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Paper Digest: Recent Papers on Ebola Virus Disease

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To help researchers quickly catch up the most recent work in health science, Paper Digest Team extracted all recent Ebola Virus Disease related papers on our radar, and list them in this article. This article will be updated on a daily basis to reflect new progresses in this area. (Last updated on: 2022-06-30) Based in New York, Paper Digest is dedicated to producing high-quality text analysis results that people can acturally use on a daily basis. Since 2018, we have been serving users across the world with a number of exclusive services on ranking, search, tracking and automatic literature review.

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New York City, New York, 10017
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TABLE 1: Paper Digest: Recent Papers on Ebola Virus Disease

Paper Author(s) Source Date
1 Ebola, Informal Settlements and The Role of Place in Infectious Disease Vulnerability: Evidence from The 2014-2016 Ebola Outbreak in Urban Sierra Leone
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Highlight: In this paper, we consider how vulnerability is also associated with the characteristics of place, especially the social setting of the informal settlement.		 S HARRIS ALI et. al. Disasters 2022-06-28
2 Rumor Spread and Control During The West African Ebola Epidemic in Liberia
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Abstract: The severity of the 2014-2015 West African Ebola epidemic in Liberia was coupled with widespread misunderstanding about Ebola among Liberian citizens and the proliferation of …		 MONIQUE MITCHELL TURNER et. al. Disasters 2022-06-28
3 Recombinant Vesicular Stomatitis Vaccine Against Nipah Virus Has A Favorable Safety Profile: Model for Assessment of Live Vaccines with Neurotropic Potential
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Highlight: With funding from the Coalition of Epidemic Preparedness Innovations (CEPI), we are developing a chimeric vaccine (PHV02) composed of recombinant vesicular stomatitis virus (VSV) expressing the envelope glycoproteins of both Ebola virus (EBOV) and NiV.		 THOMAS P MONATH et. al. PLoS pathogens 2022-06-27
4 Strengthening Vaccines and Medicines Manufacturing Capabilities in Africa: Challenges and Perspectives
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Abstract: Africa carries a high burden of infectious diseases. Every year, millions of Africans contract tuberculosis, malaria, and many other diseases. Malaria kills hundreds of thousands …		 AbdulRahman A Saied; Asmaa A Metwally; Manish Dhawan; Om Prakash Choudhary; Hani Aiash; EMBO molecular medicine 2022-06-27
5 Geospatial Clustering and Correlates of Deaths During The Ebola Outbreak in Liberia: A Bayesian Geoadditive Semiparametric Analysis of Nationally Representative Cross-sectional Survey Data
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Highlight: The analysis covered 11 928 (women=7854 and men=4074) respondents for whom complete data were available.		 Fiifi Amoako Johnson; Barbara Sakyi; BMJ open 2022-06-27
6 A Sequential Test for Assessing The Effectiveness of Response Strategies During An Emerging Epidemic
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Highlight: A statistical test is developed in this paper to detect changes in fatality rate over time during the course of an emerging infectious disease.		 K F Lam; Yuanke Qu; Biometrical journal. Biometrische Zeitschrift 2022-06-26
7 Comparative Value-based Pricing of An Ebola Vaccine in Resource-constrained Countries Based on Cost-effectiveness Analysis
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Highlight: Using Ebola virus disease (EVD) as exemplar, we aim to elucidate the estimation of a jurisdiction-specific value-based price (VBP) for a vaccine package and to consider how prices compare across selected countries that have experienced EVD outbreaks.		 M Obeng-Kusi; B Erstad; D J Roe; I Abraham; Journal of medical economics 2022-06-24
8 Zaire Ebolavirus Surveillance Near The Bikoro Region of The Democratic Republic of The Congo During The 2018 Outbreak Reveals Presence of Seropositive Bats
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Highlight: We collected serum from 144 bats in the Cuvette department with 6.9% seropositivity against the EBOV glycoprotein and 14.3% seropositivity for serum collected from 27 fruit bats and one Molossinae in the Likouala department.		 STEPHANIE N SEIFERT et. al. PLoS neglected tropical diseases 2022-06-22
9 Safety, Reactogenicity, and Immunogenicity of A 2-dose Ebola Vaccine Regimen of Ad26.ZEBOV Followed By MVA-BN-Filo in Healthy Adult Pregnant Women: Study Protocol for A Phase 3 Open-label Randomized Controlled Trial
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Abstract: Risks to mother and fetus following Ebola virus infection are very high. Evaluation of safety and immunogenicity of non-replicating Ebola vaccine candidates is a priority for use …		 ETIENNE KARITA et. al. Trials 2022-06-20
10 Antibodies to Combat Viral Infections: Development Strategies and Progress
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Highlight: Here, we describe advances in antibody discovery and engineering that have led to the development of mAbs for use against infections caused by viruses including SARS-CoV-2, respiratory syncytial virus (RSV), Ebola virus (EBOV), human cytomegalovirus (HCMV) and influenza.		 Giuseppe Pantaleo; Bruno Correia; Craig Fenwick; Victor S Joo; Laurent Perez; Nature reviews. Drug discovery 2022-06-20
11 Repurposing Molnupiravir for COVID-19: The Mechanisms of Antiviral Activity
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Highlight: To date, the data collectively suggest that Molnupiravir possesses promising antiviral activity as well as favorable prophylactic efficacy, attributed to its effective mutagenic property of disrupting viral replication. This review discusses the mechanisms of action of Molnupiravir and highlights its clinical utility by disabling SARS-CoV-2 replication, thereby ameliorating COVID-19 severity.		 Ashley Jia Wen Yip; Zheng Yao Low; Vincent T K Chow; Sunil K Lal; Viruses 2022-06-20
12 Circulating Tissue Factor-positive Extracellular Vesicles and Their Association with Thrombosis in Different Diseases
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Highlight: In this review, we will summarize the association between TF + EVs and activation of coagulation and survival in different types of diseases, including cancer, sepsis, and infections with different viruses, such as human immunodeficiency virus (HIV), influenza A virus (IAV), and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).		 Yohei Hisada; Ana Teresa Azevedo Sachetto; Nigel Mackman; Immunological reviews 2022-06-16
13 Natural History of Sudan Ebolavirus to Support Medical Countermeasure Development
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Highlight: In this study, twelve cynomolgus macaques ( ) were challenged intramuscularly with 1000 PFUs of SUDV and were followed under continuous telemetric surveillance.		 CAROLINE CARBONNELLE et. al. Vaccines 2022-06-16
14 Comparative Overview of Emerging RNA Viruses: Epidemiology, Pathogenesis, Diagnosis and Current Treatment
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Abstract: From many decades, emerging infections have threatened humanity. The pandemics caused by different CoVs have already claimed and will continue to claim millions of lives. The …		 ISHANI CHAKRABARTTY et. al. Annals of medicine and surgery (2012) 2022-06-11
15 Health System Resilience During COVID-19 Understanding SRH Service Adaptation in North Kivu
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Highlight: This study draws on quantitative analysis of routine data from four health zones, a document review of policies and protocols, and 13 key-informant interviews with staff from the Ministry of Public Health, United Nations agencies, international and national non-governmental organizations, and civil society organizations.		 Lara S Ho; Maria Paola Bertone; Wesam Mansour; Cyprien Masaka; Jessica Kakesa; Reproductive health 2022-06-06
16 Regulating Clinical Trials in A Resource-limited Setting During The Ebola Public Health Emergency in Sierra Leone
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Highlight: Regulating clinical trials during the Ebola outbreak in Sierra Leone required expedited evaluation to identify medical products that could be promptly introduced to combat the epidemic in the absence of approved treatment or prevention. This article explored the decisions taken by the Pharmacy Board of Sierra Leone through its Expert Committee on Medicine Safety and Clinical Trials regarding clinical trials oversight during the Ebola epidemic and the lessons learned.		 ONOME T ABIRI et. al. Trials 2022-06-06
17 Exo-SIR: An Epidemiological Model to Analyze The Impact of Exogenous Spread of Infection
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Highlight: In this paper, we introduce the Exo-SIR model, an extension of the popular SIR model and a few variants of the model.		 Nirmal Kumar Sivaraman; Manas Gaur; Shivansh Baijal; Sakthi Balan Muthiah; Amit Sheth; International journal of data science and analytics 2022-06-06
18 Ebola Virus Outbreak Returns to The Democratic Republic of Congo: An Urgent Rising Concern
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Abstract: On April 23, 2022, the Ministry of Health of the Democratic Republic of the Congo announced an EVD outbreak after discovering 2 confirmed cases and identifying 267 contacts. With …		 JEFFREY SUN et. al. Annals of medicine and surgery (2012) 2022-06-06
19 Ophthalmic Sequelae and Psychosocial Impact in Pediatric Ebola Survivors
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Abstract: Ebola virus disease (EVD) outbreaks in West Africa (2013-2016) and the Democratic Republic of Congo (2018-2020) have resulted in thousands of EVD survivors who remain at-risk for …		 JESSICA G SHANTHA et. al. EClinicalMedicine 2022-06-03
20 New Analogues of Uridine As Possible Anti-Viral Agents Specific to SARS-CoV-2
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Highlight: The aim of our work was the creation of new 5-substituted uridine derivatives as potential inhibitors of coronavirus RNA-dependent RNA polymerase.		 A A MASLOVA et. al. Molecular biology 2022-06-03
21 Contact Tracing: Barriers and Facilitators
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Abstract: Contact tracing-the process of identifying, isolating, and managing infected persons and their contacts-is a recognized public health measure for controlling the transmission of …		 Wafaa M El-Sadr; Joey Platt; Melanie Bernitz; Melissa Reyes; American journal of public health 2022-06-02
22 Correction: Implementing A DHIS2 Ebola Virus Disease Module During The 2021 Guinea Ebola Outbreak
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 BMJ global health 2022-06-02
23 Polypyridyl Ruthenium Complexes As Bifunctional TAR RNA Binders and HIV-1 Reverse Transcriptase Inhibitors
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Abstract: Inhibitors of type 1 human immunodeficiency virus (HIV-1) reverse transcriptase are central to anti-HIV therapy. Most of their targets are enzymes, while very few could bind to …		 MENG-FAN WANG et. al. Journal of inorganic biochemistry 2022-06-02
24 Transchromosomic Bovines-derived Broadly Neutralizing Antibodies As Potent Biotherapeutics to Counter Important Emerging Viral Pathogens with A Special Focus on SARS-CoV-2, MERS-CoV, Ebola, Zika, HIV-1, and Influenza A Virus
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Highlight: This article highlights recent developments in the field of bovine-derived biotherapeutics, which are seen as a practical platform for developing safe and effective antivirals with broad activity, particularly considering emerging viral infections such as SARS-CoV-2, Ebola, Middle East respiratory syndrome coronavirus, Zika, human immunodeficiency virus type 1, and influenza A virus.		 ABDULRAHMAN A SAIED et. al. Journal of medical virology 2022-06-02
25 Why Does Viral RNA Sometimes Persist After Recovery from Acute Infections?
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Abstract: DNA viruses often persist in the body of their host, becoming latent and recurring many months or years later. By contrast, most RNA viruses cause acute infections that are …		 Diane E Griffin; PLoS biology 2022-06-01
26 A Systematic Review to Describe Patterns of Animal and Human Viral Research in Rwanda
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Highlight: This review describes the status of human and animal virus research in Rwanda and identifies relevant research and operational gaps.		 M Fausta Dutuze; Maurice Byukusenge; Anselme Shyaka; Rebecca C Christofferson; International health 2022-06-01
27 Detecting Sentiment Toward Emerging Infectious Diseases on Social Media: A Validity Evaluation of Dictionary-Based Sentiment Analysis
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Abstract: Despite the popularity and efficiency of dictionary-based sentiment analysis (DSA) for public health research, limited empirical evidence has been produced about the validity of …		 Sanguk Lee; Siyuan Ma; Jingbo Meng; Jie Zhuang; Tai-Quan Peng; International journal of environmental research and public … 2022-06-01
28 Toward Health System Recovery in The Aftermath of Ebola Outbreak in Guinea: New Approaches for Improved Knowledge of Target Populations at The Community Level
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Abstract: Before the COVID-19 pandemic, Guinea has been the epicenter of the huge West Africa Ebola outbreak (2014-2016), that impact heavily the health system. Demographic information is …		 MANDY KADER KONDE et. al. Journal of primary care & community health 2022-05-31
29 NK Cell Subset Redistribution and Antibody Dependent Activation After Ebola Vaccination in Africans
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Abstract: Natural killer cells play an important role in the control of viral infections both by regulating acquired immune responses and as potent innate or antibody-mediated cytotoxic …		 HELEN R WAGSTAFFE et. al. Vaccines 2022-05-31
30 Asymptomatic Malaria Infection and The Immune Response to The 2-Dose Ad26.ZEBOV, MVA-BN-Filo Ebola Vaccine Regimen in Adults and Children
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Highlight: As Ebola virus (EBOV) outbreaks have occurred mainly in malaria-endemic countries, we have assessed whether asymptomatic malaria affects immune responses to the 2-dose Ad26.ZEBOV, MVA-BN-Filo Ebola vaccine regimen.		 D Ishola; D; Clinical infectious diseases : an official publication of … 2022-05-30
31 Interactions Among Cross-Border Contiguous Communities and Implications for Managing Pandemics – The Case of Ghana and Burkina Faso During The Ebola Outbreak in West Africa: A Qualitative Study
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Abstract: In sub-Saharan Africa, extensive migratory activities and interactions exist especially amongst unmanned cross-border communities between countries sharing common borders which …		 Dennis Chirawurah; Niagia Santuah; Stephen Apanga; Annals of global health 2022-05-30
32 Infectious Disease Equity Market Volatility, Geopolitical Risk, Speculation, and Commodity Returns: Comparative Analysis of Five Epidemic Outbreaks
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Highlight: This paper uses a time-varying Granger causality test and time-varying parameter vector autoregression with stochastic volatility model to analyze the effects of infectious disease equity market volatility (ID-EMV), geopolitical risk (GPR), and speculation on commodity returns.		 Shaobo Long; Jiaqi Guo; Research in international business and finance 2022-05-30
33 Homage to Ebola Fighters: Black Labor and Humanitarian Media Campaigns
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Abstract: During the Ebola outbreak that hit Guinea in 2014, most of the people employed at the Wonkifong Ebola treatment unit were from Africa or Cuba. Despite the recruitment of black …		 Veronica Gomez-Temesio; Medical anthropology quarterly 2022-05-30
34 Emerging Viruses: Cross-species Transmission of Coronaviruses, Filoviruses, Henipaviruses, and Rotaviruses from Bats
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Abstract: Emerging infectious diseases, especially if caused by bat-borne viruses, significantly affect public health and the global economy. There is an urgent need to understand the …		 JIN TIAN et. al. Cell reports 2022-05-30
35 Modelling The Potential Influence of Human Migration and Strain Mutation on Ebola Virus Disease Dynamics
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Highlight: In this paper, we formulate a mathematical model of Ebola virus disease dynamics, that describes the introduction of a new strain of ebolavirus, through either mutation or immigration (which can be continuous or impulsive) of infectives.		 S. D. D. Njankou; F. Nyabadza; med.infectious-diseases 2022-05-30
36 Risk Factors for Ebola Virus Persistence in Semen of Survivors – Liberia
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Highlight: This study was designed to understand how the acute course of EVD, convalescence, and host immune and genetic factors may play a role in prolonged viral persistence in semen.		 JONATHAN DYAL et. al. Clinical infectious diseases : an official publication of … 2022-05-27
37 A Highly Attenuated Vesiculovax Vaccine Rapidly Protects Nonhuman Primates Against Lethal Marburg Virus Challenge
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Abstract: Marburg virus (MARV), an Ebola-like virus, remains an eminent threat to public health as demonstrated by its high associated mortality rate (23-90%) and recent emergence in West …		 COURTNEY WOOLSEY et. al. PLoS neglected tropical diseases 2022-05-27
38 Mental Distress Before and During The COVID-19 Pandemic: A Longitudinal Study Among Communities Affected By Ebola Virus Disease in The DR Congo
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Abstract: Associated with high mortality rate, fear, and anxiety, Ebola Virus Disease (EVD) is a significant risk factor for mental distress. This longitudinal study aims to investigate the …		 JUDE MARY CÉNAT et. al. Psychiatry research 2022-05-27
39 Adipocytes Are Susceptible to Ebola Virus Infection
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Abstract: Adipose tissue is an endocrine organ with strong proinflammatory capacity; however, the role of this tissue in highly pathogenic virus infections has not been extensively …		 FRANCOISE A GOURRONC et. al. Virology 2022-05-27
40 Lessons Learned from The World Health Organization’s Late Initial Response to The 2014-2016 Ebola Outbreak in West Africa
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Abstract: The purpose of this article is to 1) examine the role of the World Health Organization (WHO) in controlling infectious disease outbreaks, 2) evaluate if the WHO’s initial response …		 Chulwoo Park; Journal of public health in Africa 2022-05-26
41 The Burden of Unrecognized Ebola Virus Infection
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 Karen O’Leary; Nature medicine 2022-05-26
42 Flattening The Curve: Voluntary Association Participation and The 2013-2016 West Africa Ebola Epidemic
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Highlight: To what extent does voluntary association participation correlate with reduced Ebola duration in districts across Guinea, Liberia, and Sierra Leone during the 2013-2016 West Africa Ebola epidemic? In this first cross-national quantitative study of Ebola outcomes across the three countries with nearly all the Ebola cases globally, I investigate how social capital influences epidemic outcomes.		 Michelle Reddy; Disasters 2022-05-25
43 Resilience Among Health Care Workers While Working During A Pandemic: A Systematic Review and Meta Synthesis of Qualitative Studies
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Abstract: The COVID-19 pandemic has reinforced the need to attend to Health Care Workers (HCWs) mental health. What promotes resilience in HCWs during pandemics is largely unknown. To …		 Mariah Curtin; Helen L Richards; Donal G Fortune; Clinical psychology review 2022-05-24
44 Risk Prediction Score for Pediatric Patients with Suspected Ebola Virus Disease
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Abstract: Rapid diagnostic tools for children with Ebola virus disease (EVD) are needed to expedite isolation and treatment. To evaluate a predictive diagnostic tool, we examined …		 ALICIA E GENISCA et. al. Emerging infectious diseases 2022-05-24
45 Effect of Recombinant Vesicular Stomatitis Virus-Zaire Ebola Virus Vaccination on Ebola Virus Disease Illness and Death, Democratic Republic of The Congo
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Abstract: We conducted a retrospective cohort study to assess the effect vaccination with the live-attenuated recombinant vesicular stomatitis virus-Zaire Ebola virus vaccine had on deaths …		 NEIL RUPANI et. al. Emerging infectious diseases 2022-05-24
46 Pyronaridine Protects Against SARS-CoV-2 Infection in Mouse
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Abstract: There are currently relatively few small-molecule antiviral drugs that are either approved or emergency-approved for use against severe acute respiratory coronavirus 2 …		 ANA C PUHL et. al. ACS infectious diseases 2022-05-24
47 A Novel Property of Hexokinase Inhibition By Favipiravir and Proposed Advantages Over Molnupiravir and 2 Deoxy D Glucose in Treating COVID-19
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Abstract: In the wake of SARS-CoV-2’s global spread, human activities from health to social life to education have been affected. Favipiravir and Molnupiravir exhibited novel hexokinase …		 Prajakta Kulkarni; Sriram Padmanabhan; Biotechnology letters 2022-05-24
48 Measuring Feelings About Choices and Risks: The Berlin Emotional Responses to Risk Instrument (BERRI)
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Highlight: We introduce a brief instrument specifically validated for measuring positive and negative feelings about risks-the Berlin Emotional Responses to Risk Instrument (BERRI).		 DAFINA PETROVA et. al. Risk analysis : an official publication of the Society for … 2022-05-23
49 Evaluation of Viral Load in Patients with Ebola Virus Disease in Liberia: A Retrospective Observational Study
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Highlight: Here, our aim was to conduct a laboratory-based re-evaluation of the viral loads of a large cohort of Liberian patients with Ebola virus disease and analyse these data in the broader context of the west Africa epidemic. In this retrospective observational study, whole blood samples from patients at the Eternal Love Winning Africa Ebola treatment unit (Monrovia, Liberia) were re-extracted with an optimised protocol and analysed by droplet digital PCR (ddPCR) using a novel semi-strand specific assay to measure viral load.		 M JEREMIAH MATSON et. al. The Lancet. Microbe 2022-05-23
50 Measuring The Unknown: An Estimator and Simulation Study for Assessing Case Reporting During Epidemics
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Abstract: The fraction of cases reported, known as ‘reporting’, is a key performance indicator in an outbreak response, and an essential factor to consider when modelling epidemics and …		 CHRISTOPHER I JARVIS et. al. PLoS computational biology 2022-05-23
51 The Post-colonialist Condition, Suspicion, and Social Resistance During The West African Ebola Epidemic: The Importance of Frantz Fanon for Global Health
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Abstract: The scholarship of Frantz Fanon has been recognized across numerous disciplines as a unique and necessary intervention for critical analyses of the (post)colonial condition. Yet, …		 S Harris Ali; Jarrett Robert Rose; Social science & medicine (1982) 2022-05-23
52 Isoform-specific O-glycosylation Dictates Ebola Virus Infectivity
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Highlight: This work represents a comprehensive site-specific analysis of EBOV GP, with 47 O-glycosites identified, and sheds light on differential regulation of EBOV GP glycosylation initiated by host GalNAc-Ts.		 I. BAGDONAITE et. al. bio.microbiology 2022-05-20
53 Structural Insights Into The Interactions Between Lloviu Virus VP30 and Nucleoprotein
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Abstract: The family Filoviridae comprises many notorious viruses, such as Ebola virus (EBOV) and Marburg virus (MARV), that can infect humans and nonhuman primates. Lloviu virus (LLOV), a …		 WEIYAN SUN et. al. Biochemical and biophysical research communications 2022-05-20
54 Beyond Lassa Fever: Systemic and Structural Barriers to Disease Detection and Response in Sierra Leone
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Abstract: Lassa fever (LF) often presents clinically as undifferentiated febrile illness. Lassa Fever cases in Sierra Leone have been falling since the 2014-2016 Ebola epidemic. Data from …		 Hana Rohan; PLoS neglected tropical diseases 2022-05-19
55 Rapid and Sensitive Detection of Ebola RNA in An Unamplified Sample Based on CRISPR-Cas13a and DNA Roller Machine
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Abstract: A fast and simple Cas13a-based assay approach for direct detecting Ebola RNA in unamplified samples is reported. The procedure (named Cas-Roller) is comprised of a 10-min …		 XIAO-MIN HANG et. al. Biosensors & bioelectronics 2022-05-18
56 The Evolution of The National Special Pathogen System of Care
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Abstract: Infectious disease outbreaks and pandemics have repeatedly threatened public health and have severely strained healthcare delivery systems throughout the past century. Pathogens …		 VIKRAMJIT MUKHERJEE et. al. Health security 2022-05-18
57 Correction: Zoonotic Risk Factors Associated with Seroprevalence of Ebola Virus GP Antibodies in The Absence of Diagnosed Ebola Virus Disease in The Democratic Republic of Congo
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Abstract: [This corrects the article DOI: 10.1371/journal.pntd.0009566.]. …		 ANNA BRATCHER et. al. PLoS neglected tropical diseases 2022-05-18
58 Special Pathogens Readiness in The United States: From Ebola to COVID-19 to Disease X and Beyond
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 Lauren M Sauer; Vikramjit Mukherjee; Health security 2022-05-18
59 Gold, Bonds, and Epidemics: A Safe Haven Study
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Highlight: We study the effectiveness as safe haven during the epidemics caused by SARS, Ebola, Zika, Swine Flu, and COVID-19. To this end, this study employs a DCC-GARCH model to analyze the conditional correlations between daily returns of S&P 500 and MSCI Emerging Markets Index with gold and the major sovereign bonds.		 Tonmoy Choudhury; Harald Kinateder; Biwesh Neupane; Finance research letters 2022-05-16
60 Clinical Sequelae Among Individuals with Pauci-symptomatic or Asymptomatic Ebola Virus Infection and Unrecognised Ebola Virus Disease in Liberia: A Longitudinal Cohort Study
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Highlight: Between June 17, 2015, and June 30, 2017, we studied a cohort of Ebola virus disease survivors and their contacts in Liberia.		 J DANIEL KELLY et. al. The Lancet. Infectious diseases 2022-05-16
61 Host Regulation of Ebola Virus Egress and Spread: Role of Cytoskeletal Filamin Proteins
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Highlight: We have shown that eVP40 hijacks or recruits select host proteins to facilitate the budding process.		 Ariel Shepley-McTaggart; Olena Shtanko; Ron N Harty; FASEB journal : official publication of the Federation of … 2022-05-13
62 The Effects of Point Mutations on The Dimerization Domain of Ebola Virus Protein VP40
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Highlight: The eVP40 dimerization and filament formation is necessary for viral budding from the host cell membrane. This project aims to investigate which amino acid residues in this N-terminal dimerization domain are necessary for the protein to be able to oligomerize at the plasma membrane inner leaflet.		 Jacob Conarty; Himani Patel; Olaf Wiest; Souad Amiar; Robert Stahelin; FASEB journal : official publication of the Federation of … 2022-05-13
63 Modelling The Role of Human Behaviour in Ebola Virus Disease (EVD) Transmission Dynamics
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Highlight: To study the role that human behaviour plays in Ebola disease dynamics, in this paper, we design an Ebola virus disease model with disease transmission dynamics based on a new exponential nonlinear incidence function.		 Sylvie Diane Djiomba Njankou; Farai Nyabadza; Computational and mathematical methods in medicine 2022-05-13
64 Mental Health and Well-Being Needs Among Non-Health Essential Workers During Recent Epidemics and Pandemics
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Abstract: Essential workers, those who work in a variety of sectors that are critical to sustain the societal infrastructure, were affected both physically and mentally by the COVID-19 …		 NASHIT CHOWDHURY et. al. International journal of environmental research and public … 2022-05-13
65 Application and Comparison of Lyophilisation Protocols to Enhance Stable Long-term Storage of Filovirus Pseudotypes for Use in Antibody Neutralisation Tests
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Highlight: In this study we assessed stability and functionality after long-term storage of lyophilised filovirus pseudotypes for use in neutralisation assays.		 M. MAYORA NETO et. al. bio.microbiology 2022-05-13
66 Assessment of Life Cycle Modeling Systems As Prediction Tools for A Possible Attenuation of Recombinant Ebola Viruses
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Abstract: Ebola virus (EBOV) causes hemorrhagic fever in humans with high case fatality rates. In the past, a number of recombinant EBOVs expressing different reporters from additional …		 Bianca S Bodmer; Thomas Hoenen; Viruses 2022-05-13
67 Assessment of Infection Prevention and Control Measures at Points of Entry in Sierra Leone in 2021: A Cross-Sectional Study
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Abstract: Implementing and monitoring infection prevention and control (IPC) measures at immigration points of entry (PoEs) is key to preventing infections, reducing excessive use of …		 KADIJATU NABIE KAMARA et. al. International journal of environmental research and public … 2022-05-13
68 3,4- Seco -Isopimarane Diterpenes from The Twigs and Leaves of Isodon Flavidus
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Abstract: Three isopimarane diterpenes [fladins B ( ), C ( ), and D ( )] were isolated from the twigs and leaves of Chinese folk medicine, . The chemical structures were determined by the …		 WAN-FEI LI et. al. Molecules (Basel, Switzerland) 2022-05-12
69 Mechanisms of Phosphatidylserine Influence on Viral Production: A Computational Model of Ebola Virus Matrix Protein Assembly
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Abstract: Ebola virus (EBOV) infections continue to pose a global public health threat, with high mortality rates and sporadic outbreaks in Central and Western Africa. A quantitative …		 XIAO LIU et. al. The Journal of biological chemistry 2022-05-11
70 Designing A Novel Multi‑epitope Vaccine Against Ebola Virus Using Reverse Vaccinology Approach
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Abstract: Ebola virus (EBOV) is a dangerous zoonotic infectious disease. To date, more than 25 EBOV outbreaks have been documented, the majority of which have occurred in Central Africa. …		 MORTEZA ALIZADEH et. al. Scientific reports 2022-05-11
71 Drug-like Inhibitors of DC-SIGN Based on A Quinolone Scaffold
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Abstract: DC-SIGN (dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin) is a pattern recognition receptor expressed on immune cells and involved in the …		 HENGXI ZHANG et. al. ACS medicinal chemistry letters 2022-05-10
72 Effective Interventions to Ensure MCH (Maternal and Child Health) Services During Pandemic Related Health Emergencies (Zika, Ebola, and COVID-19): A Systematic Review
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Abstract: Ensuring accessible and quality health care for women and children is an existing challenge, which is further exacerbated during pandemics. There is a knowledge gap about the …		 SUBRATA KUMAR PALO et. al. PloS one 2022-05-10
73 Sagacious Perceptive on Marburg Virus Foregrounding The Recent Findings :A Critical Review
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Highlight: This review emphasis on the novel current facts determined through various studies related to Marburg virus infection. From these promising theories, review tries to put forward the importance of various study conclusions which are likely to provide major impact on health sector in near future.		 Bilha Baby; Rajalakshmi R; Manju M Nair; Roshni P R; Infectious disorders drug targets 2022-05-10
74 Major Bat-borne Zoonotic Viral Epidemics in Asia and Africa: A Systematic Review and Meta-analysis
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Highlight: Therefore, these bat-associated epidemics provide a significant number of hints, including respiratory cellular tropism, more intense susceptibility to these cell types, and overall likely to become a pandemic for the next spillover. In this systematic review, we analysed data to insight, through bat-originated spillover in Asia and Africa.		 SHAHNEAZ ALI KHAN et. al. Veterinary medicine and science 2022-05-10
75 Ubiquitination of Ebola Virus VP35 at Lysine 309 Regulates Viral Transcription and Assembly
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Abstract: Ebola virus (EBOV) VP35 is a polyfunctional protein involved in viral genome packaging, viral polymerase function, and host immune antagonism. The mechanisms regulating VP35’s …		 SARAH VAN TOL et. al. PLoS pathogens 2022-05-09
76 Setting-up An Ebola Vaccine Trial in A Remote Area of The Democratic Republic of The Congo: Challenges, Mitigations, and Lessons Learned
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Abstract: Since the largest Ebola outbreak in West Africa (2013-2016) highlighted the potential threat of the Ebola virus to the world, several vaccines have been under development by …		 TRÉSOR ZOLA MATUVANGA et. al. Vaccine 2022-05-09
77 TRIM25 and ZAP Target The Ebola Virus Ribonucleoprotein Complex to Mediate Interferon-induced Restriction
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Abstract: Ebola virus (EBOV) causes highly pathogenic disease in primates. Through screening a library of human interferon-stimulated genes (ISGs), we identified TRIM25 as a potent …		 RUI PEDRO GALÃO et. al. PLoS pathogens 2022-05-09
78 Ebola Outbreak in DR Congo
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 Munyaradzi Makoni; Lancet (London, England) 2022-05-08
79 Ebola Virus Encodes Two MicroRNAs in Huh7-Infected Cells
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Highlight: From the miRDB database, miR-MAY-251 and miR-MAK-403 displayed on average more than 700 potential human host target candidates, 25% of which had a confidence score higher than 80%. By RT-qPCR and dual luciferase assays, we assessed the potential regulatory effect of these two EBOV miRNAs on selected host mRNA targets.		 IDRISSA DIALLO et. al. International journal of molecular sciences 2022-05-07
80 Development and Scalable Production of Newcastle Disease Virus-Vectored Vaccines for Human and Veterinary Use
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Abstract: The COVID-19 pandemic has highlighted the need for efficient vaccine platforms that can rapidly be developed and manufactured on a large scale to immunize the population against …		 Julia P C Fulber; Amine A Kamen; Viruses 2022-05-06
81 Severe Anxiety and PTSD Symptoms Among Ebola Virus Disease Survivors and Healthcare Workers in The Context of The COVID-19 Pandemic in Eastern DR Congo
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Abstract: Ebola virus disease (EVD) survivors and healthcare workers (HCWs) face stress, fear, and stigma during the COVID-19 pandemic that can induce severe symptoms of anxiety and …		 Jude Mary Cénat; Cécile Rousseau; Jacqueline Bukaka; Rose Darly Dalexis; Mireille Guerrier; Frontiers in psychiatry 2022-05-06
82 The Impact of The Ebola Epidemics on Children’s Rights: A Scoping Review
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Highlight: A scoping review from PubMed, Medline, Cochrane Library and Web of Science was performed using PRISMA-ScR guidelines.		 IRENE LUNGHI et. al. Global health action 2022-05-04
83 Program Planning to Develop Infrastructure for Cancer Care in Liberia
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Abstract: Liberia’s health infrastructure was completely devastated after 14 years of back-to-back civil war. Postconflict rebuilding of the country’s health workforce and infrastructure …		 Ann Marie Beddoe; Wilhelmina Jallah; Bernice Dahn; JCO global oncology 2022-05-04
84 Pandemic, Epidemic, Endemic: B Cell Repertoire Analysis Reveals Unique Anti-Viral Responses to SARS-CoV-2, Ebola and Respiratory Syncytial Virus
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Abstract: Immunoglobulin gene heterogeneity reflects the diversity and focus of the humoral immune response towards different infections, enabling inference of B cell development processes. …		 ALEXANDER STEWART et. al. Frontiers in immunology 2022-05-03
85 Topological and Multivalent Effects in Glycofullerene Oligomers As EBOLA Virus Inhibitors
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Abstract: The synthesis of new biocompatible antiviral materials to fight against the development of multidrug resistance is being widely explored. Due to their unique globular structure …		 JAVIER RAMOS-SORIANO et. al. International journal of molecular sciences 2022-05-03
86 Has Ebola Delayed Progress on Access to Routine Care and Financial Protection in Sierra Leone? Evidence from A Difference-in-differences Analysis with Propensity Score Weighting
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Abstract: Covid-19 has highlighted the need to understand the long-term impact of epidemics on health systems. There is extensive evidence that the Ebola epidemic of 2014-16 dramatically …		 Jessica King; Zia Sadique; Michael Amara; Josephine Borghi; Social science & medicine (1982) 2022-04-30
87 Glycopeptide Antibiotic Teicoplanin Inhibits Cell Entry of SARS-CoV-2 By Suppressing The Proteolytic Activity of Cathepsin L
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Abstract: Since the outbreak of the coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), public health worldwide has been greatly …		 FEI YU et. al. Frontiers in microbiology 2022-04-28
88 Automated Laser-Transfer Synthesis of High-Density Microarrays for Infectious Disease Screening
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Abstract: Laser-induced forward transfer (LIFT) is a rapid laser-patterning technique for high-throughput combinatorial synthesis directly on glass slides. A lack of automation and …		 GRIGORI PARIS et. al. Advanced materials (Deerfield Beach, Fla.) 2022-04-28
89 Development of Azaindole-Based Frameworks As Potential Antiviral Agents and Their Future Perspectives
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Abstract: The azaindole (AI) framework continues to play a significant role in the design of new antiviral agents. Modulating the position and isosteric replacement of the nitrogen atom of …		 Urvashi; J B Senthil Kumar; Parthasarathi Das; Vibha Tandon; Journal of medicinal chemistry 2022-04-28
90 A Bayesian Model with Application for Adaptive Platform Trials Having Temporal Changes
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Abstract: Temporal changes exist in clinical trials. Over time, shifts in patients’ characteristics, trial conduct, and other features of a clinical trial may occur. In typical randomized …		 Chenguang Wang; Min Lin; Gary L Rosner; Guoxing Soon; Biometrics 2022-04-27
91 Contributions of The Regional Emerging Special Pathogen Treatment Centers to The US COVID-19 Pandemic Response
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Abstract: The National Emerging Special Pathogens Training and Education Center (NETEC) was established in 2015 to improve the capabilities of healthcare facilities to provide safe and …		 JONATHAN D GREIN et. al. Health security 2022-04-27
92 A Cryptic Pocket in Ebola VP35 Allosterically Controls RNA Binding
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Abstract: Protein-protein and protein-nucleic acid interactions are often considered difficult drug targets because the surfaces involved lack obvious druggable pockets. Cryptic pockets …		 MATTHEW A CRUZ et. al. Nature communications 2022-04-27
93 Ebola Virus VP35 Hijacks The PKA-CREB1 Pathway for Replication and Pathogenesis By AKIP1 Association
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Abstract: Ebola virus (EBOV), one of the deadliest viruses, is the cause of fatal Ebola virus disease (EVD). The underlying mechanism of viral replication and EBOV-related hemorrhage is not …		 LIN ZHU et. al. Nature communications 2022-04-26
94 Efficacy of Disinfectants for Inactivation of Ebola Virus in Suspension By Integrated Cell Culture Coupled with Real-time RT-PCR
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Abstract: Ebola virus can be transmitted by contact with environmental surfaces (fomites) contaminated with secretions and excretions from infected individuals. Due to their potential to …		 Y Huang; S Xiao; D Song; Z Yuan; The Journal of hospital infection 2022-04-25
95 ‘Convalescent Plasma’- An Effective Treatment Option to Prevent Emerging NCOVID-19- A Review
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Highlight: In this review article, we pointed out the background, rationality, mechanisms, and safety outcomes of CP to treat nCOVID-19 infected patients.		 SUMEL ASHIQUE et. al. Infectious disorders drug targets 2022-04-25
96 Improved Database Filtering Technology Enables More Efficient Ab Initio Design of Potent Peptides Against Ebola Viruses
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Abstract: The rapid mutations of viruses such as SARS-CoV-2 require vaccine updates and the development of novel antiviral drugs. This article presents an improved database filtering …		 THOMAS RIPPERDA et. al. Pharmaceuticals (Basel, Switzerland) 2022-04-24
97 Evaluation of The Toxicological Effects of Favipiravir (T-705) on Liver and Kidney in Rats: Biochemical and Histopathological Approach
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Abstract: Favipiravir is a selective RNA polymerase inhibitor and a broad-spectrum antiviral drug, an important agent used in viral infections, including Ebola, Lassa, and COVID-19. This …		 ADEM KARA et. al. Drug and chemical toxicology 2022-04-21
98 Plasma Proteomic Analysis Distinguishes Severity Outcomes of Human Ebola Virus Disease
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Abstract: Ebola virus (EBV) disease (EVD) is a highly virulent systemic disease characterized by an aggressive systemic inflammatory response and impaired vascular and coagulation systems, …		 ARTHUR VIODÉ et. al. mBio 2022-04-21
99 Contextualizing Mobility During The Ebola Epidemic in Liberia
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Abstract: Based on findings from focus groups and key informant interviews conducted at five sites in Liberia between 2018 and 2019, we explore some of the key factors that influenced …		 MOSOKA FALLAH et. al. PLoS neglected tropical diseases 2022-04-20
100 Risk Factors for Ebola Virus Disease Among Household Care Providers, Sierra Leone, 2015
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Abstract: Household contacts who provide care to an Ebola virus disease (EVD) case have a 3-fold higher risk of EVD compared with contacts who do not provide care. We enrolled persons with …		 NADEZHDA DUFFY et. al. International journal of epidemiology 2022-04-20
101 Deciphering The Assembly of Enveloped Viruses Using Model Lipid Membranes
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Abstract: The cell plasma membrane is mainly composed of phospholipids, cholesterol and embedded proteins, presenting a complex interface with the environment. It maintains a barrier to …		 Erwan Brémaud; Cyril Favard; Delphine Muriaux; Membranes 2022-04-19
102 One-step Single-tube Accelerated Quantitative Nucleoprotein Gene-specific Reverse Transcription Loop-mediated Isothermal Gene Amplification (RT-LAMP) Assay for Rapid, Real-time & Reliable Clinical Detection of Ebola Virus
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Abstract: Due to the absence of specific drugs or vaccines for Ebola virus disease, rapid, sensitive and reliable diagnostic methods are required to control the transmission chain of the …		 JYOTI S KUMAR et. al. The Indian journal of medical research 2022-04-18
103 Pesticide Importation in Sierra Leone, 2010-2021: Implications for Food Production and Antimicrobial Resistance
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Abstract: There are no previous studies reporting the type and quantity of pesticides for farming from Sierra Leone and the impact of Ebola or COVID-19 on importation. This study reviewed …		 RAYMONDA A B JOHNSON et. al. International journal of environmental research and public … 2022-04-15
104 Unique Mode of Antiviral Action of A Marine Alkaloid Against Ebola Virus and SARS-CoV-2
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Abstract: Lamellarin α 20-sulfate is a cell-impenetrable marine alkaloid that can suppress infection that is mediated by the envelope glycoprotein of human immunodeficiency virus type 1. We …		 MAI IZUMIDA et. al. Viruses 2022-04-15
105 Misconceptions and Rumors About Ebola Virus Disease in Sub-Saharan Africa: A Systematic Review
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Abstract: We sought to summarize knowledge, misconceptions, beliefs, and practices about Ebola that might impede the control of Ebola outbreaks in Africa. We searched Medline, EMBASE, …		 BASILUA ANDRE MUZEMBO et. al. International journal of environmental research and public … 2022-04-13
106 Ebola Virus: DRC Field Laboratories’ Rapid Response
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 Daniel Mukadi-Bamuleka; Steve Ahuka-Mundeke; Kevin K Ariën; Nature 2022-04-13
107 Complement-Mediated Neutralisation Identified in Ebola Virus Disease Survivor Plasma: Implications for Protection and Pathogenesis
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Abstract: The 2013-2016 Ebola virus (EBOV) epidemic in West Africa was unprecedented in case numbers and fatalities, and sporadic outbreaks continue to arise. Antibodies to the EBOV …		 JACK MELLORS et. al. Frontiers in immunology 2022-04-12
108 Ebola Virus Entry Inhibitors
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Highlight: In this chapter, we describe the current understanding of the EBOV entry process and summarize the approaches, strategies, and advances in discovery and development of EBOV entry inhibitors, including therapeutic antibodies, peptides, small molecules, natural products, and other chemical structures.		 Ruikun Du; Qinghua Cui; Michael Caffrey; Lijun Rong; Advances in experimental medicine and biology 2022-04-12
109 CAPG Is Required for Ebola Virus Infection By Controlling Virus Egress from Infected Cells
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Highlight: Here, we identified the actin-regulating protein, CAPG, as important for EBOV replication.		 H. MORI et. al. bio.microbiology 2022-04-11
110 Comparison of Aerosol Stability of Different Variants of Ebola Virus and Marburg Virus and Virulence of Aerosolised Ebola Virus in An Immune-Deficient Mouse
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Abstract: During outbreaks of virus diseases, many variants may appear, some of which may be of concern. Stability in an aerosol of several Ebola virus and Marburg virus variants was …		 Sophie J Smither; Lin S Eastaugh; Mark S Lever; Viruses 2022-04-09
111 Treatment with Ad5-Porcine Interferon-α Attenuates Ebolavirus Disease in Pigs
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Abstract: Under experimental conditions, pigs infected with Ebola Virus (EBOV) develop disease and can readily transmit the virus to non-human primates or pigs. In the event of accidental …		 CHANDRIKA SENTHILKUMARAN et. al. Pathogens (Basel, Switzerland) 2022-04-08
112 Spatially-heterogeneous Embedded Stochastic SEIR Models for The 2014-2016 Ebola Outbreak in West Africa
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Abstract: The dynamics of human infectious diseases are challenging to understand, particularly when a pathogen spreads spatially over a large region. We present a stochastic, …		 Kaitlyn Martinez; Grant Brown; Stephen Pankavich; Spatial and spatio-temporal epidemiology 2022-04-07
113 STAT1 and Its Crucial Role in The Control of Viral Infections
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Abstract: The signal transducer and activator of transcription (STAT) 1 protein plays a key role in the immune response against viruses and other pathogens by transducing, in the nucleus, …		 Manlio Tolomeo; Andrea Cavalli; Antonio Cascio; International journal of molecular sciences 2022-04-07
114 Virus Detection: From State-of-the-Art Laboratories to Smartphone-Based Point-of-Care Testing
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Abstract: Infectious virus outbreaks pose a significant challenge to public healthcare systems. Early and accurate virus diagnosis is critical to prevent the spread of the virus, especially …		 MENG XIAO et. al. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022-04-07
115 TIM-1 Augments Cellular Entry of Ebola Virus Species and Mutants, Which Is Blocked By Recombinant TIM-1 Protein
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Abstract: Ebola virus, a member of the family, utilizes the attachment factors on host cells to support its entry and cause severe tissue damage. TIM-1 has been identified as a predominant …		 MIN ZHANG et. al. Microbiology spectrum 2022-04-06
116 Prospective Asian Plants with Corroborated Antiviral Potentials: Position Standing in Recent Years
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Highlight: Modern drug discovery and development techniques offer highly efficient separation techniques, inauguration of vector-based schemes where the original infectious virus is cloned to the non-infectious one for antiviral screening targets. The objective of the review was to gather available data on 20 both cultivated and native plants of Asia giving antiviral activities and provide comprehensive information on the phytochemical analysis of the plants and potential antiviral compounds isolated from these plants.		 Sania Ashrafi; Mamunur Rahman; Pollob Ahmed; Safaet Alam; Md Abid Hossain; Beni-Suef University journal of basic and applied sciences 2022-04-05
117 Comparative Analyses of Small Molecule and Antibody Inhibition on Glycoprotein-mediated Entry of Měnglà Virus with Other Filoviruses
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Abstract: The ability of viruses in the Filoviridae family (Ebola virus [EBOV] and Marburg virus [MARV]) to cause severe human disease and their pandemic potential makes all emerging …		 Laura Cooper; Jazmin Galvan Achi; Lijun Rong; Journal of medical virology 2022-04-05
118 Molnupiravir and Its Antiviral Activity Against COVID-19
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Abstract: The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) constitutes a major worldwide public health threat and …		 LILI TIAN et. al. Frontiers in immunology 2022-04-04
119 Strategies in Medicinal Chemistry to Discovery New Hits Compounds Against Ebola Virus: Challenges and Perspectives in Drug Discovery
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Highlight: In sense, more investments are needed in the research focused on the development of new antiviral drugs.		 Igor José Dos Santos Nascimento; Paulo Fernando da Silva Santos-Júnior; João Xavier de Araújo-Júnior; Edeildo Ferreira da Silva-Júnior; Mini reviews in medicinal chemistry 2022-04-04
120 Understanding One Health Through Biological and Behavioral Risk Surveillance in Liberia: A Cross-sectional Study
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Highlight: The project used a One Health biological-behavioral surveillance approach that included catch-and-release wildlife sampling and behavioral risk surveys.		 SANDRA SAMUELS et. al. The Lancet. Global health 2022-04-01
121 Analysis of Individual-level Data from 2018-2020 Ebola Outbreak in Democratic Republic of The Congo
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Abstract: The 2018-2020 Ebola virus disease epidemic in Democratic Republic of the Congo (DRC) resulted in 3481 cases (probable and confirmed) and 2299 deaths. In this paper, we use a novel …		 HARLEY VOSSLER et. al. Scientific reports 2022-04-01
122 Protein Folding Interdiction Strategy for Therapeutic Drug Development in Viral Diseases: Ebola VP40 and Influenza A M1
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Abstract: In a recent paper, we proposed the folding interdiction target region (FITR) strategy for therapeutic drug design in SARS-CoV-2. This paper expands the application of the FITR …		 Fernando Bergasa-Caceres; Herschel A Rabitz; International journal of molecular sciences 2022-03-31
123 Evaluation of Phenol-Substituted Diphyllin Derivatives As Selective Antagonists for Ebola Virus Entry
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Abstract: Ebola virus (EBOV) is an aggressive filoviral pathogen that can induce severe hemorrhagic fever in humans with up to 90% fatality rate. To date, there are no clinically effective …		 CAROLINE B PLESCIA et. al. ACS infectious diseases 2022-03-31
124 Multifunctional Role of Exosomes in Viral Diseases: From Transmission to Diagnosis and Therapy
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Abstract: Efforts to discover antiviral drugs and diagnostic platforms have intensified to an unprecedented level since the outbreak of COVID-19. Nano-sized endosomal vesicles called …		 Pinal Chaudhari; Vivek Ghate; Madhavan Nampoothiri; Shaila Lewis; Cellular signalling 2022-03-31
125 Implementing A DHIS2 Ebola Virus Disease Module During The 2021 Guinea Ebola Outbreak
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Abstract: In 2017, the national agency for health security (L’Agence Nationale de Sécurité Sanitaire-ANSS) in Guinea implemented the District Health Information Software (DHIS2) as the …		 CARRIE EGGERS et. al. BMJ global health 2022-03-31
126 Inferring The Reproduction Number Using The Renewal Equation in Heterogeneous Epidemics
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Highlight: In this paper, we derive a multi-type equivalent to the renewal equation to estimate a reproduction number which accounts for heterogeneity in transmissibility including through asymptomatic transmission, symptomatic isolation and vaccination.		 William Green; Neil Ferguson; Anne Cori; Journal of the Royal Society, Interface 2022-03-30
127 Protective CD8+ T Cell Response Induced By Modified Vaccinia Virus Ankara Delivering Ebola Virus Nucleoprotein
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Abstract: The urgent need for vaccines against Ebola virus (EBOV) was underscored by the large outbreak in West Africa (2014-2016). Since then, several promising vaccine candidates have …		 ALEXANDRA KUPKE et. al. Vaccines 2022-03-29
128 Contesting The Crisis Narrative: Epidemic Accounts in Sierra Leone, Democratic Republic of Congo, and Tanzania
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Highlight: This paper draws on accounts in Tanzania, Sierra Leone and Democratic Republic of Congo to contrast global catastrophe framings with everyday imaginations and experiences of crisis and crisis management.		 Shelley Lees; Luisa Enria; Myfanwy James; Disasters 2022-03-29
129 Incidence of Surgical Site Infection and Use of Antibiotics Among Patients Who Underwent Caesarean Section and Herniorrhaphy at A Regional Referral Hospital, Sierra Leone
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Abstract: Surgical site infections (SSIs) are common postoperative complications. Surgical antibiotic prophylaxis (SAP) can prevent the occurrence of SSIs if administered appropriately. We …		 RONALD CARSHON-MARSH et. al. International journal of environmental research and public … 2022-03-29
130 Factors Responsible for The Emergence of Novel Viruses: An Emphasis on SARS-CoV-2
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Abstract: Structural and genetic differences among various viruses play a significant factor in host infectivity and vulnerability to environmental stressors. Zoonoses of viruses require …		 Sanjeeb Mohapatra; N Gayathri Menon; Current opinion in environmental science & health 2022-03-28
131 An Update of Antispike Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Monoclonal Antibodies
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Abstract: The use of monoclonal antibodies has expanded beyond the realm of autoimmune disease and cancer therapeutics to communicable diseases. Their antiviral activities were evaluated in …		 Suparna Chatterjee; Shouvik Choudhury; Debaleena Das; Indian journal of pharmacology 2022-03-28
132 Antibody Use During An Outbreak of Ebola Virus Disease in The Democratic Republic of Congo, 2020
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 Sabue Mulangu; Placide Mbala-Kingebeni; Olivier T Mbaya; The New England journal of medicine 2022-03-23
133 Identification of Novel Ebola Virus Inhibitors Using Biologically Contained Virus
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Abstract: Despite recent advancements in the development of vaccines and monoclonal antibody therapies for Ebola virus disease, treatment options remain limited. Moreover, management and …		 BERT VANMECHELEN et. al. Antiviral research 2022-03-23
134 The Repeated Setbacks of HIV Vaccine Development Laid The Groundwork for SARS-CoV-2 Vaccines
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Abstract: The decades-long effort to produce a workable HIV vaccine has hardly been a waste of public and private resources. To the contrary, the scientific know-how acquired along the way …		 Jeffrey E Harris; Health policy and technology 2022-03-21
135 The Feline Calicivirus Leader of The Capsid Protein Has The Functional Characteristics of A Viroporin
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Abstract: The leader of the capsid (LC) protein is exclusive to the genus, and it is needed for successful feline calicivirus (FCV) replication, as well as an efficient apoptosis induction …		 Yoatzin Peñaflor-Téllez; Bibiana Chávez-Munguía; Anel Lagunes-Guillén; Lizbeth Salazar-Villatoro; Ana Lorena Gutiérrez-Escolano; Viruses 2022-03-18
136 Nasal Carriage of Methicillin-Resistant Staphylococcus Aureus Among Sympatric Free-ranging Domestic Pigs and Wild Chlorocebus Pygerythrus in A Rural African Setting
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Abstract: Methicillin Resistant Staphylococcus aureus (MRSA) nasal carriage in domestic pigs and vervet monkeys is a risk factor for subsequent severe infections in domestic pigs and for …		 John Bosco Kalule; Valeria Zalwango Nakintu; Simon Peter SSendawula; BMC veterinary research 2022-03-16
137 Recurrent Ebola Outbreaks in The Eastern Democratic Republic of The Congo: A Wake-up Call to Scale Up The Integrated Disease Surveillance and Response Strategy
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Abstract: Ebola virus disease (EVD) is a dangerous viral zoonotic hemorrhagic fever caused by a deadly pathogenic filovirus. Frugivorous bats are recognized as being the natural reservoir, …		 Olivier Kambere Kavulikirwa; Franck Katembo Sikakulya; One health (Amsterdam, Netherlands) 2022-03-15
138 Impact of The Ebola Virus Outbreak on Tuberculosis Treatment Adherence and Outcomes in A Military Hospital in Freetown, Sierra Leone
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Abstract: The impact and disruption of infectious disease outbreaks stretch far beyond their direct death toll, as they often overburden health systems, reduce treatment seeking behaviors, …		 KATHRYN M HOGAN et. al. The American journal of tropical medicine and hygiene 2022-03-14
139 The Ebola Virus Matrix Protein Clusters Phosphatidylserine, A Critical Step in Viral Budding
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Highlight: Here, we describe the ability of the Ebola virus (EBOV) matrix protein eVP40 to induce clustering of PS and promote viral budding in vitro, as well as the ability of an FDA approved drug, fendiline, to reduce PS clustering subsequently reducing virus budding and entry.		 M. L. HUSBY et. al. bio.microbiology 2022-03-14
140 Rescuing Low Frequency Variants Within Intra-host Viral Populations Directly from Oxford Nanopore Sequencing Data
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Abstract: Infectious disease monitoring on Oxford Nanopore Technologies (ONT) platforms offers rapid turnaround times and low cost. Tracking low frequency intra-host variants provides …		 YUNXI LIU et. al. Nature communications 2022-03-14
141 COVID-19 in Africa: Rethinking The Tools to Manage Future Pandemics
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Abstract: Corona virus disease 2019 (COVID-19) remains an incurable, progressive pneumonia-like illness characterized by fever, dry cough, fatigue, and headache during its early stages. …		 Ismaila Emahi; Mimmie Cnc Watts; Samuel Azibere; Joseph F Morrison; Kwabena An Sarpong; African health sciences 2022-03-14
142 Germs, Guns, and Fear in Disaster Response: A Rapid Qualitative Assessment to Understand Fear-Based Responses in The Population at Large: Lessons From Sierra Leone 2014-2015
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Abstract: We set out to assess the feasibility of community-focused randomized qualitative assessment at the start of an emergency to identify the root causes of fear-based responses …		 Cora P Nally; Patrick Van de Voorde; Marleen Temmerman; Mary Adam; Disaster medicine and public health preparedness 2022-03-14
143 Spatial Model of Ebola Outbreaks Contained By Behavior Change
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Abstract: The West African Ebola (2014-2016) epidemic caused an estimated 11.310 deaths and massive social and economic disruption. The epidemic was comprised of many local outbreaks of …		 Gustav S Halvorsen; Lone Simonsen; Kim Sneppen; PloS one 2022-03-14
144 Immunization Against Severe Acute Respiratory Syndrome Coronavirus 2: An Overview
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Abstract: In the past years, numerous new fatal infections have emerged, including Ebola, Nipah, and Zika viruses, as well as coronaviruses. Recently, infections with severe acute …		 Eman A El-Masry; African health sciences 2022-03-14
145 Field Performance of Three Ebola Rapid Diagnostic Tests Used During The 2018-20 Outbreak in The Eastern Democratic Republic of The Congo: A Retrospective, Multicentre Observational Study
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Abstract: The Democratic Republic of the Congo has confronted 13 outbreaks of Ebola virus disease since 1976. Rapid diagnostic tests (RDTs) detecting viral antigens have been developed to …		 DANIEL MUKADI-BAMULEKA et. al. The Lancet. Infectious diseases 2022-03-14
146 Human Adenovirus Type 26 Basic Biology and Its Usage As Vaccine Vector
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Abstract: Due to their nature, adenoviruses have been recognised as promising candidates for vaccine vector development. Since they mimic natural infection, recombinant adenovirus vectors …		 Dragomira Majhen; Reviews in medical virology 2022-03-12
147 VSV-Based Vaccines Reduce Virus Shedding and Viral Load in Hamsters Infected with SARS-CoV-2 Variants of Concern
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Abstract: The continued progression of the COVID-19 pandemic can partly be attributed to the ability of SARS-CoV-2 to mutate and introduce new viral variants. Some of these variants with …		 KYLE L O’DONNELL et. al. Vaccines 2022-03-12
148 On The Possibility of Oscillating in The Ebola Virus Dynamics and Investigating The Effect of The Lifetime of T Lymphocytes
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Abstract: Ebola virus (EBOV) targets immune cells and tries to inactivate dendritic cells and interferon molecules to continue its replication process. Since EBOV detailed mechanism has not …		 Mehrdad Ghaemi; Mina Shojafar; Zahra Zabihinpour; Yazdan Asgari; PloS one 2022-03-11
149 Therapeutic Strategies Against Ebola Virus Infection
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Abstract: Since the 2014-2016 epidemic, Ebola virus (EBOV) has spread to several countries and has become a major threat to global health. EBOV is a risk group 4 pathogen, which imposes …		 Ching-Hsuan Liu; Yee-Tung Hu; Shu Hui Wong; Liang-Tzung Lin; Viruses 2022-03-11
150 The Road to Effective and Accessible Antibody Therapies Against Ebola Virus
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Abstract: Ebola virus (EBOV) outbreaks can claim thousands of lives, cripple healthcare systems and local economies. Effective vaccines and treatments against EBOV are therefore needed to …		 Hugues Fausther-Bovendo; Gary Kobinger; Current opinion in virology 2022-03-11
151 Pandemic-induced Economic Policy Uncertainty and US Stock Exchanges
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Abstract: This study investigates the impacts of pandemic-induced economic policy uncertainties (PIEPU) on the S&P500, Nasdaq-100, and Dow Jones indexes (stock returns). To this aim, for …		 Serdar Ongan; Ismet Gocer; Ayse Ongan; Journal of public affairs 2022-03-11
152 Qualitative Evidence Syntheses of Attitudes and Preferences to Inform Guidelines on Infant Feeding in The Context of Ebola Virus Disease (EVD) Transmission Risk
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Abstract: Breast-feeding holds considerable potential to reduce infant mortality. Feeding choices, already complex, take on additional complexity against a backdrop of the risk of …		 Fiona Campbell; Andrew Booth; Christopher Carroll; Andrew Lee; Clare Relton; PLoS neglected tropical diseases 2022-03-10
153 Dynamics of Antibodies to Ebolaviruses in An Eidolon Helvum Bat Colony in Cameroon
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Abstract: The ecology of ebolaviruses is still poorly understood and the role of bats in outbreaks needs to be further clarified. Straw-colored fruit bats ( ) are the most common fruit bats …		 DOWBISS META DJOMSI et. al. Viruses 2022-03-09
154 Reovirus Infection Is Regulated By NPC1 and Endosomal Cholesterol Homeostasis
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Abstract: Cholesterol homeostasis is required for the replication of many viruses, including Ebola virus, hepatitis C virus, and human immunodeficiency virus-1. Niemann-Pick C1 (NPC1) is an …		 PAULA ORTEGA-GONZALEZ et. al. PLoS pathogens 2022-03-09
155 The Development of Broad-spectrum Antiviral Medical Countermeasures to Treat Viral Hemorrhagic Fevers Caused By Natural or Weaponized Virus Infections
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Abstract: The Joint Program Executive Office for Chemical, Biological, Radiological, and Nuclear Defense (JPEO-CBRND) began development of a broad-spectrum antiviral countermeasure against …		 Mark R Hickman; David L Saunders; Catherine A Bigger; Christopher D Kane; Patrick L Iversen; PLoS neglected tropical diseases 2022-03-08
156 Protocol for A Phase 3 Trial to Evaluate The Effectiveness and Safety of A Heterologous, Two-dose Vaccine for Ebola Virus Disease in The Democratic Republic of The Congo
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Abstract: Ebola virus disease (EVD) continues to be a significant public health problem in sub-Saharan Africa, especially in the Democratic Republic of the Congo (DRC). Large-scale …		 DEBORAH WATSON-JONES et. al. BMJ open 2022-03-08
157 Association of Lower Exposure Risk With Paucisymptomatic/Asymptomatic Infection, Less Severe Disease, and Unrecognized Ebola Virus Disease: A Seroepidemiological Study
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Abstract: It remains unclear if there is a dose-dependent relationship between exposure risk to Ebola virus (EBOV) and severity of illness. From September 2016 to July 2017, we conducted a …		 J DANIEL KELLY et. al. Open forum infectious diseases 2022-03-07
158 Tweeting Jokes, Tweeting Hope: Humor Practices During The 2014 Ebola Outbreak
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Abstract: In this article, we examine how humor practices on Twitter resist dominant emotion norms during an emerging disease outbreak. Humor may seem frivolous or irreverent but can …		 Marci D Cottingham; Ariana Rose; Health communication 2022-03-07
159 Crosstalk Between RNA Viruses and DNA Sensors: Role of The CGAS-STING Signalling Pathway
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Abstract: Despite only comprising half of all known viral species, RNA viruses are disproportionately responsible for many of the worst epidemics in human history, including outbreaks of …		 Yiyun Michelle Fan; Yizhuo Lyanne Zhang; Honglin Luo; Yasir Mohamud; Reviews in medical virology 2022-03-07
160 Structural Insight Into Marburg Virus Nucleoprotein-RNA Complex Formation
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Abstract: The nucleoprotein (NP) of Marburg virus (MARV), a close relative of Ebola virus (EBOV), encapsidates the single-stranded, negative-sense viral genomic RNA (vRNA) to form the …		 YOKO FUJITA-FUJIHARU et. al. Nature communications 2022-03-04
161 Using Next Generation Matrices to Estimate The Proportion of Cases That Are Not Detected in An Outbreak
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Highlight: In this paper, we present a method for estimating the proportion of infections that are not detected during an outbreak.		 H. J. T. UNWIN et. al. med.epidemiology 2022-03-03
162 Isoquercetin As An Anti-Covid-19 Medication: A Potential to Realize
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Abstract: Isoquercetin and quercetin are secondary metabolites found in a variety of plants, including edible ones. Isoquercetin is a monoglycosylated derivative of quercetin. When …		 Majambu Mbikay; Michel Chrétien; Frontiers in pharmacology 2022-03-02
163 Molecular Tweezers – A New Class of Potent Broad-spectrum Antivirals Against Enveloped Viruses
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Abstract: A new supramolecular approach to broad spectrum antivirals utilizes host guest chemistry between molecular tweezers and lysine/arginine as well as choline. Basic amino acids in …		 My-Hue Le; Estelle S Taghuo K; Thomas Schrader; Chemical communications (Cambridge, England) 2022-03-01
164 Findings and Implications From An Evaluation of The Gold Star Campaign in Post-Ebola Guinea: The Role of Gender and Education
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Abstract: In post-Ebola Guinea, the Health Communication Capacity Collaborative (HC3) project worked to rebuild trust in the health system and increase the utilization of reproductive, …		 Tilly Gurman; Darriel Harris; Sidikiba Sidibé; Global health, science and practice 2022-02-28
165 The Salience of Trust to The Client-Provider Relationship in Post-Ebola Guinea: Findings From A Qualitative Study
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Abstract: Lack of trust in the health care system can serve as a barrier to service utilization, especially in pandemic and postemergency settings. Although previous research has identified …		 NATALIE TIBBELS et. al. Global health, science and practice 2022-02-28
166 The Analogs of Furanyl Methylidene Rhodanine Exhibit Broad-Spectrum Inhibitory and Inactivating Activities Against Enveloped Viruses, Including SARS-CoV-2 and Its Variants
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Abstract: In recent years, infectious diseases caused by viral infections have seriously endangered human health, especially COVID-19, caused by SARS-CoV-2, which continues to spread …		 JING PU et. al. Viruses 2022-02-27
167 Ebola Entry Inhibitors Discovered from Maesa Perlarius
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Abstract: Ebola virus disease (EVD), a disease caused by infection with Ebola virus (EBOV), is characterized by hemorrhagic fever and a high case fatality rate. With limited options for the …		 Nga Yi Tsang; Wan-Fei Li; Elizabeth Varhegyi; Lijun Rong; Hong-Jie Zhang; International journal of molecular sciences 2022-02-27
168 Vaccine Licensure in The Absence of Human Efficacy Data
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Abstract: Clinical vaccine development and regulatory approval generally occurs in a linear, sequential manner: Phase 1: safety, immunogenicity; Phase 2: immunogenicity, safety, dose …		 COURTNEY L FINCH et. al. Vaccines 2022-02-26
169 Identification of Novel Chemical Compounds Targeting Filovirus VP40-mediated Particle Production
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Abstract: The central role of Ebola virus (EBOV) VP40 in nascent virion assembly and budding from infected host cells makes it an important therapeutic target. The mechanism of …		 SHUZO URATA et. al. Antiviral research 2022-02-25
170 Case Report: COVID-19 and Lassa Fever Coinfection in An Ebola Suspected Patient in Guinea
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Abstract: In this case report, we describe a clinical presentation and therapeutic history of a unique case diagnosed with Lassa fever and severe acute respiratory syndrome coronavirus 2 …		 MORY KEITA et. al. The American journal of tropical medicine and hygiene 2022-02-25
171 Use of Ebola Vaccine: Expansion of Recommendations of The Advisory Committee on Immunization Practices To Include Two Additional Populations – United States, 2021
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Abstract: On December 19, 2019, the Food and Drug Administration (FDA) approved rVSVΔG-ZEBOV-GP Ebola vaccine (ERVEBO, Merck) for the prevention of Ebola virus disease (EVD) caused by …		 JASON H MALENFANT et. al. MMWR. Morbidity and mortality weekly report 2022-02-25
172 Ebola Virus Glycoprotein IgG Seroprevalence in Community Previously Affected By Ebola, Sierra Leone
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Abstract: We explored the association of Ebola virus antibody seropositivity and concentration with potential risk factors for infection. Among 1,282 adults and children from a community …		 DANIELA MANNO et. al. Emerging infectious diseases 2022-02-24
173 Revival of The Heterologous Prime-boost Technique in COVID-19: An Outlook from The History of Outbreaks
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Abstract: The heterologous prime-boost vaccination technique is not novel as it has a history of deployment in previous outbreaks. Hence, this narrative review aims to provide critical …		 AMNA SIDDIQUI et. al. Health science reports 2022-02-23
174 Global Challenges in Preparedness and Response to Epidemic Infectious Diseases
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Abstract: Lessons drawn from successes and failures with coronavirus disease 2019 (COVID-19) and Ebola virus disease (EVD) should help shaping a robust health innovation system for …		 Piero Olliaro; Els Torreele; Molecular therapy : the journal of the American Society of … 2022-02-23
175 The Utility and Sustainability of US Ebola Treatment Centers During The COVID-19 Pandemic
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Abstract: In response to the 2014-2016 West Africa Ebola virus disease (EVD) epidemic, the Centers for Disease Control and Prevention (CDC) designated 56 US hospitals as Ebola treatment …		 JOCELYN J HERSTEIN et. al. Infection control and hospital epidemiology 2022-02-22
176 First Laboratory Confirmation and Sequencing of Zaire Ebolavirus in Uganda Following Two Independent Introductions of Cases from The 10th Ebola Outbreak in The Democratic Republic of The Congo, June 2019
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Abstract: Uganda established a domestic Viral Hemorrhagic Fever (VHF) testing capacity in 2010 in response to the increasing occurrence of filovirus outbreaks. In July 2018, the neighboring …		 LUKE NYAKARAHUKA et. al. PLoS neglected tropical diseases 2022-02-22
177 Remdesivir and Human Milk: A Case Study
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Abstract: Remdesivir was originally developed to treat Ebola hemorrhagic fever, and its efficacy in treating coronavirus disease 2019 was detected during a preliminary analysis of a …		 YUKA SANO WADA et. al. Journal of human lactation : official journal of … 2022-02-21
178 Phosphoramidate Prodrugs Continue to Deliver, The Journey of Remdesivir (GS-5734) from RSV to SARS-CoV-2
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Abstract: Remdesivir (GS-5734) is a monophenol, 2-ethylbutylalanine phosphoramidate prodrug of a 1′-cyano-4-aza-7,9-dideazaadenosine C-nucleoside (GS-441524) that is FDA approved for the …		 Richard L Mackman; ACS medicinal chemistry letters 2022-02-21
179 Strategies for Disease Containment: A Biological-Behavioral-Intervention Computational Informatics Framework
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Abstract: In this study, we describe the development and use of a biological-behavior-intervention computational informatics framework that combines disease modelling for infectious virus …		 Eva K Lee; Yifan Liu; Fan Yuan; Ferdinand H Pietz; AMIA … Annual Symposium proceedings. AMIA Symposium 2022-02-21
180 Pharmacokinetics and Safety of The Nucleoside Analog Antiviral Drug Galidesivir Administered to Healthy Adult Subjects
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Abstract: Galidesivir (BCX4430) is an adenosine nucleoside analog broadly active in cell culture against multiple RNA virus families, and active in animal models of viral diseases …		 AMANDA MATHIS et. al. Clinical pharmacology in drug development 2022-02-19
181 Added Value of An Anti-Ebola Serology for The Management of Clinically Suspect Ebola Virus Disease Patients Discharged As Negative in An Epidemic Context
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Abstract: Survivors from Ebola virus disease (EVD) may be at the origin of EVD resurgence. Simultaneous reactivity to at least two EBOV antigens was detected in 11/488 (2.3%, 95% CI …		 ANTOINE NKUBA-NDAYE et. al. The Journal of infectious diseases 2022-02-18
182 Polysaccharides and Their Derivatives As Potential Antiviral Molecules
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Abstract: In the current context of the COVID-19 pandemic, it appears that our scientific resources and the medical community are not sufficiently developed to combat rapid viral spread all …		 HADRIEN CLAUS-DESBONNET et. al. Viruses 2022-02-18
183 Best Practices of Highly Infectious Decedent Management: Consensus Recommendations from An International Expert Workshop
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Abstract: With the increasing number of highly infectious disease incidents, outbreaks, and pandemics in our society (e.g., Ebola virus disease, Lassa fever, coronavirus diseases), the need …		 AURORA B LE et. al. Journal of occupational and environmental hygiene 2022-02-16
184 Self-replicating Vehicles Based on Negative Strand RNA Viruses
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Abstract: Self-replicating RNA viruses have been engineered as efficient expression vectors for vaccine development for infectious diseases and cancers. Moreover, self-replicating RNA viral …		 Kenneth Lundstrom; Cancer gene therapy 2022-02-15
185 Tracking Ebolavirus Genomic Drift with A Resequencing Microarray
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Abstract: Filoviruses are emerging pathogens that cause acute fever with high fatality rate and present a global public health threat. During the 2013-2016 Ebola virus outbreak, genome …		 IRINA TIPER et. al. PloS one 2022-02-10
186 Ebola Virus Persistence and Disease Recrudescence in The Brains of Antibody-treated Nonhuman Primate Survivors
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Abstract: Effective therapeutics have been developed against acute Ebola virus disease (EVD) in both humans and experimentally infected nonhuman primates. However, the risk of viral …		 JUN LIU et. al. Science translational medicine 2022-02-09
187 Knowledge of Emerging and Reemerging Infectious Diseases in The Public of Guangzhou, Southern China
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Abstract: The objective of this study is to get the overall picture about the knowledge of emerging and reemerging infectious diseases in public in Guangzhou and provide a scientific basis …		 Xiaowei Ma; Jianyun Lu; Weisi Liu; Frontiers in public health 2022-02-08
188 Community-Institutional Partnerships to Strengthen Maternal Health Care: Case Study of The First Obstetrics and Gynecology Specialty Training Program in Liberia
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Abstract: Despite major setbacks to its health infrastructure and health workforce capacity, Liberia began its first post-graduate training program for physicians in 2013. Specialty …		 ANN MARIE BEDDOE et. al. Frontiers in public health 2022-02-07
189 Recombinant Lloviu Virus As A Tool to Study Viral Replication and Host Responses
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Abstract: Next generation sequencing has revealed the presence of numerous RNA viruses in animal reservoir hosts, including many closely related to known human pathogens. Despite their …		 ADAM J HUME et. al. PLoS pathogens 2022-02-04
190 The Effect of Ebola Virus Disease on Maternal Health Service Utilisation and Perinatal Outcomes in West Africa: A Systematic Review
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Abstract: Ebola outbreaks pose a major threat to global public health, especially in Sub-Saharan Africa. These outbreaks disrupt the already fragile maternal health services in West Africa. …		 Zemenu Yohannes Kassa; Vanessa Scarf; Deborah Fox; Reproductive health 2022-02-04
191 Antiviral Effects of Azithromycin: A Narrative Review
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Abstract: Viral infections have a great impact on human health. The urgent need to find a cure against different viruses led us to investigations in a vast range of drugs. Azithromycin …		 SAEED KHOSHNOOD et. al. Biomedicine & pharmacotherapy = Biomedecine & … 2022-02-04
192 Transient Dynamics of Infection Transmission in A Simulated Intensive Care Unit
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Abstract: Healthcare-associated infections (HAIs) remain a serious public health problem. In previous work, two models of an intensive care unit (ICU) showed that differing population …		 KATELIN C JACKSON et. al. PloS one 2022-02-03
193 Stepwise Enzymatic-Dependent Mechanism of Ebola Virus Binding to Cell Surface Receptors Monitored By AFM
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Abstract: Ebola virus (EBOV) is responsible for several outbreaks of hemorrhagic fever with high mortality, raising great public concern. Several cell surface receptors have been identified …		 QINGRONG ZHANG et. al. Nano letters 2022-02-02
194 Cross-sectional Study of Mental Health and Sexual Behaviours for Ebola Survivors in Beni, Butembo and Katwa Health Zones of The Democratic Republic of Congo
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Abstract: To understand the prevalence of mental health disorders in Ebola-affected communities and their association with condom use. Cross-sectional study. Beni, Butembo and Katwa health …		 Lynn Lieberman Lawry; Nancy Stroupe Kannappan; Covadonga Canteli; William Clemmer; BMJ open 2022-02-02
195 Transmission Models Indicate Ebola Virus Persistence in Non-human Primate Populations Is Unlikely
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Abstract: Infectious diseases that kill their hosts may persist locally only if transmission is appropriately balanced by susceptible recruitment. Great apes die of Ebola virus disease …		 David T S Hayman; Reju Sam John; Pejman Rohani; Journal of the Royal Society, Interface 2022-02-02
196 WWOX-Mediated Degradation of AMOTp130 Negatively Affects Egress of Filovirus VP40 Virus-Like Particles
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Abstract: Ebola virus (EBOV) and Marburg virus (MARV) continue to emerge and cause severe hemorrhagic disease in humans. A comprehensive understanding of the filovirus-host interplay will …		 Jingjing Liang; Gordon Ruthel; Bruce D Freedman; Ronald N Harty; Journal of virology 2022-02-02
197 Protective Behaviors Associated With Gender During The 2018-2020 Ebola Outbreak in Eastern Democratic Republic of The Congo
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Abstract: In 2018 to 2020, the Democratic Republic of the Congo experienced the world’s second largest Ebola virus disease (EVD) outbreak, killing 2290 individuals; women were …		 PHUONG N PHAM et. al. JAMA network open 2022-02-01
198 Current Perspective in Metal Oxide Based Photocatalysts for Virus Disinfection: A Review
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Abstract: Nanotechnology holds huge potential for the prevention of various viral outbreaks that have increased at a disquieting rate over the past decades. Metal oxide nanomaterials with …		 VATIKA SONI et. al. Journal of environmental management 2022-02-01
199 Drug Repurposing for SARS-CoV-2 Main Protease: Molecular Docking and Molecular Dynamics Investigations
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Abstract: The current novel corona virus illness (COVID-19) is a developing viral disease that was discovered in 2019. There is currently no viable therapeutic strategy for this illness …		 SAMIA E OMER et. al. Biochemistry and biophysics reports 2022-01-31
200 COVID-19 PANDEMIC AND ITS POTENTIAL IMPACT ON SEXUAL AND REPRODUCTIVE HEALTH INDICATORS IN NIGERIA
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Abstract: The impact of the novel corona virus disease (COVID-19) pandemic cuts across all sectors and has brought to the fore the true realities and status of health systems globally, …		 J O ADEYEMO et. al. Annals of Ibadan postgraduate medicine 2022-01-31
201 A Post-outbreak Assessment of Exposure Proximity and Ebola Virus Disease-related Stigma Among Community Members in Kono District, Sierra Leone: A Cross-sectional Study
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Abstract: Based on findings from other contexts, informed by intergroup contact theory, that more contact is associated with less stigma, we hypothesized that community members with greater …		 MICHELLE C DAVIDSON et. al. SSM. Mental health 2022-01-29
202 Community Trust of Government and Non-governmental Organizations During The 2014-16 Ebola Epidemic in Liberia
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Abstract: The West African Ebola Virus Disease epidemic of 2014-16 cost more than 11,000 lives. Interventions targeting key behaviors to curb transmission, such as safe funeral practices …		 RONAN F ARTHUR et. al. PLoS neglected tropical diseases 2022-01-27
203 Enterotoxigenic Escherichia Coli Heat-Stable Toxin and Ebola Virus Delta Peptide: Similarities and Differences
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Abstract: Enterotoxigenic (ETEC) STb toxin exhibits striking structural similarity to Ebola virus (EBOV) delta peptide. Both ETEC and EBOV delta peptide are enterotoxins. Comparison of the …		 Lilia I Melnik; Robert F Garry; Pathogens (Basel, Switzerland) 2022-01-27
204 ONTdeCIPHER: An Amplicon-based Nanopore Sequencing Pipeline for Tracking Pathogen Variants
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Abstract: Amplicon-based nanopore sequencing is increasingly used for molecular surveillance during epidemics (e.g. ZIKA, EBOLA) or pandemics (e.g. SARS-CoV-2). However, there is still a …		 EMIRA CHERIF et. al. Bioinformatics (Oxford, England) 2022-01-26
205 The Next Major Emergent Infectious Disease: Reflections on Vaccine Emergency Development Strategies
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Abstract: Major emergent infectious diseases (MEID) pose the most serious threat to human health. The research proposes targeted response strategies for the prevention and control of …		 YU BAI et. al. Expert review of vaccines 2022-01-26
206 Emerging Tropical Neurological Infections
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Abstract: A large majority of neurological infections remain undiagnosed worldwide. Emerging and re-emerging infections are likely to be responsible for a significant proportion of these. …		 Udaya K Ranawaka; Clinical medicine (London, England) 2022-01-26
207 Is There Anything Else You Would Like to Add?: The Ethics of (Not) Addressing Research Participants’ Top Concerns in Public Health Emergency Health Research
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Abstract: When conducting interviews or focus groups, researchers often end with a simple question; Is there anything else you would like to add? This article takes responses to this …		 Elysée Nouvet; Matthew Hunt; Lisa Schwartz; Frontiers in public health 2022-01-26
208 Postmortem Surveillance for Ebola Virus Using OraQuick Ebola Rapid Diagnostic Tests, Eastern Democratic Republic of The Congo, 2019-2020
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Abstract: After a pilot study, we tested 443 cadavers using OraQuick Ebola rapid diagnostic tests during surveillance after the 10th Ebola outbreak in the Democratic Republic of the Congo. …		 DANIEL MUKADI-BAMULEKA et. al. Emerging infectious diseases 2022-01-25
209 A Highly Attenuated Vesiculovax Vaccine Rapidly Protects Nonhuman Primates Against Lethal Marburg Virus Challenge
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Abstract: Background: Marburg virus (MARV), an Ebola-like virus, remains an eminent threat to public health as demonstrated by its high associated mortality rate (23-90%) and recent …		 C. WOOLSEY et. al. bio.microbiology 2022-01-23
210 High Doses of Favipiravir in Two Men Survivors of Ebola Virus Disease Carrying Ebola Virus in Semen in Guinea
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Abstract: Persistence of Ebola virus (EBOV) in semen remains of deep concern, as sexual transmission of EBOV seems plausible up to 6 months after acute phase of Ebola virus disease (EVD). …		 PHILIPPINE ELOY et. al. IDCases 2022-01-21
211 The Ring Vaccination Trial Design for The Estimation of Vaccine Efficacy and Effectiveness During Infectious Disease Outbreaks
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Abstract: The ring vaccination trial is a recently developed approach for evaluating the efficacy and effectiveness of vaccines, modeled after the surveillance and containment strategy of …		 Natalie E Dean; Ira M Longini; Clinical trials (London, England) 2022-01-21
212 A Systematic Review of Ebola Virus Disease Outbreaks and An Analysis of The Efficacy and Safety of Newer Drugs Approved for The Treatment of Ebola Virus Disease By The US Food and Drug Administration from 2016 to 2020
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Abstract: The Ebola virus has started to infect humans from time to time since then and has led to several outbreaks. Due to urbanisation growth, invasion of forested areas, and close …		 PALANISAMY SIVANANDY et. al. Journal of infection and public health 2022-01-21
213 Cocktail Party: Low-dose Antibody Combinations Deliver Pan-ebolavirus Protection
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Abstract: Recent outbreaks of Ebola have brought to the forefront the need for focused therapeutic treatments. In this issue of Cell, Milligan and colleagues build on previous studies of …		 Scott M Anthony; Lisa E Hensley; Cell 2022-01-20
214 Legume Lectins with Different Specificities As Potential Glycan Probes for Pathogenic Enveloped Viruses
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Abstract: Pathogenic enveloped viruses are covered with a glycan shield that provides a dual function: the glycan structures contribute to virus protection as well as host cell recognition. …		 ANNICK BARRE et. al. Cells 2022-01-20
215 Association Between Oral Antimalarial Medication Administration and Mortality Among Patients with Ebola Virus Disease: A Multisite Cohort Study
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Abstract: Empiric antimalarial treatment is a component of protocol-based management of Ebola virus disease (EVD), yet this approach has limited clinical evidence for patient-centered …		 LOGAN ABEL et. al. BMC infectious diseases 2022-01-20
216 Cynarin Blocks Ebola Virus Replication By Counteracting VP35 Inhibition of Interferon-beta Production
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Abstract: Ebola virus (EBOV) is one of the deadliest infective agents whose lethality is linked to the ability to efficiently bypass the host’s innate antiviral response. EBOV …		 ANGELA CORONA et. al. Antiviral research 2022-01-20
217 Disparities in Health Financing Allocation Among Infectious Diseases in Ebola Virus Disease (EVD)-Affected Countries, 2005-2017
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Abstract: The Ebola virus disease (EVD) outbreaks impacted the population health due to overstretched health systems and disrupted essential health services. Despite a call to achieve equal …		 Kazuki Shimizu; Francesco Checchi; Abdihamid Warsame; Healthcare (Basel, Switzerland) 2022-01-18
218 From Viral Evolution to Spatial Contagion: A Biologically Modulated Hawkes Model
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Abstract: Mutations sometimes increase contagiousness for evolving pathogens. During an epidemic, scientists use viral genome data to infer a shared evolutionary history and connect this …		 Andrew J Holbrook; Xiang Ji; Marc A Suchard; Bioinformatics (Oxford, England) 2022-01-18
219 Selective Estrogen Receptor Modulators Limit Alphavirus Infection By Targeting The Viral Capping Enzyme NsP1
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Abstract: Alphaviruses cause animal or human diseases that are characterized by febrile illness, debilitating arthralgia, or encephalitis. Selective estrogen receptor modulators (SERMs), a …		 RAJAT MUDGAL et. al. Antimicrobial agents and chemotherapy 2022-01-18
220 Health-related Quality of Life Among Ebola Survivors in Sierra Leone: The Role of Socio-demographic, Health-related and Psycho-social Factors
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Abstract: Evidence of how social factors affect the health-related quality of life (HRQoL) of Ebola virus disease (EVD) survivors is limited. Our study explores the association between …		 PETER BAI JAMES et. al. Health and quality of life outcomes 2022-01-15
221 The Role of Phosphatidylserine on The Membrane in Immunity and Blood Coagulation
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Abstract: The negatively charged aminophospholipid, phosphatidylserine (PtdSer), is located in the inner leaflet of the plasma membrane in normal cells, and may be exposed to the outer …		 JIAO WANG et. al. Biomarker research 2022-01-15
222 Pandemic Inequalities: Emerging Infectious Diseases and Health Equity
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Abstract: The frequency and scale of Emerging Infectious Diseases (EIDs) with pandemic potential has been increasing over the last two decades and, as COVID-19 has shown, such zoonotic …		 Clare Bambra; International journal for equity in health 2022-01-14
223 Ebola Virus GP Activates Endothelial Cells Via Host Cytoskeletal Signaling Factors
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Abstract: Ebola virus disease (EVD) is a lethal disease caused by the highly pathogenic Ebola virus (EBOV), and its major symptoms in severe cases include vascular leakage and hemorrhage. …		 Benedicte Mpia Moni; Yasuteru Sakurai; Jiro Yasuda; Viruses 2022-01-13
224 In Vivo Single-cell Profiling of LncRNAs During Ebola Virus Infection
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Highlight: This study provides novel insights into the roles that lncRNAs play in the host response to acute viral infection and paves the way for future lncRNA studies at single-cell resolution.		 L. SANTUS et. al. bio.genomics 2022-01-13
225 Ebola Virus Disease and Current Therapeutic Strategies: A Review
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Abstract: The Ebola virus disease is a severe hemorrhagic fever that affects humans and other primates. Ebola virus, the causative agent of the disease, is transmitted to humans from wild …		 KALLIOPI IO DIAKOU et. al. Advances in experimental medicine and biology 2022-01-13
226 Quantitative Analysis of Genomic Sequences of Virus RNAs Using A Metric-Based Algorithm
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Highlight: This work aims to study the virus RNAs using a novel accelerated algorithm on exploring any-length genomic fragments in sequences using Hamming distance between the binary-expressed RNA symbols and explored pattern characters.		 A. Belinsky; G. Kouzaev; bio.genomics 2022-01-12
227 Selective Estrogen Receptor Modulators Limit Alphavirus Infection By Targeting The Viral Capping Enzyme NsP1
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Highlight: Combining biochemical, cell culture-based studies, and in vivo analyses, we strongly argue that SERM compounds, or their derivatives, may provide for attractive therapeutic options against alphaviruses.		 R. MUDGAL et. al. bio.immunology 2022-01-12
228 Rapid Protection from COVID-19 in Nonhuman Primates Vaccinated Intramuscularly But Not Intranasally with A Single Dose of A Vesicular Stomatitis Virus-Based Vaccine
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Abstract: The ongoing pandemic of coronavirus (CoV) disease 2019 (COVID-19) continues to exert a significant burden on health care systems worldwide. With limited treatments available, …		 WAKAKO FURUYAMA et. al. mBio 2022-01-11
229 Safety and Immunogenicity of 2-dose Heterologous Ad26.ZEBOV, MVA-BN-Filo Ebola Vaccination in Children and Adolescents in Africa: A Randomised, Placebo-controlled, Multicentre Phase II Clinical Trial
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Abstract: Reoccurring Ebola outbreaks in West and Central Africa have led to serious illness and death in thousands of adults and children. The objective of this study was to assess safety, …		 ZACCHAEUS ANYWAINE et. al. PLoS medicine 2022-01-11
230 Prevalence and Risk Factors of Depression Symptoms Among Rural and Urban Populations Affected By Ebola Virus Disease in The Democratic Republic of The Congo: A Representative Cross-sectional Study
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Abstract: High mortality rates, anxiety and distress associated with Ebola virus disease (EVD) are risk factors for mood disorders in affected communities. This study aims to document the …		 JUDE MARY CÉNAT et. al. BMJ open 2022-01-11
231 Author Correction: Cryo-EM Structure of The Ebola Virus Nucleoprotein-RNA Complex at 3.6 Å Resolution
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 Yukihiko Sugita; Hideyuki Matsunami; Yoshihiro Kawaoka; Takeshi Noda; Matthias Wolf; Nature 2022-01-07
232 Therapeutic Spectrum of Piperine for Clinical Practice: A Scoping Review
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Abstract: Translation of traditional knowledge of herbs into a viable product for clinical use is still an uphill task. Piperine, a pungent alkaloid molecule derived from and possesses …		 SURAJ S YADAV et. al. Critical reviews in food science and nutrition 2022-01-07
233 Synthetic Nanobody-functionalized Nanoparticles for Accelerated Development of Rapid, Accessible Detection of Viral Antigens
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Abstract: Successful control of emerging infectious diseases requires accelerated development of fast, affordable, and accessible assays for wide implementation at a high frequency. This …		 XIAHUI CHEN et. al. Biosensors & bioelectronics 2022-01-06
234 Optimization of Single-Dose VSV-Based COVID-19 Vaccination in Hamsters
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Abstract: The ongoing COVID-19 pandemic has resulted in global effects on human health, economic stability, and social norms. The emergence of viral variants raises concerns about the …		 KYLE L O’DONNELL et. al. Frontiers in immunology 2022-01-06
235 Scientometric Analysis of Public Health Emergencies: 1994-2020
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Abstract: The purpose of this paper is to summarize the research hotspots and frontiers in the field of public health emergencies (PHE) between 1994-2020 through the scientometric analysis …		 Jing Liu; Yujie Wang; Qian Zhang; Jianxiang Wei; Haihua Zhou; International journal of environmental research and public … 2022-01-06
236 More Than A Gender Issue: Testis As A Distinctive HIV Reservoir and Its Implication for Viral Eradication
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Abstract: Early establishment of HIV reservoir represents the main impediment to an HIV cure. Mainly composed of infected memory CD4 T-cells and macrophages, HIV reservoirs are found in …		 Jean-Pierre Routy; Franck P Dupuy; John Lin; Stéphane Isnard; Methods in molecular biology (Clifton, N.J.) 2022-01-05
237 Ebola Virus Disease: Current Perception of Clinical Features, Diagnosis, Pathogenesis, and Therapeutics
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Abstract: Zoonotic transmission of highly pathogenic viruses, are a cause of deadly epidemics around the globe. These are of particular concern as evident from the recent global pandemic …		 Ruqaiyyah Siddiqui; Simal Khan; Naveed Ahmed Khan; Acta virologica 2022-01-03
238 A Protocol for A Scoping Review Comparative Bibliometric Analysis of Infectious Disease Research in Africa
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Abstract: Evidence on authorship trends of health research conducted about or in Africa shows that there is a lack of local researchers in the first and last authorship positions, with high …		 Adrianna Perryman; Gebremedhin Beedemariam Gebretekle; Adeteju Ogunbameru; Joanna M Bielecki; Beate Sander; Frontiers in public health 2022-01-03
239 Starting Points Matter: Cash Plus Training Effects on Youth Entrepreneurship, Skills, and Resilience During An Epidemic
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Abstract: This paper examines the impact of a “cash plus” intervention on youth entrepreneurship and skills formation during the Ebola crisis in Sierra Leone, using evidence from a …		 Nina Rosas; Maria Cecilia Acevedo; Samantha Zaldivar; World Development 2022-01-01
240 HIV-1 Trans -Infection Mediated By DCs: The Tip of The Iceberg of Cell-to-Cell Viral Transmission
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Abstract: HIV-1 cell-to-cell transmission is key for an effective viral replication that evades immunity. This highly infectious mechanism is orchestrated by different cellular targets that …		 DANIEL PEREZ-ZSOLT et. al. Pathogens (Basel, Switzerland) 2021-12-31
241 Natural History of Nonhuman Primates After Conjunctival Exposure to Ebola Virus
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Highlight: Historically, nonhuman primate (NHP) challenge studies have employed intramuscular or small particle aerosol exposure, which are uniformly lethal routes of infection, but mimic worst-case scenarios such as a needlestick.		 R. W. CROSS et. al. bio.microbiology 2021-12-30
242 Graphene-based Nanomaterials in Fighting The Most Challenging Viruses and Immunogenic Disorders
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Abstract: Viral diseases have long been among the biggest challenges for healthcare systems around the world. The recent Coronavirus Disease 2019 (COVID-19) pandemic is an example of how …		 Mahsa Ebrahimi; Mohamad Asadi; Omid Akhavan; ACS biomaterials science & engineering 2021-12-30
243 The Deuce-ace of Lassa Fever, Ebola Virus Disease and COVID-19 Simultaneous Infections and Epidemics in West Africa: Clinical and Public Health Implications
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Abstract: Globally, the prevailing COVID-19 pandemic has caused unprecedented clinical and public health concerns with increasing morbidity and mortality. Unfortunately, the burden of …		 NNABUEZE DARLINGTON NNAJI et. al. Tropical medicine and health 2021-12-30
244 S-palmitoylation and Sterol Interactions Mediate Antiviral Specificity of IFITM Isoforms
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Abstract: Interferon-induced transmembrane proteins (IFITM1, 2 and 3) are important antiviral proteins that are active against many viruses, including influenza A virus (IAV), dengue virus …		 TANDRILA DAS et. al. Research square 2021-12-29
245 Functional Interactomes of The Ebola Virus Polymerase Identified By Proximity Proteomics in The Context of Viral Replication
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Highlight: Here we leveraged proximity proteomics and conducted an siRNA screen to define the functional interactome of EBOV polymerase.		 J. FANG et. al. bio.microbiology 2021-12-28
246 The Discovery and Development of Novel Treatment Strategies for Filoviruses
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Abstract: Filoviruses are negative-stranded, enveloped RNA viruses that can cause hemorrhagic fever in humans and include Ebola and Marburg viruses. Lethality rates can reach 90% in …		 Steven B Bradfute; Expert opinion on drug discovery 2021-12-28
247 Rapid and Durable Protection Against Marburg Virus with A Single-Shot ChAd3-MARV GP Vaccine
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Highlight: To support regulatory approval of the ChAd3-Marburg vaccine that has completed Phase I trials, we show that a non-replicating chimpanzee-derived adenovirus vector with a demonstrated safety profile in humans (ChAd3) protected against a uniformly lethal challenge with Marburg-Angola.		 R. HUNEGNAW et. al. bio.immunology 2021-12-25
248 Extending Upon: What Effect Might Border Screening Have on Preventing Importation of COVID-19 Compared with Other Infections? – Considering The Additional Effect of Post-arrival Isolation
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Highlight: We recently described a simple model through which we assessed what effect subjecting travellers to a single on-arrival test might have on reducing risk of importing disease cases during simulated outbreaks of COVID-19, Influenza, SARS, and Ebola.		 D. Bays; E. Bennett; T. J. R. Finnie; med.public-and-global-health 2021-12-25
249 Potential Benefits of Antiviral African Medicinal Plants in The Management of Viral Infections: Systematic Review
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Abstract: Viruses cause various human diseases, some of which become pandemic outbreaks. This study synthesized evidence on antiviral medicinal plants in Africa which could potentially be …		 TAMIRAT BEKELE BERESSA et. al. Frontiers in pharmacology 2021-12-24
250 Multipurpose Drugs Active Against Both Plasmodium Spp. and Microorganisms: Potential Application for New Drug Development
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Abstract: Malaria, a disease caused by the protozoan parasites spp., is still causing serious problems in endemic regions in the world. Although the WHO recommends artemisinin combination …		 Takuro Endo; Hitoshi Takemae; Indu Sharma; Tetsuya Furuya; Frontiers in cellular and infection microbiology 2021-12-24
251 Mechanisms of Phosphatidylserine Influence on Viral Production: A Computational Model of Ebola Virus Matrix Protein Assembly
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Highlight: Here we used a computational model to evaluate EBOV matrix assembly.		 X. LIU et. al. bio.systems-biology 2021-12-23
252 Activity of Galidesivir in A Hamster Model of SARS-CoV-2
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Abstract: Coronavirus disease 2019 (COVID-19) has claimed the lives of millions of people worldwide since it first emerged. The impact of the COVID-19 pandemic on public health and the …		 RAY TAYLOR et. al. Viruses 2021-12-21
253 Pharmacologically Induced Endolysosomal Cholesterol Imbalance Through Clinically Licensed Drugs Itraconazole and Fluoxetine Impairs Ebola Virus Infection in Vitro
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Abstract: Ebola virus disease (EVD) is a severe and frequently lethal disease caused by Ebola virus (EBOV). The latest occasional EVD outbreak (2013-2016) in Western African, which was …		 SUSANN KUMMER et. al. Emerging microbes & infections 2021-12-17
254 CD47 Expression Attenuates Ebola Virus-induced Immunopathology in Mice
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Abstract: It has been shown that a very early cell-intrinsic response to infection is the upregulation of CD47 cell surface expression, a molecule known for delivering a don’t eat me …		 DEEPASHRI RAO et. al. Antiviral research 2021-12-17
255 Immunogenicity of RVSVΔG-ZEBOV-GP Ebola Vaccination in Exposed and Potentially Exposed Persons in The Democratic Republic of The Congo
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Abstract: Despite more than 300,000 rVSVΔG-ZEBOV-glycoprotein (GP) vaccine doses having been administered during Ebola virus disease (EVD) outbreaks in the Democratic Republic of the Congo …		 NICOLE A HOFF et. al. Proceedings of the National Academy of Sciences of the … 2021-12-17
256 An Optimal Control Model to Design Strategies for Reducing The Spread of The Ebola Virus Disease
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Abstract: In this work, we formulate an epidemiological model for studying the spread of Ebola virus disease in a considered territory. This model includes the effect of various control …		 Rama Seck; Diène Ngom; Benjamin Ivorra; Ángel M Ramos; Mathematical biosciences and engineering : MBE 2021-12-16
257 Impact of The Recent Ebola Epidemic with Pandemic Potential on The Economies of Guinea, Liberia and Sierra Leone and Other West African Countries
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Abstract: West Africa experienced its first Ebola epidemic in 2014. Its magnitude in terms of morbidity and mortality was greater than any other epidemic. It has particularly affected …		 Mohamed Lamine Dramé; Paulo Ferrinho; Maria Rosário Oliveira Martins; The Pan African medical journal 2021-12-16
258 Design of Replication-Competent VSV- and Ervebo-Vectored Vaccines Against SARS-CoV-2
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Abstract: Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a global public health emergency. Several vaccine candidates have …		 Qixing Liu; Zhe Ding; Jiaming Lan; Gary Wong; Methods in molecular biology (Clifton, N.J.) 2021-12-16
259 Cryo-EM Analysis of Ebola Virus Nucleocapsid-like Assembly
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Abstract: This protocol describes the reconstitution of the filamentous Ebola virus nucleocapsid-like assembly . This is followed by solving the cryo-EM structure using helical …		 YAN WANG et. al. STAR protocols 2021-12-16
260 InterARTIC: An Interactive Web Application for Whole-genome Nanopore Sequencing Analysis of SARS-CoV-2 and Other Viruses
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Abstract: InterARTIC is an interactive web application for the analysis of viral whole-genome sequencing (WGS) data generated on Oxford Nanopore Technologies (ONT) devices. A graphical …		 JAMES M FERGUSON et. al. Bioinformatics (Oxford, England) 2021-12-15
261 Enhancing The Antiviral Potency of Nucleobases for Potential Broad-Spectrum Antiviral Therapies
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Abstract: Broad-spectrum antiviral therapies hold promise as a first-line defense against emerging viruses by blunting illness severity and spread until vaccines and virus-specific …		 RUBEN SOTO-ACOSTA et. al. Viruses 2021-12-14
262 Developing A Secretory AcGFP1-based IRES Expression System for Efficient Production of Mammalian Recombinant Proteins
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Abstract: To generate stable cell lines that express high levels of recombinant genes often requires screening of a large number of transfected cells using ELISA. The most widely used …		 Zhongcheng Zou; Matthew Spencer; Peter D Sun; Protein expression and purification 2021-12-14
263 A Live-attenuated Viral Vector Vaccine Protects Mice Against Lethal Challenge with Kyasanur Forest Disease Virus
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Abstract: Kyasanur Forest disease virus (KFDV) is a tick-borne flavivirus endemic in India known to cause severe hemorrhagic and encephalitic disease in humans. In recent years, KFDV has …		 BHARTI BHATIA et. al. NPJ vaccines 2021-12-14
264 Identification of Novel Ebola Virus Inhibitors Using Biologically Contained Virus
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Highlight: In this study, we used biologically contained Ebola virus to screen over 4,200 small-molecule drugs and drug-like compounds provided by the Medicines for Malaria Venture (i.e., the Pandemic Response Box and the COVID Box) and the Centre for Drug Design and Discovery (CD3, KU Leuven, Belgium).		 B. VANMECHELEN et. al. bio.microbiology 2021-12-12
265 The 2018-2020 Ebola Outbreak in The Democratic Republic of Congo: A Better Response Had Been Achieved Through Inter-State Coordination in Africa
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Abstract: The Ebola virus disease, formerly known as Ebola hemorrhagic fever, is a severe and often fatal zoonosis in humans. The 2013-2016 West African Ebola outbreak had distinctive …		 RAOUL EMERIC GUETIYA WADOUM et. al. Risk management and healthcare policy 2021-12-10
266 Current State of Ebola Virus Vaccines: A Snapshot
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 Courtney Woolsey; Thomas W Geisbert; PLoS pathogens 2021-12-09
267 Can Major Public Health Emergencies Affect Changes in International Oil Prices?
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Abstract: In order to deepen the understanding of the impact of major public health emergencies on the oil market and to enhance the risk response capability, this study analyzed the …		 An Cheng; Tonghui Chen; Guogang Jiang; Xinru Han; International journal of environmental research and public … 2021-12-08
268 Marburg and Ebola Virus Infections Elicit A Complex, Muted Inflammatory State in Bats
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Highlight: In this study, we outline multiple interconnected pathways that respond to infection by MARV and EBOV, providing insights into the complexity of the mechanisms that enable bats to resist the disease caused by filoviral infections.		 A. D. JAYAPRAKASH et. al. bio.microbiology 2021-12-08
269 Marburg Virus Disease Outbreak Amidst COVID-19 in The Republic of Guinea: A Point of Contention for The Fragile Health System?
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Abstract: In August 2021, the Marburg virus disease (MVD) outbreak was confirmed amid the coronavirus disease 2019 (COVID-19) pandemic in the Republic of Guinea. This is the first time it …		 OSARETIN CHRISTABEL OKONJI et. al. Clinical epidemiology and global health 2021-12-08
270 Ebola Virus Disease Nosocomial Infections in The Democratic Republic of The Congo: A Descriptive Study of Cases During The 2018-2020 Outbreak
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Abstract: To describe the characteristics of nosocomial cases of Ebola virus disease (EVD) in the Democratic Republic of the Congo between July 2018 and May 2020 in order to inform future …		 APRIL BALLER et. al. International journal of infectious diseases : IJID : … 2021-12-07
271 Economic Evaluation Using Dynamic Transition Modeling of Ebola Virus Vaccination in Lower-and-middle-income Countries
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Abstract: With the increasing occurrence of infectious diseases in lower-and-middle-income countries (LMICs), emergency preparedness is essential for rapid response and mitigation. Economic …		 Mavis Obeng-Kusi; Magdiel A Habila; Denise J Roe; Brian Erstad; Ivo Abraham; Journal of medical economics 2021-12-06
272 Improving Sepsis Care in Africa: An Opportunity for Change?
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Abstract: Sepsis is common and represents a major public health burden with significant associated morbidity and mortality. However, despite substantial advances in sepsis recognition and …		 Alexander James Keeley; Emmanuel Nsutebu; The Pan African medical journal 2021-12-06
273 Rhesus Macaque CODEX Multiplexed Immunohistochemistry Panel for Studying Immune Responses During Ebola Infection
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Abstract: Non-human primate (NHP) animal models are an integral part of the drug research and development process. For some biothreat pathogens, animal model challenge studies may offer the …		 SIZUN JIANG et. al. Frontiers in immunology 2021-12-06
274 A Review of Infectious Diseases Associated with Religious and Nonreligious Rituals
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Abstract: Rituals are an integral part of human life but a wide range of rituals (both religious and non-religious), from self-flagellation to blood brotherhood to ritual sprinkling of holy …		 Kiran Gajurel; Stan Deresinski; Interdisciplinary perspectives on infectious diseases 2021-12-06
275 Transcriptomic Signatures Induced By The Ebola Virus Vaccine RVSVΔG-ZEBOV-GP in Adult Cohorts in Europe, Africa, and North America: A Molecular Biomarker Study
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Abstract: A recombinant vesicular stomatitis virus vector expressing the Zaire Ebola virus glycoprotein (rVSVΔG-ZEBOV-GP) vaccine has been reported as safe, immunogenic, and highly …		 ELEONORA VIANELLO et. al. The Lancet. Microbe 2021-12-06
276 Quantification of Type I Interferon Inhibition By Viral Proteins: Ebola Virus As A Case Study
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Abstract: Type I interferons (IFNs) are cytokines with both antiviral properties and protective roles in innate immune responses to viral infection. They induce an antiviral cellular state …		 MACAULEY LOCKE et. al. Viruses 2021-12-04
277 Rapid Establishment of A Frontline Field Laboratory in Response to An Imported Outbreak of Ebola Virus Disease in Western Uganda, June 2019
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Abstract: The Democratic Republic of the Congo (DRC) declared an Ebola virus disease (EVD) outbreak in North Kivu in August 2018. By June 2019, the outbreak had spread to 26 health zones in …		 AMY J SCHUH et. al. PLoS neglected tropical diseases 2021-12-03
278 Editorial Overview: An Initiative Toward Ebolavirus Disease (EVD) Free World: An Edited Special Anti-infective Issue on Ebola Virus Disease
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 Elijah I Ohimain; Chiranjib Chakraborty; Current opinion in pharmacology 2021-12-02
279 A Reliable Solution of Nonlinear Time Dependent Fractional Model of Ebola Virus Disease with Arbitrary Order Derivative in Liouville-Caputo Sense
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Abstract: In this article, the analysis of an arbitrary order Ebola virus disease model is conducted to find out its reliable solution. The fractional derivative is taken in …		 Vinod Kumar Bhardwaj; Manish Goyal; International journal of applied and computational … 2021-11-30
280 Computational Study on Potential Novel Anti-Ebola Virus Protein VP35 Natural Compounds
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Abstract: Ebola virus (EBOV) is one of the most lethal pathogens that can infect humans. The Ebola viral protein VP35 (EBOV VP35) inhibits host IFN-α/β production by interfering with host …		 LOUIS K S DARKO et. al. Biomedicines 2021-11-30
281 Pacing Forward in The Face of Fragility: Lessons From African Institutions and Governments’ Response to Public Health Emergencies
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Abstract: Africa is home to 54 United Nation member states, each possessing a wealth of ethno-cultural, physiographic, and economic diversity. While Africa is credited as having the …		 Byron Bitanihirwe; Derrick Ssewanyana; Ismael Ddumba-Nyanzi; Frontiers in public health 2021-11-25
282 The Power of Music to Prevent and Control Emerging Infectious Diseases
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Abstract: Music is a powerful approach to engage communities and disseminate information. Specifically, health campaigns employing music have been used to promote behaviors that can prevent …		 JULIO A BENAVIDES et. al. Frontiers in medicine 2021-11-25
283 Broad-Spectrum In Vitro Antiviral Activity of ODBG-P-RVn: An Orally-Available, Lipid-Modified Monophosphate Prodrug of Remdesivir Parent Nucleoside (GS-441524)
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Abstract: The necessity for intravenous administration of remdesivir confines its utility for treatment of coronavirus disease 2019 (COVID-19) to hospitalized patients. We evaluated the …		 MICHAEL K LO et. al. Microbiology spectrum 2021-11-24
284 The Ebola Crisis and People with Disabilities’ Access to Healthcare and Government Services in Liberia
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Abstract: There has been little research on the impact of the 2014-2015 West African Ebola crisis on people with disabilities. This paper outlines the way in which the Ebola Virus Disease …		 MARIA KETT et. al. International journal for equity in health 2021-11-24
285 [New Analogues of Uridine As Possible Anti-Viral Agents Specific to SARS-CoV-2]
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Abstract: The development of specific drugs against SARS-CoV-2 infection is a major challenge facing global science and healthcare. Despite numerous attempts, there are still no truly …		 A A MASLOVA et. al. Molekuliarnaia biologiia 2021-11-24
286 Data Science Approaches to Infectious Disease Surveillance
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Abstract: Novel data science approaches are needed to confront large-scale infectious disease epidemics such as COVID-19, human immunodeficiency viruses, African swine flu and Ebola. Human …		 Qingpeng Zhang; Philosophical transactions. Series A, Mathematical, … 2021-11-22
287 Novel Use of Capture-Recapture Methods to Estimate Completeness of Contact Tracing During An Ebola Outbreak, Democratic Republic of The Congo, 2018-2020
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Abstract: Despite its critical role in containing outbreaks, the efficacy of contact tracing, measured as the sensitivity of case detection, remains an elusive metric. We estimated the …		 JONATHAN A POLONSKY et. al. Emerging infectious diseases 2021-11-22
288 Evaluation of Early Warning, Alert and Response System for Ebola Virus Disease, Democratic Republic of The Congo, 2018-2020
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Abstract: The 10th and largest Ebola virus disease epidemic in the Democratic Republic of the Congo (DRC) was declared in North Kivu Province in August 2018 and ended in June 2020. We …		 MORY KEITA et. al. Emerging infectious diseases 2021-11-22
289 Andrographolide: A Herbal-Chemosynthetic Approach for Enhancing Immunity, Combating Viral Infections, and Its Implication on Human Health
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Abstract: Plants consistently synthesize and accumulate medically valuable secondary metabolites which can be isolated and clinically tested under in vitro conditions. An advancement with …		 Archana Mishra; Haq Abdul Shaik; Rakesh Kumar Sinha; Bakht Ramin Shah; Molecules (Basel, Switzerland) 2021-11-21
290 Cross-Reactive Antibodies to SARS-CoV-2 and MERS-CoV in Pre-COVID-19 Blood Samples from Sierra Leoneans
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Abstract: Many countries in sub-Saharan Africa have experienced lower COVID-19 caseloads and fewer deaths than countries in other regions worldwide. Under-reporting of cases and a younger …		 RODRIGO BORREGA et. al. Viruses 2021-11-21
291 Gender-based Violence and Infectious Disease in Humanitarian Settings: Lessons Learned from Ebola, Zika, and COVID-19 to Inform Syndemic Policy Making
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Abstract: The impacts of infectious disease outbreaks, epidemics, and pandemics are not gender neutral. Instead, infectious diseases and gender-based violence (GBV) mutually reinforce each …		 MELISSA MEINHART et. al. Conflict and health 2021-11-20
292 Functional Importance of Hydrophobic Patches on The Ebola Virus VP35 IFN-Inhibitory Domain
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Abstract: Viral protein 35 (VP35) of Ebola virus (EBOV) is a multifunctional protein that mainly acts as a viral polymerase cofactor and an interferon antagonist. VP35 interacts with the …		 NODOKA KASAJIMA et. al. Viruses 2021-11-20
293 A Virus-specific Monocyte Inflammatory Phenotype Is Induced By SARS-CoV-2 at The Immune-epithelial Interface
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Abstract: Infection by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) provokes a potentially fatal pneumonia with multiorgan failure, and high systemic inflammation. To gain …		 JULIETTE LEON et. al. Proceedings of the National Academy of Sciences of the … 2021-11-19
294 Prevention of Emerging Infections in Children
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Abstract: Prevention of emerging infections in children is a dynamic arena where substantial medical advances have enabled intervention and prevention of infection outbreaks. This article …		 Thanyawee Puthanakit; Suvaporn Anugulruengkitt; Watsamon Jantarabenjakul; Pediatric clinics of North America 2021-11-19
295 Implications of Glycosaminoglycans on Viral Zoonotic Diseases
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Abstract: Zoonotic diseases are infectious diseases that pass from animals to humans. These include diseases caused by viruses, bacteria, fungi, and parasites and can be transmitted through …		 Sarah Bauer; Fuming Zhang; Robert J Linhardt; Diseases (Basel, Switzerland) 2021-11-17
296 Natural History of Aerosol-Induced Ebola Virus Disease in Rhesus Macaques
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Abstract: Ebola virus disease (EVD) is a serious global health concern because case fatality rates are approximately 50% due to recent widespread outbreaks in Africa. Well-defined nonhuman …		 ISAAC DOWNS et. al. Viruses 2021-11-17
297 Increasing Ebola Transmission Behaviors 6 months Post-vaccination: Comparing Vaccinated and Unvaccinated Populations Near 2018 Mbandaka Ebola Outbreak in The Democratic Republic of Congo
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Abstract: In 2018, the Democratic Republic of the Congo (DRC) declared its 9th and 10th Zaire ebolavirus (EBOV) outbreaks, in the Equateur province (end: July 2018), and in the eastern …		 NICOLE A HOFF et. al. Vaccine 2021-11-16
298 The Network Epidemiology of An Ebola Epidemic
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Highlight: Here, we revisit one of the largest public health efforts deployed against a localized epidemic: the 2014-2016 Ebola Virus Disease (EVD) epidemic in Sierra Leone.		 LAURENT HÉBERT-DUFRESNE et. al. arxiv-q-bio.PE 2021-11-16
299 Registered Nurses’ Perceptions After A Patient with Ebola Virus Disease Is Admitted to Their Hospital
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Abstract: Emerging diseases affect the nursing workforce, but little is known about the willingness of registered nurses (RNs) to work during outbreaks (eg, Ebola virus disease, COVID-19). …		 Nanci Nagel; Helen Salisbury; Holly Hinson; Health security 2021-11-15
300 A Cryptic Pocket in Ebola VP35 Allosterically Controls RNA Binding
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Highlight: Here, we apply a general pipeline for identifying cryptic pockets to the interferon inhibitory domain (IID) of Ebola viral protein 35 (VP35).		 M. A. CRUZ et. al. bio.biochemistry 2021-11-15
301 Adenovirus Vector-based Vaccine for Infectious Diseases
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Abstract: Replication-incompetent adenovirus (Ad) vectors have been widely used as gene delivery vehicles in both gene therapy studies and basic studies for gene function analysis due to …		 Fuminori Sakurai; Masashi Tachibana; Hiroyuki Mizuguchi; Drug metabolism and pharmacokinetics 2021-11-12
302 Fear, Distress, and Perceived Risk Shape Stigma Toward Ebola Survivors: A Prospective Longitudinal Study
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Abstract: During the 2014-15 Ebola Virus Disease (EVD) epidemic, thousands of people in Sierra Leone were infected with the devastating virus and survived. Years after the epidemic was …		 CARA M ANTONACCIO et. al. BMC public health 2021-11-11
303 Evolutionary and Antigenic Profiling of The Tendentious D614G Mutation of SARS-CoV-2 in Gujarat, India
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Abstract: Humankind has suffered many pandemics in history including measles, SARS, MERS, Ebola, and recently the novel Coronavirus disease caused by SARS-CoV-2. As of September 2021, it …		 JAY NIMAVAT et. al. Frontiers in genetics 2021-11-11
304 Structure and Function of Negative-strand RNA Virus Polymerase Complexes
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Abstract: Viruses with negative-strand RNA genomes (NSVs) include many highly pathogenic and economically devastating disease-causing agents of humans, livestock, and plants-highlighted by …		 Jesse D Pyle; Sean P J Whelan; Louis-Marie Bloyet; The Enzymes 2021-11-10
305 Cellular and Humoral Immunity to Ebola Zaire Glycoprotein and Viral Vector Proteins Following Immunization with Recombinant Vesicular Stomatitis Virus-Based Ebola Vaccine (rVSV{triangleup}G-EBOV-GP)
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Abstract: While effective at preventing Zaire ebolavirus (EBOV) disease, cellular immunity to EBOV and vector-directed immunity elicited by the recombinant vesicular stomatitis virus …		 V. N. RAABE et. al. med.infectious-diseases 2021-11-10
306 Nanotechnology Applications of Flavonoids for Viral Diseases
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Abstract: Recent years have witnessed the emergence of several viral diseases, including various zoonotic diseases such as the current pandemic caused by the Severe Acute Respiratory …		 KHOSHNUR JANNAT et. al. Pharmaceutics 2021-11-08
307 Species-specific Quantification of Circulating Ebolavirus Burden Using VP40-derived Peptide Variants
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Abstract: Six ebolavirus species are reported to date, including human pathogens Bundibugyo virus (BDBV), Ebola virus (EBOV), Sudan virus (SUDV), and Taï Forest virus (TAFV); non-human …		 QINGBO SHU et. al. PLoS pathogens 2021-11-08
308 Deep Time Structural Evolution of Retroviral and Filoviral Surface Envelope Proteins
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Abstract: The retroviral surface envelope protein subunit (SU) mediates receptor binding and triggers membrane fusion by the transmembrane subunit (TM). SU evolves rapidly under strong …		 I. Hotzel; bio.microbiology 2021-11-05
309 Malaria and COVID-19: A Double Battle for Burundi
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Abstract: Malaria has become a serious public health concern in Burundi. An outbreak that has the potential to evolve into an epidemic has eradicated nearly as many individuals as the Ebola …		 PARVATHY MOHANAN et. al. African journal of emergency medicine : Revue africaine de … 2021-11-05
310 Therapeutic Vaccination Strategies Against EBOV By RVSV-EBOV-GP: The Role of Innate Immunity
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Abstract: Zaire Ebola virus (EBOV) is a member of the Filoviridae family. Infection with EBOV causes Ebola virus disease (EVD) characterized by excessive inflammation, lymphocyte death, …		 Amanda N Pinski; Ilhem Messaoudi; Current opinion in virology 2021-11-05
311 A Qualitative Study of COVID-19 Related Reasons for Delayed Presentation of Patients with Chest Pain During The COVID-19 Pandemic
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Abstract: In previous pandemics such as the Ebola virus outbreak in West Africa, it has been observed that patients with non-pandemic related complaints, delay their presentation to …		 Hanlie Dreyer; Katya De Oliveira; Vidya Lalloo; Andreas Engelbrecht; African journal of emergency medicine : Revue africaine de … 2021-11-05
312 Comparison of Viral RNA-host Protein Interactomes Across Pathogenic RNA Viruses Informs Rapid Antiviral Drug Discovery for SARS-CoV-2
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Abstract: In contrast to the extensive research about viral protein-host protein interactions that has revealed major insights about how RNA viruses engage with host cells during infection, …		 SHAOJUN ZHANG et. al. Cell research 2021-11-04
313 What Effect Might Border Screening Have on Preventing The Importation of COVID-19 Compared with Other Infections? A Modelling Study
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Abstract: The effectiveness of screening travellers during times of international disease outbreak is contentious, especially as the reduction in the risk of disease importation can be very …		 Declan Bays; Emma Bennett; Thomas Finnie; Epidemiology and infection 2021-11-04
314 Sector-by-sector Analysis of Dependence Dynamics Between Global Large-cap Companies and Infectious Diseases: A Time-varying Copula Approach in EBOV and COVID-19 Episodes
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Abstract: Infectious diseases and widespread outbreaks influence different sectors of the economy, including the stock market. In this article, we investigate the effect of EBOV and …		 Mahdi Ghaemi Asl; Hamid Reza Tavakkoli; Muhammad Mahdi Rashidi; PloS one 2021-11-03
315 Establishing Healthcare Worker Performance and Safety in Providing Critical Care for Patients in A Simulated Ebola Treatment Unit: Non-Randomized Pilot Study
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Abstract: Improving the provision of supportive care for patients with Ebola is an important quality improvement initiative. We designed a simulated Ebola Treatment Unit (ETU) to assess …		 PETER KIIZA et. al. Viruses 2021-11-02
316 Glycopeptide Antibiotic Teicoplanin Inhibits Cell Entry of SARS-CoV-2 By Suppressing The Proteolytic Activity of Cathepsin L
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Highlight: Here, we found that the cleavage sites of CTSL on the Spike of SARS-CoV-2 were highly conserved among all the variants.		 F. YU et. al. bio.microbiology 2021-11-01
317 Post-Ebola Sequelae Among Ebola Child Survivors in Sierra Leone
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Abstract: There are limited data regarding the long-term health effects of child survivors of the 2013-2016 West African Ebola virus disease (EVD) outbreak. Here, we assess post-Ebola …		 Claudette Amuzu; Peter Bai James; Abdulai Jawo Bah; Alex Vandy Saffa Bayoh; Shepherd Roee Singer; BMC pediatrics 2021-10-30
318 Human Parainfluenza Virus 3 Phosphoprotein Is A Tetramer and Shares Structural and Interaction Features with Ebola Phosphoprotein VP35
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Abstract: The human parainfluenza virus 3 (HPIV3) poses a risk for pneumonia development in young children and immunocompromised patients. To investigate mechanisms of HPIV3 pathogenesis, …		 JOAQUIN RODRIGUEZ GALVAN et. al. Biomolecules 2021-10-29
319 Safety and Immunogenicity of 2-dose Heterologous Ad26.ZEBOV, MVA-BN-Filo Ebola Vaccination in Healthy and HIV-infected Adults: A Randomised, Placebo-controlled Phase II Clinical Trial in Africa
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Abstract: We investigated safety, tolerability, and immunogenicity of the heterologous 2-dose Ebola vaccination regimen in healthy and HIV-infected adults with different intervals between …		 HOURERATOU BARRY et. al. PLoS medicine 2021-10-29
320 Tolerance and Persistence of Ebola Virus in Primary Cells from Mops Condylurus , A Potential Ebola Virus Reservoir
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Abstract: Although there have been documented Ebola virus disease outbreaks for more than 40 years, the natural reservoir host has not been identified. Recent studies provide evidence that …		 MARCEL BOKELMANN et. al. Viruses 2021-10-29
321 Identification and Characterization of Short Leader and Trailer RNAs Synthesized By The Ebola Virus RNA Polymerase
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Abstract: Transcription of non-segmented negative sense (NNS) RNA viruses follows a stop-start mechanism and is thought to be initiated at the genome’s very 3′-end. The synthesis of short …		 SIMONE BACH et. al. PLoS pathogens 2021-10-26
322 Modulating Neurological Complications of Emerging Infectious Diseases: Mechanistic Approaches to Candidate Phytochemicals
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Abstract: Growing studies are revealing the critical manifestations of influenza, dengue virus (DENV) infection, Zika virus (ZIKV) disease, and Ebola virus disease (EVD) as emerging …		 Sajad Fakhri; Pardis Mohammadi Pour; Sana Piri; Mohammad Hosein Farzaei; Javier Echeverría; Frontiers in pharmacology 2021-10-26
323 Gut Microbiota of Bats: Pro-mutagenic Properties and Possible Frontiers in Preventing Emerging Disease
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Abstract: Bats are potential natural reservoirs for emerging viruses, causing deadly human diseases, such as COVID-19, MERS, SARS, Nipah, Hendra, and Ebola infections. The fundamental …		 IGOR V POPOV et. al. Scientific reports 2021-10-26
324 Scalable Bayesian Divergence Time Estimation with Ratio Transformations
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Highlight: To overcome this limitation, we explore a ratio transformation that maps the original N – 1 internal node heights into a space of one height parameter and N – 2 ratio parameters.		 XIANG JI et. al. arxiv-q-bio.PE 2021-10-25
325 Characterization of The Therapeutic Effect of Antibodies Targeting The Ebola Glycoprotein Using A Novel BSL2-compliant RVSVΔG-EBOV-GP Infection Model
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Abstract: Ebola virus (EBOV) infections cause haemorrhagic fever, multi-organ failure and death, and survivors can experience neurological sequelae. Licensing of monoclonal antibodies …		 HA-NA LEE et. al. Emerging microbes & infections 2021-10-22
326 Ebola Viral Receptor Niemann-Pick C1 (NPC1) in Human Cancers: A Potential Biomarker and Immunotherapeutic Target
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 Zhen Fang; Peijuan Li; Liang Shang; Fei Li; Human cell 2021-10-22
327 The Deployment of Mobile Diagnostic Laboratories for Ebola Virus Disease Diagnostics in Sierra Leone and Guinea
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Abstract: Ebola virus emerged in West Africa in December 2013. The ease of mobility, porous borders, and lack of public health infrastructure led to the largest Ebola virus disease (EVD) …		 LANCE D PRESSER et. al. African journal of laboratory medicine 2021-10-22
328 The Private Versus Public Contribution to The Biomedical Literature During The COVID-19, Ebola, H1N1, and Zika Public Health Emergencies
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Abstract: The private versus public contribution to developing new health knowledge and interventions is deeply contentious. Proponents of commercial innovation highlight its role in …		 Reed F Beall; Javad Moradpour; Aidan Hollis; PloS one 2021-10-22
329 Cross-sectional Survey of Knowledge and Attitudes of Healthcare Workers and Community Members Toward The Ebola Virus Disease and Antimicrobial Resistance Pathogens Outbreaks in Nigeria
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Abstract: the 2014 Ebola virus disease (EVD) outbreak in Nigeria has further raised the awareness of health-care workers (HCWs) and community members (MCs) on the threat posed by infectious …		 IBRAHIM YUSUF et. al. The Pan African medical journal 2021-10-22
330 Risk Analysis By Failure Modes, Effects and Criticality Analysis and Biosafety Management During Collective Air Medical Evacuation of Critically Ill Coronavirus Disease 2019 Patients
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Abstract: In March 2020, coronavirus disease 2019 (COVID-19) caused an overwhelming pandemic. To relieve overloaded intensive care units in the most affected regions, the French Ministry of …		 LIONEL KOCH et. al. Air medical journal 2021-10-21
331 Community Health Workers’ Job Satisfaction in Ebola-stricken Areas of Sierra Leone and Its Implication for COVID-19 Containment: A Cross-sectional Mixed-methods Study
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Abstract: Community health workers (CHWs) played important roles in supplementing scarce healthcare workforce in Sierra Leone during the Ebola outbreak, causing the government to launch the …		 OSMAN KOROMA et. al. BMJ open 2021-10-20
332 Operational Considerations in Global Health Modeling
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Abstract: Epidemiological modeling and simulation can contribute cooperatively across multifaceted areas of biosurveillance systems. These efforts can be used to support real-time …		 KATHERINE M BROADWAY et. al. Pathogens (Basel, Switzerland) 2021-10-19
333 How Antibodies Recognize Pathogenic Viruses: Structural Correlates of Antibody Neutralization of HIV-1, SARS-CoV-2, and Zika
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Abstract: The H1N1 pandemic of 2009-2010, MERS epidemic of 2012, Ebola epidemics of 2013-2016 and 2018-2020, Zika epidemic of 2015-2016, and COVID-19 pandemic of 2019-2021, are recent …		 Morgan E Abernathy; Kim-Marie A Dam; Shannon R Esswein; Claudia A Jette; Pamela J Bjorkman; Viruses 2021-10-19
334 Analysis of The Management of The Tenth Ebola Virus Disease Outbreak in The Democratic Republic of Congo: Developing A Multidisciplinary Response Model to Strengthen The Healthcare System During Disease Outbreaks
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Abstract: The declaration of any public health emergency in the Democratic Republic of Congo (DRC) is usually followed by the provision of technical and organizational support from …		 BIVES MUTUME VIVALYA et. al. Globalization and health 2021-10-18
335 Mechanisms of Immune Evasion By Ebola Virus
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Abstract: The 2013-2016 Ebola virus epidemic in West Africa, which also spread to the USA, UK and Europe, was the largest reported outbreak till date (World Health Organization. 2016. …		 Suchita Bhattacharyya; Advances in experimental medicine and biology 2021-10-18
336 Structural and Functional Aspects of Ebola Virus Proteins
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Abstract: Ebola virus (EBOV), member of genus , family , have a non-segmented, single-stranded RNA that contains seven genes: (a) nucleoprotein (NP), (b) viral protein 35 (VP35), (c) VP40, …		 Sahil Jain; Ekaterina Martynova; Albert Rizvanov; Svetlana Khaiboullina; Manoj Baranwal; Pathogens (Basel, Switzerland) 2021-10-15
337 Bioterrorism
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Abstract: Bioterrorism is the deliberate release of viruses, bacteria, toxins, or fungi with the goal of causing panic, mass casualties, or severe economic disruption. From 1981 to 2018, …		 Nicholas A Rathjen; S David Shahbodaghi; American family physician 2021-10-15
338 Self-Replicating RNA Viruses for Vaccine Development Against Infectious Diseases and Cancer
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Abstract: Alphaviruses, flaviviruses, measles viruses and rhabdoviruses are enveloped single-stranded RNA viruses, which have been engineered for recombinant protein expression and vaccine …		 Kenneth Lundstrom; Vaccines 2021-10-15
339 ONTdeCIPHER: An Amplicon-based Nanopore Sequencing Pipeline for Tracking Pathogen Variants
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Highlight: Results: Here, we present ONTdeCIPHER, an amplicon-based Oxford Nanopore Technology (ONT) sequencing pipeline to analyze the genetic diversity of SARS-CoV-2 and other pathogenes.		 E. CHERIF et. al. bio.bioinformatics 2021-10-14
340 Accessing Unproven Interventions in The COVID-19 Pandemic: Discussion on The Ethics of ‘compassionate Therapies’ in Times of Catastrophic Pandemics
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Abstract: Since the onset of the SARS-CoV-2 pandemic, an array of off-label interventions has been used to treat patients, either provided as compassionate care or tested in clinical …		 Shlomit Zuckerman; Yaron Barlavie; Yaron Niv; Dana Arad; Shaul Lev; Journal of medical ethics 2021-10-13
341 Infectious Disease in An Era of Global Change
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Abstract: The twenty-first century has witnessed a wave of severe infectious disease outbreaks, not least the COVID-19 pandemic, which has had a devastating impact on lives and livelihoods …		 RACHEL E BAKER et. al. Nature reviews. Microbiology 2021-10-13
342 Preparing for Disease X
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Abstract: The past 30 years have exposed the global public health and economic threats posed by the emergence of infectious pathogens with epidemic and pandemic potential. Severe acute …		 Maria D Van Kerkhove; Michael J Ryan; Tedros Adhanom Ghebreyesus; Science (New York, N.Y.) 2021-10-13
343 Control and Anticontrol of Chaos in Fractional-order Models of Diabetes, HIV, Dengue, Migraine, Parkinson’s and Ebola Virus Diseases
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Abstract: This work proposes new fractional-order (FO) models of six chaotic diseases whose fractional dynamics have not been studied so far in literature. Secondly, design and analysis of …		 Manashita Borah; Debanita Das; Antara Gayan; Flavio Fenton; Elizabeth Cherry; Chaos, solitons, and fractals 2021-10-12
344 Identification and Characterization of A Novel Single Domain Antibody Against Ebola Virus
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Abstract: Ebola virus (EBOV) belongs to the Filoviridae family and causes severe illnesses such as hemorrhagic fever with a high mortality rate up to 90%. Now two antibody drugs termed …		 RUI WANG et. al. Virologica Sinica 2021-10-11
345 The Genetic Impact of An Ebola Outbreak on A Wild Gorilla Population
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Abstract: Numerous Ebola virus outbreaks have occurred in Equatorial Africa over the past decades. Besides human fatalities, gorillas and chimpanzees have also succumbed to the fatal virus. …		 CLAUDIA FONTSERE et. al. BMC genomics 2021-10-11
346 Role of Key Infectivity Parameters in The Transmission of Ebola Virus Makona in Macaques
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Abstract: Many characteristics associated with Ebola virus disease remain to be fully understood. It is known that direct contact with infected bodily fluids is an associated risk factor, …		 MARC-ANTOINE DE LA VEGA et. al. The Journal of infectious diseases 2021-10-09
347 HRSA’s PEPFAR-Supported Resilient and Responsive Health Systems Initiative in Liberia
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Abstract: During the 2014-16 Ebola outbreak, Liberia suffered 2,544 deaths, including 8% of its doctors, nurses and midwives. The Government responded in 2016 with a seven-year Health …		 George Tidwell; Myat Htoo Razak; Annals of global health 2021-10-08
348 Liberia’s First Health Workforce Program Strategy: Reflections and Lessons Learned
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Abstract: Following civil war and the Ebola epidemic, Liberia’s health workforce was devastated, essential health services and primary care were disrupted, and health outcomes for maternal …		 BERNICE DAHN et. al. Annals of global health 2021-10-08
349 Health Management Workforce Capacity-Building in Liberia, Post-Ebola
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Abstract: Following the Ebola crisis in Liberia in 2014-15, the Liberian Ministry of Health developed a strategy to build a fit-for-purpose health workforce, focusing on both health care …		 KRISTINA TALBERT-SLAGLE et. al. Annals of global health 2021-10-08
350 Facing COVID-19 in Liberia: Adaptations of The Resilient and Responsive Health Systems Initiative
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Abstract: The 5-year Resilient and Responsive Health Systems (RRHS)-Liberia Initiative, funded by PEPFAR via HRSA, launched in 2017 and was designed to support the implementation of …		 REGAN H MARSH et. al. Annals of global health 2021-10-08
351 Development and Characterization of Influenza M2 Ectodomain And/or HA Stalk-based DC-targeting Vaccines for Different Influenza Infections
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Highlight: Here, we revealed the efficacy of novel influenza vaccine candidates based on Ebola glycoprotein (EboGP) DC-targeting domain (E{Delta}M) fusion protein technology.		 X. YAO et. al. bio.microbiology 2021-10-07
352 The Epidemic Failure Cycle Hypothesis: Towards Understanding The Global Community’s Recent Failures in Responding to An Epidemic
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Abstract: Within a few years, the global community has failed twice in responding to large viral infection outbreaks: the Ebola epidemic in 2014 and the SARS-Cov-2 pandemic in 2020. There …		 Dirk Richter; Simeon Zuercher; Journal of infection and public health 2021-10-06
353 Expanded Histopathology and Tropism of Ebola Virus in The Rhesus Macaque Model: Potential for Sexual Transmission, Altered Adrenomedullary Hormone Production, and Early Viral Replication in Liver
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Abstract: The pathogenesis of Ebola virus disease (EVD) is still incomplete, in spite of the availability of a nonhuman primate modelfor more than 4 decades. To further investigate EVD …		 DAVID X LIU et. al. The American journal of pathology 2021-10-06
354 On-Demand Patient-Specific Phenotype-to-Genotype Ebola Virus Characterization
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Abstract: Biosafety, biosecurity, logistical, political, and technical considerations can delay or prevent the wide dissemination of source material containing viable virus from the …		 BRETT F BEITZEL et. al. Viruses 2021-10-06
355 Establishment of Intestinal Organoid from Rousettus Leschenaultii and The Susceptibility to Bat-Associated Viruses, SARS-CoV-2 and Pteropine Orthoreovirus
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Abstract: Various pathogens, such as Ebola virus, Marburg virus, Nipah virus, Hendra virus, Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV), Middle East Respiratory Syndrome …		 MOHAMED ELBADAWY et. al. International journal of molecular sciences 2021-10-05
356 The Role of Animal Research in Pandemic Responses
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Abstract: The significant advances made by the global scientific community during the COVID-19 pandemic, exemplified by the development of multiple SARS-CoV-2 vaccines in less than 1 y, …		 Jacqueline K Brockhurst; Jason S Villano; Comparative medicine 2021-10-05
357 COVID-19 Vaccines: Adenoviral Vectors
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Abstract: The worldwide pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to the unprecedented pace of …		 Catherine Jacob-Dolan; Dan H Barouch; Annual review of medicine 2021-10-05
358 A Magneto-optical Biochip for Rapid Assay Based on The Cotton-Mouton Effect of Γ-Fe 2 O 3 @Au Core/shell Nanoparticles
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Abstract: In the past decades, different diseases and viruses, such as Ebola, MERS and COVID-19, impacted the human society and caused huge cost in different fields. With the increasing …		 Kuen-Lin Chen; Zih-Yan Yang; Chin-Wei Lin; Journal of nanobiotechnology 2021-10-01
359 Immunocompromised Cas9 Transgenic Mice for Rapid In vivo Assessment of Host Factors Involved in Highly Pathogenic Virus Infection
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Abstract: Targeting host factors for anti-viral development offers several potential advantages over traditional countermeasures that include broad-spectrum activity and prevention of …		 NICOLE COLLETTE et. al. Molecular therapy. Methods & clinical development 2021-10-01
360 Coronavirus Disease 2019 on The Heels of Ebola Virus Disease in West Africa
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Abstract: This study utilized modeling and simulation to examine the effectiveness of current and potential future COVID-19 response interventions in the West African countries of Guinea, …		 ZYGMUNT F DEMBEK et. al. Pathogens (Basel, Switzerland) 2021-10-01
361 Estimation of Ebola’s Spillover Infection Exposure in Sierra Leone Based on Sociodemographic and Economic Factors
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Highlight: To that end, we designed and conducted a survey in Sierra Leone and implement a pipeline to analyze data using regression and machine learning techniques.		 SENA MURSEL et. al. arxiv-q-bio.PE 2021-09-30
362 Pyronaridine Protects Against SARS-CoV-2 in Mouse
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Highlight: We used this as justification to evaluate three molecules we had previously identified computationally with antiviral activity against Ebola and Marburg.		 A. C. PUHL et. al. bio.pharmacology-and-toxicology 2021-09-30
363 Heterologous Prime-boost Regimens with HAdV-5 and NDV Vectors Elicit Stronger Immune Responses to Ebola Virus Than Homologous Regimens in Mice
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Abstract: The 2014 Ebola outbreak in West Africa resulted in more than 11,000 deaths, highlighting the need for a vaccine. A phase I clinical trial of a human adenovirus type 5 vector-based …		 WEI ZHAO et. al. Archives of virology 2021-09-30
364 Remdesivir Is Efficacious in Rhesus Monkeys Exposed to Aerosolized Ebola Virus
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Abstract: Efficacious therapeutics for Ebola virus disease are in great demand. Ebola virus infections mediated by mucosal exposure, and aerosolization in particular, present a novel …		 TRAVIS K WARREN et. al. Scientific reports 2021-09-30
365 Reovirus Infection Is Regulated By NPC1 and Endosomal Cholesterol Homeostasis
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Highlight: We identified NPC1 in CRISPR and RNA interference screens as a putative host factor for infection by mammalian orthoreovirus (reovirus).		 P. ORTEGA GONZALEZ et. al. bio.cell-biology 2021-09-30
366 Synthetic Nanobody-Functionalized Nanoparticles for Accelerated Development of Rapid, Accessible Detection of Viral Antigens
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Highlight: Here we present a generalizable assay platform, nanobody-functionalized nanoparticles for rapid, electronic detection (Nano2RED), demonstrated in the detection of Ebola and COVID-19 antigens.		 X. CHEN et. al. bio.bioengineering 2021-09-30
367 Qualitative Review of Organizational Responses to Rumors in The 2014-2016 Ebola Virus Disease Outbreak in Liberia and Sierra Leone
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Abstract: Rumors and misperceptions were a persistent challenge in the response to the 2014-2016 Ebola Virus Disease (EVD) outbreak in West Africa. This study aimed to document …		 Amelia J Brandt; Bonnie Katalenich; David W Seal; Global health, science and practice 2021-09-30
368 A Virus-specific Monocyte Inflammatory Phenotype Is Induced By SARS-CoV2 at The Immune-epithelial Interface
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Highlight: To gain mechanistic insight and ferret out the root of this immune dysregulation, we modeled by in vitro co-culture the interactions between infected epithelial cells and immunocytes.		 J. LEON et. al. bio.immunology 2021-09-29
369 The Manifold Roles of Sphingolipids in Viral Infections
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Abstract: Sphingolipids are essential components of eukaryotic cells. In this review, we want to exemplarily illustrate what is known about the interactions of sphingolipids with various …		 ELITA AVOTA et. al. Frontiers in physiology 2021-09-29
370 Zoonotic Potential of A Novel Bat Morbillivirus
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Abstract: Bats are significant reservoir hosts for many viruses with zoonotic potential1. SARS-CoV-2, Ebola virus, and Nipah virus are examples of such viruses that have caused deadly …		 BENHUR LEE et. al. Research square 2021-09-29
371 Versatile and Rapid Microfluidics-assisted Antibody Discovery
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Abstract: Recent years have seen unparalleled development of microfluidic applications for antibody discovery in both academic and pharmaceutical research. Microfluidics can support native …		 RAMONA GAA et. al. mAbs 2021-09-29
372 Dose-Dependent Response to Infection with Ebola Virus in The Ferret Model and Evidence of Viral Evolution in The Eye
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Abstract: Filoviruses cause high-consequence infections with limited approved medical countermeasures (MCMs). MCM development is dependent upon well-characterized animal models for the …		 ROBERT J WATSON et. al. Journal of virology 2021-09-29
373 DR Congo: WHO Staff Abused Women and Girls in Ebola Outbreak, Says harrowing Independent Report
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 Jacqui Wise; BMJ (Clinical research ed.) 2021-09-29
374 Ethanol Inactivation of Enveloped Viruses: Structural and Surface Chemistry Insights Into Phi6
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Abstract: Lipid-enveloped viruses, such as Ebola, influenza, or coronaviruses, are a major threat to human health. Ethanol is an efficient disinfectant that is widely used to inactivate …		 Samuel Watts; Madeleine Ramstedt; Stefan Salentinig; The journal of physical chemistry letters 2021-09-28
375 Open-label, Randomised, Clinical Trial to Evaluate The Immunogenicity and Safety of A Prophylactic Vaccination of Healthcare Providers By Administration of A Heterologous Vaccine Regimen Against Ebola in The Democratic Republic of The Congo: The Study Protocol
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Abstract: This article describes the protocol of an Ebola vaccine clinical trial which investigates the safety and immunogenicity of a two-dose prophylactic Ebola vaccine regimen comprised …		 YNKE LARIVIÈRE et. al. BMJ open 2021-09-28
376 Triangulating Evidence to Infer Pathways That Influence Ebola Virus Disease-Related Stigma and Clinical Findings Among Survivors: An Observational Cohort Study
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Abstract: Visible signs of disease can evoke stigma while stigma contributes to depression and mental illness, sometimes manifesting as somatic symptoms. We assessed these hypotheses among …		 J DANIEL KELLY et. al. The American journal of tropical medicine and hygiene 2021-09-27
377 Assessing The Management of Healthcare Waste for Disease Prevention and Environment Protection at Selected Hospitals in Kinshasa, Democratic Republic of Congo
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Abstract: Incineration is the most used healthcare waste (HCW) disposal method. Disease outbreaks due to Ebola virus and SARS-CoV2 require attention to HCW management to avoid pathogens …		 Gabriel Kalombe Kyomba; Joêl Nkiama Numbi Konde; Diafuka Saila-Ngita; Thomas Kuanda Solo; Guillaume Mbela Kiyombo; Waste management & research : the journal of the … 2021-09-27
378 Ginkgolic Acid Inhibits Coronavirus Strain 229E Infection of Human Epithelial Lung Cells
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Abstract: Since December 2019, the COVID-19 pandemic has affected more than 200 million individuals around the globe and caused millions of deaths. Although there are now multiple vaccines …		 MAIMOONA S BHUTTA et. al. Pharmaceuticals (Basel, Switzerland) 2021-09-26
379 Post-exposure Prophylaxis Following High-risk Contact with Ebola Virus, Using Immunotherapies with Monoclonal Antibodies, in The Eastern Democratic Republic of The Congo: An Emergency Use Program
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Abstract: With the development of therapeutics and vaccine against Ebola virus disease (EVD), the question of post-exposure prophylaxis for high-risk contact has emerged. Immunotherapies …		 MARIE JASPARD et. al. International journal of infectious diseases : IJID : … 2021-09-26
380 COVID-19 Vaccine and The Cold Chain Implications for Global Adoption
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Abstract: The COVID-19 pandemic has spread globally with 190.8 million infected cases and 4.1 million deaths as of July 18, 2021. In absence of any definite antiviral agent availability and …		 Manoja Kumar Das; Indian journal of public health 2021-09-24
381 A Computational Overview on Phylogenetic Characterization, Pathogenic Mutations, and Drug Targets for Ebola Virus Disease
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Abstract: The World Health Organization declared Ebola virus disease (EVD) as the major outbreak in the 20th century. EVD was first identified in 1976 in South Sudan and the Democratic …		 KARTHICK VASUDEVAN et. al. Current opinion in pharmacology 2021-09-24
382 Identification of A Dual Acting SARS-CoV-2 Proteases Inhibitor Through in Silico Design and Step-by-step Biological Characterization
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Abstract: COVID-19 pandemic, starting from the latest 2019, and caused by SARS-CoV-2 pathogen, led to the hardest health-socio-economic disaster in the last century. Despite the tremendous …		 VERONICA DI SARNO et. al. European journal of medicinal chemistry 2021-09-22
383 A Review of THz Technologies for Rapid Sensing and Detection of Viruses Including SARS-CoV-2
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Abstract: Virus epidemics such as Ebola virus, Zika virus, MERS-coronavirus, and others have wreaked havoc on humanity in the last decade. In addition, a coronavirus (SARS-CoV-2) pandemic …		 Naznin Akter; Muhammad Mahmudul Hasan; Nezih Pala; Biosensors 2021-09-22
384 The Suppressor of Cytokine Signalling Family of Proteins and Their Potential Impact on COVID-19 Disease Progression
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Abstract: The family of Suppressor of Cytokine Signalling (SOCS) proteins plays pivotal roles in cytokine and immune regulation. Despite their key roles, little attention has been given to …		 Zheng Yao Low; Ashley Jia Wen Yip; Vincent T K Chow; Sunil K Lal; Reviews in medical virology 2021-09-21
385 Synthesis and Antiviral Activity of Fatty Acyl Conjugates of Remdesivir Against Severe Acute Respiratory Syndrome Coronavirus 2 and Ebola Virus
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Abstract: We report here the synthesis, purification, and characterization of mono- and di-fatty acyl conjugates of remdesivir (RDV) and their in vitro antiviral activity against SAR-CoV-2, …		 NAGLAA SALEM EL-SAYED et. al. European journal of medicinal chemistry 2021-09-21
386 An Update on The Progress of Galidesivir (BCX4430), A Broad-spectrum Antiviral
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Abstract: Galidesivir (BCX4430) is an adenosine nucleoside analog that is broadly active in cell culture against several RNA viruses of various families. This activity has also been shown …		 JUSTIN G JULANDER et. al. Antiviral research 2021-09-20
387 Pandemics Throughout The History
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Abstract: As we move amidst the coronavirus disease 2019 (COVID-19) pandemic, we have witnessed tremendous distress, death, and turmoil of everyday life for more than one year now. However, …		 SHRIKANTH SAMPATH et. al. Cureus 2021-09-20
388 Selection of Filovirus Isolates for Vaccine Development Programs
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Abstract: The continuing outbreaks of ebola virus disease highlight the ongoing threat posed by filoviruses. Fortunately, licensed vaccines and therapeutics are now available for . However, …		 DANIEL N WOLFE et. al. Vaccines 2021-09-19
389 Zoonotic Potential of A Novel Bat Morbillivirus
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Highlight: Here, we identify and characterize a novel morbillivirus from a vespertilionid bat species (Myotis riparius) in Brazil, which we term myotis bat morbillivirus (MBaMV).		 S. IKEGAME et. al. bio.microbiology 2021-09-17
390 The Ebola Virus Soluble Glycoprotein Contributes to Viral Pathogenesis By Activating The MAP Kinase Signaling Pathway
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Abstract: Ebola virus (EBOV) expresses three different glycoproteins (GPs) from its GP gene. The primary product, soluble GP (sGP), is secreted in abundance during infection. EBOV sGP has …		 Wakako Furuyama; Kyle Shifflett; Heinz Feldmann; Andrea Marzi; PLoS pathogens 2021-09-16
391 Filovirus Neutralising Antibodies: Mechanisms of Action and Therapeutic Application
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Abstract: Filoviruses, especially Ebola virus, cause sporadic outbreaks of viral haemorrhagic fever with very high case fatality rates in Africa. The 2013-2016 Ebola epidemic in West Africa …		 ALEXANDER HARGREAVES et. al. Pathogens (Basel, Switzerland) 2021-09-16
392 PANoptosis in Viral Infection: The Missing Puzzle Piece in The Cell Death Field
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Abstract: In the past decade, emerging viral outbreaks like SARS-CoV-2, Zika and Ebola have presented major challenges to the global health system. Viruses are unique pathogens in that they …		 Lam Nhat Nguyen; Thirumala-Devi Kanneganti; Journal of molecular biology 2021-09-16
393 Ebola Virus Can Lie Low and Reactivate After Years in Human Survivors
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 Robert F Garry; Nature 2021-09-16
394 The 2013-2016 Ebola Virus Disease Outbreak in West Africa
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Abstract: The largest, longest, and deadliest ever-recorded outbreak of Ebola virus disease in human history occurred in West Africa from December 2013 to March 2016 causing 28,652 …		 Elijah Ige Ohimain; Daniel Silas-Olu; Current opinion in pharmacology 2021-09-16
395 Comparison of Machine Learning Methods for Estimating Case Fatality Ratios: An Ebola Outbreak Simulation Study
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Abstract: Machine learning (ML) algorithms are now increasingly used in infectious disease epidemiology. Epidemiologists should understand how ML algorithms behave within the context of …		 Alpha Forna; Ilaria Dorigatti; Pierre Nouvellet; Christl A Donnelly; PloS one 2021-09-15
396 Resurgence of Ebola Virus in 2021 in Guinea Suggests A New Paradigm for Outbreaks
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Abstract: Seven years after the declaration of the first epidemic of Ebola virus disease in Guinea, the country faced a new outbreak-between 14 February and 19 June 2021-near the epicentre …		 ALPHA KABINET KEITA et. al. Nature 2021-09-15
397 Low-Valent Calix[4]arene Glycoconjugates Based on Hydroxamic Acid Bearing Linkers As Potent Inhibitors in A Model of Ebola Virus Cis-Infection and HCMV-gB-Recombinant Glycoprotein Interaction with MDDC Cells By Blocking DC-SIGN
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Abstract: In addition to a variety of viral-glycoprotein receptors (e.g., heparan sulfate, Niemann-Pick C1, etc.), dendritic cell-specific intercellular adhesion molecule-3-grabbing …		 KHOULOUD CHAKROUN et. al. Journal of medicinal chemistry 2021-09-15
398 SERINC Proteins Potentiate Antiviral Type I IFN Production and Proinflammatory Signaling Pathways
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Abstract: The SERINC (serine incorporator) proteins are host restriction factors that inhibit infection by HIV through their incorporation into virions. Here, we found that SERINC3 and …		 CONG ZENG et. al. Science signaling 2021-09-14
399 Three-dimensional Insights Into Human Enveloped Viruses in Vitro and in Situ
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Abstract: Viruses can be enveloped or non-enveloped, and require a host cell to replicate and package their genomes into new virions to infect new cells. To accomplish this task, viruses …		 Naveen Vankadari; Doulin C Shepherd; Stephen D Carter; Debnath Ghosal; Biochemical Society transactions 2021-09-14
400 Knowledge, Attitude and Practice of Sudanese Health Care Providers Toward Ebola Virus Outbreak
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Abstract: Ebola virus disease (EVD) is a highly contagious and fatal disease in humans. Healthcare providers (HCPs) are often at the frontline of epidemics and can thus be in jeopardy of …		 Ezzan Kunna; Taro Yamamoto; Sabin Nundu; Calliope Akintije; Isam Elkhidir; Acta medica Okayama 2021-09-13
401 Interferon-Induced HERC5 Inhibits Ebola Virus Particle Production and Is Antagonized By Ebola Glycoprotein
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Abstract: Survival following Ebola virus (EBOV) infection correlates with the ability to mount an early and robust interferon (IFN) response. The host IFN-induced proteins that contribute …		 ERMELA PAPARISTO et. al. Cells 2021-09-13
402 The Impact of Providing End-of-life Care During A Pandemic on The Mental Health and Wellbeing of Health and Social Care Staff: Systematic Review and Meta-synthesis
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Abstract: Disease outbreaks and disasters can result in excess deaths and severe disruption of usual end-of-life care processes. We aimed to: i) synthesise evidence describing the …		 Bryony Porter; Amy Zile; Guy Peryer; Morag Farquhar; Kristy Sanderson; Social science & medicine (1982) 2021-09-13
403 Safety and Immunogenicity of The Two-dose Heterologous Ad26.ZEBOV and MVA-BN-Filo Ebola Vaccine Regimen in Children in Sierra Leone: A Randomised, Double-blind, Controlled Trial
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Abstract: Children account for a substantial proportion of cases and deaths from Ebola virus disease. We aimed to assess the safety and immunogenicity of a two-dose heterologous vaccine …		 MUHAMMED O AFOLABI et. al. The Lancet. Infectious diseases 2021-09-13
404 Safety and Long-term Immunogenicity of The Two-dose Heterologous Ad26.ZEBOV and MVA-BN-Filo Ebola Vaccine Regimen in Adults in Sierra Leone: A Combined Open-label, Non-randomised Stage 1, and A Randomised, Double-blind, Controlled Stage 2 Trial
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Abstract: The Ebola epidemics in west Africa and the Democratic Republic of the Congo highlight an urgent need for safe and effective vaccines to prevent Ebola virus disease. We aimed to …		 DAVID ISHOLA et. al. The Lancet. Infectious diseases 2021-09-13
405 Ebola Vaccines for Mass Immunisation in Affected Regions
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 Selidji Todagbe Agnandji; Marguerite Massinga Loembe; The Lancet. Infectious diseases 2021-09-13
406 Third-generation Smallpox Vaccine Strain-based Recombinant Vaccines for Viral Hemorrhagic Fevers
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Abstract: Vaccinia virus has been used as a smallpox vaccine. Now that smallpox has been eradicated, the vaccinia virus is expected to be used as a bioterrorism countermeasure and a …		 Tomoki Yoshikawa; Vaccine 2021-09-11
407 The Impact of The 2014 Ebola Epidemic on HIV Disease Burden and Outcomes in Liberia West Africa
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Abstract: Detailed longitudinal studies of HIV-positive individuals in West Africa are lacking. Here the HIV prevalence, incidence, all-cause mortality, and the proportion of individuals …		 SOKA J MOSES et. al. PloS one 2021-09-10
408 Marburg and Ebola Virus MRNA 3′ Untranslated Regions Contain Negative Regulators of Translation That Are Modulated By ADAR1 Editing
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Abstract: The filovirus family includes deadly pathogens such as Ebola virus (EBOV) and Marburg virus (MARV). A substantial portion of filovirus genomes encode 5′ and 3′ untranslated …		 Sudip Khadka; Caroline G Williams; Joyce Sweeney-Gibbons; Christopher F Basler; Journal of virology 2021-09-09
409 Bats and Viruses: A Death-defying Friendship
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Abstract: Bats have a primeval evolutionary origin and have adopted various survival methods. They have played a central role in the emergence of various viral diseases. The sustenance of a …		 PARAKRITI GUPTA et. al. Virusdisease 2021-09-09
410 The Methanolic Extract of Perilla Frutescens Robustly Restricts Ebola Virus Glycoprotein-Mediated Entry
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Abstract: Ebola virus (EBOV), one of the most infectious human viruses and a leading cause of viral hemorrhagic fever, imposes a potential public health threat with several recent …		 YU-TING KUO et. al. Viruses 2021-09-08
411 The First 8 Months of COVID-19 Pandemic in Three West African Countries: Leveraging Lessons Learned from Responses to The 2014-2016 Ebola Virus Disease Outbreak
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Abstract: Experience gained from responding to major outbreaks may have influenced the early coronavirus disease-2019 (COVID-19) pandemic response in several countries across Africa. We …		 BENIDO IMPOUMA et. al. Epidemiology and infection 2021-09-08
412 The Rapid, Massive Growth of COVID-19 Authors in The Scientific Literature
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Abstract: We examined the extent to which the scientific workforce in different fields was engaged in publishing COVID-19-related papers. According to Scopus (data cut, 1 August 2021), 210 …		 John P A Ioannidis; Maia Salholz-Hillel; Kevin W Boyack; Jeroen Baas; Royal Society open science 2021-09-07
413 [Risk Perception Among Health Professionals in The First Case of Secondary Ebola Infection in Spain. Case Study.]
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Abstract: In 2014, the first case of secondary Ebola infection outside Africa detected in Spain, caused a sense of global threat. This study assess Risk Perception amongst the health …		 Ana Ayuso-Álvarez; Teresa Blasco Hernández; Agustín Benito Llanes; Revista espanola de salud publica 2021-09-07
414 The Nucleoside Antiviral Prodrug Remdesivir in Treating COVID-19 and Beyond with Interspecies Significance
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Abstract: Infectious pandemics result in hundreds and millions of deaths, notable examples of the Spanish Flu, the Black Death and smallpox. The current pandemic, caused by SARS-CoV-2 …		 Daisy Yan; One Hyuk Ra; Bingfang Yan; Animal diseases 2021-09-07
415 Optimization of Single Dose VSV-based COVID-19 Vaccination in Hamsters
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Highlight: Here, we demonstrate the immunogenicity and protective efficacy of two vesicular stomatitis virus (VSV)-based vaccines encoding the SARS-CoV-2 spike protein either alone (VSV-SARS2) or in combination with the Ebola virus glycoprotein (VSV-SARS2-EBOV).		 K. L. O’DONNELL et. al. bio.microbiology 2021-09-03
416 Actor-Network Analysis of Community-Based Organisations in Health Pandemics: Evidence from Covid-19 Response in Freetown, Sierra Leone
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Abstract: Freetown is confronted with health-related risks that are compounded by rapid unplanned urbanisation and weak capacities of local government institutions. Addressing such …		 LOUIS KUSI FRIMPONG et. al. Disasters 2021-09-03
417 Ebola Virus Protein VP40 Binding to Sec24c for Transport to The Plasma Membrane
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Abstract: Outbreaks of the Ebola virus (EBOV) continue to occur and while a vaccine and treatment are now available, there remains a dearth of options for those who become sick with EBOV …		 NISHA BHATTARAI et. al. Proteins 2021-09-03
418 Temporal Evolution of The Humoral Antibody Response After Ebola Virus Disease in Guinea: A 60-month Observational Prospective Cohort Study
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Abstract: Insufficient long-term data are available on antibody kinetics in survivors of Ebola virus disease (EVD). Likewise, few studies, with very small sample sizes, have investigated …		 MAMADOU SALIOU KALIFA DIALLO et. al. The Lancet. Microbe 2021-09-03
419 Optimization of Single Dose VSV-based COVID-19 Vaccination in Hamsters
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Abstract: The ongoing COVID-19 pandemic has resulted in global effects on human health, economic stability, and social norms. The emergence of viral variants raises concerns about the …		 KYLE L O’DONNELL et. al. bioRxiv : the preprint server for biology 2021-09-03
420 Plant-based Vaccine Research Development Against Viral Diseases with Emphasis on Ebola Virus Disease: A Review Study
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Abstract: Ebola virus infection results in the fast onset of severe acute haemorrhagic fever with high mortality. The Ebola virus is labelled as a category A pathogen. Vaccines against the …		 Satyajit Tripathy; Barsha Dassarma; Manojit Bhattacharya; Motlalepula Gilbert Matsabisa; Current opinion in pharmacology 2021-09-01
421 Correction To: Partnership for Research on Ebola VACcination (PREVAC): Protocol of A Randomized, Double-blind, Placebo-controlled Phase 2 Clinical Trial Evaluating Three Vaccine Strategies Against Ebola in Healthy Volunteers in Four West African Countries
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 MOSES BADIO et. al. Trials 2021-09-01
422 Conserved Immunogenic Peptides of Ebola Glycoprotein Elicit Immune Response in Human Peripheral Blood Mononuclear Cells
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Abstract: In the past 45 years, ebolaviruses have periodically caused epidemics on the African continent. In December 2019, approval of a recombinant vector-based EBOV vaccine, named …		 Sahil Jain; Manoj Baranwal; Microbiology and immunology 2021-08-31
423 A Mixed-methods Investigation to Understand and Improve The Scaled-up Infection Prevention and Control in Primary Care Health Facilities During The Ebola Virus Disease Epidemic in Sierra Leone
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Abstract: The 2014-2015 Ebola epidemic in West Africa became a humanitarian crisis that exposed significant gaps in infection prevention and control (IPC) capacity in primary care …		 Lara Shiu-Yi Ho; Ruwan Ratnayake; Rashid Ansumana; Hannah Brown; BMC public health 2021-08-31
424 Review: Insights on Current FDA-Approved Monoclonal Antibodies Against Ebola Virus Infection
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Abstract: The unprecedented 2013-2016 West Africa Ebola outbreak accelerated several medical countermeasures (MCMs) against Ebola virus disease (EVD). Several investigational products (IPs) …		 Olivier Tshiani Mbaya; Philippe Mukumbayi; Sabue Mulangu; Frontiers in immunology 2021-08-30
425 The Good, The Bad and The Ugly of Testicular Immune Regulation: A Delicate Balance Between Immune Function and Immune Privilege
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Abstract: The testis is one of several immune privilege sites. These sites are necessary to decrease inflammation and immune responses that could be damaging to the host. For example, …		 Gurvinder Kaur; Kandis Wright; Saguna Verma; Allan Haynes; Jannette M Dufour; Advances in experimental medicine and biology 2021-08-28
426 Therapeutics Development for Ebola Virus Disease: A Recent Scenario
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Abstract: The Ebola virus disease is a deadly pathogenic disease caused by the Ebola virus. It has been observed that this disease causes a high case-fatality rate. Several species of this …		 Chiranjib Chakraborty; Current opinion in pharmacology 2021-08-28
427 Application of Pseudotyped Virus Particles to Monitor Ebola Virus and SARS-CoV-2 Viral Entry in Human Cell Lines
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Abstract: Experimental work on highly pathogenic viruses such as Ebola virus (EBOV) and severe acute respiratory syndrome coronavirus-2 requires high-level biosafety facilities. Here, we …		 Madeleine Eichler; Ebru Aksi; Josef Pfeilschifter; Gergely Imre; STAR protocols 2021-08-27
428 Marta Lado-Ebola, HIV, Sexual Health and More
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 Tony Kirby; The Lancet. Infectious diseases 2021-08-27
429 Vesicular Stomatitis Virus: From Agricultural Pathogen to Vaccine Vector
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Abstract: Vesicular stomatitis virus (VSV), which belongs to the genus of the family , is a well studied livestock pathogen and prototypic non-segmented, negative-sense RNA virus. Although …		 GUODONG LIU et. al. Pathogens (Basel, Switzerland) 2021-08-27
430 An Overview of The Preclinical Discovery and Development of Remdesivir for The Treatment of Coronavirus Disease 2019 (COVID-19)
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Abstract: Remdesivir (RDV) is an inhibitor of the viral RNA-dependent RNA polymerases that are active in some RNA viruses, including the Ebola virus and zoonotic coronaviruses. When severe …		 PASQUALE PAGLIANO et. al. Expert opinion on drug discovery 2021-08-27
431 [Ebola Re-emergence in The Context of Covid-19]
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Abstract: Ebola is the most vicious virus in Africa. International organisations have worked to contain the various outbreaks and a vaccine is being administered to the population. This …		 Adélie Oger; Actualites pharmaceutiques 2021-08-26
432 A Naturally Occurring Polymorphism in The Base of Sudan Virus Glycoprotein Decreases Glycoprotein Stability in A Species-Dependent Manner
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Abstract: Sudan virus (SUDV) is one of five filoviruses that compose the genus that has been responsible for episodic outbreaks in Central Africa. While the SUDV glycoprotein (GP) structure …		 NICHOLAS J LENNEMANN et. al. Journal of virology 2021-08-25
433 Cross-Neutralisation of Novel Bombali Virus By Ebola Virus Antibodies and Convalescent Plasma Using An Optimised Pseudotype-Based Neutralisation Assay
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Abstract: Ebolaviruses continue to pose a significant outbreak threat, and while Ebola virus (EBOV)-specific vaccines and antivirals have been licensed, efforts to develop candidates …		 EMMA M BENTLEY et. al. Tropical medicine and infectious disease 2021-08-25
434 Mapping of Ebola Virus Spillover: Suitability and Seasonal Variability at The Landscape Scale
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Highlight: We used a Geographic Information System-based multicriteria evaluation (GIS-MCE), a knowledge-based approach, to identify areas suitable for Ebola virus spillover to humans in regions of Guinea, Congo and Gabon where Ebola viruses already emerged.		 LARISA LEE-CRUZ et. al. arxiv-q-bio.PE 2021-08-24
435 Ebola and COVID-19 in Democratic Republic of Congo: Grappling with Two Plagues at Once
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Abstract: In February 2021, a new Ebola virus disease outbreak was confirmed amid the COVID-19 pandemic in the Democratic Republic of Congo. Although the country has successfully contained …		 FATIMA MUHAMMAD ASAD KHAN et. al. Tropical medicine and health 2021-08-24
436 Interruption of Tuberculosis Detection and Care During The Ebola Virus Disease Epidemic (2014-2015) in Liberia: Time-series Analyses for 2013-2017
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Abstract: Interrupted time-series analyses, using 5 years of routinely collected health information system data, were conducted to estimate the magnitude of impact of the 2014-2015 Ebola …		 KEITH L GRAY et. al. International journal of infectious diseases : IJID : … 2021-08-22
437 Perceptions of Ebola Virus Disease Among The Bambuti Hunter Group: A Mixed-methods Study
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Abstract: The second largest Ebola virus disease (EVD) epidemic occurred in the Democratic Republic of the Congo (DRC) from 2018-20. The Bambuti, a hunter population in the Ituri Forest of …		 Ella M E Forgie; Kasereka Masumbuko Claude; Michael T Hawkes; Pathogens and global health 2021-08-22
438 The Epidemiology of Emerging Infectious Diseases and Pandemics
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Abstract: The spectrum of human pathogens and the infectious diseases they cause is continuously changing through evolution, selection and changes in the way human populations interact with …		 H Rogier van Doorn; Medicine (Abingdon, England : UK ed.) 2021-08-21
439 The Rapid, Massive Growth of COVID-19 Authors in The Scientific Literature
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Highlight: We examined the extent to which the scientific workforce in different fields was engaged in publishing COVID-19-related papers.		 J. Ioannidis; M. Salholz-Hillel; K. Boyack; J. Baas; bio.scientific-communication-and-education 2021-08-21
440 The Microbiota-related Coinfections in COVID-19 Patients: A Real Challenge
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Abstract: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of ongoing global pandemic of coronavirus disease 2019 (COVID-19), has infected millions of people …		 RANJAN K MOHAPATRA et. al. Beni-Suef University journal of basic and applied sciences 2021-08-21
441 Modulation of Immune Response in Ebola Virus Disease
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Abstract: Ebola virus disease targets and destroys immune cells, including macrophages and dendritic cells, leading to impairment of host response. After infection, a combination of …		 GOUTAM BANERJEE et. al. Current opinion in pharmacology 2021-08-20
442 [SARS-CoV-2 Vaccines and Reaction of The Immune System. Can the epidemic Spread of The Virus Be Prevented By Vaccination?]
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Abstract: Since the end of 2019 a new coronavirus, SARS-CoV-2, first identified in Wuhan, China, is spreading around the world partially associated with a high death toll. Besides hygienic …		 Jonas Schmidt; Frithjof Blessing; Lutz Gürtler; Deutsche medizinische Wochenschrift (1946) 2021-08-20
443 The Ebola Virus Interferon Antagonist VP24 Undergoes Active Nucleocytoplasmic Trafficking
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Abstract: Viral interferon (IFN) antagonist proteins mediate evasion of IFN-mediated innate immunity and are often multifunctional, with distinct roles in viral replication. The Ebola virus …		 Angela R Harrison; Cassandra T David; Stephen M Rawlinson; Gregory W Moseley; Viruses 2021-08-19
444 Pandemic, Epidemic, Endemic: B Cell Repertoire Analysis Reveals Unique Anti-viral Responses to SARS-CoV-2, Ebola and Respiratory Syncytial Virus
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Highlight: Detailed compositional and lineage analysis of long read IGH repertoire sequencing, combining examples of pandemic, epidemic and endemic viral infections with control and vaccination samples, demonstrates general responses including increased use of IGHV4-39 in both EBOV and COVID-19 infection cohorts.		 A. STEWART et. al. bio.immunology 2021-08-19
445 Health Facilities’ Readiness for Safe Surgical Care Provision in Uganda and The Eastern Democratic Republic of Congo During Ebola and COVID-19 Era
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Abstract: This study aimed to assess health facilities’ readiness to provide safe surgical care during Ebola and COVID-19 era in Uganda and in the Eastern DR Congo. A cross-sectional study …		 FRANCK KATEMBO SIKAKULYA et. al. BMC health services research 2021-08-18
446 Global Research Activity on Health System Preparedness Against Viral Infectious Disease Outbreaks
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Abstract: The present study aimed to give an overview of research publications on health system preparedness against viral infectious disease outbreaks. A bibliometric method was …		 Waleed M Sweileh; Disaster medicine and public health preparedness 2021-08-18
447 Ivory Coast Rolls Out Ebola Vaccine After First Confirmed Case Since 1994
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 Luke Taylor; BMJ (Clinical research ed.) 2021-08-18
448 Atoltivimab/maftivimab/odesivimab (Inmazeb) Combination to Treat Infection Caused By Zaire Ebolavirus
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Abstract: Zaire ebolavirus has been responsible for several catastrophic outbreaks with a high mortality rate. Unfortunately, there were no approved therapies or vaccines to treat or …		 D Saxena; G Kaul; A Dasgupta; S Chopra; Drugs of today (Barcelona, Spain : 1998) 2021-08-18
449 Recombinant Protein Filovirus Vaccines Protect Cynomolgus Macaques From Ebola, Sudan, and Marburg Viruses
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Abstract: Ebola (EBOV), Marburg (MARV) and Sudan (SUDV) viruses are the three filoviruses which have caused the most fatalities in humans. Transmission from animals into the human …		 AXEL T LEHRER et. al. Frontiers in immunology 2021-08-18
450 Pandemic Risk Management: Resources Contingency Planning and Allocation
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Abstract: The repeated history of pandemics, such as SARS, H1N1, Ebola, Zika, and COVID-19, has shown that pandemic risk is inevitable. Extraordinary shortages of medical resources have …		 Xiaowei Chen; Wing Fung Chong; Runhuan Feng; Linfeng Zhang; Insurance, mathematics & economics 2021-08-17
451 Delayed Disease in Cynomolgus Macaques Exposed to Ebola Virus By An Intranasal Route
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Abstract: Ebola virus remains a significant public health concern due to high morbidity and mortality rates during recurrent outbreaks in endemic areas. Therefore, the development of …		 SARA C JOHNSTON et. al. Frontiers in immunology 2021-08-16
452 Psychology and The Threat of Contagion: Feeling Vulnerable to A Disease Moderates The Link Between Xenophobic Thoughts and Support for Ingroup-Protective Actions
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Abstract: The widespread threat of contagious disease disrupts not only everyday life but also psychological experience. Building on findings regarding xenophobic responses to contagious …		 Heejung S Kim; Kimin Eom; Roxie Chuang; David K Sherman; Personality & social psychology bulletin 2021-08-16
453 Remdesivir for The Treatment of COVID 19: Review of The Pharmacological Properties, Safety and Clinical Effectiveness
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Abstract: Remdesivir is a nucleoside analog that inhibits viral RNA replication by blocking RNA-dependent RNA polymerase. First developed and tested during the Ebola epidemic, repurposed, …		 Ashesha Mechineni; Hagar Kassab; Rajapriya Manickam; Expert opinion on drug safety 2021-08-16
454 Barriers and Opportunities for Sustainable Hand Hygiene Interventions in Rural Liberian Hospitals
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Abstract: Hand hygiene is central to hospital infection control. During the 2014-2016 West Africa Ebola virus disease epidemic in Liberia, gaps in hand hygiene infrastructure and health …		 LUCY K TANTUM et. al. International journal of environmental research and public … 2021-08-14
455 [Challenges in The Management of Haemorrhagic Fevers: Ebola Virus Disease Experience in The North Kivu Province and Ituri Province (Democratic Republic of Congo) and The Importance of Early Diagnosis]
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Abstract: Ebola virus disease is a serious, often fatal disease whose case-fatality rate can be 90%. Our short-term goal is to create awareness on Ebola virus signs and to encourage early …		 CRISS KOBA MJUMBE et. al. The Pan African medical journal 2021-08-13
456 Measuring The Scientific Effectiveness of Contact Tracing: Evidence from A Natural Experiment
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Abstract: Contact tracing has for decades been a cornerstone of the public health approach to epidemics, including Ebola, severe acute respiratory syndrome, and now COVID-19. It has not yet …		 Thiemo Fetzer; Thomas Graeber; Proceedings of the National Academy of Sciences of the … 2021-08-13
457 Transcriptional Analysis of Infection With Early or Late Isolates From The 2013-2016 West Africa Ebola Virus Epidemic Does Not Suggest Attenuated Pathogenicity As A Result of Genetic Variation
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Abstract: The 2013-2016 West Africa Ebola virus (EBOV) epidemic caused by the EBOV-Makona isolate is the largest and longest recorded to date. It incurred over 28,000 infections and ∼11,000 …		 Kevin J Maroney; Amanda N Pinski; Andrea Marzi; Ilhem Messaoudi; Frontiers in microbiology 2021-08-13
458 Zoonotic Risk Factors Associated with Seroprevalence of Ebola Virus GP Antibodies in The Absence of Diagnosed Ebola Virus Disease in The Democratic Republic of Congo
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Abstract: Ebola virus (EBOV) is a zoonotic filovirus spread through exposure to infected bodily fluids of a human or animal. Though EBOV is capable of causing severe disease, referred to as …		 ANNA BRATCHER et. al. PLoS neglected tropical diseases 2021-08-12
459 Novel Quinolone Derivatives Targeting Human Dihydroorotate Dehydrogenase Suppress Ebola Virus Infection in Vitro
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Abstract: Ebola virus (EBOV) has emerged as a significant public health concern since the 2013-2016 outbreak in West Africa. Currently, no effective antiviral treatments have been approved …		 MINGLI GONG et. al. Antiviral research 2021-08-12
460 Mixed-methods Assessment of Health and Mental Health Characteristics and Barriers to Healthcare for Ebola Survivors in Beni, Butembo and Katwa Health Zones of The Democratic Republic of Congo
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Abstract: Health and mental health characteristics of all respondents, barriers to accessing health and mental health services and the characteristics and those most at risk for mental …		 Lynn Lieberman Lawry; Nancy Stroupe Kannappan; Covadonga Canteli; William Clemmer; BMJ open 2021-08-11
461 Bundibugyo Ebolavirus Survival Is Associated with Early Activation of Adaptive Immunity and Reduced Myeloid-Derived Suppressor Cell Signaling
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Abstract: Ebolaviruses Bundibugyo virus (BDBV) and Ebola virus (EBOV) cause fatal hemorrhagic disease in humans and nonhuman primates. While the host response to EBOV is well characterized, …		 COURTNEY WOOLSEY et. al. mBio 2021-08-10
462
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Abstract: The objective of this study was to identify the factors that influenced the poor performance of the Community Observatory on Access to Health Services (OCASS) project during its …		 Thierno Oumar Fofana; Werner Soors; Abdoulaye Sow; Alexandre Delamou; Bruno Marchal; Sante publique (Vandoeuvre-les-Nancy, France) 2021-08-10
463 Repurposing Psychotropic Agents for Viral Disorders: Beyond Covid
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Abstract: Recent reports have highlighted the possible role of the antipsychotic chlorpromazine and the antidepressant fluvoxamine as anti-coronavirus disease 2019 (COVID-19) agents. The …		 Shea R Golden; Donald L Rosenstein; Tom Belhorn; Julie Blatt; Assay and drug development technologies 2021-08-10
464 Identification and Characterization of Defective Viral Genomes in Ebola Virus-Infected Rhesus Macaques
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Abstract: Ebola virus (EBOV), of the family , is an RNA virus that can cause a hemorrhagic fever with a high mortality rate. Defective viral genomes (DVGs) are truncated genomes that have …		 REBECCA I JOHNSON et. al. Journal of virology 2021-08-10
465 Comparison of The Efficacy of Disinfectant Pre-impregnated Wipes for Decontaminating Stainless Steel Carriers Experimentally Inoculated With Ebola Virus and Vesicular Stomatitis Virus
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Abstract: The authors evaluated four disinfectant pre-impregnated wipes (DPW) for efficacy against Ebola virus Makona variant (EBOV) and vesicular stomatitis virus (VSV), Indiana serotype. …		 TODD A CUTTS et. al. Frontiers in public health 2021-08-10
466 Single Dose RVSVΔG-JUNVGP Vaccine Protects Guinea Pigs Against Lethal Junin Virus Challenge
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Abstract: Junin virus (JUNV) is a pathogen of biodefense importance due to its potential for aerosol transmission and mortality rates reaching 30%. Currently, there are no JUNV vaccines …		 TERESA E SORVILLO et. al. NPJ vaccines 2021-08-09
467 A Linear Noise Approximation for Stochastic Epidemic Models Fit to Partially Observed Incidence Counts
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Abstract: Stochastic epidemic models (SEMs) fit to incidence data are critical to elucidating outbreak dynamics, shaping response strategies, and preparing for future epidemics. SEMs …		 Jonathan Fintzi; Jon Wakefield; Vladimir N Minin; Biometrics 2021-08-09
468 Use of Iris Scanning for Biometric Recognition of Healthy Adults Participating in An Ebola Vaccine Trial in The Democratic Republic of The Congo: Mixed Methods Study
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Abstract: A partnership between the University of Antwerp and the University of Kinshasa implemented the EBOVAC3 clinical trial with an Ebola vaccine regimen administered to health care …		 TRÉSOR ZOLA MATUVANGA et. al. Journal of medical Internet research 2021-08-09
469 Enabling Artificial Intelligence for Genome Sequence Analysis of COVID-19 and Alike Viruses
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Abstract: Recent pandemic of COVID-19 (Coronavirus) caused by severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) has been growing lethally with unusual speed. It has infected …		 Imran Ahmed; Gwanggil Jeon; Interdisciplinary sciences, computational life sciences 2021-08-06
470 COVID-19, Ebola Virus Disease, and Nipah Virus Infection Reclassification As Novel Acute Immune Dysrhythmia Syndrome (n-AIDS): Potential Crucial Role for Immunomodulators
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Abstract: In this manuscript, COVID-19, Ebola virus disease, Nipah virus infection, SARS, and MERS are suggested to be considered for a novel immunological reclassification as acute onset …		 Mina T Kelleni; Immunologic research 2021-08-06
471 Agent-based Analysis of Contagion Events According to Sourcing Locations
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Abstract: The first human infected with the Covid-19 virus was traced to a seafood market in Wuhan, China. Research shows that there are comparable types of viruses found in different and …		 Mijat Kustudic; Ben Niu; Qianying Liu; Scientific reports 2021-08-06
472 Anti-Ebola: An Initiative to Predict Ebola Virus Inhibitors Through Machine Learning
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Abstract: Ebola virus is a deadly pathogen responsible for a frequent series of outbreaks since 1976. Despite various efforts from researchers worldwide, its mortality and fatality are …		 Akanksha Rajput; Manoj Kumar; Molecular diversity 2021-08-06
473 Development and Implementation of The Ebola Exposure Window Calculator: A Tool for Ebola Virus Disease Outbreak Field Investigations
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Abstract: During an Ebola virus disease (EVD) outbreak, calculating the exposure window of a confirmed case can assist field investigators in identifying the source of infection and …		 AMY WHITESELL et. al. PloS one 2021-08-05
474 Genome Structure and Genetic Diversity in The Ebola Virus
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Abstract: Ebola is a deadly pathogen responsible for Ebola virus disease, first came to prominence in the year 1976. This rapidly evolving virus imposed a serious threat to the human …		 Sanmitra Ghosh; Abinit Saha; Saikat Samanta; Rudra P Saha; Current opinion in pharmacology 2021-08-04
475 Laboratory Diagnosis of Tropical Infections
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Abstract: (1) Blood culture is the gold standard for the diagnosis of bacterial infections. (2) Bone marrow culture is more sensitive than blood culture even in patients with enteric fever …		 Shaoli Basu; Anjali Shetty; Indian journal of critical care medicine : peer-reviewed, … 2021-08-04
476 Ecology of Ebolaviruses
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Abstract: Africa is becoming known for the emergence and re-emergence of Ebola virus. The virus, which was initially restricted to East and Central Africa, is now emerging in West Africa. …		 Elijah Ige Ohimain; Current opinion in pharmacology 2021-08-03
477 Suitability of Google Trends™ for Digital Surveillance During Ongoing COVID-19 Epidemic: A Case Study from India
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Abstract: Digital surveillance has shown mixed results as a supplement to traditional surveillance. Google Trends™ (GT) (Google, Mountain View, CA, United States) has been used for digital …		 Parmeshwar Satpathy; Sanjeev Kumar; Pankaj Prasad; Disaster medicine and public health preparedness 2021-08-03
478 Impact of Poor Disease Surveillance System on COVID-19 Response in Africa: Time to Rethink and Rebuilt
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Abstract: Infectious disease outbreaks have long posed a public health threat, especially in Africa, where the incidence of infectious outbreaks has risen exponentially. Although, Africa …		 ABDULLAHI TUNDE ABORODE et. al. Clinical epidemiology and global health 2021-08-03
479 Recombinant Lloviu Virus As A Model to Study Inaccessible Zoonotic Viruses
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Highlight: We leveraged these data to generate recombinant full-length LLOV clones and rescue infectious virus.		 A. J. HUME et. al. bio.microbiology 2021-08-02
480 Non-canonical Proline-tyrosine Interactions with Multiple Host Proteins Regulate Ebola Virus Infection
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Abstract: The Ebola virus VP30 protein interacts with the viral nucleoprotein and with host protein RBBP6 via PPxPxY motifs that adopt non-canonical orientations, as compared to other …		 JYOTI BATRA et. al. The EMBO journal 2021-08-02
481 Global Health Security As It Pertains to Zika, Ebola, and COVID-19
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Abstract: Due to the impact of the COVID-19 pandemic this past year, we have witnessed a significant acceleration in the science, technology, and policy of global health security. This …		 Jaspreet Pannu; Michele Barry; Current opinion in infectious diseases 2021-08-02
482 Analytical Estimation of Data-Motivated Time-Dependent Disease Transmission Rate: An Application to Ebola and Selected Public Health Problems
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Abstract: Obtaining reasonable estimates for transmission rates from observed data is a challenge when using mathematical models to study the dynamics of ?infectious? diseases, like Ebola. …		 ANUJ MUBAYI et. al. Tropical medicine and infectious disease 2021-07-31
483 Simultaneous Detection of Ebola Virus and Pathogens Associated With Hemorrhagic Fever By An Oligonucleotide Microarray
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Abstract: Ebola virus infection causes severe hemorrhagic fever, and its mortality rates varied from 25 to 90% in the previous outbreaks. The highly infectious and lethal nature of this …		 WENWU YAO et. al. Frontiers in microbiology 2021-07-30
484 A SEIR Model with Memory Effects for The Propagation of Ebola-like Infections and Its Dynamically Consistent Approximation
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Abstract: We present and analyze a nonstandard numerical method to solve an epidemic model with memory that describes the propagation of Ebola-type diseases. The epidemiological system …		 ZAFAR IQBAL et. al. Computer methods and programs in biomedicine 2021-07-29
485 Ebola Outbreaks: A Stress Test of The Preparedness of Medicines Regulatory Systems for Public Health Crises
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Abstract: In a globalized world, infectious diseases of international concern are inevitable. When they (re-)emerge, the regulatory system works towards mitigating their impact. Ebola …		 Rafael Amaral; Carla Torre; João Rocha; Bruno Sepodes; Drug discovery today 2021-07-28
486 Ebola Virus Requires Phosphatidylserine Scrambling Activity for Efficient Budding and Optimal Infectivity
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Abstract: Ebola virus (EBOV) attaches to target cells using two categories of cell surface receptors: C-type lectins and phosphatidylserine (PS) receptors. PS receptors typically bind to …		 MARISSA D ACCIANI et. al. Journal of virology 2021-07-28
487 Remember Ebola: Stop Mass Death in Africa
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 Mosoka Fallah; Nature 2021-07-28
488 Recent Developments and Strategies of Ebola Virus Vaccines
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Abstract: The Filovirus family member, Ebola virus (EBOV), is a highly infectious pathogen responsible for viral hemorrhagic fever. EBOV has a fatality rate in the range 50%-90% in …		 Ashish Ranjan Sharma; Yeon-Hee Lee; Sudarshini Nath; Sang-Soo Lee; Current opinion in pharmacology 2021-07-27
489 Immunoinformatics Aided Design of Peptide-based Vaccines Against Ebolaviruses
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Abstract: Ebolaviruses are at the forefront of emerging viruses and present a very perceptible threat to global peace and harmony. In the last decade, Ebola virus disease has claimed more …		 Sahil Jain; Manoj Baranwal; Vitamins and hormones 2021-07-27
490 Potential Test-negative Design Study Bias in Outbreak Settings: Application to Ebola Vaccination in Democratic Republic of Congo
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Abstract: Infectious disease outbreaks present unique challenges to study designs for vaccine evaluation. Test-negative design (TND) studies have previously been used to estimate vaccine …		 Carl A B Pearson; W John Edmunds; Thomas J Hladish; Rosalind M Eggo; International journal of epidemiology 2021-07-27
491 Functional Interactomes of The Ebola Virus Polymerase Identified By Proximity Proteomics in The Context of Viral Replication
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Abstract: Ebola virus (EBOV) critically depends on the viral polymerase to replicate and transcribe the viral RNA genome in the cytoplasm of host cells, where cellular factors can …		 JINGRU FANG et. al. Cell reports 2021-07-26
492 A Yeast BiFC-seq Method for Genome-wide Interactome Mapping
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Abstract: Genome-wide physical protein-protein interaction (PPI) mapping remains a major challenge for current technologies. Here, we report a high-efficiency yeast bimolecular fluorescence …		 LIMIN SHANG et. al. Genomics, proteomics & bioinformatics 2021-07-24
493 ‘Learn from The Lessons and Don’t Forget Them’: Identifying Transferable Lessons for COVID-19 from Meningitis A, Yellow Fever and Ebola Virus Disease Vaccination Campaigns
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Abstract: COVID-19 vaccines are now being distributed to low- and middle-income countries (LMICs), with global urgency surrounding national vaccination plans. LMICs have significant …		 JULIE COLLINS et. al. BMJ global health 2021-07-19
494 Learn from The Lessons and Don’t Forget Them: Identifying Transferable Lessons for COVID-19 from Meningitis A, Yellow Fever, and Ebola Virus Disease Vaccination Campaigns
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Highlight: Methods: We conducted a rapid literature review and 24 semi-structured interviews with technical experts who had direct implementation experience with the selected vaccines in Africa and South America.		 J. COLLINS et. al. med.public-and-global-health 2021-07-19
495 The Establishment and Application of Mobile Electronic Surveillance System for Infectious Diseases with The Help of China – Sierra Leone, 2016-Present
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Abstract: Infectious disease surveillance has long been a challenge for low-income countries like Sierra Leone. Traditional approaches based on paper and Short Message Service (SMS) were …		 GUANGYU ZHAO et. al. China CDC weekly 2021-07-19
496 Epidemics, Pandemics, and Social Conflict: Lessons from The Past and Possible Scenarios for COVID-19
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Abstract: Since COVID-19 broke out, there has been renewed interest in understanding the economic and social dynamics of historical and more recent epidemics and pandemics, from the plagues …		 Remi Jedwab; Amjad M Khan; Jason Russ; Esha D Zaveri; World development 2021-07-17
497 What Effect Might Border Screening Have on Preventing Importation of COVID-19 Compared with Other Infections? A Modelling Study
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Highlight: In this paper, we describe a simple Monte Carlo based model that incorporates the epidemiology of COVID-19 to investigate the potential benefit of requiring all travellers to undergo thorough screening upon arrival.		 D. Bays; E. Bennett; T. Finnie; med.epidemiology 2021-07-17
498 In Silico Analyses and Experimental Validation of The MHC Class-I Restricted Epitopes of Ebolavirus GP
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Abstract: Ebolavirus (EBOV) causes an extremely high mortality and prevalence disease called Ebola virus disease (EVD). There is only one glycoprotein (GP) on the virus particle surface, …		 YANG LIU et. al. International immunology 2021-07-16
499 Poly-l-lysine Glycoconjugates Inhibit DC-SIGN-mediated Attachment of Pandemic Viruses
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Abstract: The C-type lectin receptor DC-SIGN mediates interactions with envelope glycoproteins of many viruses such as SARS-CoV-2, ebola, and HIV and contributes to virus internalization …		 JONATHAN CRAMER et. al. ChemMedChem 2021-07-16
500 CryoEM Structure of The Nipah Virus Nucleocapsid Assembly
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Abstract: Nipah and its close relative Hendra are highly pathogenic zoonotic viruses, storing their ssRNA genome in a helical nucleocapsid assembly formed by the N protein, a major viral …		 De-Sheng Ker; Huw T Jenkins; Sandra J Greive; Alfred A Antson; PLoS pathogens 2021-07-16
501 Proteo-Genomic Analysis Identifies Two Major Sites of Vulnerability on Ebolavirus Glycoprotein for Neutralizing Antibodies in Convalescent Human Plasma
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Abstract: Three clinically relevant ebolaviruses – Ebola (EBOV), Bundibugyo (BDBV), and Sudan (SUDV) viruses, are responsible for severe disease and occasional deadly outbreaks in Africa. …		 PAVLO GILCHUK et. al. Frontiers in immunology 2021-07-16
502 Construction and Evaluation of DNA Vaccine Encoding Ebola Virus Glycoprotein Fused with Lysosome-associated Membrane Protein
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Abstract: Ebola virus (EBOV) of the genus Ebolavirus belongs to the family Filoviridae, which cause disease in both humans and non-human primates. Zaire Ebola virus accounts for the highest …		 YANG LIU et. al. Antiviral research 2021-07-16
503 Immunogenicity and Safety of Ebola Virus Vaccines in Healthy Adults: A Systematic Review and Network Meta-analysis
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Abstract: Clinical development of Ebola virus vaccines (EVV) was accelerated by the West African Ebola virus epidemic which remains the deadliest in history. To compare and rank the EVV …		 ALHASSANE DIALLO et. al. Human vaccines & immunotherapeutics 2021-07-16
504 Mapping The Global Research Output on Ebola Vaccine from Research Indexed in Web of Science and Scopus: A Comprehensive Bibliometric Analysis
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Abstract: : The Ebola Virus outbreak in Africa is believed to be one of the deadliest viral infections that causes severe hemorrhagic fever in human and nonhuman primates, which has …		 TOSIN YINKA AKINTUNDE et. al. Human vaccines & immunotherapeutics 2021-07-16
505 A Snapshot of Poverty, Diseases and War – The Democratic Republic of The Congo
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Abstract: DRC’s fight with the EVD (Ebola Virus Disease) was just settling when WHO declared COVID-19 to be a Public Health Emergency of International Concern (PHEIC) on March 12, 2020. …		 Shibu Sasidharan; Harpreet Singh Dhillon; Disaster medicine and public health preparedness 2021-07-15
506 Immunopathogenesis of Different Emerging Viral Infections: Evasion, Fatal Mechanism, and Prevention
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Abstract: Different emerging viral infections may emerge in different regions of the world and pose a global pandemic threat with high fatality. Clarification of the immunopathogenesis of …		 Betsy Yang; Kuender D Yang; Frontiers in immunology 2021-07-15
507 Health Seeking Behavior After The 2013-16 Ebola Epidemic: Lassa Fever As A Metric of Persistent Changes in Kenema District, Sierra Leone
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Abstract: The West African Ebola epidemic of 2013-2016 killed nearly 4,000 Sierra Leoneans and devastated health infrastructure across West Africa. Changes in health seeking behavior (HSB) …		 MIKAELA R KOCH et. al. PLoS neglected tropical diseases 2021-07-14
508 Ebola As A Case Study for The Patent Landscape of Medical Countermeasures for Emerging Infectious Diseases
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 Nasir Mohajel; Arash Arashkia; Nature biotechnology 2021-07-14
509 Motivators of Continued Participation in Public Health Emergency Response Among Federal Public Health Workers: A Qualitative Study
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Abstract: The purpose of this study was to identify factors that motivate public health workers to deploy to the field during an emergency event. We conducted 25 semistructured interviews …		 Shawn C Chiang; Holly H Fisher; Matthew E Bridwell; Bobby B Rasulnia; Sachiko A Kuwabara; Health security 2021-07-13
510 Structural Insight Into Marburg Virus Nucleoprotein-RNA Complex Formation
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Highlight: Here, we show the structure of the MARV NP-RNA complex determined using cryo-electron microscopy at a resolution of 3.1 angstrom.		 Y. FUJITA-FUJIHARU et. al. bio.microbiology 2021-07-13
511 Development and Evaluation of An Ebola Virus Glycoprotein Mucin-Like Domain Replacement System As A New Dendritic Cell-Targeting Vaccine Approach Against HIV-1
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Abstract: The development of efficient vaccine approaches against HIV infection remains challenging in the vaccine field. Here, we developed an Ebola virus envelope glycoprotein …		 ZHUJUN AO et. al. Journal of virology 2021-07-12
512 Therapeutic Antibodies Under Development for SARS-CoV-2
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Abstract: The world is experiencing one of the most difficult moments in history with COVID-19, which has rapidly developed into a worldwide pandemic with a significant health and economic …		 ZETONG MA et. al. View (Beijing, China) 2021-07-12
513 Why Remdesivir Failed: Preclinical Assumptions Overestimate The Clinical Efficacy of Remdesivir for COVID-19 and Ebola
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Abstract: Remdesivir is a nucleoside monophosphoramidate prodrug that has been FDA approved for coronavirus disease 2019 (COVID-19). However, the clinical efficacy of remdesivir for …		 Victoria C Yan; Florian L Muller; Antimicrobial agents and chemotherapy 2021-07-12
514 Factors Associated with Length of Stay and Treatment Outcome of Ebola Patients Treated at An Ebola Treatment Center in Sierra Leone During The Peak Period of The West African Ebola Outbreak 2013-2016
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Abstract: The World Health Organization (WHO) declared the West Africa Ebola epidemic as a Public Health Emergency of International Concern in August 2014. During the outbreak period, there …		 Jia Bainga Kangbai; Christian Heumann; Michael Hoelscher; Foday Sahr; Guenter Froeschl; Archives of public health = Archives belges de sante … 2021-07-12
515 Religion, Social Connectedness, and Xenophobic Responses to Ebola
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Abstract: This study examined the role of religion in xenophobic responses to the threat of Ebola. Religious communities often offer members strong social ties and social support, which may …		 Roxie Chuang; Kimin Eom; Heejung S Kim; Frontiers in psychology 2021-07-12
516 A Call to Safeguard Sexual and Reproductive Health Information and Services During Ebola Outbreaks
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Abstract: The recent Ebola virus disease (EVD) outbreaks in 2021 exemplify how sexual and reproductive health services are too often considered unessential during health emergencies. …		 Nguyen Toan Tran; Désirée Lichtenstein; Benjamin Black; Alice Rosmini; Catrin Schulte-Hillen; Conflict and health 2021-07-10
517 What Factors Promote Vaccine Hesitancy or Acceptance During Pandemics? A Systematic Review and Thematic Analysis
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Abstract: Examine the factors that promote vaccine hesitancy or acceptance during pandemics, major epidemics and global outbreaks. A systematic review and thematic analysis of 28 studies on …		 Judy Truong; Simran Bakshi; Aghna Wasim; Mobeen Ahmad; Umair Majid; Health promotion international 2021-07-10
518 Knowledge, Perceptions and Effects of Ebola Virus Disease Outbreak on The Pig Value Chain in The Agro-pastoralist District of Luwero, Central Uganda
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Abstract: Ebola Virus Disease (EVD) outbreaks have a significant impact on the health and wellbeing, and livelihoods of communities. EVD response interventions particularly affect the food …		 DOREEN BIRUNGI et. al. BMC infectious diseases 2021-07-09
519 The East African Community (EAC) Mobile Laboratory Networks in Kenya, Burundi, Tanzania, Rwanda, Uganda, and South Sudan-from Project Implementation to Outbreak Response Against Dengue, Ebola, COVID-19, and Epidemic-prone Diseases
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Abstract: East Africa is home to 170 million people and prone to frequent outbreaks of viral haemorrhagic fevers and various bacterial diseases. A major challenge is that epidemics mostly …		 MUNA AFFARA et. al. BMC medicine 2021-07-09
520 ‘I Can’t Leave Everything in The Hands of My Husband’: Economic Constraints and Gender Roles in Care-seeking in Post-Ebola Guinea
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Abstract: The 2014-2016 Ebola epidemic in West Africa had enduring effects on health systems and healthcare utilisation. This study explores the intersection of economic constraints and …		 ZOÉ MISTRALE HENDRICKSON et. al. Global public health 2021-07-09
521 From Ebola to COVID-19: Emergency Preparedness and Response Plans and Actions in Lagos, Nigeria
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Abstract: Lagos state is the industrial nerve centre of Nigeria and was the epicentre of the 2014 Ebola outbreak in Nigeria as it is now for the current Coronavirus Disease (COVID-19) …		 AKIN ABAYOMI et. al. Globalization and health 2021-07-09
522 Implementation of The Ebola Virus Persistence in Ocular Tissues and Fluids (EVICT) Study: Lessons Learned for Vision Health Systems Strengthening in Sierra Leone
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Abstract: Following the West African Ebola virus disease (EVD) outbreak of 2013-2016 and more recent EVD outbreaks in the Democratic Republic of Congo, thousands of EVD survivors are …		 JESSICA G SHANTHA et. al. PloS one 2021-07-09
523 PTSD, Depression and Anxiety in Ebola Virus Disease Survivors in Beni Town, Democratic Republic of The Congo
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Abstract: Ebola Virus Disease (EVD) is a deadly and feared infectious disease, which can be responsible of debilitating physical and psychological sequelae in survivors including depression …		 Célestin Kaputu-Kalala-Malu;