3 unknown, 1 recruiting, 1 terminated. 5 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 5 | Unknown 3, Recruiting 1, Terminated 1 |
Follow Costello Syndrome: new trials by email Literature Review of Costello Syndrome trials Research Report on Costello Syndrome
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Acceptance and Commitment Therapy for Caregivers of Children With a RASopathy: An Internal Pilot Feasibility Study and Follow-up Randomized Controlled Trial Waitlist, ACT Intervention - Neurofibromatosis 1, Noonan Syndrome | Not applicable | Recruiting | National Cancer Institute (NCI) | 70 | 2024-01-10 | 2026-10-16 |
| Solid Tumors in RASopathies Molecular characterization of solid tumor in RASopathies - RASopathy, Costello Syndrome | Not applicable | Unknown | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 100 | 2021-10-12 | 2024-04-04 |
| Effect of RAS/MAPK Pathway Hyperactivation on Growth' and Bone' Profile of the RASopathies Diagnostic test - RASopathy, Costello Syndrome | Not applicable | Unknown | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 120 | 2021-04-22 | 2024-03-26 |
| Prevalence and Characterization of Pain in RASopathies Characterization of pain - RASopathy, Costello Syndrome | Not applicable | Unknown | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 150 | 2021-01-27 | 2025-03-21 |
| Pathophysiology Analysis of "Costello Syndrome" on Cellular Models Biopsy - Costello Syndrome | Not applicable | Terminated | University Hospital, Bordeaux | 9 | 2015-06-01 | 2026-06-08 |
Cardiofaciocutaneous syndrome (4) · Noonan Syndrome (4) · Genetic Diseases, Inborn (1) · Legius syndrome (1) · Neurofibromatosis 1 (1)
Abnormalities, Multiple (5) · Congenital Abnormalities (5) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (5) · Craniofacial Abnormalities (5) · Musculoskeletal Abnormalities (5) · Musculoskeletal Diseases (5) · Cardiovascular Abnormalities (4) · Cardiovascular Diseases (4) · Connective Tissue Diseases (4) · Genetic Diseases, Inborn (4) · Heart Defects, Congenital (4) · Heart Diseases (4) · Skin and Connective Tissue Diseases (4) · Heredodegenerative Disorders, Nervous System (1) · Neoplasms (1)
Biopsy (1) · Diagnostic Tests, Routine (1) · Waiting Lists (1)
Fondazione Policlinico Universitario Agostino Gemelli IRCCS (3) · National Cancer Institute (NCI) (1) · University Hospital, Bordeaux (1)
Italy (3) · France (1) · United States (1)
Chiara Leoni, MD, PhD (3) · Staci M Peron, Ph.D. (1)