5 completed, 1 unknown. 6 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 6 | Completed 5, Unknown 1 |
| Phase 2 | 1 | Unknown 1 |
Follow Botulism: new trials by email Literature Review of Botulism trials Research Report on Botulism
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of the Drug B11-FC (Botulism Treatment) B11-FC, Botulinum neurotoxin type A, Placebo - Botulism | Phase 1 / Phase 2 | Unknown | Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation | 40 | 2024-08-01 | 2024-08-30 |
| Effect of Amifampridine on Neuromuscular Transmission in Patients Treated With OnabotulinumtoxinA Amifampridine - Botulism, Iatrogenic Botulism | Phase 1 | Completed | Wake Forest University Health Sciences | 21 | 2023-09-15 | 2025-02-03 |
| Study to Evaluate Safety and PK of a Single IM Dose of G03-52-01 vs Placebo in Adult Subjects G03-52-01, Placebo - Healthy | Phase 1 | Completed | Alachua Government Services, Inc. | 40 | 2020-06-01 | 2024-10-04 |
| A Study to Evaluate the Safety and Pharmacokinetics of NTM-1633 vs Placebo Administered Intravenously in Healthy Adults NTM-1633, Placebo - Botulism | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 24 | 2018-09-25 | 2022-06-22 |
| Phase I, Dose Escalation Study to Evaluate the Safety and Pharmacokinetics of NTM-1632 NTM-1632, Placebo - Botulism | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 24 | 2016-08-01 | 2018-10-29 |
| Phase 1 PK Study of XOMA 3AB XOMA 3AB, Placebo - Botulism | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 24 | 2011-05-01 | 2014-12-05 |
Bacterial Infections (6) · Bacterial Infections and Mycoses (6) · Chemically-Induced Disorders (6) · Clostridium Infections (6) · Foodborne Diseases (6) · Gram-Positive Bacterial Infections (6) · Infections (6) · Nervous System Diseases (6) · Neuromuscular Diseases (6) · Neuromuscular Junction Diseases (6) · Neurotoxicity Syndromes (6) · Poisoning (6)
Amifampridine (1) · Botulinum Toxins, Type A (1)
National Institute of Allergy and Infectious Diseases (NIAID) (3) · Alachua Government Services, Inc. (1) · Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation (1) · Wake Forest University Health Sciences (1)
United States (5)
Cassandra Key, MD (1) · James B Caress, MD (1)