16 completed, 7 unknown, 6 recruiting, 5 terminated. 15 Phase 2, 7 Not applicable, 6 Phase 1, 6 Phase 3, 1 Early Phase 1.
Follow Allogeneic Stem Cell Transplantation: new trials by email Literature Review of Allogeneic Stem Cell Transplantation trials Research Report on Allogeneic Stem Cell Transplantation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Fibrotic Disease Activity in Cardiopulmonary Disorders Using 18F-Fibroblast Activation Protein Inhibitor (18F-FAPI-74) PET/CT Imaging [18F]FAPI-74, 18F-FAPI-74 PET/CT Imaging - Allogeneic Stem Cell Transplantation, Lung Allograft Transplantation | Phase 3 | Recruiting | National Heart, Lung, and Blood Institute (NHLBI) | 210 | 2026-09-18 | 2026-10-26 |
| Allogeneic HSCT With Low-Dose Post-Transplant Cyclophosphamide for GVHD Prevention Cyclophosphamide (primary intervention for GVHD prophylaxis) - Graft-versus-Host Disease (GVHD), Hematologic Malignancies | Phase 2 | Recruiting | Milton S. Hershey Medical Center | 41 | 2026-03-09 | 2026-04-03 |
| Trial of an Investigational Drug After Rejecting the Relapse of an Allogeneic Transplant CARTemis-1 - Multiple Myeloma, Allogeneic Stem Cell Transplantation | Phase 1 / Phase 2 | Not yet recruiting | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | 25 | 2024-12-30 | 2024-05-14 |
| A Phase I/II Trial to Assess the Efficacy and Toxicity of ASTX727 (Oral Decitabine/Cedazuridine) for the Treatment of Hematological Neoplasms After Allogeneic Stem Cell Transplantation ASTX727, Donor Lymphocyte Infusion - Allogeneic Stem Cell Transplantation | Phase 2 | Withdrawn | M.D. Anderson Cancer Center | 2024-07-01 | 2026-05-15 | |
| CMV-TCIP Directed Letermovir Prophylaxis After Allo-SCT Letermovir, CMV T Cell Immunity Panel (CMV-TCIP), CMV DNA PCR - CMV, Allogeneic Stem Cell Transplantation | Phase 2 | Recruiting | University of California, Irvine | 50 | 2024-06-27 | 2026-07-21 |
| Imaging of Chemotherapy-induced Morphological and Functional Lung Changes in Childhood ALL and HD Low-field magnetic resonance imaging, Cardiopulmonary testing, Pulmonary testing - Acute Lymphoblastic Leukemia, Hodgkin Disease | Not applicable | Completed | University of Erlangen-Nürnberg Medical School | 27 | 2023-10-17 | 2024-12-17 |
| Risk-ADAPTed Conditioning Regimen for Allogeneic Hematopoietic Stem Cell Transplantation Fludarabine, Melphalan, Total Body Irradiation - Allogeneic Hematopoietic Stem Cell Transplantation, Allogeneic Stem Cell Transplantation | Phase 2 | Recruiting | University of California, Irvine | 60 | 2023-09-11 | 2026-02-02 |
| Xylitol BSI Multisite - Reduction of Bloodstream Infections From Oral Organisms in Pediatric Stem Cell Transplant Xylitol, Placebo - Allogeneic Stem Cell Transplantation | Phase 2 | Terminated | Children's Hospital Medical Center, Cincinnati | 256 | 2023-04-04 | 2026-09-28 |
| A Study of Siremadlin Alone and in Combination With Donor Lymphocyte Infusion in Acute Myeloid Leukemia Post-allogeneic Stem Cell Transplant Siremadlin - Acute Myeloid Leukemia, Allogeneic Stem Cell Transplantation | Phase 1 / Phase 2 | Terminated | Novartis Pharmaceuticals | 8 | 2023-02-23 | 2025-05-16 |
| Impact of Aminoglycosides-based Antibiotics Combination and Protective Isolation on Outcomes in Critically-ill Neutropenic Patients With Sepsis: (Combination-Lock01) Aminoglycosides intervention, Lack of protective isolation intervention, No systematic aminoglycosides intervention - standard arm - Sepsis, Septic Shock | Phase 3 | Unknown | Assistance Publique - Hôpitaux de Paris | 340 | 2022-09-01 | 2022-07-05 |
| IFN-γ to Treat Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) That Has Relapsed After Allogeneic Hematopoietic Stem Cell Transplantation IFN-γ (interferon gamma-1b) injection - Myelodysplastic Syndromes, Myeloid Leukemia | Early Phase 1 | Completed | Sawa Ito, MD | 8 | 2021-03-08 | 2025-04-29 |
| Impact of COVID-19 Pandemic on Allogeneic Stem Cell Transplantation Organization : a French Experience Allogeneic Stem Cell Transplantation, SARS-CoV2 Infection | Completed | Central Hospital, Nancy, France | 89 | 2020-03-01 | 2022-07-22 | |
| Immunoevasive Tactics Employed by Myeloid Malignancy After Allogeneic Stem Cell Transplantation blood sample, bone marrow sample - Relapse Leukemia, Allogeneic Stem Cell Transplantation | Not applicable | Unknown | Central Hospital, Nancy, France | 104 | 2019-09-01 | 2019-05-28 |
| Bisantrene for Relapsed /Refractory AML Bisantrene - Acute Myelogenous Leukemia, Allogeneic Stem Cell Transplantation | Phase 2 | Completed | Sheba Medical Center | 10 | 2019-07-18 | 2020-08-07 |
| CLAGE Sequential With Flu-Bu Conditioning for Refractory Acute Leukemia CLAGE-FluBu - Refractory Hematologic Cancer, Allogeneic Stem Cell Transplantation | Phase 2 | Completed | Shanghai Jiao Tong University School of Medicine | 18 | 2018-08-01 | 2023-08-15 |
| Ruxolitinib + Allogeneic Stem Cell Transplantation in AML Ruxolitinib - Acute Myeloid Leukemia, Acute Myeloid Leukemia in Remission | Phase 2 | Active not recruiting | Massachusetts General Hospital | 64 | 2017-11-03 | 2026-03-27 |
| Exercise Prior to Allogeneic Hematologic Stem Cell Transplantation Exercise - Allogeneic Stem Cell Transplantation | Not applicable | Completed | University Health Network, Toronto | 30 | 2014-10-01 | 2019-11-25 |
| Role of Interferon-λ and Vaccine Response influenza A/B vaccine - Vaccine Response Impaired, Allogeneic Stem Cell Transplantation | Completed | University Hospital, Basel, Switzerland | 200 | 2014-09-01 | 2019-10-17 | |
| Immune Monitoring After Allogeneic Hematopoietic Stem Cell Transplantation Allogeneic Stem Cell Transplantation, GVHD | Completed | IRCCS Azienda Ospedaliero-Universitaria di Bologna | 177 | 2014-08-12 | 2023-02-01 | |
| Cognition in Allogeneic Stem Cell Transplanted Patients and Sports Exercise, Control - Allogeneic Stem Cell Transplantation, Exercise Intervention | Not applicable | Unknown | Universitätsklinikum Hamburg-Eppendorf | 80 | 2014-06-01 | 2019-04-30 |
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Hematologic Neoplasms (8) · Neoplasms (5) · Fatigue (4) · Leukemia, Myeloid, Acute (4) · Graft vs Host Disease (3) · Motor Activity (3) · Leukemia (2) · Sepsis (2) · Acute Lung Injury (1) · Bronchiolitis Obliterans (1) · COVID-19 (1) · Cardiovascular Diseases (1) · Cytopenia (1) · Gingivitis (1) · Hematologic Diseases (1)
Hemic and Lymphatic Diseases (17) · Hematologic Diseases (16) · Neoplasms (14) · Neoplasms by Histologic Type (8) · Neoplasms by Site (8) · Pathological Conditions, Signs and Symptoms (6) · Immune System Diseases (5) · Leukemia (5) · Signs and Symptoms (4) · Behavior (3) · Infections (3) · Leukemia, Myeloid (3) · Lung Diseases (3) · Respiratory Tract Diseases (3) · Immunoproliferative Disorders (2)
Exercise (3) · Blood Specimen Collection (2) · Melphalan (2) · Tacrolimus (2) · fludarabine (2) · Antilymphocyte Serum (1) · Blood Chemical Analysis (1) · Bortezomib (1) · Budesonide, Formoterol Fumarate Drug Combination (1) · Cord Blood Stem Cell Transplantation (1) · Cyclophosphamide (1) · Exercise Test (1) · Ganciclovir (1) · Growth Hormone (1) · Human Growth Hormone (1)
Assistance Publique - Hôpitaux de Paris (2) · Center for International Blood and Marrow Transplant Research (2) · Central Hospital, Nancy, France (2) · Charite University, Berlin, Germany (2) · Children's Hospital Medical Center, Cincinnati (2) · University of California, Irvine (2) · Copenhagen University Hospital, Rigshospitalet (1) · Fate Therapeutics (1) · Fundación Pública Andaluza para la gestión de la Investigación en Sevilla (1) · German Cancer Research Center (1) · Grupo Espanol de trasplantes hematopoyeticos y terapia celular (1) · Guangzhou General Hospital of Guangzhou Military Command (1) · H. Kim Lyerly (1) · IRCCS Azienda Ospedaliero-Universitaria di Bologna (1) · Imperial College London (1)
United States (14) · Germany (7) · Spain (3) · China (2) · France (2) · Italy (2) · Switzerland (2) · Austria (1) · Belgium (1) · Canada (1) · Denmark (1) · Israel (1) · United Kingdom (1)
Adrian Egli, PD MD (1) · Anthony F Suffredini, M.D. (1) · Axel Karow, MD (1) · Betul Oran, MD (1) · Christopher Dandoy, MD, MSc (1) · Corey Cutler, MD, MPH, FRCP(C) (1) · Dreger Peter, Prof. MD (1) · Duarte R Palomino, MD (1) · Ferdinand Knieling, MD (1) · Fernando Dimeo, MD (1) · Gabriell Hobbs, MD (1) · H. Kim Lyerly, M.D. (1) · Hermann Einsele, Prof. Dr. (1) · Igor Wolfgang Blau, Dr. (1) · Jeff Lipton, MD, PhD (1)
PMID 23996087, PMID 24593273, PMID 26345187, PMID 31830234, PMID 34152703, PMID 34415049, PMID 39794666, PMID 40106768, PMID 40488780
1UG3DE030401-01 (1)