3 completed, 2 unknown, 1 active not recruiting, 1 terminated. 3 Phase 1, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Completed 2, Active not recruiting 1 |
| Phase 2 | 3 | Active not recruiting 1, Completed 1, Unknown 1 |
Follow Chronic Graft vs Host Disease: new trials by email Literature Review of Chronic Graft vs Host Disease trials Research Report on Chronic Graft vs Host Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Donor Regulatory T-cells for cGVHD in Patients Who do Not Obtain Complete Remission With Ruxolitinib Regulatory T-cell enriched infusion - Chronic Graft vs Host Disease | Phase 2 | Unknown | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | 15 | 2022-03-24 | 2024-03-26 |
| A Study to Investigate the Comparative Effectiveness of Ibrutinib in Steroid Dependent/Refractory cGVHD Participants Chronic Graft vs Host Disease | Terminated | Janssen Korea, Ltd., Korea | 15 | 2021-06-21 | 2025-05-23 | |
| Donor Regulatory T-cells for Steroid-Refractory Chronic Graft-versus-host-Disease Regulatory T-cell enriched infusion - Chronic Graft vs Host Disease | Phase 1 | Completed | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | 16 | 2018-09-25 | 2022-05-23 |
| Study of Baricitinib, a JAK1/2 Inhibitor, in Chronic Graft-Versus-Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation Baricitinib - Chronic Graft vs Host Disease, Chronic Graft-Versus-Host Disease | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 24 | 2016-11-01 | 2024-10-08 |
| Alvelestat (MPH966), an Oral Neutrophil Elastase Inhibitor, in Bronchiolitis Obliterans Syndrome After Allogeneic Hematopoietic Stem Cell Transplantation MPH966 - Chronic Graft vs Host Disease, Chronic Graft-Versus-Host Disease | Phase 1 / Phase 2 | Active not recruiting | National Cancer Institute (NCI) | 14 | 2016-04-28 | 2026-10-16 |
| Predictive Biomarkers For Pediatric Chronic Graft-Versus-Host Disease Chronic Graft vs Host Disease | Unknown | University of British Columbia | 302 | 2013-11-01 | 2023-12-05 | |
| Impact of Adnexal Involvement of the Severity and Prognosis of Chronic Graft-versus-Host Disease Graft vs Host Disease, Chronic Graft vs Host Disease | Completed | Dana-Farber Cancer Institute | 12 | 2010-09-01 | 2015-03-31 |
Bronchiolitis Obliterans Syndrome (3) · Arthritis, Rheumatoid (1) · Graft vs Host Disease (1)
Immune System Diseases (4) · Bronchial Diseases (3) · Bronchiolitis (3) · Bronchiolitis Obliterans (3) · Bronchitis (3) · Graft vs Host Disease (3) · Lung Diseases (3) · Lung Diseases, Obstructive (3) · Organizing Pneumonia (3) · Respiratory Tract Diseases (3) · Arthritis (1) · Autoimmune Diseases (1) · Connective Tissue Diseases (1) · Joint Diseases (1) · Musculoskeletal Diseases (1)
baricitinib (1)
Fundación Pública Andaluza para la gestión de la Investigación en Sevilla (2) · National Cancer Institute (NCI) (2) · Dana-Farber Cancer Institute (1) · Janssen Korea, Ltd., Korea (1) · University of British Columbia (1)
United States (4) · Spain (2) · Austria (1) · Canada (1) · South Korea (1)
Geoff Cuvelier, MD (1) · Jennifer Huang, MD (1) · Kirk R Schultz, MD (1) · Najla El Jurdi, M.D. (1) · Steven Z Pavletic, M.D. (1)