External Oblique Intercostal Plane Block for Postoperative Analgesia in Living Liver Donors
| Registry | NCT05890079 |
|---|---|
| Status | Completed |
| Phase | Not applicable |
| Study type | Interventional; randomized, parallel, masking: double, other |
| Enrollment | 64 (Actual) |
| Sponsor | Istinye University (Other) |
| Conditions | Liver Transplantation, Donor, Postoperative Pain |
| Interventions | Subcostal transversus abdominis plane block, External oblique intercostal plane block (Other) |
| Dates | start 2023-05-08, primary completion 2023-12-14, completion 2024-01-17, first posted 2023-06-06, last updated 2024-03-19 |
| Locations | 1 site in Turkey (Türkiye) |
Related Papers Related Patents Related Grants Related Experts
All trials for Liver Transplantation All trials for Donor All trials of Subcostal transversus abdominis plane block All trials of External oblique intercostal plane block
Postoperative pain management is one of the important factors to improve rehabilitation and enhance recovery. External oblique intercostal plane block may be used for abdominal wall analgesia to provide effective analgesia for abdominal surgery. The aim of this study is to investigate the postoperative analgesic efficacy of external oblique intercostal plane block and subcostal transversus abdominis plane block in living liver donors.
Researchers will compare the external oblique intercostal plane block group with subcostal transversus abdominis plane block to see if the external oblique intercostal plane block is effective for postoperative analgesia in living liver donors.
Patients scheduled for living donor hepatectomy will be separated into 2 groups: Subcostal Transversus Abdominis Plane Block Group and External Oblique Intercostal Plane Block Group. Patients in Subcostal Transversus Abdominis Plane Block will be performed subcostal transversus plane block at the end of the surgery and after skin closure and received patient controlled analgesia with morphine for postoperative analgesia. Patients in External Oblique Intercostal Plane Block Group will be performed bilateral External Oblique Intercostal Plane Block at the end of the surgery and after skin closure and received patient controlled analgesia with morphine for postoperative analgesia. Morphine consumption for first postoperative 24 hours, visual analog scale scores, time to need for first rescue analgesia, amount of rescue analgesic drug, incidence of postoperative nausea and vomiting will be recorded.
| Arm | Type | Interventions | Description |
|---|---|---|---|
| Subcostal transversus abdominis plane block group | Active comparator | Other: Subcostal transversus abdominis plane block | The patients in subcostal transversus abdominis plane block group will be received subcostal transversus abdominis plane block and patient controlled analgesia with morphine for postoperative analgesia |
| External oblique intercostal plane block group | Active comparator | Other: External oblique intercostal plane block | The patients in External oblique intercostal plane block group will be received external oblique intercostal plane block and patient controlled analgesia with morphine for postoperative analgesia |
Sex: All, ages: 18 Years to 75 Years
Inclusion Criteria: * Age between 18 and 75 years * Patients with American Society of Anesthesiology (ASA) physical status I-II * Patients scheduled for a living donor hepatectomy Exclusion Criteria: * Allergy to local anesthetics * Coagulopathy * Skin infection at the block area * Advanced renal failure * Chronic pain syndromes * Alcohol or drug abuse * Psychiatric disorders
| Facility | City | Country | Status |
|---|---|---|---|
| Istinye University Hospital | Istanbul | Turkey (Türkiye) |