8 completed, 1 terminated, 1 unknown, 1 withdrawn. 6 Phase 2, 2 Not applicable, 1 Early Phase 1, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Completed 6 |
| Not applicable | 2 | Terminated 1, Unknown 1 |
| Early Phase 1 | 1 | Completed 1 |
| Phase 1 | 1 | Completed 1 |
Follow Acne Inversa: new trials by email Literature Review of Acne Inversa trials Research Report on Acne Inversa
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Anifrolumab for Hidradenitis Suppurativa Anifrolumab - Hidradenitis Suppurativa, Acne Inversa | Phase 2 | Completed | University of North Carolina, Chapel Hill | 15 | 2024-06-21 | 2026-08-03 |
| Molecular Characteristics of Brodalumab in Hidradenitis Suppurativa Brodalumab - Hidradenitis Suppurativa, Acne Inversa | Early Phase 1 | Completed | Rockefeller University | 4 | 2021-08-05 | 2022-07-27 |
| To Assess the Efficacy and Safety of INCB054707 in Participants With Hidradenitis Suppurativa INCB054707, Placebo - Hidradenitis Suppurativa, Acne Inversa | Phase 2 | Completed | Incyte Corporation | 209 | 2020-08-25 | 2025-08-12 |
| A Pilot Study to Explore the Role of Gut Flora in Acne No intervention - Acne, Acne Vulgaris | Withdrawn | ProgenaBiome | 2020-03-02 | 2025-06-05 | ||
| A Study to Evaluate the Safety and Efficacy of PF-06650833, PF-06700841, and PF 06826647 in Adults With Hidradenitis Suppurativa PF-06650833, PF-06700841, PF-06826647 - Acne Inversa | Phase 2 | Completed | Pfizer | 194 | 2019-12-02 | 2023-06-15 |
| A Study to Evaluate the Efficacy, Safety and Tolerability of Bermekimab in Patients With Hidradenitis Suppurativa bermekimab, placebo - Hidradenitis Suppurativa, Acne Inversa | Phase 2 | Completed | Janssen Research & Development, LLC | 153 | 2019-09-16 | 2023-07-27 |
| Evaluation of Safety and Efficacy of Avacopan in Subjects With Moderate to Severe Hidradenitis Suppurativa (AURORA) Avacopan, Placebo - Hidradenitis Suppurativa, Acne Inversa | Phase 2 | Completed | Amgen | 435 | 2018-12-21 | 2025-03-17 |
| Hydroxychloroquine for the Treatment of Hidradenitis Suppurativa Hydroxychloroquine - Hidradenitis Suppurativa, Hidradenitis | Phase 1 / Phase 2 | Completed | Elena Gonzalez Brant, MD | 17 | 2017-09-28 | 2020-04-02 |
| Microwave Ablation in Mild Axillary Hidradenitis Suppurativa Microwave ablation - Hidradenitis Suppurativa, Acne Inversa | Not applicable | Terminated | M.B.A. van Doorn | 9 | 2017-09-01 | 2018-06-25 |
| Intense Pulsed Light Therapy for Hidrosadenitis Suppurativa IPL laser, No sham treatment - Hidradenitis Suppurativa, Acne Inversa | Not applicable | Unknown | Zealand University Hospital | 20 | 2017-08-07 | 2017-06-29 |
| Wound Etiology and Healing Study Wounds, Hidradenitis Suppurativa | Completed | George Washington University | 743 | 2011-05-01 | 2022-07-27 |
Hidradenitis Suppurativa (11) · Hidradenitis (3) · Abscess (1) · Acne Conglobata (1) · Acne Keloid (1) · Acne Vulgaris (1) · Furunculosis (1) · Rosacea (1) · Skin Diseases (1) · Wounds and Injuries (1)
Bacterial Infections (11) · Bacterial Infections and Mycoses (11) · Infections (11) · Skin Diseases, Bacterial (11) · Skin Diseases, Infectious (11) · Skin and Connective Tissue Diseases (11) · Suppuration (11) · Sweat Gland Diseases (11) · Skin Diseases (10) · Hidradenitis (8) · Acneiform Eruptions (1) · Animal Diseases (1) · Collagen Diseases (1) · Connective Tissue Diseases (1) · Fish Diseases (1)
1-(((2S,3S,4S)-3-ethyl-4-fluoro-5-oxopyrrolidin-2-yl)methoxy)-7-methoxyisoquinoline-6-carboxamide (1) · Hydroxychloroquine (1) · PF-06700841 (1) · anifrolumab (1) · avacopan (1) · bermekimab (1) · brodalumab (1) · ropsacitinib (1)
Amgen (1) · Elena Gonzalez Brant, MD (1) · George Washington University (1) · Incyte Corporation (1) · Janssen Research & Development, LLC (1) · M.B.A. van Doorn (1) · Pfizer (1) · ProgenaBiome (1) · Rockefeller University (1) · University of North Carolina, Chapel Hill (1) · Zealand University Hospital (1)
United States (9) · Canada (2) · Australia (1) · Denmark (1) · France (1) · Germany (1) · Netherlands (1) · Poland (1) · Spain (1)
Christopher Sayed, MD (1) · Elena M Gonzalez Brant, MD (1) · Errol Prens, MD, PhD (1) · Sabine Hazan, MD (1) · Victoria K Shanmugam, MD (1) · Yael Renert-Yuval, MD (1)
KL2RR031974 (1), R01NR013888 (1), UL1RR031975 (1)