Cushing Disease: Clinical Trials

4 trials for Cushing Disease, newest first

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4 completed. 4 Phase 2, 1 Phase 1.

By phase and status

PhaseTrialsStatus
Phase 24Completed 4
Phase 11Completed 1

Follow Cushing Disease: new trials by email Literature Review of Cushing Disease trials Research Report on Cushing Disease

Trials (filtered) newest first · largest first

All 4 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
A Study to Evaluate the Safety and PK of CRN04894 for the Treatment of Cushing's Syndrome
atumelnant - Cushing Syndrome, Cushing Disease
Phase 1 / Phase 2CompletedCrinetics Pharmaceuticals Inc.192023-10-122026-10-14
Multicenter Study of Seliciclib (R-roscovitine) for Cushing Disease
Seliciclib - Cushing Disease
Phase 2CompletedCedars-Sinai Medical Center52018-11-022026-10-16
Safety and Efficacy of LCI699 in Cushing's Disease Patients
LCI699 - Cushings Disease, Cushing Disease
Phase 2CompletedNovartis Pharmaceuticals312011-03-232021-01-22
Extension Study to Assess the Safety and Efficacy of Pasireotide in Participants With Cushing's Disease
Pasireotide - Cushing Disease
Phase 2CompletedNovartis Pharmaceuticals192004-08-132021-06-02

Narrower conditions

Pituitary ACTH Hypersecretion (4)  ·  ACTH Syndrome, Ectopic (1)  ·  Adrenocortical Hyperfunction (1)  ·  Cushing Syndrome (1)  ·  Pituitary Diseases (1)

Broader conditions

Brain Diseases (4)  ·  Central Nervous System Diseases (4)  ·  Endocrine System Diseases (4)  ·  Hyperpituitarism (4)  ·  Hypothalamic Diseases (4)  ·  Nervous System Diseases (4)  ·  Pituitary Diseases (3)  ·  Adrenal Gland Diseases (2)  ·  Adrenocortical Hyperfunction (1)  ·  Neoplasms (1)  ·  Paraneoplastic Endocrine Syndromes (1)  ·  Paraneoplastic Syndromes (1)

Interventions

Osilodrostat (1)  ·  Roscovitine (1)  ·  pasireotide (1)

Sponsors

Novartis Pharmaceuticals (2)  ·  Cedars-Sinai Medical Center (1)  ·  Crinetics Pharmaceuticals Inc. (1)

Countries

United States (4)  ·  France (2)  ·  Italy (2)  ·  Germany (1)  ·  Japan (1)  ·  United Kingdom (1)

Top investigators

Ning-Ai Liu, MD, PhD (1)  ·  Shlomo Melmed, MD (1)

Results publications

PMID 23943009, PMID 24423285, PMID 41052284

NIH funding

2004 (1)