3 completed, 1 active not recruiting. 4 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Completed 3, Active not recruiting 1 |
| Phase 2 | 1 | Completed 1 |
Follow Breakthrough Pain: new trials by email Literature Review of Breakthrough Pain trials Research Report on Breakthrough Pain
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Dexamethasone-Enhanced TAP Block in Lapchole Dexamethasone enhanced TAP Block, Marcaine- 0.25% - Laparoscopic Cholecystectomy | Phase 1 | Active not recruiting | Makassed General Hospital | 100 | 2025-08-19 | 2025-09-19 |
| Efficacy of Injectable Fentanyl in Sublingual Route Versus Oral Morphine Syrup for Breakthrough Pain Fentanyl Citrate 50Mcg/Ml Inj_#1, Morphine - Pain, Breakthrough | Phase 1 / Phase 2 | Completed | Department of Medical Services Ministry of Public Health of Thailand | 20 | 2021-06-15 | 2022-08-31 |
| Staccato Fentanyl Single and Multidose PK Inhaled Placebo, Inhaled Fentanyl 25 mcg, Intravenous Fentanyl 25 mcg - Breakthrough Pain | Phase 1 | Completed | Alexza Pharmaceuticals, Inc. | 51 | 2006-04-01 | 2017-03-15 |
| Sublingual Methadone for the Management of Cancer Breakthrough Pain Methadone - Cancer, Pain | Phase 1 | Completed | AHS Cancer Control Alberta | 10 | 2003-09-01 | 2017-09-25 |
Pain (2) · Acute Pain (1) · Agnosia (1) · Cancer Pain (1) · Neoplasms (1)
Neurologic Manifestations (4) · Pathological Conditions, Signs and Symptoms (4) · Signs and Symptoms (4) · Pain (2) · Nervous System Diseases (1) · Neurobehavioral Manifestations (1) · Perceptual Disorders (1)
Fentanyl (1) · Methadone (1) · Morphine (1)
AHS Cancer Control Alberta (1) · Alexza Pharmaceuticals, Inc. (1) · Department of Medical Services Ministry of Public Health of Thailand (1) · Makassed General Hospital (1)
Lebanon (1) · Thailand (1) · United States (1)
Neil Hagen (1) · Thanvarat Tilagul (1) · Tong J Gan, MD (1)
PMID 10353500, PMID 18258412, PMID 19508134, PMID 21215653, PMID 23380337, PMID 24385406, PMID 36600856, PMID 37083674, PMID 37170709, PMID 38782390, PMID 39709396