63 completed. 63 Phase 1, 34 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 63 | Completed 63 |
| Phase 2 | 34 | Completed 34 |
Follow Bronchiolitis: new trials by email Literature Review of Bronchiolitis trials Research Report on Bronchiolitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Double-Blind, Active-Controlled, Multiple-Ascending Dose Study of Aerosolized RSP-1502 in Subjects With CF and Chronic PA Lung Infection RSP-1502, Tobramycin inhalation solution - Cystic Fibrosis Lung, Respiratory Infections, Recurrent, Chronic | Phase 1 / Phase 2 | Completed | Respirion Pharmaceuticals Pty Ltd | 71 | 2024-04-01 | 2026-06-25 |
| Safety, Tolerability, Pharmacokinetics, and Food Effect Study of RV299 in Healthy Adults RV299, Placebo, Midazolam - Respiratory Syncytial Virus Infections | Phase 1 | Completed | Pfizer | 50 | 2021-11-12 | 2023-09-13 |
| Study of Ruxolitinib for Acute and Chronic Graft Versus Host Disease Ruxolitinib - Acute-graft-versus-host Disease, Chronic Graft-versus-host-disease | Phase 1 | Completed | Children's Hospital Medical Center, Cincinnati | 13 | 2021-10-27 | 2024-01-16 |
| Hp129 Xenon Imaging and BOS in Lung Transplantation Hp 129Xenon - Bronchiolitis Obliterans | Phase 1 / Phase 2 | Completed | Children's Hospital Medical Center, Cincinnati | 3 | 2020-09-09 | 2026-09-18 |
| A Clinical Trial to Determine the Safety and Efficacy of Hope Biosciences Autologous Mesenchymal Stem Cell Therapy for the Treatment of Traumatic Brain Injury and Hypoxic-Ischemic Encephalopathy HB-adMSCs - Traumatic Brain Injury | Phase 1 / Phase 2 | Completed | Hope Biosciences LLC | 24 | 2020-01-01 | 2026-01-15 |
| A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of AMG 592 in Healthy Japanese Participants AMG 592, Placebo - Chronic Graft-versus-Host Disease (cGVHD) | Phase 1 | Completed | Amgen | 18 | 2019-01-29 | 2023-06-02 |
| Phase 1/2 Dose Finding and Safety Study of Ibrutinib in Pediatric Subjects With Chronic Graft Versus Host Disease (cGVHD) Ibrutinib - Chronic Graft Versus Host Disease | Phase 1 / Phase 2 | Completed | Pharmacyclics LLC. | 59 | 2018-11-19 | 2025-10-21 |
| A Phase 1/2 Study to Evaluate Axatilimab in Participants With Active cGVHD axatilimab - Chronic Graft-versus-host-disease | Phase 1 / Phase 2 | Completed | Syndax Pharmaceuticals | 41 | 2018-11-01 | 2025-09-15 |
| The Safety and Tolerability of Pirfenidone for BOS After HCT Pirfenidone 267 MG [Esbriet] - Bronchiolitis Obliterans, Graft Vs Host Disease | Phase 1 | Completed | Stanford University | 30 | 2018-03-01 | 2022-06-13 |
| SynRinse Irrigation Pilot (SIP) Trial Synrinse - Sinusitis, Chronic, Cystic Fibrosis With Other Manifestations | Phase 1 / Phase 2 | Completed | University of Washington | 30 | 2017-06-06 | 2018-10-17 |
| A Drug Interaction Study to Assess the Pharmacokinetics of Narlaprevir and Antiretroviral Drugs Narlaprevir, Ritonavir, Tenofovir Disoproxil Fumarate - Healthy | Phase 1 | Completed | R-Pharm | 36 | 2017-04-24 | 2019-02-19 |
| Intrathecal Administration of Expanded Wharton's Jelly Mesenchymal Stem Cells in Chronic Traumatic Spinal Cord Injury XCEL-UMC-BETA, Placebo - Spinal Cord Injury, Chronic | Phase 1 / Phase 2 | Completed | Banc de Sang i Teixits | 10 | 2016-12-27 | 2020-02-17 |
| Study of ProTmune for Allogeneic HCT in Adult Patients With Hematologic Malignancies ProTmune, Control Arm - Hematologic Malignancies, Acute Myeloid Leukemia | Phase 1 / Phase 2 | Completed | Fate Therapeutics | 96 | 2016-12-20 | 2023-02-08 |
| Study of Baricitinib, a JAK1/2 Inhibitor, in Chronic Graft-Versus-Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation Baricitinib - Chronic Graft vs Host Disease, Chronic Graft-Versus-Host Disease | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 24 | 2016-11-01 | 2024-10-08 |
| Multiple Donor Treg DLI for Severe Refractory Chronic GVHD T reg DLI - Chronic Graft Versus Host Disease | Phase 1 / Phase 2 | Completed | Mario Arpinati | 18 | 2016-08-03 | 2023-02-02 |
| A Study to Evaluate the Safety, Tolerability, Immunogenicity, Pharmacokinetics, and Pharmacodynamics of AMG 592 in Healthy Participants AMG 592, Placebo - Chronic Graft-versus-host Disease (cGVHD) | Phase 1 | Completed | Amgen | 64 | 2015-10-19 | 2023-05-24 |
| Study of Individual Adult and Pediatric Patient Dose-escalated Interleukin-2 Therapy for Refractory Chronic GVHD Interleukin-2 - Chronic Versus Graft Host Disease | Phase 1 | Completed | Dana-Farber Cancer Institute | 21 | 2015-02-01 | 2020-06-23 |
| BMT Autologous MSCs for GvHD Autologous mesenchymal stromal cells (MSCs) - Graft Versus Host Disease, Acute Graft Versus Host Disease | Phase 1 | Completed | Emory University | 11 | 2015-01-01 | 2023-01-12 |
| Allogenic Bone Marrow Mesenchymal Stem Cells Infusion in Patients With Steroid-refractory GVHD Mesenchymal Stem Cells - Graft Versus Host Disease | Phase 1 / Phase 2 | Completed | National Institute of Blood and Marrow Transplant (NIBMT), Pakistan | 10 | 2015-01-01 | 2017-01-25 |
| Study of the Bruton's Tyrosine Kinase Inhibitor in Subjects With Chronic Graft Versus Host Disease Ibrutinib - Graft Versus Host Disease | Phase 1 / Phase 2 | Completed | Pharmacyclics LLC. | 45 | 2014-07-14 | 2019-07-11 |
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Bronchiolitis Obliterans Syndrome (53) · Graft vs Host Disease (11) · Leukemia (8) · Bronchiolitis Obliterans (6) · Neoplasms (5) · Hepatitis C (4) · Leukemia, Lymphocytic, Chronic, B-Cell (4) · Lymphoma (4) · Lymphoma, Follicular (4) · Hematologic Neoplasms (3) · Multiple Myeloma (3) · Stroke (3) · Hematologic Diseases (2) · Immune System Diseases (2)
Bronchial Diseases (63) · Bronchitis (63) · Lung Diseases, Obstructive (63) · Respiratory Tract Diseases (63) · Lung Diseases (62) · Organizing Pneumonia (53) · Bronchiolitis Obliterans (51) · Immune System Diseases (51) · Graft vs Host Disease (42) · Pathological Conditions, Signs and Symptoms (17) · Hemic and Lymphatic Diseases (16) · Infections (15) · Pathologic Processes (15) · Neoplasms by Histologic Type (14)
Interleukin-2 (2) · KW-2478 (2) · Rituximab (2) · Saline Solution (2) · Sirolimus (2) · Tacrolimus (2) · ibrutinib (2) · ofatumumab (2) · 4-(cyclopropylamino)-2-((4-(4-(ethylsulfonyl)piperazin-1-yl)phenyl)amino)pyrimidine-5-carboxamide (1) · AZD-3199 (1) · Abatacept (1) · Alemtuzumab (1) · Bortezomib (1) · Busulfan (1) · Compression Bandages (1)
Hoffmann-La Roche (4) · Dana-Farber Cancer Institute (3) · Pharmacyclics LLC. (3) · Amgen (2) · Children's Hospital Medical Center, Cincinnati (2) · Genta Incorporated (2) · H. Lee Moffitt Cancer Center and Research Institute (2) · Kyowa Kirin Co., Ltd. (2) · Alexion Pharmaceuticals, Inc. (1) · Andalusian Initiative for Advanced Therapies - Fundación Pública Andaluza Progreso y Salud (1) · ArQule, Inc., a subsidiary of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. (Rahway, NJ USA) (1) · AstraZeneca (1) · Banc de Sang i Teixits (1) · Beth Israel Deaconess Medical Center (1) · Beyond Air Inc. (1)
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Aldo T Iacono, MD (1) · Alexander Thompson, MD, PhD (1) · Amir Kugelman (1) · Anthony Rosner, PhD (1) · Arthur Tucker, PhD (1) · Asher Tal, M.D (1) · Attilio Olivieri, MD (1) · Carin Jorup, MD (1) · Carlos Solano Vercet, MD (1) · Carmen Regidor, MD (1) · Charles S Cox, MD (1)
PMID 16186597, PMID 18214942, PMID 22129252, PMID 23861248, PMID 23903014, PMID 26059242, PMID 26945226, PMID 28072473, PMID 28924018, PMID 29549175, PMID 29843792, PMID 30333224, PMID 31260802, PMID 31471324, PMID 32981857, PMID 34102349, PMID 34649279, PMID 35641662, PMID 36189324, PMID 36459673, PMID 36862975, PMID 39704205, PMID 40554417, PMID 42200447
2009 (2), 2017 (1)