13 completed, 8 unknown, 6 terminated, 4 active not recruiting. 37 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 37 | Completed 13, Unknown 8, Terminated 6, Active not recruiting 4, Recruiting 4, Not yet recruiting 2 |
Follow Chronic Lymphocytic Leukemia: new trials by email Literature Review of Chronic Lymphocytic Leukemia trials Research Report on Chronic Lymphocytic Leukemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| This Clinical Trial is a Single-arm, Non-randomized Pilot Trial to Determine the Safety of Administering Autologous Anti-C19 Cells (ARI-0001) and the Feasibility of Local CAR-T Cell Production in Patients Over 18 Years of Age With Relapsed/Refractory (R/R) CD19+ Hematologic Malignancies, Including R ARI-0001 T cells with anti-CD19 chimeric antigen receptor (CAR-T) - Adult B-cell Acute Lymphoblastic Leukemia, Follicular Lymphoma (FL) | Not applicable | Not yet recruiting | GUSTAVO SALGUERO | 12 | 2026-09-01 | 2026-02-17 |
| Evaluation of Skin Tests in Biotherapy Allergies Drug skin tests (investigating hypersensitivity to a biotherapy) - Locally Advanced Cutaneous Squamous Cell Carcinoma of the Head and Neck, Melanoma Neoplasms | Not applicable | Recruiting | University Hospital, Angers | 70 | 2026-06-17 | 2026-06-18 |
| Combating Cancer-Related Fatigue: A Personalized Supportive Care Program Exercise, Diet - Indolent Lymphomas, Lymphoma | Not applicable | Recruiting | UNC Lineberger Comprehensive Cancer Center | 40 | 2025-06-03 | 2026-07-01 |
| Biological and Clinical Efficacy of Shingrix in Patients With CLL serologic response evaluation - Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma | Not applicable | Not yet recruiting | Gruppo Italiano Malattie EMatologiche dell'Adulto | 312 | 2024-08-01 | 2024-05-09 |
| A Single Arm Study of Acalabrutinib Conbimed With Obinutuzumab in Chinese Patients With Previously Untreated CLL Acalabrutinib, Obinutuzumab - Chronic Lymphocytic Leukemia | Not applicable | Unknown | The First Affiliated Hospital with Nanjing Medical University | 89 | 2024-04-16 | 2024-05-09 |
| Exercise As Intervention in Chronic Lymphocytic Leukemia Exercise Training as Intervention - Chronic Lymphocytic Leukemia | Not applicable | Active not recruiting | Universidade do Porto | 11 | 2023-09-01 | 2025-03-19 |
| HEALTH4CLL2: A Randomized Waitlist Control Trial of Behavioral Interventions in Patients With Chronic Lymphocytic Leukemia Questionnaires, Fit Bit - Chronic Lymphocytic Leukemia | Not applicable | Active not recruiting | M.D. Anderson Cancer Center | 30 | 2023-05-17 | 2026-09-18 |
| Implanted Loop Recorders for Detection and Management of Arrhythmia With Bruton Tyrosine Kinase Inhibitors Medtronic LINQ-2 Insertable Cardiac Monitor (ILR) - Atrial Fibrillation, Supraventricular Arrhythmia | Not applicable | Recruiting | Northwell Health | 50 | 2023-01-01 | 2025-09-18 |
| Investigating the Role of Energy Balance Modification on Health Responses in Chronic Lymphocytic Leukaemia HIT, EXE+ Nutritional Guidance - Chronic Lymphocytic Leukemia, Frailty | Not applicable | Unknown | University of Surrey | 132 | 2022-10-14 | 2024-04-24 |
| MargheRITA (Remote Intelligence for Therapeutic Adherence) RITA (App) - Multiple Myeloma, Solitary Plasmacytoma | Not applicable | Completed | Advice Pharma Group srl | 124 | 2022-06-04 | 2024-11-06 |
| Description of the Immune Deficiency in Patients With Untreated Chronic Lymphocytic Leukemia and Search for Predictive Factors of Infectious Risk Blood sampling & Chest CT without injection - Chronic Lymphocytic Leukemia | Not applicable | Recruiting | CHU de Reims | 75 | 2022-05-10 | 2024-06-26 |
| Impact of Treatment With Targeted Therapies on the Generation of CAR T Cells in CLL Patients Peripheral blood samples withdrawal - CLL, Chronic Lymphocytic Leukemia | Not applicable | Unknown | Gruppo Italiano Malattie EMatologiche dell'Adulto | 23 | 2021-10-01 | 2022-01-04 |
| Mobilising Tumour and Immune Cells Via Exercise in Chronic Lymphocytic Leukaemia Exercise trial - Chronic Lymphocytic Leukemia, Minimal Residual Disease | Not applicable | Completed | University of Bath | 26 | 2021-10-01 | 2023-09-08 |
| Geriatric Optimization Plan to Improve Survival in Older Adult Allogeneic Hematopoietic Cell Transplant Candidates, OTIS Study Health Promotion and Education, Medical Device Usage and Evaluation, Quality-of-Life Assessment - Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia | Not applicable | Completed | Ohio State University Comprehensive Cancer Center | 30 | 2021-06-11 | 2026-04-06 |
| Pharmacists Coordinated Care Oncology Model (PCOM) for Patients Taking Oral Anti-cancer Medications Patient Reported Outcome Measure (PROM), Comprehensive Medication Review (CMR), Communications between oncology and primary care pharmacists - Chronic Myeloid Leukemia, Chronic Lymphocytic Leukemia | Not applicable | Terminated | University of Michigan Rogel Cancer Center | 6 | 2021-03-26 | 2022-11-22 |
| Oral Adherence in Hematological Oncology Agents and Impact on Comorbid Therapy Adherence Patient-reported outcome measure, Comprehensive Medication Review, Pharmacist communication - Chronic Myeloid Leukemia, Chronic Lymphocytic Leukemia | Not applicable | Unknown | University of Tennessee | 30 | 2021-02-08 | 2023-12-04 |
| Safety, Efficacy of BNT162b2 mRNA Vaccine in CLL COVID-19 serology - Chronic Lymphocytic Leukemia | Not applicable | Unknown | Bnai Zion Medical Center | 1000 | 2021-02-01 | 2021-09-17 |
| MyPal ePRO-based Early Palliative Care System in Adult Patients With Hematologic Malignancies Administration of the MyPal ePRO system - Chronic Lymphocytic Leukemia, Myelodysplastic Syndromes | Not applicable | Unknown | Centre for Research and Technology Hellas | 300 | 2021-01-01 | 2021-08-04 |
| Multiple Myeloma/Chronic Lymphocytic Leukemia Coach RCT Myeloma Coach or CLL Coach Mobile App, Springboard Beyond Cancer informational website - Multiple Myeloma, Chronic Lymphocytic Leukemia | Not applicable | Completed | Duke University | 77 | 2020-12-17 | 2023-07-03 |
| Effect of Digital Health Coaching Program on Self-efficacy and Patient Reported Outcomes of Patients With Newly Diagnosed Acute Myeloid Leukemia or Chronic Lymphocytic Leukemia Educational Intervention, Questionnaire Administration, Supportive Care - Acute Myeloid Leukemia, Chronic Lymphocytic Leukemia | Not applicable | Completed | M.D. Anderson Cancer Center | 157 | 2020-03-17 | 2023-09-18 |
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Leukemia, Lymphocytic, Chronic, B-Cell (37) · Leukemia, Myelogenous, Chronic, BCR-ABL Positive (10) · Multiple Myeloma (10) · Leukemia, Myeloid, Acute (7) · Lymphoma, Non-Hodgkin (7) · Hodgkin Disease (6) · Lymphoma, Mantle-Cell (5) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (5) · Lymphoma, Follicular (4) · Myelodysplastic Syndromes (4) · Anemia, Aplastic (3) · Anemia, Refractory, with Excess of Blasts (3) · Leukemia (3) · Lymphoma, Large B-Cell, Diffuse (3) · Motor Activity (3)
Chronic Disease (37) · Disease Attributes (37) · Hematologic Diseases (37) · Hemic and Lymphatic Diseases (37) · Immune System Diseases (37) · Immunoproliferative Disorders (37) · Leukemia, B-Cell (37) · Leukemia, Lymphoid (37) · Lymphatic Diseases (37) · Lymphoproliferative Disorders (37) · Neoplasms by Histologic Type (37) · Pathologic Processes (37) · Pathological Conditions, Signs and Symptoms (37) · Neoplasms (36) · Leukemia (34)
Exercise (3) · Cholecalciferol (2) · Cyclophosphamide (2) · Cyclosporine (2) · Early Intervention, Educational (2) · Educational Status (2) · Methods (2) · Patient Reported Outcome Measures (2) · fludarabine (2) · Alemtuzumab (1) · Basiliximab (1) · Blood Specimen Collection (1) · COVID-19 Serological Testing (1) · Diet (1) · Diet Therapy (1)
M.D. Anderson Cancer Center (4) · Duke University (3) · Gruppo Italiano Malattie EMatologiche dell'Adulto (2) · Northwell Health (2) · Scripps Health (2) · Advice Pharma Group srl (1) · All India Institute of Medical Sciences (1) · Barbara Ann Karmanos Cancer Institute (1) · Bnai Zion Medical Center (1) · CHU de Reims (1) · Centre for Research and Technology Hellas (1) · GUSTAVO SALGUERO (1) · Indiana University (1) · Institut Paoli-Calmettes (1) · Masonic Cancer Center, University of Minnesota (1)
United States (21) · France (4) · Italy (4) · United Kingdom (2) · China (1) · India (1) · Israel (1) · Portugal (1)
David Bartlett, PhD (2) · Alessandra Ferrajoli, MD (1) · Alessandro Flavio Ferri (1) · Andrea Sitlinger, MD (1) · Christopher Jensen, MD MSCR (1) · Claudio Brunstein, MD (1) · Courtney DiNardo (1) · Gustavo Salguero, MD PhD MBA (1) · Haisam Ismail, MD (1) · Jeffrey W. Andrey, M.D. (1) · Jeffrey W. Andrey, MD (1) · Jianyong Li, PhD, MD (1) · John P Campbell, PhD (1) · Julie M Vose, MD, MBA (1) · Kanti R. Rai, MD (1)
PMID 1009120, PMID 1068773, PMID 10771143, PMID 1131339, PMID 11333192, PMID 11703167, PMID 1250252, PMID 14965792, PMID 15092991, PMID 15689032, PMID 1719661, PMID 19897186, PMID 21540277, PMID 21827276, PMID 22235210, PMID 22293416, PMID 22945569, PMID 24368178, PMID 25009099, PMID 25445091, PMID 26185180, PMID 26264017, PMID 26508811, PMID 2738890, PMID 27486361, PMID 30778715, PMID 3149183, PMID 34728446, PMID 34848750, PMID 34861036, PMID 36096873, PMID 36946440, PMID 37410541, PMID 37738323, PMID 40278640, PMID 40854168, PMID 41894682, PMID 4513535, PMID 4609793, PMID 6363310, PMID 6824602, PMID 7023931, PMID 9630463
P30CA036727 (1), P50CA097274 (1)