2 active not recruiting, 2 completed, 1 not yet recruiting, 1 recruiting. 2 Phase 1, 2 Phase 2, 1 Early Phase 1, 1 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 2 | Active not recruiting 1, Terminated 1 |
| Phase 2 | 2 | Completed 1, Terminated 1 |
| Early Phase 1 | 1 | Recruiting 1 |
| Not applicable | 1 | Completed 1 |
Follow Donor: new trials by email Literature Review of Donor trials Research Report on Donor
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cousin vs. Sibling Donors in Haplo-HSCT Hematopoietic Malignancies, Haploidentical Hematopoietic Stem Cell Transplantation | Not yet recruiting | The First Affiliated Hospital of Soochow University | 1000 | 2026-08-01 | 2026-06-23 | |
| External Oblique Intercostal Plane Block for Liver Transplantation Donors Subcostal transversus abdominis plane block, External oblique intercostal plane block - Liver Transplantation, Donor | Not applicable | Completed | Istinye University | 64 | 2023-05-08 | 2024-03-19 |
| Donor Virus-Specific CMV or AdV CTL to Treat CMV or AdV Reactivation or Disease After Solid Organ or HCT Allogeneic Cytomegalovirus-Specific Cytotoxic T lymphocytes, Allogeneic Adenovirus-specific Cytotoxic T Lymphocytes - Allogeneic Hematopoietic Stem Cell Transplantation Recipient, Cytomegalovirus | Early Phase 1 | Recruiting | Sumithira Vasu | 20 | 2020-11-07 | 2026-09-24 |
| Blood Samples to Identify Biomarkers in Patients Treated With Cyclophosphamide After Donor Stem Cell Transplant Biospecimen Collection-Blood, Biospecimen Collection-Stool - Allogeneic Hematopoietic Stem Cell Transplant Recipient, Donor | Active not recruiting | City of Hope Medical Center | 72 | 2018-11-13 | 2026-07-28 | |
| CMV-MVA Triplex Vaccination of Stem Cell Donors in Preventing CMV Viremia in Participants With Allogeneic Transplant Multi-peptide CMV-Modified Vaccinia Ankara Vaccine - Accelerated Phase CML, BCR-ABL1 Positive, Acute Lymphoblastic Leukemia in Remission | Phase 1 | Active not recruiting | City of Hope Medical Center | 34 | 2018-08-20 | 2026-09-28 |
| Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors in Preventing GVHD Allogeneic Hematopoietic Stem Cell Transplantation, Cyclophosphamide, Fludarabine Phosphate - Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Biphenotypic Leukemia | Phase 2 | Completed | Fred Hutchinson Cancer Center | 84 | 2015-03-23 | 2026-06-01 |
| Laboratory-Treated T Cells in Treating Patients With High-Risk Relapsed Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelogenous Leukemia Previously Treated With Donor Stem Cell Transplant Aldesleukin, Cyclophosphamide, Fludarabine Phosphate - Recurrent Adult Acute Myeloid Leukemia, Recurrent Childhood Acute Myeloid Leukemia | Phase 1 / Phase 2 | Terminated | Fred Hutchinson Cancer Center | 47 | 2012-12-06 | 2022-07-14 |
Hematologic Neoplasms (2) · Leukemia, Myeloid, Accelerated Phase (2) · Leukemia, Myeloid, Acute (2) · Adenoviridae Infections (1) · Anemia, Refractory, with Excess of Blasts (1) · Blast Crisis (1) · Blastic Plasmacytoid Dendritic Cell Neoplasm (1) · Hodgkin Disease (1) · Leukemia, Biphenotypic, Acute (1) · Leukemia, Lymphocytic, Chronic, B-Cell (1) · Leukemia, Myelogenous, Chronic, BCR-ABL Positive (1) · Leukemia, Myeloid, Chronic-Phase (1) · Lymphoma, Non-Hodgkin (1) · Myelodysplastic Syndromes (1) · Myelodysplastic-Myeloproliferative Diseases (1)
Hematologic Diseases (4) · Hemic and Lymphatic Diseases (4) · Neoplasms (4) · Leukemia (3) · Leukemia, Myeloid (3) · Neoplasms by Histologic Type (3) · Neoplasms by Site (3) · Pathologic Processes (3) · Pathological Conditions, Signs and Symptoms (3) · Bone Marrow Diseases (2) · Chronic Disease (2) · Disease Attributes (2) · Immune System Diseases (2) · Immunoproliferative Disorders (2) · Leukemia, Lymphoid (2)
Cyclophosphamide (2) · fludarabine phosphate (2) · Methotrexate (1) · Mycophenolic Acid (1) · Peripheral Blood Stem Cell Transplantation (1) · Tacrolimus (1) · Thiotepa (1) · Whole-Body Irradiation (1) · aldesleukin (1) · merphos (1)
City of Hope Medical Center (2) · Fred Hutchinson Cancer Center (2) · Istinye University (1) · Sumithira Vasu (1) · The First Affiliated Hospital of Soochow University (1)
United States (5) · China (1) · Turkey (Türkiye) (1)
Aude Chapuis (1) · Jeannine S McCune (1) · Marie Bleakley (1) · Ryotaro Nakamura, MD (1) · Sumithira Vasu, MBBS (1) · Taylan Sahin, M.D. (1) · Yang Xu (1)
PMID 29042364, PMID 31235963, PMID 35007144, PMID 36594185, PMID 40840080
P01CA018029 (2), R01HL121568 (1), U01CA239373 (1)