13 completed. 13 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 13 | Completed 13 |
| Phase 1 | 2 | Completed 2 |
Follow Childhood Diffuse Large Cell Lymphoma: new trials by email Literature Review of Childhood Diffuse Large Cell Lymphoma trials Research Report on Childhood Diffuse Large Cell Lymphoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Donor T Cells After Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies therapeutic allogeneic lymphocytes, laboratory biomarker analysis - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Phase 2 | Completed | University of Chicago | 77 | 2013-04-04 | 2019-08-07 |
| Fludarabine Phosphate, Melphalan, and Low-Dose Total-Body Irradiation Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies fludarabine phosphate, melphalan, total-body irradiation - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Roswell Park Cancer Institute | 94 | 2012-02-28 | 2019-09-24 |
| Cyclophosphamide for Prevention of Graft-Versus-Host Disease After Allogeneic Peripheral Blood Stem Cell Transplantation in Patients With Hematological Malignancies cyclophosphamide, cyclosporine, peripheral blood stem cell transplantation - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Fred Hutchinson Cancer Center | 43 | 2011-09-01 | 2017-05-19 |
| Rituximab in Treating Patients Undergoing Donor Peripheral Blood Stem Cell Transplant for Relapsed or Refractory B-cell Lymphoma rituximab, peripheral blood stem cell transplantation, nonmyeloablative allogeneic hematopoietic stem cell transplantation - B-cell Adult Acute Lymphoblastic Leukemia, B-cell Childhood Acute Lymphoblastic Leukemia | Phase 2 | Completed | Fred Hutchinson Cancer Center | 63 | 2009-02-01 | 2018-01-02 |
| Donor Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies double-unit umbilical cord blood transplantation, cytogenetic analysis, bone marrow aspiration - Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Case Comprehensive Cancer Center | 14 | 2007-09-01 | 2019-01-23 |
| Alemtuzumab, Fludarabine Phosphate, and Total-Body Irradiation Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer alemtuzumab, total-body irradiation, fludarabine phosphate - Acute Undifferentiated Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Fred Hutchinson Cancer Center | 12 | 2005-03-01 | 2017-05-30 |
| Tacrolimus and Mycophenolate Mofetil With or Without Sirolimus in Preventing Acute Graft-Versus-Host Disease in Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer Fludarabine Phosphate, Total-Body Irradiation, Peripheral Blood Stem Cell Transplantation - Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable, Previously Treated Myelodysplastic Syndrome | Phase 2 | Completed | Fred Hutchinson Cancer Center | 210 | 2004-11-01 | 2019-10-30 |
| Rituximab, Rasburicase, and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Advanced B-Cell Leukemia or Lymphoma doxorubicin hydrochloride, cyclophosphamide, methotrexate - Childhood Burkitt Lymphoma, Childhood Diffuse Large Cell Lymphoma | Phase 2 | Completed | Children's Oncology Group | 97 | 2004-06-01 | 2014-09-19 |
| Tacrolimus and Mycophenolate Mofetil in Preventing Graft-Versus-Host Disease in Patients Who Have Undergone Total-Body Irradiation With or Without Fludarabine Phosphate Followed by Donor Peripheral Blood Stem Cell Transplant for Hematologic Cancer fludarabine phosphate, total-body irradiation, mycophenolate mofetil - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Fred Hutchinson Cancer Center | 150 | 2004-04-01 | 2020-01-29 |
| Mycophenolate Mofetil and Cyclosporine in Reducing Graft-Versus-Host Disease in Patients With Hematologic Malignancies or Metastatic Kidney Cancer Undergoing Donor Stem Cell Transplant fludarabine phosphate, total-body irradiation, nonmyeloablative allogeneic hematopoietic stem cell transplantation - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 1 / Phase 2 | Completed | Fred Hutchinson Cancer Center | 37 | 2003-09-01 | 2020-01-18 |
| Alemtuzumab, Fludarabine Phosphate, and Low-Dose Total Body Irradiation Before Donor Stem Cell Transplantation in Treating Patients With Hematological Malignancies alemtuzumab, fludarabine phosphate, total-body irradiation - Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q) | Phase 2 | Completed | Fred Hutchinson Cancer Center | 60 | 2001-11-01 | 2020-01-29 |
| Fludarabine Phosphate, Low-Dose Total-Body Irradiation, and Donor Stem Cell Transplant Followed by Cyclosporine, Mycophenolate Mofetil, Donor Lymphocyte Infusion in Treating Patients With Hematopoietic Cancer total-body irradiation, fludarabine phosphate, cyclosporine - Acute Undifferentiated Leukemia, Adult Nasal Type Extranodal NK/T-cell Lymphoma | Phase 1 / Phase 2 | Completed | Fred Hutchinson Cancer Center | 21 | 2000-05-01 | 2020-01-21 |
| Topotecan Hydrochloride in Treating Children With Meningeal Cancer That Has Not Responded to Previous Treatment topotecan hydrochloride, laboratory biomarker analysis - AIDS-related Diffuse Large Cell Lymphoma, AIDS-related Diffuse Mixed Cell Lymphoma | Phase 2 | Completed | National Cancer Institute (NCI) | 77 | 2000-04-01 | 2013-02-21 |
Burkitt Lymphoma (13) · Dendritic Cell Sarcoma, Interdigitating (13) · Lymphoma, Large B-Cell, Diffuse (13) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (12) · Leukemia, Lymphocytic, Chronic, B-Cell (11) · Lymphoma, B-Cell, Marginal Zone (11) · Lymphoma, Follicular (11) · Lymphoma, Large-Cell, Immunoblastic (11) · Lymphoma, Mantle-Cell (11) · Lymphoma, Non-Hodgkin (11) · Waldenstrom Macroglobulinemia (11) · Hodgkin Disease (10) · Leukemia, Myeloid, Acute (10) · Lymphoma, Large-Cell, Anaplastic (10) · Recurrence (10)
DNA Virus Infections (13) · Epstein-Barr Virus Infections (13) · Hemic and Lymphatic Diseases (13) · Herpesviridae Infections (13) · Histiocytic Disorders, Malignant (13) · Histiocytosis (13) · Immune System Diseases (13) · Immunoproliferative Disorders (13) · Infections (13) · Lymphatic Diseases (13) · Lymphoma (13) · Lymphoma, B-Cell (13) · Lymphoproliferative Disorders (13) · Neoplasms (13) · Neoplasms by Histologic Type (13)
Peripheral Blood Stem Cell Transplantation (9) · Mycophenolic Acid (8) · Whole-Body Irradiation (8) · fludarabine phosphate (8) · Cyclosporine (6) · Cyclophosphamide (3) · Tacrolimus (3) · Alemtuzumab (2) · Busulfan (2) · Methotrexate (2) · Methylprednisolone (2) · Methylprednisolone Acetate (2) · Methylprednisolone Hemisuccinate (2) · Rituximab (2) · merphos (2)
Fred Hutchinson Cancer Center (8) · Case Comprehensive Cancer Center (1) · Children's Oncology Group (1) · National Cancer Institute (NCI) (1) · Roswell Park Cancer Institute (1) · University of Chicago (1)
United States (13) · Italy (5) · Germany (2) · Denmark (1)
Brenda Sandmaier (4) · David Maloney (3) · Brenda Cooper, MD (1) · George Chen (1) · Hongtao Liu (1) · Marco Mielcarek (1) · Mitchell Cairo, MD CCRP (1) · Susan Blaney (1)
PMID 32499241, PMID 19900571, PMID 25085357, PMID 26764356, PMID 30117142, PMID 31481800
P30CA015704 (8), P01CA018029 (4), P01CA078902 (3), U10CA098543 (2)