7 terminated. 7 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 7 | Terminated 7 |
| Phase 2 | 4 | Terminated 4 |
Follow Brain Tumor: new trials by email Literature Review of Brain Tumor trials Research Report on Brain Tumor
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Tumor Treating Fields With Chemoradiation in Newly Diagnosed GBM Tumor Treating Fields, Temozolomide, Radiation Therapy - Glioblastoma, Cancer of Brain | Phase 1 | Terminated | Providence Health & Services | 7 | 2019-12-02 | 2024-03-04 |
| [18F]Fluciclovine and [18F]FLT PET/CT Assessment of Primary High-Grade Brain Tumors [18F]FLT, [18F]Fluciclovine - Brain Tumor | Phase 1 / Phase 2 | Terminated | University of Utah | 10 | 2018-09-24 | 2024-12-27 |
| Zotiraciclib (TG02) Plus Dose-Dense or Metronomic Temozolomide Followed by Randomized Phase II Trial of Zotiraciclib (TG02) Plus Temozolomide Versus Temozolomide Alone in Adults With Recurrent Anaplastic Astrocytoma and Glioblastoma Zotiraciclib (TG02), Temozolomide (TMZ) - Brain Tumor, Astrocytoma | Phase 1 / Phase 2 | Terminated | National Cancer Institute (NCI) | 53 | 2016-12-14 | 2026-02-23 |
| Dendritic Cell Vaccine Therapy With In Situ Maturation in Pediatric Brain Tumors Dendritic Cell Vaccine, Tumor Lysate, Imiquimod - Glioma, Brain Cancer | Phase 1 | Terminated | Edward Ziga | 1 | 2013-09-03 | 2017-03-10 |
| Tolerability Study of Xerecept® in Pediatric Patients XERECEPT - Brain Edema, Brain Tumor | Phase 1 / Phase 2 | Terminated | Celtic Pharma Development Services | 15 | 2010-06-01 | 2013-07-30 |
| A Study of Intraventricular Liposomal Encapsulated Ara-C (DepoCyt) in Patients With Recurrent Glioblastoma ITV DepoCyt + Temozolomide - Glioblastoma Multiforme, Glioma | Phase 1 / Phase 2 | Terminated | Medical University of South Carolina | 12 | 2009-09-01 | 2019-02-12 |
| RTA 744 Injection in Patients With Leptomeningeal Disease RTA 744 - Neoplastic Meningitis, Solid Tumor | Phase 1 | Terminated | M.D. Anderson Cancer Center | 7 | 2006-09-01 | 2016-05-16 |
Brain Neoplasms (7) · Glioblastoma (4) · Astrocytoma (2) · Glioma (2) · Brain Edema (1) · Edema (1) · Gliosarcoma (1) · Leukemia (1) · Lymphoma (1) · Meningeal Carcinomatosis (1) · Meningeal Neoplasms (1) · Recurrence (1)
Brain Diseases (7) · Central Nervous System Diseases (7) · Central Nervous System Neoplasms (7) · Neoplasms (7) · Neoplasms by Site (7) · Nervous System Diseases (7) · Nervous System Neoplasms (7) · Neoplasms by Histologic Type (5) · Neoplasms, Germ Cell and Embryonal (4) · Neoplasms, Glandular and Epithelial (4) · Neoplasms, Nerve Tissue (4) · Neoplasms, Neuroepithelial (4) · Neuroectodermal Tumors (4) · Astrocytoma (2) · Glioma (2)
Temozolomide (3) · 14-methyl-20-oxa-5,7,14,26-tetraazatetracyclo(19.3.1.1(2,6).1(8,12))heptacosa-1(25),2(26),3,5,8(27),9,11,16,21,23-decaene (1) · Blood Component Removal (1) · Corticotropin-Releasing Hormone (1) · Imiquimod (1) · Leukapheresis (1) · Radiotherapy (1) · WP 744 (1) · alovudine (1) · fluciclovine F-18 (1) · lentiviral minigene vaccine of COVID-19 coronavirus (1)
Celtic Pharma Development Services (1) · Edward Ziga (1) · M.D. Anderson Cancer Center (1) · Medical University of South Carolina (1) · National Cancer Institute (NCI) (1) · Providence Health & Services (1) · University of Utah (1)
United States (7)
Bruce M Frankel, MD (1) · Edward Ziga, MD (1) · Gustavo Leone (1) · Jeffrey Yap, PhD (1) · Jing Wu, M.D. (1) · Morris D. Groves, MD (1) · Ricky Chen, MD (1) · Stewart Goldman, MD (1)