A Pilot Study to Explore the Role of Gut Flora in Acne

The goal of this Research Study is to better understand how the genetic information in subject's microbiome correlates to acne.

• No intervention (Other): There is no intervention for this study.

Primary outcomes

• Correlation of Microbiome to Disease via Relative Abundance Found in Microbiome Sequencing [Three years]: Relative abundance of bacterial classes within taxonomic phyla and, more broadly, within their domain will be analyzed by sequencing the gut microbiome. These data will then be categorized with acne.

Sex: All

Inclusion Criteria:

1. Signed informed consent, demonstrating that the patient understands the procedures required for the study and the purpose of the study

   a. May be signed by parent or legal guardian in the case of minor or adult unable to provide consent
2. Male or female of all ages.
3. Diagnosis of acne by a physician

Exclusion Criteria:

1. Refusal to sign informed consent form
2. History of bariatric surgery, total colectomy with ileorectal anastomosis or proctocolectomy.
3. Postoperative stoma, ostomy, or ileoanal pouch
4. Participation in any experimental drug protocol within the past 12 weeks
5. Treatment with total parenteral nutrition

• Sabine Hazan, MD, Principal investigator, ProgenaBiome