8 completed, 2 terminated. 3 Phase 2, 3 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Completed 2, Terminated 1 |
| Phase 3 | 3 | Completed 3 |
| Phase 1 | 1 | Terminated 1 |
Follow Childhood Acute Myeloblastic Leukemia Without Maturation (M1): new trials by email Literature Review of Childhood Acute Myeloblastic Leukemia Without Maturation (M1) trials Research Report on Childhood Acute Myeloblastic Leukemia Without Maturation (M1)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Donor Stem Cell Transplant in Treating Patients With High Risk Acute Myeloid Leukemia mitoxantrone hydrochloride, cytarabine, peripheral blood stem cell transplantation - Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Monoblastic Leukemia (M5a) | Phase 1 | Terminated | University of Southern California | 10 | 2013-03-06 | 2018-03-30 |
| Studying Biomarkers in Samples From Younger Patients With Acute Myeloid Leukemia laboratory biomarker analysis - Childhood Acute Monoblastic Leukemia (M5a), Childhood Acute Monocytic Leukemia (M5b) | Completed | Children's Oncology Group | 20 | 2012-08-01 | 2016-05-19 | |
| Biomarkers in Bone Marrow Samples From Pediatric Patients With High-Risk Acute Myeloid Leukemia laboratory biomarker analysis - Childhood Acute Basophilic Leukemia, Childhood Acute Eosinophilic Leukemia | Completed | Children's Oncology Group | 250 | 2010-03-01 | 2016-05-19 | |
| Identification of de Novo Fanconi Anemia in Younger Patients With Newly Diagnosed Acute Myeloid Leukemia laboratory biomarker analysis - Childhood Acute Erythroleukemia (M6), Childhood Acute Megakaryocytic Leukemia (M7) | Completed | Children's Oncology Group | 20 | 2009-05-01 | 2016-05-17 | |
| Bortezomib and Combination Chemotherapy in Treating Younger Patients With Recurrent, Refractory, or Secondary Acute Myeloid Leukemia idarubicin, cytarabine, bortezomib - Adult Acute Monoblastic Leukemia (M5a), Adult Acute Monocytic Leukemia (M5b) | Phase 2 | Completed | National Cancer Institute (NCI) | 52 | 2008-04-01 | 2018-05-22 |
| Combination Chemotherapy in Treating Young Patients With Down Syndrome and Acute Myeloid Leukemia or Myelodysplastic Syndromes asparaginase, daunorubicin hydrochloride, cytarabine - Childhood Acute Basophilic Leukemia, Childhood Acute Eosinophilic Leukemia | Phase 3 | Completed | Children's Oncology Group | 205 | 2007-03-01 | 2022-01-28 |
| Idarubicin and Cytarabine With or Without Bevacizumab in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia idarubicin, cytarabine, bevacizumab - Adult Acute Basophilic Leukemia, Adult Acute Eosinophilic Leukemia | Phase 2 | Terminated | National Cancer Institute (NCI) | 120 | 2004-10-01 | 2013-01-24 |
| Combination Chemotherapy With or Without PSC 833, Peripheral Stem Cell Transplantation, and/or Interleukin-2 in Treating Patients With Acute Myeloid Leukemia cytarabine, daunorubicin hydrochloride, etoposide - Adult Acute Basophilic Leukemia, Adult Acute Eosinophilic Leukemia | Phase 3 | Completed | National Cancer Institute (NCI) | 720 | 2000-11-01 | 2013-06-04 |
| Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Children With Acute Myelogenous Leukemia or Myelodysplastic Syndrome asparaginase, daunorubicin hydrochloride, fludarabine phosphate - Childhood Acute Erythroleukemia (M6), Childhood Acute Megakaryocytic Leukemia (M7) | Phase 3 | Completed | National Cancer Institute (NCI) | 880 | 1996-08-01 | 2013-01-16 |
| High-Dose Busulfan and High-Dose Cyclophosphamide Followed By Donor Bone Marrow Transplant in Treating Patients With Leukemia, Myelodysplastic Syndrome, Multiple Myeloma, or Recurrent Hodgkin or Non-Hodgkin Lymphoma busulfan, cyclophosphamide, allogeneic bone marrow transplantation - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Case Comprehensive Cancer Center | 13 | 1988-03-01 | 2010-08-09 |
Congenital Abnormalities (5) · Leukemia, Eosinophilic, Acute (5) · Leukemia, Monocytic, Acute (5) · Leukemia, Myeloid, Acute (5) · Leukemia, Myelomonocytic, Acute (5) · Leukemia, Erythroblastic, Acute (4) · Leukemia, Megakaryoblastic, Acute (4) · Anemia, Refractory (2) · Anemia, Refractory, with Excess of Blasts (2) · Leukemia, Basophilic, Acute (2) · Leukemia, Myelomonocytic, Chronic (2) · Burkitt Lymphoma (1) · Fanconi Anemia (1) · Hodgkin Disease (1) · Immunoblastic Lymphadenopathy (1)
Hematologic Diseases (9) · Hemic and Lymphatic Diseases (9) · Leukemia (9) · Leukemia, Myeloid (9) · Neoplasms (9) · Neoplasms by Histologic Type (9) · Bone Marrow Diseases (6) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (6) · Myeloproliferative Disorders (4) · Chronic Disease (3) · Disease Attributes (3) · Pathologic Processes (3) · Pathological Conditions, Signs and Symptoms (3) · Anemia (2) · Leukemia, Myeloid, Acute (2)
Cytarabine (6) · Etoposide (4) · Busulfan (3) · Daunorubicin (3) · Idarubicin (3) · Asparaginase (2) · Cyclophosphamide (2) · Filgrastim (2) · Granulocyte Colony-Stimulating Factor (2) · Interleukin-2 (2) · Methotrexate (2) · Peripheral Blood Stem Cell Transplantation (2) · Thioguanine (2) · Transplantation (2) · aldesleukin (2)
Children's Oncology Group (4) · National Cancer Institute (NCI) (4) · Case Comprehensive Cancer Center (1) · University of Southern California (1)
United States (10) · Australia (2) · Canada (2) · Puerto Rico (1)
Ann Mohrbacher (1) · Beverly Lange (1) · Hillard Lazarus (1) · Jeffrey Moscow (1) · Jeffrey Taub, MD (1) · Jonathan Kolitz (1) · Monica Thakar, MD (1) · Soheil Meshinchi, MD (1) · Srdan Verstovsek (1) · Stephanie Heidemann, MD (1)
PMID 19304957, PMID 20056794, PMID 20413658, PMID 20522709, PMID 28389462, PMID 31375516, PMID 36184192, PMID 36815378, PMID 38295280, PMID 42085603
U10CA098543 (4), N01CM62202 (1), N01CM62204 (1), U10CA031946 (1)