2 recruiting, 1 completed, 1 terminated. 4 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Recruiting 2, Completed 1, Terminated 1 |
| Phase 2 | 1 | Recruiting 1 |
Follow Brain Tumor, Primary: new trials by email Literature Review of Brain Tumor, Primary trials Research Report on Brain Tumor, Primary
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Focused Ultrasound Blood-Brain Barrier Disruption for the Treatment of High-Grade Glioma in Patients Undergoing Standard Chemotherapy Focused Ultrasound Next Generation Dome Helmet, Definity® Vial for (Perflutren Lipid Microsphere) Injectable Suspension - GBM, Glioblastoma Multiforme (GBM) | Phase 1 | Recruiting | Sunnybrook Health Sciences Centre | 10 | 2025-06-04 | 2025-09-17 |
| Study of PBI-200 in Subjects With NTRK-Fusion-Positive Solid Tumors PBI-200 - Solid Tumor, Adult, Brain Tumor, Primary | Phase 1 | Terminated | Pyramid Biosciences | 29 | 2021-07-20 | 2024-03-28 |
| Oral Capecitabine and Temozolomide (CAPTEM) for Newly Diagnosed GBM Capecitabine, Temozolomide - Glioblastoma Multiforme (GBM), Glioblastoma | Phase 1 / Phase 2 | Recruiting | Northwell Health | 67 | 2017-06-13 | 2026-06-01 |
| Two-Part Study to Evaluate the Safety and Efficacy of Image Guided Surgery Using Indocyanine Green for Intramolecular Imaging of Nervous System Tumors Compared to Standard of Care, (TumorGlow) Indocyanine Green - Brain Tumor, Primary, Brain Tumor, Recurrent | Phase 1 | Completed | University of Pennsylvania | 363 | 2015-06-01 | 2026-01-23 |
Brain Neoplasms (4) · Glioblastoma (2) · Desmoplastic Small Round Cell Tumor (1) · Glioma (1) · Neoplasms (1)
Brain Diseases (4) · Central Nervous System Diseases (4) · Central Nervous System Neoplasms (4) · Neoplasms by Site (4) · Nervous System Diseases (4) · Nervous System Neoplasms (4) · Neoplasms (3) · Neoplasms by Histologic Type (3) · Astrocytoma (2) · Neoplasms, Germ Cell and Embryonal (2) · Neoplasms, Glandular and Epithelial (2) · Neoplasms, Nerve Tissue (2) · Neoplasms, Neuroepithelial (2) · Neuroectodermal Tumors (2) · Glioma (1)
Capecitabine (1) · Indocyanine Green (1) · Temozolomide (1)
Northwell Health (1) · Pyramid Biosciences (1) · Sunnybrook Health Sciences Centre (1) · University of Pennsylvania (1)
United States (2) · Australia (1) · Canada (1) · Denmark (1) · France (1) · Germany (1) · Hong Kong (1) · Italy (1) · Singapore (1) · South Korea (1) · Spain (1) · United Kingdom (1)
John Boockvar, MD (1) · John Y.K. Lee, MD (1) · Nir Lipsman (1)