Most Influential NATURE Papers (2025-09 Version)
Nature is a British weekly scientific journal founded and based in London, England. As a multidisciplinary publication, Nature features peer-reviewed research from a variety of academic disciplines, mainly in science, technology, and the natural sciences. Paper Digest Team analyze all papers published on NATURE in the past years, and presents the 10 most influential papers for each year (based on when the paper became available online). This ranking list is automatically constructed based upon citations from both research papers and granted patents, and will be frequently updated to reflect the most recent changes. To find the most influential papers from other conferences/journals, visit Best Paper Digest page. Note: the most influential papers may or may not include the papers that won the best paper awards. (Version: 2025-09)
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TABLE 1: Most Influential NATURE Papers (2025-09 Version)
| Year | Rank | Paper | Author(s) |
|---|---|---|---|
| 2025 | 1 | Accurate Predictions on Small Data with A Tabular Foundation Model IF:4 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Tabular data, spreadsheets organized in rows and columns, are ubiquitous across scientific fields, from biomedicine to particle physics to economics and climate science . The … |
NOAH HOLLMANN et. al. |
| 2025 | 2 | A Generative Model for Inorganic Materials Design IF:4 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: The design of functional materials with desired properties is essential in driving technological advances in areas such as energy storage, catalysis and carbon capture . … |
CLAUDIO ZENI et. al. |
| 2025 | 3 | Distributed Quantum Computing Across An Optical Network Link IF:3 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Distributed quantum computing (DQC) combines the computing power of multiple networked quantum processing modules, ideally enabling the execution of large quantum circuits without … |
D MAIN et. al. |
| 2025 | 4 | A Foundation Model for The Earth System IF:3 Related Papers Related Patents Related Grants Related Venues Related Experts View Highlight: Here we introduce Aurora, a large-scale foundation model trained on more than one million hours of diverse geophysical data. |
CRISTIAN BODNAR et. al. |
| 2025 | 5 | A Vision-language Foundation Model for Precision Oncology IF:3 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Clinical decision-making is driven by multimodal data, including clinical notes and pathological characteristics. Artificial intelligence approaches that can effectively integrate … |
JINXI XIANG et. al. |
| 2025 | 6 | Signatures of Chiral Superconductivity in Rhombohedral Graphene IF:3 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Chiral superconductors are unconventional superconducting states that break time-reversal symmetry spontaneously and typically feature Cooper pairing at non-zero angular momentum. … |
TONGHANG HAN et. al. |
| 2025 | 7 | Interferometric Single-shot Parity Measurement in InAs-Al Hybrid Devices IF:3 Related Papers Related Patents Related Grants Related Venues Related Experts View Highlight: Here we introduce a device architecture that is compatible with future tests of fusion rules. |
MORTEZA AGHAEE et. al. |
| 2025 | 8 | Towards Conversational Diagnostic Artificial Intelligence IF:3 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: At the heart of medicine lies physician-patient dialogue, where skillful history-taking enables effective diagnosis, management and enduring trust . Artificial intelligence (AI) … |
TAO TU et. al. |
| 2025 | 9 | Interferometric Single-shot Parity Measurement in InAs–Al Hybrid Devices IF:3 Related Papers Related Patents Related Grants Related Venues Related Experts View |
M. AGHAEE et. al. |
| 2025 | 10 | Scaling and Networking A Modular Photonic Quantum Computer IF:3 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Photonics offers a promising platform for quantum computing , owing to the availability of chip integration for mass-manufacturable modules, fibre optics for networking and … |
H AGHAEE RAD et. al. |
| 2024 | 1 | Accurate Structure Prediction of Biomolecular Interactions with AlphaFold 3 IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: The introduction of AlphaFold 2 has spurred a revolution in modelling the structure of proteins and their interactions, enabling a huge range of applications in protein modelling … |
JOSH ABRAMSON et. al. |
| 2024 | 2 | Detecting Hallucinations in Large Language Models Using Semantic Entropy IF:6 Related Papers Related Patents Related Grants Related Venues Related Experts View Highlight: Here we develop new methods grounded in statistics, proposing entropy-based uncertainty estimators for LLMs to detect a subset of hallucinations-confabulations-which are arbitrary and incorrect generations. |
Sebastian Farquhar; Jannik Kossen; Lorenz Kuhn; Yarin Gal; |
| 2024 | 3 | Solving Olympiad Geometry Without Human Demonstrations IF:6 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Proving mathematical theorems at the olympiad level represents a notable milestone in human-level automated reasoning , owing to their reputed difficulty among the world’s best … |
Trieu H Trinh; Yuhuai Wu; Quoc V Le; He He; Thang Luong; |
| 2024 | 4 | Buried Interface Molecular Hybrid for Inverted Perovskite Solar Cells IF:6 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Perovskite solar cells with an inverted architecture provide a key pathway for commercializing this emerging photovoltaic technology because of the better power conversion … |
SANWAN LIU et. al. |
| 2024 | 5 | High-threshold and Low-overhead Fault-tolerant Quantum Memory IF:6 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: The accumulation of physical errors prevents the execution of large-scale algorithms in current quantum computers. Quantum error correction promises a solution by encoding k … |
SERGEY BRAVYI et. al. |
| 2024 | 6 | Fractional Quantum Anomalous Hall Effect in Multilayer Graphene IF:6 Related Papers Related Patents Related Grants Related Venues Related Experts View Highlight: Here we report the observation of integer and fractional QAH effects in a rhombohedral pentalayer graphene-hBN moiré superlattice. |
ZHENGGUANG LU et. al. |
| 2024 | 7 | A Whole-slide Foundation Model for Digital Pathology from Real-world Data IF:6 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Digital pathology poses unique computational challenges, as a standard gigapixel slide may comprise tens of thousands of image tiles . Prior models have often resorted to … |
HANWEN XU et. al. |
| 2024 | 8 | Altermagnetic Lifting of Kramers Spin Degeneracy IF:6 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Lifted Kramers spin degeneracy (LKSD) has been among the central topics of condensed-matter physics since the dawn of the band theory of solids . It underpins established … |
J KREMPASKÝ et. al. |
| 2024 | 9 | AI Models Collapse When Trained on Recursively Generated Data IF:6 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Stable diffusion revolutionized image creation from descriptive text. GPT-2 (ref. ), GPT-3(.5) (ref. ) and GPT-4 (ref. ) demonstrated high performance across a variety of … |
ILIA SHUMAILOV et. al. |
| 2024 | 10 | Artificial Intelligence and Illusions of Understanding in Scientific Research IF:5 Related Papers Related Patents Related Grants Related Venues Related Experts View Highlight: Scientists are enthusiastically imagining ways in which artificial intelligence (AI) tools might improve research. |
Lisa Messeri; M J Crockett; |
| 2023 | 1 | Large Language Models Encode Clinical Knowledge IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Large language models (LLMs) have demonstrated impressive capabilities, but the bar for clinical applications is high. Attempts to assess the clinical knowledge of models … |
KARAN SINGHAL et. al. |
| 2023 | 2 | FinnGen Provides Genetic Insights from A Well-phenotyped Isolated Population IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Population isolates such as those in Finland benefit genetic research because deleterious alleles are often concentrated on a small number of low-frequency variants (0.1% ≤ minor … |
MITJA I KURKI et. al. |
| 2023 | 3 | Controlled Growth of Perovskite Layers with Volatile Alkylammonium Chlorides IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Controlling the crystallinity and surface morphology of perovskite layers by methods such as solvent engineering and methylammonium chloride addition is an effective strategy for … |
JAEWANG PARK et. al. |
| 2023 | 4 | ChatGPT: Five Priorities for Research IF:8 Related Papers Related Patents Related Grants Related Venues Related Experts View |
Eva A M van Dis; Johan Bollen; Willem Zuidema; Robert van Rooij; Claudi L Bockting; |
| 2023 | 5 | Foundation Models for Generalist Medical Artificial Intelligence IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: The exceptionally rapid development of highly flexible, reusable artificial intelligence (AI) models is likely to usher in newfound capabilities in medicine. We propose a new … |
MICHAEL MOOR et. al. |
| 2023 | 6 | Scientific Discovery in The Age of Artificial Intelligence IF:7 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Artificial intelligence (AI) is being increasingly integrated into scientific discovery to augment and accelerate research, helping scientists to generate hypotheses, design … |
HANCHEN WANG et. al. |
| 2023 | 7 | Logical Quantum Processor Based on Reconfigurable Atom Arrays IF:7 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Suppressing errors is the central challenge for useful quantum computing , requiring quantum error correction (QEC) for large-scale processing. However, the overhead in the … |
DOLEV BLUVSTEIN et. al. |
| 2023 | 8 | Evidence for The Utility of Quantum Computing Before Fault Tolerance IF:7 Related Papers Related Patents Related Grants Related Venues Related Experts View Highlight: Here we report experiments on a noisy 127-qubit processor and demonstrate the measurement of accurate expectation values for circuit volumes at a scale beyond brute-force classical computation. We argue that this represents evidence for the utility of quantum computing in a pre-fault-tolerant era. |
YOUNGSEOK KIM et. al. |
| 2023 | 9 | De Novo Design of Protein Structure and Function with RFdiffusion IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: There has been considerable recent progress in designing new proteins using deep-learning methods . Despite this progress, a general deep-learning framework for protein design … |
JOSEPH L WATSON et. al. |
| 2023 | 10 | Accurate Medium-range Global Weather Forecasting with 3D Neural Networks IF:7 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Weather forecasting is important for science and society. At present, the most accurate forecast system is the numerical weather prediction (NWP) method, which represents … |
KAIFENG BI et. al. |
| 2022 | 1 | Mapping Genomic Loci Implicates Genes and Synaptic Biology in Schizophrenia IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Schizophrenia has a heritability of 60-80% , much of which is attributable to common risk alleles. Here, in a two-stage genome-wide association study of up to 76,755 individuals … |
VASSILY TRUBETSKOY et. al. |
| 2022 | 2 | Rapid Epidemic Expansion of The SARS-CoV-2 Omicron Variant in Southern Africa IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: The SARS-CoV-2 epidemic in southern Africa has been characterized by three distinct waves. The first was associated with a mix of SARS-CoV-2 lineages, while the second and third … |
RAQUEL VIANA et. al. |
| 2022 | 3 | Reproducible Brain-wide Association Studies Require Thousands of Individuals IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Magnetic resonance imaging (MRI) has transformed our understanding of the human brain through well-replicated mapping of abilities to specific structures (for example, lesion … |
SCOTT MAREK et. al. |
| 2022 | 4 | SARS-CoV-2 Is Associated with Changes in Brain Structure in UK Biobank IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: There is strong evidence of brain-related abnormalities in COVID-19 . However, it remains unknown whether the impact of SARS-CoV-2 infection can be detected in milder cases, and … |
GWENAËLLE DOUAUD et. al. |
| 2022 | 5 | BA.2.12.1, BA.4 and BA.5 Escape Antibodies Elicited By Omicron Infection IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineages BA.2.12.1, BA.4 and BA.5 exhibit higher transmissibility than the BA.2 lineage . The receptor … |
YUNLONG CAO et. al. |
| 2022 | 6 | Brain Charts for The Human Lifespan IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Over the past few decades, neuroimaging has become a ubiquitous tool in basic research and clinical studies of the human brain. However, no reference standards currently exist to … |
R A I BETHLEHEM et. al. |
| 2022 | 7 | Quantum Computational Advantage with A Programmable Photonic Processor IF:7 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: A quantum computer attains computational advantage when outperforming the best classical computers running the best-known algorithms on well-defined tasks. No photonic machine … |
LARS S MADSEN et. al. |
| 2022 | 8 | Altered TMPRSS2 Usage By SARS-CoV-2 Omicron Impacts Infectivity and Fusogenicity IF:7 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: The SARS-CoV-2 Omicron BA.1 variant emerged in 2021 and has multiple mutations in its spike protein . Here we show that the spike protein of Omicron has a higher affinity for ACE2 … |
BO MENG et. al. |
| 2022 | 9 | Altered TMPRSS2 Usage By SARS-CoV-2 Omicron Impacts Tropism and Fusogenicity IF:7 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: The SARS-CoV-2 Omicron BA.1 variant emerged in 20211 and bears multiple spike mutations2. Here we show that Omicron spike has higher affinity for ACE2 compared to Delta as well as … |
BO MENG et. al. |
| 2022 | 10 | Antibody Evasion Properties of SARS-CoV-2 Omicron Sublineages IF:7 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: The identification of the Omicron (B.1.1.529.1 or BA.1) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Botswana in November 2021 immediately caused … |
SHO IKETANI et. al. |
| 2021 | 1 | Highly Accurate Protein Structure Prediction with AlphaFold IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Proteins are essential to life, and understanding their structure can facilitate a mechanistic understanding of their function. Through an enormous experimental effort , the … |
JOHN JUMPER et. al. |
| 2021 | 2 | Highly Accurate Protein Structure Prediction for The Human Proteome IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Protein structures can provide invaluable information, both for reasoning about biological processes and for enabling interventions such as structure-based drug development or … |
KATHRYN TUNYASUVUNAKOOL et. al. |
| 2021 | 3 | Perovskite Solar Cells with Atomically Coherent Interlayers on SnO2 Electrodes IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: In perovskite solar cells, the interfaces between the perovskite and charge-transporting layers contain high concentrations of defects (about 100 times that within the perovskite … |
HANUL MIN et. al. |
| 2021 | 4 | Pseudo-halide Anion Engineering for Α-FAPbI3 Perovskite Solar Cells IF:8 Related Papers Related Patents Related Grants Related Venues Related Experts View |
JAEKI JEONG et. al. |
| 2021 | 5 | Efficient Perovskite Solar Cells Via Improved Carrier Management IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Metal halide perovskite solar cells (PSCs) are an emerging photovoltaic technology with the potential to disrupt the mature silicon solar cell market. Great improvements in device … |
JASON J YOO et. al. |
| 2021 | 6 | Towards Complete and Error-free Genome Assemblies of All Vertebrate Species IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: High-quality and complete reference genome assemblies are fundamental for the application of genomics to biology, disease, and biodiversity conservation. However, such assemblies … |
ARANG RHIE et. al. |
| 2021 | 7 | Reduced Sensitivity of SARS-CoV-2 Variant Delta to Antibody Neutralization IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: The SARS-CoV-2 B.1.617 lineage was identified in October 2020 in India . Since then, it has become dominant in some regions of India and in the UK, and has spread to many other … |
DELPHINE PLANAS et. al. |
| 2021 | 8 | Designing The Next Generation of Proton-exchange Membrane Fuel Cells IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: With the rapid growth and development of proton-exchange membrane fuel cell (PEMFC) technology, there has been increasing demand for clean and sustainable global energy … |
KUI JIAO et. al. |
| 2021 | 9 | The Changing Landscape of Atherosclerosis IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Emerging evidence has spurred a considerable evolution of concepts relating to atherosclerosis, and has called into question many previous notions. Here I review this evidence, … |
Peter Libby; |
| 2021 | 10 | Omicron Escapes The Majority of Existing SARS-CoV-2 Neutralizing Antibodies IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: The SARS-CoV-2 B.1.1.529 (Omicron) variant contains 15 mutations of the receptor-binding domain (RBD). How Omicron evades RBD-targeted neutralizing antibodies requires immediate … |
YUNLONG CAO et. al. |
| 2020 | 1 | A Pneumonia Outbreak Associated with A New Coronavirus of Probable Bat Origin IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Since the outbreak of severe acute respiratory syndrome (SARS) 18 years ago, a large number of SARS-related coronaviruses (SARSr-CoVs) have been discovered in their natural … |
PENG ZHOU et. al. |
| 2020 | 2 | Array Programming with NumPy IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Array programming provides a powerful, compact and expressive syntax for accessing, manipulating and operating on data in vectors, matrices and higher-dimensional arrays. NumPy is … |
CHARLES R HARRIS et. al. |
| 2020 | 3 | A New Coronavirus Associated with Human Respiratory Disease in China IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Emerging infectious diseases, such as severe acute respiratory syndrome (SARS) and Zika virus disease, present a major threat to public health . Despite intense research efforts, … |
FAN WU et. al. |
| 2020 | 4 | The Mutational Constraint Spectrum Quantified from Variation in 141,456 Humans IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Genetic variants that inactivate protein-coding genes are a powerful source of information about the phenotypic consequences of gene disruption: genes that are crucial for the … |
KONRAD J KARCZEWSKI et. al. |
| 2020 | 5 | Virological Assessment of Hospitalized Patients with COVID-2019 IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Coronavirus disease 2019 (COVID-19) is an acute infection of the respiratory tract that emerged in late 2019 . Initial outbreaks in China involved 13.8% of cases with severe … |
ROMAN WÖLFEL et. al. |
| 2020 | 6 | Structure of The SARS-CoV-2 Spike Receptor-binding Domain Bound to The ACE2 Receptor IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: A new and highly pathogenic coronavirus (severe acute respiratory syndrome coronavirus-2, SARS-CoV-2) caused an outbreak in Wuhan city, Hubei province, China, starting from … |
JUN LAN et. al. |
| 2020 | 7 | OpenSAFELY: Factors Associated with COVID-19 Death in 17 Million Patients IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: COVID-19 has rapidly affected mortality worldwide 1 . There is unprecedented urgency to understand who is most at risk of severe outcomes, requiring new approaches for timely … |
ELIZABETH J WILLIAMSON et. al. |
| 2020 | 8 | Factors Associated with COVID-19-related Death Using OpenSAFELY IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Coronavirus disease 2019 (COVID-19) has rapidly affected mortality worldwide . There is unprecedented urgency to understand who is most at risk of severe outcomes, and this … |
ELIZABETH J WILLIAMSON et. al. |
| 2020 | 9 | A SARS-CoV-2 Protein Interaction Map Reveals Targets for Drug-Repurposing IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: A newly described coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is the causative agent of coronavirus disease 2019 (COVID-19), has infected … |
DAVID E. GORDON et. al. |
| 2020 | 10 | Structural Basis of Receptor Recognition By SARS-CoV-2 IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: A novel severe acute respiratory syndrome (SARS)-like coronavirus (SARS-CoV-2) recently emerged and is rapidly spreading in humans, causing COVID-19 . A key to tackling this … |
JIAN SHANG et. al. |
| 2019 | 1 | Quantum Supremacy Using A Programmable Superconducting Processor IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: The promise of quantum computers is that certain computational tasks might be executed exponentially faster on a quantum processor than on a classical processor . A fundamental … |
FRANK ARUTE et. al. |
| 2019 | 2 | Grandmaster Level in StarCraft II Using Multi-agent Reinforcement Learning IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Many real-world applications require artificial agents to compete and coordinate with other agents in complex environments. As a stepping stone to this goal, the domain of … |
ORIOL VINYALS et. al. |
| 2019 | 3 | Deep Learning And Process Understanding For Data-driven Earth System Science IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Machine learning approaches are increasingly used to extract patterns and insights from the ever-increasing stream of geospatial data, but current approaches may not be optimal … |
MARKUS REICHSTEIN et. al. |
| 2019 | 4 | Search-and-replace Genome Editing Without Double-strand Breaks or Donor DNA IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Most genetic variants that contribute to disease are challenging to correct efficiently and without excess byproducts . Here we describe prime editing, a versatile and precise … |
ANDREW V ANZALONE et. al. |
| 2019 | 5 | The Single Cell Transcriptional Landscape of Mammalian Organogenesis IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Mammalian organogenesis is a remarkable process. Within a short timeframe, the cells of the three germ layers transform into an embryo that includes most of the major internal and … |
JUNYUE CAO et. al. |
| 2019 | 6 | The CoQ Oxidoreductase FSP1 Acts in Parallel to GPX4 to Inhibit Ferroptosis IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Ferroptosis is a form of regulated cell death that is caused by the iron-dependent peroxidation of lipids1,2. The glutathione-dependent lipid hydroperoxidase glutathione … |
KIRILL BERSUKER et. al. |
| 2019 | 7 | Next-generation Characterization of The Cancer Cell Line Encyclopedia IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Large panels of comprehensively characterized human cancer models, including the Cancer Cell Line Encyclopedia (CCLE), have provided a rigorous framework with which to study … |
MAHMOUD GHANDI et. al. |
| 2019 | 8 | Recycling Lithium-ion Batteries from Electric Vehicles IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Rapid growth in the market for electric vehicles is imperative, to meet global targets for reducing greenhouse gas emissions, to improve air quality in urban centres and to meet … |
GAVIN HARPER et. al. |
| 2019 | 9 | Metabolic Regulation of Gene Expression By Histone Lactylation IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: The Warburg effect, which originally described increased production of lactate in cancer, is associated with diverse cellular processes such as angiogenesis, hypoxia, polarization … |
DI ZHANG et. al. |
| 2019 | 10 | FSP1 Is A Glutathione-independent Ferroptosis Suppressor IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Ferroptosis is an iron-dependent form of necrotic cell death marked by oxidative damage to phospholipids . To date, ferroptosis has been thought to be controlled only by the … |
SEBASTIAN DOLL et. al. |
| 2018 | 1 | Unconventional Superconductivity In Magic-angle Graphene Superlattices IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: The behaviour of strongly correlated materials, and in particular unconventional superconductors, has been studied extensively for decades, but is still not well understood. This … |
YUAN CAO et. al. |
| 2018 | 2 | The UK Biobank Resource with Deep Phenotyping and Genomic Data IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: The UK Biobank project is a prospective cohort study with deep genetic and phenotypic data collected on approximately 500,000 individuals from across the United Kingdom, aged … |
CLARE BYCROFT et. al. |
| 2018 | 3 | Correlated Insulator Behaviour At Half-filling In Magic-angle Graphene Superlattices IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: A van der Waals heterostructure is a type of metamaterial that consists of vertically stacked two-dimensional building blocks held together by the van der Waals forces between the … |
YUAN CAO et. al. |
| 2018 | 4 | TGF-β Attenuates Tumour Response to PD-L1 Blockade By Contributing to Exclusion of T Cells IF:8 Related Papers Related Patents Related Grants Related Venues Related Experts View |
S. MARIATHASAN et. al. |
| 2018 | 5 | Machine Learning for Molecular and Materials Science IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Here we summarize recent progress in machine learning for the chemical sciences. We outline machine-learning techniques that are suitable for addressing research questions in this … |
Keith T Butler; Daniel W Davies; Hugh Cartwright; Olexandr Isayev; Aron Walsh; |
| 2018 | 6 | RNA Velocity of Single Cells IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: RNA abundance is a powerful indicator of the state of individual cells. Single-cell RNA sequencing can reveal RNA abundance with high quantitative accuracy, sensitivity and … |
GIOELE LA MANNO et. al. |
| 2018 | 7 | Perovskite Light-emitting Diodes With External Quantum Efficiency Exceeding 20 Per Cent IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Metal halide perovskite materials are an emerging class of solution-processable semiconductors with considerable potential for use in optoelectronic devices . For example, … |
KEBIN LIN et. al. |
| 2018 | 8 | Options for Keeping The Food System Within Environmental Limits IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: The food system is a major driver of climate change, changes in land use, depletion of freshwater resources, and pollution of aquatic and terrestrial ecosystems through excessive … |
MARCO SPRINGMANN et. al. |
| 2018 | 9 | Exosomal PD-L1 Contributes to Immunosuppression and Is Associated with Anti-PD-1 Response IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Tumour cells evade immune surveillance by upregulating the surface expression of programmed death-ligand 1 (PD-L1), which interacts with programmed death-1 (PD-1) receptor on T … |
GANG CHEN et. al. |
| 2018 | 10 | Environment Dominates Over Host Genetics In Shaping Human Gut Microbiota IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Human gut microbiome composition is shaped by multiple factors but the relative contribution of host genetics remains elusive. Here we examine genotype and microbiome data from … |
DAPHNA ROTHSCHILD et. al. |
| 2017 | 1 | Dermatologist-level Classification of Skin Cancer with Deep Neural Networks IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Skin cancer, the most common human malignancy, is primarily diagnosed visually, beginning with an initial clinical screening and followed potentially by dermoscopic analysis, a … |
ANDRE ESTEVA et. al. |
| 2017 | 2 | Mastering The Game Of Go Without Human Knowledge IF:10 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: A long-standing goal of artificial intelligence is an algorithm that learns, tabula rasa, superhuman proficiency in challenging domains. Recently, AlphaGo became the first program … |
DAVID SILVER et. al. |
| 2017 | 3 | A Communal Catalogue Reveals Earth’s Multiscale Microbial Diversity IF:8 Related Papers Related Patents Related Grants Related Venues Related Experts View |
NICOLE M. GAUDELLI et. al. |
| 2017 | 4 | Layer-dependent Ferromagnetism In A Van Der Waals Crystal Down To The Monolayer Limit IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Since the discovery of graphene, the family of two-dimensional materials has grown, displaying a broad range of electronic properties. Recent additions include semiconductors with … |
BEVIN HUANG et. al. |
| 2017 | 5 | Elements of Cancer Immunity and The Cancer–immune Set Point IF:8 Related Papers Related Patents Related Grants Related Venues Related Experts View |
Daniel S. Chen; I. Mellman; |
| 2017 | 6 | Discovery Of Intrinsic Ferromagnetism In Two-dimensional Van Der Waals Crystals IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: The realization of long-range ferromagnetic order in two-dimensional van der Waals crystals, combined with their rich electronic and optical properties, could lead to new … |
CHENG GONG et. al. |
| 2017 | 7 | The Biology And Management Of Non-small Cell Lung Cancer IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Important advancements in the treatment of non-small cell lung cancer (NSCLC) have been achieved over the past two decades, increasing our understanding of the disease biology and … |
Roy S Herbst; Daniel Morgensztern; Chris Boshoff; |
| 2017 | 8 | Hardware-efficient Variational Quantum Eigensolver For Small Molecules And Quantum Magnets IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Quantum computers can be used to address electronic-structure problems and problems in materials science and condensed matter physics that can be formulated as interacting … |
ABHINAV KANDALA et. al. |
| 2017 | 9 | An Immunogenic Personal Neoantigen Vaccine for Patients with Melanoma IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Effective anti-tumour immunity in humans has been associated with the presence of T cells directed at cancer neoantigens, a class of HLA-bound peptides that arise from … |
PATRICK A OTT et. al. |
| 2017 | 10 | Chemotherapy Drugs Induce Pyroptosis Through Caspase-3 Cleavage of A Gasdermin IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Pyroptosis is a form of cell death that is critical for immunity. It can be induced by the canonical caspase-1 inflammasomes or by activation of caspase-4, -5 and -11 by cytosolic … |
YUPENG WANG et. al. |
| 2016 | 1 | Programmable Editing of A Target Base in Genomic DNA Without Double-stranded DNA Cleavage IF:10 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Current genome-editing technologies introduce double-stranded (ds) DNA breaks at a target locus as the first step to gene correction. Although most genetic diseases arise from … |
Alexis C Komor; Yongjoo B Kim; Michael S Packer; John A Zuris; David R Liu; |
| 2016 | 2 | A Multi-modal Parcellation of Human Cerebral Cortex IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Understanding the amazingly complex human cerebral cortex requires a map (or parcellation) of its major subdivisions, known as cortical areas. Making an accurate areal map has … |
MATTHEW F GLASSER et. al. |
| 2016 | 3 | Elements Of Cancer Immunity And The Cancer-immune Set Point IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Immunotherapy is proving to be an effective therapeutic approach in a variety of cancers. But despite the clinical success of antibodies against the immune regulators CTLA4 and … |
Daniel S Chen; Ira Mellman; |
| 2016 | 4 | High-resolution Mapping Of Global Surface Water And Its Long-term Changes IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: The location and persistence of surface water (inland and coastal) is both affected by climate and human activity and affects climate, biological diversity and human wellbeing. … |
Jean-François Pekel; Andrew Cottam; Noel Gorelick; Alan S Belward; |
| 2016 | 5 | Genetic Effects on Gene Expression Across Human Tissues IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Characterization of the molecular function of the human genome and its variation across individuals is essential for identifying the cellular mechanisms that underlie human … |
Alexis Battle; Christopher D Brown; Barbara E Engelhardt; Stephen B Montgomery; |
| 2016 | 6 | Metastable High-entropy Dual-phase Alloys Overcome The Strength-ductility Trade-off IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Metals have been mankind’s most essential materials for thousands of years; however, their use is affected by ecological and economical concerns. Alloys with higher strength and … |
Zhiming Li; Konda Gokuldoss Pradeep; Yun Deng; Dierk Raabe; Cemal Cem Tasan; |
| 2016 | 7 | Metastable High-entropy Dual-phase Alloys Overcome The Strength–ductility Trade-off IF:8 Related Papers Related Patents Related Grants Related Venues Related Experts View |
Zhiming Li; K. Pradeep; Yun-jiao Deng; D. Raabe; C. Tasan; |
| 2016 | 8 | Seven Chemical Separations To Change The World IF:9 Related Papers Related Patents Related Grants Related Venues Related Experts View |
David S Sholl; Ryan P Lively; |
| 2016 | 9 | 1,500 Scientists Lift The Lid on Reproducibility IF:8 Related Papers Related Patents Related Grants Related Venues Related Experts View |
Monya Baker; |
| 2016 | 10 | Genomic Analyses Identify Molecular Subtypes of Pancreatic Cancer IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Integrated genomic analysis of 456 pancreatic ductal adenocarcinomas identified 32 recurrently mutated genes that aggregate into 10 pathways: KRAS, TGF-β, WNT, NOTCH, ROBO/SLIT … |
PETER BAILEY et. al. |
| 2015 | 1 | Deep Learning IF:10 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Deep learning allows computational models that are composed of multiple processing layers to learn representations of data with multiple levels of abstraction. These methods have … |
Yann LeCun; Yoshua Bengio; Geoffrey Hinton; |
| 2015 | 2 | Mastering The Game Of Go With Deep Neural Networks And Tree Search IF:10 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: The game of Go has long been viewed as the most challenging of classic games for artificial intelligence owing to its enormous search space and the difficulty of evaluating board … |
DAVID SILVER et. al. |
| 2015 | 3 | A Global Reference for Human Genetic Variation IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: The 1000 Genomes Project set out to provide a comprehensive description of common human genetic variation by applying whole-genome sequencing to a diverse set of individuals from … |
ADAM AUTON et. al. |
| 2015 | 4 | Compositional Engineering Of Perovskite Materials For High-performance Solar Cells IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Of the many materials and methodologies aimed at producing low-cost, efficient photovoltaic cells, inorganic-organic lead halide perovskite materials appear particularly promising … |
NAM JOONG JEON et. al. |
| 2015 | 5 | Cleavage of GSDMD By Inflammatory Caspases Determines Pyroptotic Cell Death IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Inflammatory caspases (caspase-1, -4, -5 and -11) are critical for innate defences. Caspase-1 is activated by ligands of various canonical inflammasomes, and caspase-4, -5 and -11 … |
JIANJIN SHI et. al. |
| 2015 | 6 | Tumour Exosome Integrins Determine Organotropic Metastasis IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Ever since Stephen Paget’s 1889 hypothesis, metastatic organotropism has remained one of cancer’s greatest mysteries. Here we demonstrate that exosomes from mouse and human lung-, … |
AYUKO HOSHINO et. al. |
| 2015 | 7 | Fully Integrated Wearable Sensor Arrays For Multiplexed In Situ Perspiration Analysis IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Wearable sensor technologies are essential to the realization of personalized medicine through continuously monitoring an individual’s state of health. Sampling human sweat, which … |
WEI GAO et. al. |
| 2015 | 8 | The Contentious Nature Of Soil Organic Matter IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: The exchange of nutrients, energy and carbon between soil organic matter, the soil environment, aquatic systems and the atmosphere is important for agricultural productivity, … |
Johannes Lehmann; Markus Kleber; |
| 2015 | 9 | Caspase-11 Cleaves Gasdermin D for Non-canonical Inflammasome Signalling IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Intracellular lipopolysaccharide from Gram-negative bacteria including Escherichia coli, Salmonella typhimurium, Shigella flexneri, and Burkholderia thailandensis activates mouse … |
NOBUHIKO KAYAGAKI et. al. |
| 2015 | 10 | Paris Agreement Climate Proposals Need A Boost To Keep Warming Well Below 2 °C IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: The Paris climate agreement aims at holding global warming to well below 2 degrees Celsius and to pursue efforts to limit it to 1.5 degrees Celsius. To accomplish this, … |
JOERI ROGELJ et. al. |
| 2014 | 1 | Human-level Control Through Deep Reinforcement Learning IF:10 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: The theory of reinforcement learning provides a normative account, deeply rooted in psychological and neuroscientific perspectives on animal behaviour, of how agents may optimize … |
VOLODYMYR MNIH et. al. |
| 2014 | 2 | PD-1 Blockade Induces Responses By Inhibiting Adaptive Immune Resistance IF:10 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Therapies that target the programmed death-1 (PD-1) receptor have shown unprecedented rates of durable clinical responses in patients with various cancer types. One mechanism by … |
PAUL C TUMEH et. al. |
| 2014 | 3 | Integrative Analysis of 111 Reference Human Epigenomes IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: The reference human genome sequence set the stage for studies of genetic variation and its association with human disease, but epigenomic studies lack a similar reference. To … |
ANSHUL KUNDAJE et. al. |
| 2014 | 4 | Predictive Correlates Of Response To The Anti-PD-L1 Antibody MPDL3280A In Cancer Patients IF:10 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: The development of human cancer is a multistep process characterized by the accumulation of genetic and epigenetic alterations that drive or reflect tumour progression. These … |
ROY S HERBST et. al. |
| 2014 | 5 | The Contribution Of Outdoor Air Pollution Sources To Premature Mortality On A Global Scale IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Assessment of the global burden of disease is based on epidemiological cohort studies that connect premature mortality to a wide range of causes, including the long-term health … |
J Lelieveld; J S Evans; M Fnais; D Giannadaki; A Pozzer; |
| 2014 | 6 | Conductive Two-dimensional Titanium Carbide ‘clay’ with High Volumetric Capacitance IF:9 Related Papers Related Patents Related Grants Related Venues Related Experts View |
M. Ghidiu; M. Lukatskaya; Meng-qiang Zhao; Y. Gogotsi; M. Barsoum; |
| 2014 | 7 | Design, Fabrication And Control Of Soft Robots IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Conventionally, engineers have employed rigid materials to fabricate precise, predictable robotic systems, which are easily modelled as rigid members connected at discrete joints. … |
Daniela Rus; Michael T Tolley; |
| 2014 | 8 | High Secondary Aerosol Contribution to Particulate Pollution During Haze Events in China IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Rapid industrialization and urbanization in developing countries has led to an increase in air pollution, along a similar trajectory to that previously experienced by the … |
RU-JIN HUANG et. al. |
| 2014 | 9 | Global Effects Of Land Use On Local Terrestrial Biodiversity IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Human activities, especially conversion and degradation of habitats, are causing global biodiversity declines. How local ecological assemblages are responding is less clear–a … |
TIM NEWBOLD et. al. |
| 2014 | 10 | An Overview of N-heterocyclic Carbenes IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: The successful isolation and characterization of an N-heterocyclic carbene in 1991 opened up a new class of organic compounds for investigation. From these beginnings as academic … |
Matthew N Hopkinson; Christian Richter; Michael Schedler; Frank Glorius; |
| 2013 | 1 | Signatures of Mutational Processes in Human Cancer IF:10 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: All cancers are caused by somatic mutations; however, understanding of the biological processes generating these mutations is limited. The catalogue of somatic mutations from a … |
LUDMIL B ALEXANDROV et. al. |
| 2013 | 2 | Sequential Deposition As A Route to High-performance Perovskite-sensitized Solar Cells IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Following pioneering work, solution-processable organic-inorganic hybrid perovskites-such as CH3NH3PbX3 (X = Cl, Br, I)-have attracted attention as light-harvesting materials for … |
JULIAN BURSCHKA et. al. |
| 2013 | 3 | Diet Rapidly and Reproducibly Alters The Human Gut Microbiome IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Long-term dietary intake influences the structure and activity of the trillions of microorganisms residing in the human gut, but it remains unclear how rapidly and reproducibly … |
LAWRENCE A DAVID et. al. |
| 2013 | 4 | Van Der Waals Heterostructures IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Research on graphene and other two-dimensional atomic crystals is intense and is likely to remain one of the leading topics in condensed matter physics and materials science for … |
A K Geim; I V Grigorieva; |
| 2013 | 5 | Efficient Planar Heterojunction Perovskite Solar Cells By Vapour Deposition IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Many different photovoltaic technologies are being developed for large-scale solar energy conversion. The wafer-based first-generation photovoltaic devices have been followed by … |
Mingzhen Liu; Michael B Johnston; Henry J Snaith; |
| 2013 | 6 | Circular RNAs Are A Large Class of Animal RNAs with Regulatory Potency IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Circular RNAs (circRNAs) in animals are an enigmatic class of RNA with unknown function. To explore circRNAs systematically, we sequenced and computationally analysed human, mouse … |
SEBASTIAN MEMCZAK et. al. |
| 2013 | 7 | Ultra-sensitive Fluorescent Proteins for Imaging Neuronal Activity IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Fluorescent calcium sensors are widely used to image neural activity. Using structure-based mutagenesis and neuron-based screening, we developed a family of ultrasensitive protein … |
TSAI-WEN CHEN et. al. |
| 2013 | 8 | Commensal Microbe-derived Butyrate Induces The Differentiation of Colonic Regulatory T Cells IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Gut commensal microbes shape the mucosal immune system by regulating the differentiation and expansion of several types of T cell. Clostridia, a dominant class of commensal … |
YUKIHIRO FURUSAWA et. al. |
| 2013 | 9 | The Zebrafish Reference Genome Sequence and Its Relationship to The Human Genome IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Zebrafish have become a popular organism for the study of vertebrate gene function. The virtually transparent embryos of this species, and the ability to accelerate genetic … |
KERSTIN HOWE et. al. |
| 2013 | 10 | Ultralow Thermal Conductivity and High Thermoelectric Figure of Merit in SnSe Crystals IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: The thermoelectric effect enables direct and reversible conversion between thermal and electrical energy, and provides a viable route for power generation from waste heat. The … |
LI-DONG ZHAO et. al. |
| 2012 | 1 | Chromatin Patterns at Transcription Factor Binding Sites IF:8 Related Papers Related Patents Related Grants Related Venues Related Experts View |
Encode Chip-seq; T. F. Chip-seq; |
| 2012 | 2 | Opportunities and Challenges for A Sustainable Energy Future IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Access to clean, affordable and reliable energy has been a cornerstone of the world’s increasing prosperity and economic growth since the beginning of the industrial revolution. … |
Steven Chu; Arun Majumdar; |
| 2012 | 3 | A Roadmap for Graphene IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Recent years have witnessed many breakthroughs in research on graphene (the first two-dimensional atomic crystal) as well as a significant advance in the mass production of this … |
K S NOVOSELOV et. al. |
| 2012 | 4 | Comprehensive Molecular Portraits of Human Breast Tumors IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: We analysed primary breast cancers by genomic DNA copy number arrays, DNA methylation, exome sequencing, messenger RNA arrays, microRNA sequencing and reverse-phase protein … |
DANIEL C. KOBOLDT et. al. |
| 2012 | 5 | An Integrated Map of Genetic Variation from 1,092 Human Genomes IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: By characterizing the geographic and functional spectrum of human genetic variation, the 1000 Genomes Project aims to build a resource to help to understand the genetic … |
GONCALO R ABECASIS et. al. |
| 2012 | 6 | The Cancer Cell Line Encyclopedia Enables Predictive Modeling of Anticancer Drug Sensitivity IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: The systematic translation of cancer genomic data into knowledge of tumour biology and therapeutic possibilities remains challenging. Such efforts should be greatly aided by … |
JORDI BARRETINA et. al. |
| 2012 | 7 | Human Gut Microbiome Viewed Across Age and Geography IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Gut microbial communities represent one source of human genetic and metabolic diversity. To examine how gut microbiomes differ among human populations, here we characterize … |
TANYA YATSUNENKO et. al. |
| 2012 | 8 | Biodiversity Loss and Its Impact on Humanity IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: The most unique feature of Earth is the existence of life, and the most extraordinary feature of life is its diversity. Approximately 9 million types of plants, animals, protists … |
BRADLEY J CARDINALE et. al. |
| 2012 | 9 | Topological Domains in Mammalian Genomes Identified By Analysis of Chromatin Interactions IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: The spatial organization of the genome is intimately linked to its biological function, yet our understanding of higher order genomic structure is coarse, fragmented and … |
JESSE R DIXON et. al. |
| 2012 | 10 | Highly Efficient Organic Light-emitting Diodes from Delayed Fluorescence IF:10 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: The inherent flexibility afforded by molecular design has accelerated the development of a wide variety of organic semiconductors over the past two decades. In particular, great … |
Hiroki Uoyama; Kenichi Goushi; Katsuyuki Shizu; Hiroko Nomura; Chihaya Adachi; |
| 2011 | 1 | Solutions For A Cultivated Planet IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Increasing population and consumption are placing unprecedented demands on agriculture and natural resources. Today, approximately a billion people are chronically malnourished … |
JONATHAN A FOLEY et. al. |
| 2011 | 2 | Molecular Mechanisms And Clinical Applications Of Angiogenesis IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Blood vessels deliver oxygen and nutrients to every part of the body, but also nourish diseases such as cancer. Over the past decade, our understanding of the molecular mechanisms … |
Peter Carmeliet; Rakesh K Jain; |
| 2011 | 3 | Persistence Of Soil Organic Matter As An Ecosystem Property IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Globally, soil organic matter (SOM) contains more than three times as much carbon as either the atmosphere or terrestrial vegetation. Yet it remains largely unknown why some SOM … |
MICHAEL W I SCHMIDT et. al. |
| 2011 | 4 | Gut Flora Metabolism of Phosphatidylcholine Promotes Cardiovascular Disease IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Metabolomics studies hold promise for the discovery of pathways linked to disease processes. Cardiovascular disease (CVD) represents the leading cause of death and morbidity … |
ZENENG WANG et. al. |
| 2011 | 5 | Role Of YAP/TAZ In Mechanotransduction IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Cells perceive their microenvironment not only through soluble signals but also through physical and mechanical cues, such as extracellular matrix (ECM) stiffness or confined … |
SIRIO DUPONT et. al. |
| 2011 | 6 | Landscape of Transcription in Human Cells IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Eukaryotic cells make many types of primary and processed RNAs that are found either in specific subcellular compartments or throughout the cells. A complete catalogue of these … |
SARAH DJEBALI et. al. |
| 2011 | 7 | Enterotypes Of The Human Gut Microbiome IF:10 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Our knowledge of species and functional composition of the human gut microbiome is rapidly increasing, but it is still based on very few cohorts and little is known about … |
MANIMOZHIYAN ARUMUGAM et. al. |
| 2011 | 8 | Cancer Immunotherapy Comes of Age IF:10 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Activating the immune system for therapeutic benefit in cancer has long been a goal in immunology and oncology. After decades of disappointment, the tide has finally changed due … |
Ira Mellman; George Coukos; Glenn Dranoff; |
| 2011 | 9 | Progress And Challenges In Translating The Biology Of Atherosclerosis IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Atherosclerosis is a chronic disease of the arterial wall, and a leading cause of death and loss of productive life years worldwide. Research into the disease has led to many … |
Peter Libby; Paul M Ridker; Göran K Hansson; |
| 2011 | 10 | Bioinspired Self-repairing Slippery Surfaces With Pressure-stable Omniphobicity IF:10 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Creating a robust synthetic surface that repels various liquids would have broad technological implications for areas ranging from biomedical devices and fuel transport to … |
TAK-SING WONG et. al. |
| 2010 | 1 | A Human Gut Microbial Gene Catalogue Established By Metagenomic Sequencing IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: To understand the impact of gut microbes on human health and well-being it is crucial to assess their genetic potential. Here we describe the Illumina-based metagenomic … |
JUNJIE QIN et. al. |
| 2010 | 2 | A Map Of Human Genome Variation From Population-scale Sequencing IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: The 1000 Genomes Project aims to provide a deep characterization of human genome sequence variation as a foundation for investigating the relationship between genotype and … |
GONÇALO R ABECASIS et. al. |
| 2010 | 3 | The Next Generation Of Scenarios For Climate Change Research And Assessment IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Advances in the science and observation of climate change are providing a clearer understanding of the inherent variability of Earth’s climate system and its likely response to … |
RICHARD H MOSS et. al. |
| 2010 | 4 | Global Quantification Of Mammalian Gene Expression Control IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Gene expression is a multistep process that involves the transcription, translation and turnover of messenger RNAs and proteins. Although it is one of the most fundamental … |
BJÖRN SCHWANHÄUSSER et. al. |
| 2010 | 5 | Global Threats To Human Water Security And River Biodiversity IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Protecting the world’s freshwater resources requires diagnosing threats over a broad range of scales, from global to local. Here we present the first worldwide synthesis to … |
C J VÖRÖSMARTY et. al. |
| 2010 | 6 | Long Noncoding RNA HOTAIR Reprograms Chromatin State to Promote Cancer Metastasis IF:8 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Large intervening non-coding RNAs (lincRNAs) are pervasively transcribed in the genome yet their potential involvement in human disease is not well understood. Recent studies of … |
RAJNISH A. GUPTA et. al. |
| 2010 | 7 | Selective Inhibition Of BET Bromodomains IF:10 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Epigenetic proteins are intently pursued targets in ligand discovery. So far, successful efforts have been limited to chromatin modifying enzymes, or so-called epigenetic … |
PANAGIS FILIPPAKOPOULOS et. al. |
| 2010 | 8 | Genome Sequence of The Palaeopolyploid Soybean IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: Soybean (Glycine max) is one of the most important crop plants for seed protein and oil content, and for its capacity to fix atmospheric nitrogen through symbioses with soil-borne … |
JEREMY SCHMUTZ et. al. |
| 2010 | 9 | Mammalian MicroRNAs Predominantly Act To Decrease Target MRNA Levels IF:9 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: MicroRNAs (miRNAs) are endogenous approximately 22-nucleotide RNAs that mediate important gene-regulatory events by pairing to the mRNAs of protein-coding genes to direct their … |
Huili Guo; Nicholas T Ingolia; Jonathan S Weissman; David P Bartel; |
| 2010 | 10 | The Landscape of Somatic Copy-number Alteration Across Human Cancers IF:10 Summary Related Papers Related Patents Related Grants Related Venues Related Experts View Abstract: A powerful way to discover key genes with causal roles in oncogenesis is to identify genomic regions that undergo frequent alteration in human cancers. Here we present … |
RAMEEN BEROUKHIM et. al. |