - Early Childhood Caries (ECC) | Not applicable | Not yet recruiting | Passant Nagy | 60 | 2026-07-18 | 2026-07-22 |
| Midwives' Perspectives on Oral Health in Pregnancy and Early Childhood: A Cross-Sectional Online Survey Oral Health in Pregnancy and Early Childhood, Early Childhood Caries (ECC) | Not yet recruiting | University Medical Center Goettingen | 200 | 2026-05-01 | 2026-05-07 | |
| Efficacy of Silver Diamine Fluoride Versus Nano-Silver Fluoride in Arresting Active Dentin Caries in Primary Teeth in Young Children Nano-Silver Fluoride, Silver Diamine Fluoride - Early Childhood Caries (ECC), Active Dentin Caries in Primary Molars | Not applicable | Not yet recruiting | October University for Modern Sciences and Arts | 60 | 2026-01-30 | 2026-02-02 |
| Preventing Early Childhood Caries With a Silver Diamine Fluoride Gel Silver diamine fluoride gel, Sodium Fluoride varnish - Early Childhood Caries (ECC) | Phase 2 | Active not recruiting | The University of Hong Kong | 1500 | 2026-01-01 | 2026-03-06 |
| Effect Of Three Remineralizing Agents On Early Childhood Caries Silver Diamine Fluoride (SDF, 38%), Sodium Fluoride with CPP-ACP, Acidulated phospahate fluoride gel 1.23% - Early Childhood Caries (ECC), Dental Caries | Phase 2 | Completed | University of Jazan | 90 | 2025-11-01 | 2026-09-10 |
| Caries Risk in Children Treated Under General Anesthesia for Early Childhood Caries Caries Risk Assesment - Early Childhood Caries (ECC) | Recruiting | Aydin Adnan Menderes University | 44 | 2025-05-07 | 2026-01-09 | |
| Assessment of Oral Health-Related Quality of Life in Preschool-Aged Children in Alto Alentejo Oral Health Related Quality of Life (OHRQoL), Early Childhood Caries (ECC) | Completed | University of Lisbon | 454 | 2025-04-11 | 2026-06-16 | |
| Analysis of Salivary Proteins in Young Children as an Device to Improve Caries Risk Assessment Early Childhood Caries (ECC) | Recruiting | Karolinska Institutet | 100 | 2025-04-04 | 2026-08-05 | |
| Aesthetic and Functional Evaluation of a Universal One-Shade Composite in Primary Maxillary Incisors Tokuyama Palfique Omnichroma composite restoration, 3M Filtek Z350 composite restoration - Early Childhood Caries (ECC) | Not applicable | Completed | Goa Dental College | 30 | 2025-03-01 | 2026-07-21 |
| Oral Health Awareness Among Egyptian Population Early Childhood Caries (ECC), Oral Health Behavior Change | Completed | Cairo University | 57 | 2025-01-01 | 2025-11-25 | |
| Evaluation of Silver Diamine Fluoride, Sodium Fluoride With Casein Phosphopeptide-Amorphous Calcium Phosphate(MI Varnish) and Dycal to Arrest Caries When Used in Indirect Pulp Capping Procedures in Children Silver Diamine Fluoride (SDF, 38%) gel, Sodium Fluoride with CPP-ACP (MI varnish), Calcium Hydroxide (CH) - Early Childhood Caries (ECC), Color Stability of Restoration | Phase 2 | Completed | University of Jazan | 90 | 2024-05-06 | 2026-10-26 |
| Goal Attainment-Based Parent Education for ECC Prevention Structured Parent Education - Early Childhood Caries (ECC) | Not applicable | Completed | Karadeniz Technical University | 100 | 2024-02-01 | 2026-03-10 |
| Evaluating the Effect of Xylitol Wipes on Cariogenic Bacteria in Infants and Toddlers Xylitol Dental Wipes - Early Childhood Caries (ECC), Dental Caries Prevention | Not applicable | Completed | Alexandria University | 20 | 2024-01-01 | 2025-11-24 |
| Effects of Calcium-Containing Oral Sprays on Fluorescence-Detectable Plaque Area in Children oral spray - Dental Caries Tooth Demineralization, Early Childhood Caries (ECC) | Not applicable | Completed | Tri-Service General Hospital (TSGH) | 15 | 2023-06-11 | 2026-08-21 |
| Early Childhood Caries and Health Professionals' Perception: a Qualitative Research Protocol to Assess Oral Health Stigma Exploring health professionals' perceptions of patients with ECC using semi-structured interviews - Early Childhood Caries (ECC) | Unknown | Hospices Civils de Lyon | 30 | 2022-06-01 | 2022-03-17 |
Dental Caries (5) · Behavior (1) · Gingivitis (1) · Health Behavior (1) · Malocclusion (1) · Social Stigma (1)
Stomatognathic Diseases (6) · Tooth Diseases (6) · Tooth Demineralization (5) · Behavior (2) · Gingival Diseases (1) · Infections (1) · Mouth Diseases (1) · Periodontal Diseases (1) · Social Behavior (1)
silver diamine fluoride (3) · Sodium Fluoride (2) · casein phosphopeptide-amorphous calcium phosphate nanocomplex (2) · Bifluorid 12 (1) · Calcium Hydroxide (1) · Gels (1) · Oral Sprays (1)
University of Jazan (2) · Alexandria University (1) · Aydin Adnan Menderes University (1) · Cairo University (1) · Goa Dental College (1) · Hospices Civils de Lyon (1) · Karadeniz Technical University (1) · Karolinska Institutet (1) · King Abdulaziz University (1) · Marie Norman (1) · October University for Modern Sciences and Arts (1) · Passant Nagy (1) · The University of Hong Kong (1) · Tri-Service General Hospital (TSGH) (1) · University Medical Center Goettingen (1)
Egypt (3) · Saudi Arabia (2) · Sweden (2) · Turkey (Türkiye) (2) · China (1) · France (1) · India (1) · Portugal (1) · Taiwan (1)
Aliaa A Hamouda, BDS,MSc,PhD (1) · Chun Hung Chu (1) · Georgios Tsilingaridis, Vice Dean, Associate professor (1) · Laila M El-Habashy, BDS,MSc,PhD (1) · Omar A El Meligy, BDS,MSc,PhD (1) · Ruhi Sanvordekar, MDS (1) · Serpil Boran, MSc (1)
PMID 16842502, PMID 17867402, PMID 19508271, PMID 19717413, PMID 32025425, PMID 36455999, PMID 40731400, PMID 41888802, PMID 42816839