5 recruiting, 1 completed, 1 not yet recruiting, 1 terminated. 3 Phase 1, 2 Phase 2, 1 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Completed 1, Recruiting 1, Terminated 1 |
| Phase 2 | 2 | Not yet recruiting 1, Recruiting 1 |
| Not applicable | 1 | Recruiting 1 |
Follow Appendiceal Adenocarcinoma: new trials by email Literature Review of Appendiceal Adenocarcinoma trials Research Report on Appendiceal Adenocarcinoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Phase II Study of Ivonescimab Combined With Intraperitoneal Paclitaxel in Patients With High-Grade Metastatic Appendiceal Adenocarcinoma (AA) Ivonescimab, IP PTX - Phase II, Ivonescimab | Phase 2 | Not yet recruiting | M.D. Anderson Cancer Center | 30 | 2027-01-16 | 2026-08-27 |
| TLR9 Immunotherapy for Peritoneal Carcinomatosis ACM-CpG - Malignant Ascites, Colorectal Adenocarcinoma | Phase 1 | Recruiting | Brown University | 24 | 2026-08-25 | 2026-10-01 |
| Ph II Intraperitoneal Paclitaxel + System Therapy in GI Ca w/Peritoneal Carcinomatosis (STOPGAP-B) Paclitaxel Q2W, Paclitaxcel Q3W - Esophageal Carcinoma, Gastric Cancer (Diagnosis) | Phase 2 | Recruiting | University of California, Irvine | 55 | 2026-08-04 | 2026-08-31 |
| Molecular Profiling for Risk Stratification in Appendiceal Cancer DNA Methylation Profiling, m6A Epitranscriptomic Profiling - Appendiceal Cancer, Appendiceal Adenocarcinoma | Recruiting | City of Hope Medical Center | 400 | 2026-05-01 | 2026-06-29 | |
| A Study to Investigate APL-5125 in Adults With Advanced Solid Tumors APL-5125 - Colorectal Cancer, Cholangiocarcinoma | Phase 1 | Completed | Apollo Therapeutics Ltd | 27 | 2024-06-18 | 2026-10-05 |
| A Prospective Feasibility Study Using ctDNA to Tailor Neoadjuvant Chemotherapy for Patients With Colorectal or Appendiceal Adenocarcinoma Circulating tumoral DNA directed neoadjuvant therapy arm - Appendiceal Adenocarcinoma, Colorectal | Not applicable | Recruiting | M.D. Anderson Cancer Center | 48 | 2023-12-04 | 2026-05-18 |
| Genetics of Appendix Cancer Study Genetic profiling, Retrospective tissue procurement - Appendix Cancer, Appendiceal Cancer | Recruiting | Andreana Holowatyj, PhD, MSCI | 700 | 2022-11-11 | 2025-04-18 | |
| A Study of SGN-STNV in Advanced Solid Tumors SGN-STNV - Carcinoma, Non-Small Cell Lung, HER2 Negative Breast Neoplasms | Phase 1 | Terminated | Seagen Inc. | 111 | 2021-01-18 | 2025-02-07 |
Adenocarcinoma, Mucinous (8) · Appendiceal Neoplasms (2) · Colorectal Neoplasms (2) · Esophageal Neoplasms (2) · Ovarian Neoplasms (2) · Stomach Neoplasms (2) · Carcinoma, Non-Small-Cell Lung (1) · Cholangiocarcinoma (1) · Disease (1) · Endometrial Neoplasms (1) · Neoplasm Metastasis (1) · Neoplasms (1) · Peritoneal Neoplasms (1) · Prostatic Neoplasms (1) · Pseudomyxoma Peritonei (1)
Adenocarcinoma (8) · Carcinoma (8) · Neoplasms by Histologic Type (8) · Neoplasms, Cystic, Mucinous, and Serous (8) · Neoplasms, Glandular and Epithelial (8) · Neoplasms (7) · Digestive System Diseases (6) · Digestive System Neoplasms (6) · Neoplasms by Site (6) · Gastrointestinal Diseases (5) · Gastrointestinal Neoplasms (5) · Intestinal Diseases (4) · Intestinal Neoplasms (4) · Adnexal Diseases (2) · Cecal Diseases (2)
ACM-001 COVID-19 vaccine (1) · DNA Fingerprinting (1)
M.D. Anderson Cancer Center (2) · Andreana Holowatyj, PhD, MSCI (1) · Apollo Therapeutics Ltd (1) · Brown University (1) · City of Hope Medical Center (1) · Seagen Inc. (1) · University of California, Irvine (1)
United States (8) · Canada (1) · France (1) · Italy (1) · Spain (1) · United Kingdom (1)
Andreana N Holowatyj, PhD, MSCI (1) · Beth Helmink, MD (1) · Khaldoun Almhanna, MD (1) · Maheswari Senthil, MD (1) · Michael White, MD (1) · Sanjay Aggarwal, MD (1) · Suzanne McGoldrick, MD (1)