4 completed. 4 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Completed 4 |
Follow Childhood Central Nervous System Embryonal Tumor: new trials by email Literature Review of Childhood Central Nervous System Embryonal Tumor trials Research Report on Childhood Central Nervous System Embryonal Tumor
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Vorinostat and Temozolomide in Treating Young Patients With Relapsed or Refractory Primary Brain Tumors or Spinal Cord Tumors vorinostat, temozolomide, diagnostic laboratory biomarker analysis - Childhood Atypical Teratoid/Rhabdoid Tumor, Childhood Central Nervous System Choriocarcinoma | Phase 1 | Completed | National Cancer Institute (NCI) | 27 | 2010-02-01 | 2013-05-03 |
| Pazopanib Hydrochloride in Treating Young Patients With Solid Tumors That Have Relapsed or Not Responded to Treatment pazopanib hydrochloride, pharmacological study - Childhood Central Nervous System Choriocarcinoma, Childhood Central Nervous System Embryonal Tumor | Phase 1 | Completed | National Cancer Institute (NCI) | 55 | 2009-06-01 | 2013-09-30 |
| Sunitinib in Treating Young Patients With Refractory Solid Tumors sunitinib malate, pharmacological study, dynamic contrast-enhanced magnetic resonance imaging - Central Nervous System Metastases, Childhood Central Nervous System Choriocarcinoma | Phase 1 | Completed | National Cancer Institute (NCI) | 35 | 2006-10-01 | 2014-01-28 |
| Combination Chemotherapy in Treating Young Patients With Advanced Solid Tumors oxaliplatin, fluorouracil, leucovorin calcium - Childhood Central Nervous System Choriocarcinoma, Childhood Central Nervous System Embryonal Tumor | Phase 1 | Completed | National Cancer Institute (NCI) | 42 | 2005-09-01 | 2013-05-03 |
Optic Nerve Glioma (2) · Astrocytoma (1) · Choroid Plexus Neoplasms (1) · Familial ependymoma (1) · Medulloblastoma (1) · Oligodendroglioma (1) · Paraganglioma, Extra-Adrenal (1) · Rhabdoid Tumor (1) · Spinal Cord Neoplasms (1)
Cranial Nerve Diseases (2) · Cranial Nerve Neoplasms (2) · Eye Diseases (2) · Glioma (2) · Neoplasms (2) · Neoplasms by Histologic Type (2) · Neoplasms by Site (2) · Neoplasms, Germ Cell and Embryonal (2) · Neoplasms, Glandular and Epithelial (2) · Neoplasms, Nerve Tissue (2) · Neoplasms, Neuroepithelial (2) · Nervous System Diseases (2) · Nervous System Neoplasms (2) · Neuroectodermal Tumors (2) · Optic Nerve Diseases (2)
2-phenyl-6-(2'-(4'-(ethoxycarbonyl)thiazolyl))thiazolo(3,2-b)(1,2,4)triazole (1) · Fluorouracil (1) · Leucovorin (1) · Magnetic Resonance Spectroscopy (1) · Oxaliplatin (1) · Sunitinib (1) · Temozolomide (1) · Vorinostat (1) · pazopanib (1)
National Cancer Institute (NCI) (4)
United States (4) · Canada (2)
Julia Glade-Bender (1) · Lia Gore (1) · Steven DuBois (1) · Trent Hummel (1)
PMID 23554030, PMID 23857966, PMID 32623479, PMID 33852135
U01CA097452 (3)