6 enrolling by invitation. 6 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Enrolling by invitation 6 |
| Phase 1 | 1 | Enrolling by invitation 1 |
| Phase 3 | 1 | Enrolling by invitation 1 |
Follow Congenital Abnormalities: new trials by email Literature Review of Congenital Abnormalities trials Research Report on Congenital Abnormalities
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Long-Term Study of Bivamelagon in Participants With Hypothalamic Obesity (HO) Bivamelagon - Hypothalamic Obesity | Phase 2 | Enrolling by invitation | Rhythm Pharmaceuticals, Inc. | 25 | 2025-11-10 | 2026-02-10 |
| Evaluation of a Novel Nasal Conformer in Pediatric Patients use of an anatomically designed nasal conformer - Cleft Lip, Nasal Surgical Procedures | Phase 2 | Enrolling by invitation | East Tennessee Children's Hospital | 20 | 2025-06-01 | 2026-09-16 |
| Evaluating the Accuracy of Soft Tissue Prediction in Patients With Mandibular Prognathism After Orthognathic Surgery Using Handheld Scanner Versus Optical Scanner A Prospective Clinical Trial face scanning pre and post orthognathic surgery - Mandibular Prognathism, Orthognathic Surgery | Phase 1 / Phase 2 | Enrolling by invitation | Cairo University | 11 | 2024-09-24 | 2024-12-09 |
| Dexmedetomidine Sublingual Film for the Ambulatory Treatment of Hyperadrenergic Autonomic Crisis in Patients With Familial Dysautonomia Matching placebo, Dexmedetomidine - Familial Dysautonomia | Phase 2 | Enrolling by invitation | NYU Langone Health | 15 | 2024-07-01 | 2026-04-13 |
| Atorvastatin and Alkali Therapy in Patients With Autosomal Dominant Polycystic Kidney Disease Atorvastatin 20 Mg Oral Tablet, Sodium Bicarbonate 600 Mg Oral Tablet - Autosomal Dominant Polycystic Kidney Disease, Chronic Kidney Diseases | Phase 2 | Enrolling by invitation | Taipei Medical University Shuang Ho Hospital | 30 | 2023-05-01 | 2023-05-23 |
| Nitric Oxide Effect on Brain and Kidney in Pediatric Patients Undergoing Cardiopulmonary Bypass Nitric Oxide (NO) 20 part per million (ppm), Standard of care cardiopulmonary bypass - Congenital Heart Disease, Congenital Heart Defect | Phase 2 / Phase 3 | Enrolling by invitation | Vanderbilt University Medical Center | 50 | 2022-04-25 | 2025-10-08 |
Cleft Lip (1) · Dysautonomia, Familial (1) · Heart Defects, Congenital (1) · Hereditary Sensory and Autonomic Neuropathies (1) · Malocclusion, Angle Class III (1) · Polycystic Kidney, Autosomal Dominant (1) · Prognathism (1) · Renal Insufficiency, Chronic (1) · Sexual Infantilism (1)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (6) · Female Urogenital Diseases (2) · Female Urogenital Diseases and Pregnancy Complications (2) · Genetic Diseases, Inborn (2) · Male Urogenital Diseases (2) · Stomatognathic Diseases (2) · Stomatognathic System Abnormalities (2) · Urogenital Diseases (2) · Abnormalities, Multiple (1) · Autonomic Nervous System Diseases (1) · Cardiovascular Abnormalities (1) · Cardiovascular Diseases (1) · Chronic Disease (1) · Ciliopathies (1)
Atorvastatin (1) · Dexmedetomidine (1) · Nitric Oxide (1) · Sodium Bicarbonate (1) · Tablets (1)
Cairo University (1) · East Tennessee Children's Hospital (1) · NYU Langone Health (1) · Rhythm Pharmaceuticals, Inc. (1) · Taipei Medical University Shuang Ho Hospital (1) · Vanderbilt University Medical Center (1)
United States (4) · Egypt (1) · Taiwan (1) · United Kingdom (1)
Alejandra Gonzalez-Duarte, MD (1) · David Meeker, MD (1) · David P Bichell, MD (1) · Mohamed Ahmed Farid, Professor of OMFS (1) · Sameh Tarek Mekhemar, Head of Department (1)