3 recruiting, 1 completed, 1 not yet recruiting. 1 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 1 | Recruiting 1 |
Follow Legius syndrome: new trials by email Literature Review of Legius syndrome trials Research Report on Legius syndrome
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Genetics Branch Eligibility Screening Survey Melanoma, Li-Fraumeni Syndrome | Not yet recruiting | National Cancer Institute (NCI) | 1000 | 2026-10-29 | 2026-10-26 | |
| Acceptance and Commitment Therapy for Caregivers of Children With a RASopathy: An Internal Pilot Feasibility Study and Follow-up Randomized Controlled Trial Waitlist, ACT Intervention - Neurofibromatosis 1, Noonan Syndrome | Not applicable | Recruiting | National Cancer Institute (NCI) | 70 | 2024-01-10 | 2026-10-16 |
| Clinical, Genetic, and Epidemiologic Study of Children and Adults With RASopathies Costello Syndrome, Noonan Syndrome | Recruiting | National Cancer Institute (NCI) | 500 | 2022-04-25 | 2026-10-02 | |
| RASopathy Biorepository RAS Mutation, Neurofibromatosis 1 | Recruiting | Children's Hospital Medical Center, Cincinnati | 1000 | 2017-06-27 | 2025-12-18 | |
| Study of Disease Severity in Adults With Neurofibromatosis Type 1 (NF1) Neurofibromatosis Type 1, Legius Syndrome | Completed | National Cancer Institute (NCI) | 313 | 2005-07-27 | 2026-08-31 |
Cardiofaciocutaneous syndrome (4) · Costello Syndrome (4) · Neurofibromatosis 1 (3) · Noonan Syndrome (3) · Capillary Malformation-Arteriovenous Malformation (1) · Chordoma (1) · Congenital Bone Marrow Failure Syndromes (1) · Fanconi Anemia (1) · Genetic Diseases, Inborn (1) · LEOPARD Syndrome (1) · Li-Fraumeni Syndrome (1) · Melanoma (1) · Melanoma, Cutaneous Malignant (1) · Neoplasms (1)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (5) · Abnormalities, Multiple (4) · Congenital Abnormalities (4) · Craniofacial Abnormalities (4) · Genetic Diseases, Inborn (4) · Musculoskeletal Abnormalities (4) · Musculoskeletal Diseases (4) · Neoplasms by Histologic Type (4) · Neoplasms, Nerve Tissue (4) · Neoplastic Syndromes, Hereditary (4) · Skin and Connective Tissue Diseases (4) · Cardiovascular Abnormalities (3) · Cardiovascular Diseases (3) · Connective Tissue Diseases (3) · Heart Defects, Congenital (3)
Waiting Lists (1)
National Cancer Institute (NCI) (4) · Children's Hospital Medical Center, Cincinnati (1)
United States (5)
Douglas R Stewart, M.D. (2) · Kathryn N Weaver, MD (1) · Sharon A Savage, M.D. (1) · Staci M Peron, Ph.D. (1)