6 completed. 6 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 6 | Completed 6 |
Follow Chronic Insomnia: new trials by email Literature Review of Chronic Insomnia trials Research Report on Chronic Insomnia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| CBT-I or Zolpidem/Trazodone for Insomnia Zolpidem, Internet Cognitive Behavioral Therapy for Insomnia (CBT-I), Trazodone - Chronic Insomnia | Phase 4 | Completed | California Pacific Medical Center Research Institute | 155 | 2022-02-25 | 2025-02-24 |
| The Study of Combination Use of Melatonin Receptor Agonist for Dose Reduction or Interruptions of Benzodiazepine (BZD) and Non-BZD Hypnotics on Chronic Insomnia Ramelteon 8mg, Placebo - Chronic Insomnia | Phase 4 | Completed | Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan | 17 | 2018-02-06 | 2024-11-20 |
| Safety and Efficacy of Chronic Hypnotic Use 2 placebo, Zolpidem CR, Eszopiclone - Chronic Insomnia | Phase 4 | Completed | Henry Ford Health System | 41 | 2015-08-05 | 2024-03-29 |
| Cognitive-Behavior Therapy for Insomnia Cognitive-Behavior Therapy, Behavior Therapy, Cognitive Therapy - Chronic Insomnia | Phase 4 | Completed | Laval University | 186 | 2008-04-01 | 2013-07-02 |
| Facilitation of Zolpidem (≥10 mg) Discontinuation Through Use of Ramelteon in Subjects With Chronic Insomnia Ramelteon and zolpidem, Placebo and zolpidem - Chronic Insomnia | Phase 4 | Completed | Takeda | 135 | 2007-04-01 | 2010-07-20 |
| Subjective Efficacy of Ramelteon on Sleep in Adults With Chronic Insomnia. Ramelteon, Placebo - Chronic Insomnia | Phase 4 | Completed | Takeda | 552 | 2006-10-01 | 2016-06-28 |
Sleep Initiation and Maintenance Disorders (6) · Parasomnias (1) · Sleep Wake Disorders (1)
Dyssomnias (6) · Mental Disorders (6) · Nervous System Diseases (6) · Sleep Disorders, Intrinsic (6) · Sleep Wake Disorders (5) · Neurologic Manifestations (1) · Pathological Conditions, Signs and Symptoms (1) · Signs and Symptoms (1)
ramelteon (3) · Zolpidem (2) · Behavior Therapy (1) · Cognitive Behavioral Therapy (1) · Eszopiclone (1) · Trazodone (1)
Takeda (2) · California Pacific Medical Center Research Institute (1) · Henry Ford Health System (1) · Laval University (1) · Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan (1)
United States (5) · Canada (1) · Japan (1)
Charles M. Morin, PhD (1) · Daniel J. Buysse, MD (1) · Katie L. Stone, PhD (1) · Timothy A Roehrs, PhD (1) · Yuichi Inoue, MD, Ph.D. (1)