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Paper Digest: Recent Papers on Ebola Virus Disease

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To help researchers quickly catch up the most recent work in health science, Paper Digest Team extracted all recent Ebola Virus Disease related papers on our radar, and list them in this article. This article will be updated on a daily basis to reflect new progresses in this area. (Last updated on: 2022-01-23) Based in New York, Paper Digest is dedicated to producing high-quality text analysis results that people can acturally use on a daily basis. In the past 4 years, we have been serving users across the world with a number of exclusive services on ranking, search, tracking and review. This month we feature Literature Review Generator, which automatically generates literature review around any topic.

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TABLE 1: Paper Digest: Recent Papers on Ebola Virus Disease

Paper Author(s) Source Date
1 The Ring Vaccination Trial Design for The Estimation of Vaccine Efficacy and Effectiveness During Infectious Disease Outbreaks
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Abstract: The ring vaccination trial is a recently developed approach for evaluating the efficacy and effectiveness of vaccines, modeled after the surveillance and containment strategy of …		 Natalie E Dean; Ira M Longini; Clinical trials (London, England) 2022-01-21
2 Association Between Oral Antimalarial Medication Administration and Mortality Among Patients with Ebola Virus Disease: A Multisite Cohort Study
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Abstract: Empiric antimalarial treatment is a component of protocol-based management of Ebola virus disease (EVD), yet this approach has limited clinical evidence for patient-centered …		 LOGAN ABEL et. al. BMC infectious diseases 2022-01-20
3 From Viral Evolution to Spatial Contagion: A Biologically Modulated Hawkes Model
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Abstract: Mutations sometimes increase contagiousness for evolving pathogens. During an epidemic, scientists use viral genome data to infer a shared evolutionary history and connect this …		 Andrew J Holbrook; Xiang Ji; Marc A Suchard; Bioinformatics (Oxford, England) 2022-01-18
4 Selective Estrogen Receptor Modulators Limit Alphavirus Infection By Targeting The Viral Capping Enzyme NsP1
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Abstract: Alphaviruses cause animal or human diseases that are characterized by febrile illness, debilitating arthralgia, or encephalitis. Selective estrogen receptor modulators (SERMs), a …		 RAJAT MUDGAL et. al. Antimicrobial agents and chemotherapy 2022-01-18
5 The Role of Phosphatidylserine on The Membrane in Immunity and Blood Coagulation
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Abstract: The negatively charged aminophospholipid, phosphatidylserine (PtdSer), is located in the inner leaflet of the plasma membrane in normal cells, and may be exposed to the outer …		 JIAO WANG et. al. Biomarker research 2022-01-15
6 Health-related Quality of Life Among Ebola Survivors in Sierra Leone: The Role of Socio-demographic, Health-related and Psycho-social Factors
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Abstract: Evidence of how social factors affect the health-related quality of life (HRQoL) of Ebola virus disease (EVD) survivors is limited. Our study explores the association between …		 PETER BAI JAMES et. al. Health and quality of life outcomes 2022-01-15
7 Pandemic Inequalities: Emerging Infectious Diseases and Health Equity
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Abstract: The frequency and scale of Emerging Infectious Diseases (EIDs) with pandemic potential has been increasing over the last two decades and, as COVID-19 has shown, such zoonotic …		 Clare Bambra; International journal for equity in health 2022-01-14
8 In Vivo Single-cell Profiling of LncRNAs During Ebola Virus Infection
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Highlight: This study provides novel insights into the roles that lncRNAs play in the host response to acute viral infection and paves the way for future lncRNA studies at single-cell resolution.		 L. SANTUS et. al. bio.genomics 2022-01-13
9 Ebola Virus GP Activates Endothelial Cells Via Host Cytoskeletal Signaling Factors
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Abstract: Ebola virus disease (EVD) is a lethal disease caused by the highly pathogenic Ebola virus (EBOV), and its major symptoms in severe cases include vascular leakage and hemorrhage. …		 Benedicte Mpia Moni; Yasuteru Sakurai; Jiro Yasuda; Viruses 2022-01-13
10 Best Practices of Highly Infectious Decedent Management: Consensus Recommendations from An International Expert Workshop
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Abstract: With the increasing number of highly infectious disease incidents, outbreaks, and pandemics in our society (e.g., Ebola virus disease, Lassa fever, coronavirus diseases), the need …		 AURORA B LE et. al. Journal of occupational and environmental hygiene 2022-01-13
11 Ebola Virus Disease and Current Therapeutic Strategies: A Review
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Abstract: The Ebola virus disease is a severe hemorrhagic fever that affects humans and other primates. Ebola virus, the causative agent of the disease, is transmitted to humans from wild …		 KALLIOPI IO DIAKOU et. al. Advances in experimental medicine and biology 2022-01-13
12 Quantitative Analysis of Genomic Sequences of Virus RNAs Using A Metric-Based Algorithm
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Highlight: This work aims to study the virus RNAs using a novel accelerated algorithm on exploring any-length genomic fragments in sequences using Hamming distance between the binary-expressed RNA symbols and explored pattern characters.		 A. Belinsky; G. Kouzaev; bio.genomics 2022-01-12
13 Selective Estrogen Receptor Modulators Limit Alphavirus Infection By Targeting The Viral Capping Enzyme NsP1
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Highlight: Combining biochemical, cell culture-based studies, and in vivo analyses, we strongly argue that SERM compounds, or their derivatives, may provide for attractive therapeutic options against alphaviruses.		 R. MUDGAL et. al. bio.immunology 2022-01-12
14 Rapid Protection from COVID-19 in Nonhuman Primates Vaccinated Intramuscularly But Not Intranasally with A Single Dose of A Vesicular Stomatitis Virus-Based Vaccine
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Abstract: The ongoing pandemic of coronavirus (CoV) disease 2019 (COVID-19) continues to exert a significant burden on health care systems worldwide. With limited treatments available, …		 WAKAKO FURUYAMA et. al. mBio 2022-01-11
15 Immune Interference Revisited: Impact of Live-attenuated Influenza Vaccine Prior to Yellow Fever Vaccination
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Abstract: During routine mass live-attenuated influenza vaccination (LAIV) for military personnel, emergent deployment for Ebola humanitarian assistance (OUA) required mass yellow fever …		 Dana M Blyth; Zhaodong Liang; Maya Williams; Clinton K Murray; Vaccine 2022-01-11
16 Safety and Immunogenicity of 2-dose Heterologous Ad26.ZEBOV, MVA-BN-Filo Ebola Vaccination in Children and Adolescents in Africa: A Randomised, Placebo-controlled, Multicentre Phase II Clinical Trial
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Abstract: Reoccurring Ebola outbreaks in West and Central Africa have led to serious illness and death in thousands of adults and children. The objective of this study was to assess safety, …		 ZACCHAEUS ANYWAINE et. al. PLoS medicine 2022-01-11
17 Prevalence and Risk Factors of Depression Symptoms Among Rural and Urban Populations Affected By Ebola Virus Disease in The Democratic Republic of The Congo: A Representative Cross-sectional Study
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Abstract: High mortality rates, anxiety and distress associated with Ebola virus disease (EVD) are risk factors for mood disorders in affected communities. This study aims to document the …		 JUDE MARY CÉNAT et. al. BMJ open 2022-01-11
18 Synthesis and Biological Application of Glyco- and Peptide Derivatives of Fullerene C 60
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Abstract: Fullerenes have attracted considerable attention for their possible use in human therapy. Pure C is soluble only in some organic solvents, but this could be overcome by chemical …		 Lisa Tanzi; Marco Terreni; Yongmin Zhang; European journal of medicinal chemistry 2022-01-10
19 Author Correction: Cryo-EM Structure of The Ebola Virus Nucleoprotein-RNA Complex at 3.6 Å Resolution
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 Yukihiko Sugita; Hideyuki Matsunami; Yoshihiro Kawaoka; Takeshi Noda; Matthias Wolf; Nature 2022-01-07
20 Comparative Greenness Metric Estimates for Content Uniformity Testing of Anti-Cov-2, GS-5734 in Commercial Vials; Validated Micellar Electrokinetic Chromatographic Assay
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Abstract: The antiviral drug GS-5734 Remdesivir is a new phosphoramidate prodrug developed initially as treatment for Ebola virus and then proved to have antiviral properties against …		 Sohila M Elonsy; Miranda F Kamal; Mohamed M A Hamdy; Mona M Abdel Moneim; Journal of AOAC International 2022-01-07
21 Therapeutic Spectrum of Piperine for Clinical Practice: A Scoping Review
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Abstract: Translation of traditional knowledge of herbs into a viable product for clinical use is still an uphill task. Piperine, a pungent alkaloid molecule derived from and possesses …		 SURAJ S YADAV et. al. Critical reviews in food science and nutrition 2022-01-07
22 Synthetic Nanobody-functionalized Nanoparticles for Accelerated Development of Rapid, Accessible Detection of Viral Antigens
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Abstract: Successful control of emerging infectious diseases requires accelerated development of fast, affordable, and accessible assays for wide implementation at a high frequency. This …		 XIAHUI CHEN et. al. Biosensors & bioelectronics 2022-01-06
23 Scientometric Analysis of Public Health Emergencies: 1994-2020
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Abstract: The purpose of this paper is to summarize the research hotspots and frontiers in the field of public health emergencies (PHE) between 1994-2020 through the scientometric analysis …		 Jing Liu; Yujie Wang; Qian Zhang; Jianxiang Wei; Haihua Zhou; International journal of environmental research and public … 2022-01-06
24 More Than A Gender Issue: Testis As A Distinctive HIV Reservoir and Its Implication for Viral Eradication
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Abstract: Early establishment of HIV reservoir represents the main impediment to an HIV cure. Mainly composed of infected memory CD4 T-cells and macrophages, HIV reservoirs are found in …		 Jean-Pierre Routy; Franck P Dupuy; John Lin; Stéphane Isnard; Methods in molecular biology (Clifton, N.J.) 2022-01-05
25 [Remdesivir for COVID-19]
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Abstract: Remdesivir is a direct-acting antiviral agent that inhibits viral RNA synthesis developed by Gilead Sciences, Inc. in the United States. It has been shown to have antiviral …		 Yasuhisa Fujita; Nihon yakurigaku zasshi. Folia pharmacologica Japonica 2022-01-04
26 Ebola Virus Disease: Current Perception of Clinical Features, Diagnosis, Pathogenesis, and Therapeutics
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Abstract: Zoonotic transmission of highly pathogenic viruses, are a cause of deadly epidemics around the globe. These are of particular concern as evident from the recent global pandemic …		 Ruqaiyyah Siddiqui; Simal Khan; Naveed Ahmed Khan; Acta virologica 2022-01-03
27 A Protocol for A Scoping Review Comparative Bibliometric Analysis of Infectious Disease Research in Africa
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Abstract: Evidence on authorship trends of health research conducted about or in Africa shows that there is a lack of local researchers in the first and last authorship positions, with high …		 Adrianna Perryman; Gebremedhin Beedemariam Gebretekle; Adeteju Ogunbameru; Joanna M Bielecki; Beate Sander; Frontiers in public health 2022-01-03
28 HIV-1 Trans -Infection Mediated By DCs: The Tip of The Iceberg of Cell-to-Cell Viral Transmission
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Abstract: HIV-1 cell-to-cell transmission is key for an effective viral replication that evades immunity. This highly infectious mechanism is orchestrated by different cellular targets that …		 DANIEL PEREZ-ZSOLT et. al. Pathogens (Basel, Switzerland) 2021-12-31
29 Natural History of Nonhuman Primates After Conjunctival Exposure to Ebola Virus
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Highlight: Historically, nonhuman primate (NHP) challenge studies have employed intramuscular or small particle aerosol exposure, which are uniformly lethal routes of infection, but mimic worst-case scenarios such as a needlestick.		 R. W. CROSS et. al. bio.microbiology 2021-12-30
30 Graphene-based Nanomaterials in Fighting The Most Challenging Viruses and Immunogenic Disorders
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Abstract: Viral diseases have long been among the biggest challenges for healthcare systems around the world. The recent Coronavirus Disease 2019 (COVID-19) pandemic is an example of how …		 Mahsa Ebrahimi; Mohamad Asadi; Omid Akhavan; ACS biomaterials science & engineering 2021-12-30
31 The Deuce-ace of Lassa Fever, Ebola Virus Disease and COVID-19 Simultaneous Infections and Epidemics in West Africa: Clinical and Public Health Implications
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Abstract: Globally, the prevailing COVID-19 pandemic has caused unprecedented clinical and public health concerns with increasing morbidity and mortality. Unfortunately, the burden of …		 NNABUEZE DARLINGTON NNAJI et. al. Tropical medicine and health 2021-12-30
32 S-palmitoylation and Sterol Interactions Mediate Antiviral Specificity of IFITM Isoforms
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Abstract: Interferon-induced transmembrane proteins (IFITM1, 2 and 3) are important antiviral proteins that are active against many viruses, including influenza A virus (IAV), dengue virus …		 TANDRILA DAS et. al. Research square 2021-12-29
33 Functional Interactomes of The Ebola Virus Polymerase Identified By Proximity Proteomics in The Context of Viral Replication
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Highlight: Here we leveraged proximity proteomics and conducted an siRNA screen to define the functional interactome of EBOV polymerase.		 J. FANG et. al. bio.microbiology 2021-12-28
34 The Discovery and Development of Novel Treatment Strategies for Filoviruses
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Abstract: Filoviruses are negative-stranded, enveloped RNA viruses that can cause hemorrhagic fever in humans and include Ebola and Marburg viruses. Lethality rates can reach 90% in …		 Steven B Bradfute; Expert opinion on drug discovery 2021-12-28
35 TRIPS to Where? A Narrative Review of The Empirical Literature on Intellectual Property Licensing Models to Promote Global Diffusion of Essential Medicines
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Abstract: Governed through the World Trade Organization Agreement on Trade-Related Aspects of Intellectual Property Rights (TRIPS) since 1995, the current medical R&D system requires …		 Shiri Mermelstein; Hilde Stevens; Pharmaceutics 2021-12-27
36 Rapid and Durable Protection Against Marburg Virus with A Single-Shot ChAd3-MARV GP Vaccine
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Highlight: To support regulatory approval of the ChAd3-Marburg vaccine that has completed Phase I trials, we show that a non-replicating chimpanzee-derived adenovirus vector with a demonstrated safety profile in humans (ChAd3) protected against a uniformly lethal challenge with Marburg-Angola.		 R. HUNEGNAW et. al. bio.immunology 2021-12-25
37 Extending Upon: What Effect Might Border Screening Have on Preventing Importation of COVID-19 Compared with Other Infections? – Considering The Additional Effect of Post-arrival Isolation
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Highlight: We recently described a simple model through which we assessed what effect subjecting travellers to a single on-arrival test might have on reducing risk of importing disease cases during simulated outbreaks of COVID-19, Influenza, SARS, and Ebola.		 D. Bays; E. Bennett; T. J. R. Finnie; med.public-and-global-health 2021-12-25
38 Implications of RNA Viruses in The Male Reproductive Tract: An Outlook on SARS-CoV-2
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Abstract: Emerging viral infections continuously pose a threat to human wellbeing. Several RNA viruses have managed to establish access to the male reproductive tract and persist in human …		 Mohammad Ishraq Zafar; Jiangyu Yu; Honggang Li; Frontiers in microbiology 2021-12-24
39 Potential Benefits of Antiviral African Medicinal Plants in The Management of Viral Infections: Systematic Review
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Abstract: Viruses cause various human diseases, some of which become pandemic outbreaks. This study synthesized evidence on antiviral medicinal plants in Africa which could potentially be …		 TAMIRAT BEKELE BERESSA et. al. Frontiers in pharmacology 2021-12-24
40 Multipurpose Drugs Active Against Both Plasmodium Spp. and Microorganisms: Potential Application for New Drug Development
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Abstract: Malaria, a disease caused by the protozoan parasites spp., is still causing serious problems in endemic regions in the world. Although the WHO recommends artemisinin combination …		 Takuro Endo; Hitoshi Takemae; Indu Sharma; Tetsuya Furuya; Frontiers in cellular and infection microbiology 2021-12-24
41 Mechanisms of Phosphatidylserine Influence on Viral Production: A Computational Model of Ebola Virus Matrix Protein Assembly
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Highlight: Here we used a computational model to evaluate EBOV matrix assembly.		 X. LIU et. al. bio.systems-biology 2021-12-23
42 Activity of Galidesivir in A Hamster Model of SARS-CoV-2
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Abstract: Coronavirus disease 2019 (COVID-19) has claimed the lives of millions of people worldwide since it first emerged. The impact of the COVID-19 pandemic on public health and the …		 RAY TAYLOR et. al. Viruses 2021-12-21
43 Pharmacologically Induced Endolysosomal Cholesterol Imbalance Through Clinically Licensed Drugs Itraconazole and Fluoxetine Impairs Ebola Virus Infection in Vitro
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Abstract: Ebola virus disease (EVD) is a severe and frequently lethal disease caused by Ebola virus (EBOV). The latest occasional EVD outbreak (2013-2016) in Western African, which was …		 SUSANN KUMMER et. al. Emerging microbes & infections 2021-12-17
44 CD47 Expression Attenuates Ebola Virus-induced Immunopathology in Mice
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Abstract: It has been shown that a very early cell-intrinsic response to infection is the upregulation of CD47 cell surface expression, a molecule known for delivering a don’t eat me …		 DEEPASHRI RAO et. al. Antiviral research 2021-12-17
45 Heterologous Prime-boost Strategies for COVID-19 Vaccines
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Abstract: Heterologous prime-boost doses of COVID-19 vaccines (‘mix-and-match’ approach) are being studied to test for the effectiveness of Oxford (AZD1222), Pfizer (BNT162b2), Moderna …		 BINAYA SAPKOTA et. al. Journal of travel medicine 2021-12-16
46 Cryo-EM Analysis of Ebola Virus Nucleocapsid-like Assembly
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Abstract: This protocol describes the reconstitution of the filamentous Ebola virus nucleocapsid-like assembly . This is followed by solving the cryo-EM structure using helical …		 YAN WANG et. al. STAR protocols 2021-12-16
47 Design of Replication-Competent VSV- and Ervebo-Vectored Vaccines Against SARS-CoV-2
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Abstract: Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a global public health emergency. Several vaccine candidates have …		 Qixing Liu; Zhe Ding; Jiaming Lan; Gary Wong; Methods in molecular biology (Clifton, N.J.) 2021-12-16
48 Development and Characterization of Recombinant Vesicular Stomatitis Virus (rVSV)-based Bivalent Vaccine Against COVID-19 Delta Variant and Influenza Virus
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Highlight: In this study, we generated three attenuated replicating recombinant VSV (rVSV) vaccine candidates.		 Z. AO et. al. bio.microbiology 2021-12-15
49 InterARTIC: An Interactive Web Application for Whole-genome Nanopore Sequencing Analysis of SARS-CoV-2 and Other Viruses
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Abstract: InterARTIC is an interactive web application for the analysis of viral whole-genome sequencing (WGS) data generated on Oxford Nanopore Technologies (ONT) devices. A graphical …		 JAMES M FERGUSON et. al. Bioinformatics (Oxford, England) 2021-12-15
50 Heptad Stereotypy, S/Q Layering, and Remote Origin of The SARS-CoV-2 Fusion Core
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Abstract: The fusion of the SARS-CoV-2 virus with cells, a key event in the pathogenesis of Covid-19, depends on the assembly of a six-helix fusion core (FC) formed by portions of the spike …		 CHIARA MARCHETTI et. al. Virus evolution 2021-12-15
51 A Live-attenuated Viral Vector Vaccine Protects Mice Against Lethal Challenge with Kyasanur Forest Disease Virus
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Abstract: Kyasanur Forest disease virus (KFDV) is a tick-borne flavivirus endemic in India known to cause severe hemorrhagic and encephalitic disease in humans. In recent years, KFDV has …		 BHARTI BHATIA et. al. NPJ vaccines 2021-12-14
52 Enhancing The Antiviral Potency of Nucleobases for Potential Broad-Spectrum Antiviral Therapies
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Abstract: Broad-spectrum antiviral therapies hold promise as a first-line defense against emerging viruses by blunting illness severity and spread until vaccines and virus-specific …		 RUBEN SOTO-ACOSTA et. al. Viruses 2021-12-14
53 Developing A Secretory AcGFP1-based IRES Expression System for Efficient Production of Mammalian Recombinant Proteins
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Abstract: To generate stable cell lines that express high levels of recombinant genes often requires screening of a large number of transfected cells using ELISA. The most widely used …		 Zhongcheng Zou; Matthew Spencer; Peter D Sun; Protein expression and purification 2021-12-14
54 Identification of Novel Ebola Virus Inhibitors Using Biologically Contained Virus
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Highlight: In this study, we used biologically contained Ebola virus to screen over 4,200 small-molecule drugs and drug-like compounds provided by the Medicines for Malaria Venture (i.e., the Pandemic Response Box and the COVID Box) and the Centre for Drug Design and Discovery (CD3, KU Leuven, Belgium).		 B. VANMECHELEN et. al. bio.microbiology 2021-12-12
55 The 2018-2020 Ebola Outbreak in The Democratic Republic of Congo: A Better Response Had Been Achieved Through Inter-State Coordination in Africa
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Abstract: The Ebola virus disease, formerly known as Ebola hemorrhagic fever, is a severe and often fatal zoonosis in humans. The 2013-2016 West African Ebola outbreak had distinctive …		 RAOUL EMERIC GUETIYA WADOUM et. al. Risk management and healthcare policy 2021-12-10
56 Current State of Ebola Virus Vaccines: A Snapshot
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 Courtney Woolsey; Thomas W Geisbert; PLoS pathogens 2021-12-09
57 Can Major Public Health Emergencies Affect Changes in International Oil Prices?
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Abstract: In order to deepen the understanding of the impact of major public health emergencies on the oil market and to enhance the risk response capability, this study analyzed the …		 An Cheng; Tonghui Chen; Guogang Jiang; Xinru Han; International journal of environmental research and public … 2021-12-08
58 Marburg and Ebola Virus Infections Elicit A Complex, Muted Inflammatory State in Bats
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Highlight: In this study, we outline multiple interconnected pathways that respond to infection by MARV and EBOV, providing insights into the complexity of the mechanisms that enable bats to resist the disease caused by filoviral infections.		 A. D. JAYAPRAKASH et. al. bio.microbiology 2021-12-08
59 Marburg Virus Disease Outbreak Amidst COVID-19 in The Republic of Guinea: A Point of Contention for The Fragile Health System?
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Abstract: In August 2021, the Marburg virus disease (MVD) outbreak was confirmed amid the coronavirus disease 2019 (COVID-19) pandemic in the Republic of Guinea. This is the first time it …		 OSARETIN CHRISTABEL OKONJI et. al. Clinical epidemiology and global health 2021-12-08
60 Ebola Virus Disease Nosocomial Infections in The Democratic Republic of The Congo: A Descriptive Study of Cases During The 2018-2020 Outbreak
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Abstract: To describe the characteristics of nosocomial cases of Ebola virus disease (EVD) in the Democratic Republic of the Congo between July 2018 and May 2020 in order to inform future …		 APRIL BALLER et. al. International journal of infectious diseases : IJID : … 2021-12-07
61 Economic Evaluation Using Dynamic Transition Modeling of Ebola Virus Vaccination in Lower-and-middle-income Countries
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Abstract: With the increasing occurrence of infectious diseases in lower-and-middle-income countries (LMICs), emergency preparedness is essential for rapid response and mitigation. Economic …		 Mavis Obeng-Kusi; Magdiel A Habila; Denise J Roe; Brian Erstad; Ivo Abraham; Journal of medical economics 2021-12-06
62 Rhesus Macaque CODEX Multiplexed Immunohistochemistry Panel for Studying Immune Responses During Ebola Infection
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Abstract: Non-human primate (NHP) animal models are an integral part of the drug research and development process. For some biothreat pathogens, animal model challenge studies may offer the …		 SIZUN JIANG et. al. Frontiers in immunology 2021-12-06
63 A Review of Infectious Diseases Associated with Religious and Nonreligious Rituals
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Abstract: Rituals are an integral part of human life but a wide range of rituals (both religious and non-religious), from self-flagellation to blood brotherhood to ritual sprinkling of holy …		 Kiran Gajurel; Stan Deresinski; Interdisciplinary perspectives on infectious diseases 2021-12-06
64 Quantification of Type I Interferon Inhibition By Viral Proteins: Ebola Virus As A Case Study
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Abstract: Type I interferons (IFNs) are cytokines with both antiviral properties and protective roles in innate immune responses to viral infection. They induce an antiviral cellular state …		 MACAULEY LOCKE et. al. Viruses 2021-12-04
65 Rapid Establishment of A Frontline Field Laboratory in Response to An Imported Outbreak of Ebola Virus Disease in Western Uganda, June 2019
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Abstract: The Democratic Republic of the Congo (DRC) declared an Ebola virus disease (EVD) outbreak in North Kivu in August 2018. By June 2019, the outbreak had spread to 26 health zones in …		 AMY J SCHUH et. al. PLoS neglected tropical diseases 2021-12-03
66 Ebola Virus Disease in Pregnancy: A Systematic Review and Meta-analysis
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Abstract: This review synthesises and appraises evidence on the effects of Ebola virus disease (EVD) in pregnancy. We searched bibliographic databases from dates of inception to November …		 NZELLE D KAYEM et. al. Transactions of the Royal Society of Tropical Medicine and … 2021-12-02
67 Editorial Overview: An Initiative Toward Ebolavirus Disease (EVD) Free World: An Edited Special Anti-infective Issue on Ebola Virus Disease
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 Elijah I Ohimain; Chiranjib Chakraborty; Current opinion in pharmacology 2021-12-02
68 Computational Study on Potential Novel Anti-Ebola Virus Protein VP35 Natural Compounds
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Abstract: Ebola virus (EBOV) is one of the most lethal pathogens that can infect humans. The Ebola viral protein VP35 (EBOV VP35) inhibits host IFN-α/β production by interfering with host …		 LOUIS K S DARKO et. al. Biomedicines 2021-11-30
69 A Reliable Solution of Nonlinear Time Dependent Fractional Model of Ebola Virus Disease with Arbitrary Order Derivative in Liouville-Caputo Sense
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Abstract: In this article, the analysis of an arbitrary order Ebola virus disease model is conducted to find out its reliable solution. The fractional derivative is taken in …		 Vinod Kumar Bhardwaj; Manish Goyal; International journal of applied and computational … 2021-11-30
70 Pacing Forward in The Face of Fragility: Lessons From African Institutions and Governments’ Response to Public Health Emergencies
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Abstract: Africa is home to 54 United Nation member states, each possessing a wealth of ethno-cultural, physiographic, and economic diversity. While Africa is credited as having the …		 Byron Bitanihirwe; Derrick Ssewanyana; Ismael Ddumba-Nyanzi; Frontiers in public health 2021-11-25
71 The Power of Music to Prevent and Control Emerging Infectious Diseases
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Abstract: Music is a powerful approach to engage communities and disseminate information. Specifically, health campaigns employing music have been used to promote behaviors that can prevent …		 JULIO A BENAVIDES et. al. Frontiers in medicine 2021-11-25
72 Broad-Spectrum In Vitro Antiviral Activity of ODBG-P-RVn: An Orally-Available, Lipid-Modified Monophosphate Prodrug of Remdesivir Parent Nucleoside (GS-441524)
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Abstract: The necessity for intravenous administration of remdesivir confines its utility for treatment of coronavirus disease 2019 (COVID-19) to hospitalized patients. We evaluated the …		 MICHAEL K LO et. al. Microbiology spectrum 2021-11-24
73 Gaps and Opportunities in HIV Service Delivery in High Volume HIV Care Centers in Liberia: Lessons From The Field
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Abstract: Human Immunodeficiency Virus (HIV) infection continues to have a profound humanitarian and public health impact in western and central Africa, a region that risks being left …		 MUKHTAR A ADEIZA et. al. Annals of global health 2021-11-24
74 The Ebola Crisis and People with Disabilities’ Access to Healthcare and Government Services in Liberia
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Abstract: There has been little research on the impact of the 2014-2015 West African Ebola crisis on people with disabilities. This paper outlines the way in which the Ebola Virus Disease …		 MARIA KETT et. al. International journal for equity in health 2021-11-24
75 LazySampling and LinearSampling: Fast Stochastic Sampling of RNA Secondary Structure with Applications to SARS-CoV-2
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Abstract: Many RNAs fold into multiple structures at equilibrium. The classical stochastic sampling algorithm can sample secondary structures according to their probabilities in the …		 He Zhang; Liang Zhang; Sizhen Li; David H Mathews; Liang Huang; bioRxiv : the preprint server for biology 2021-11-24
76 LazySampling and LinearSampling: Fast Stochastic Sampling of RNA Secondary Structure with Applications to SARS-CoV-2
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Highlight: Based on LazySampling, we further replace the cubic-time partition function by a linear-time approximate one, and derive LinearSampling, an end-to-end linear-time sampling algorithm that is orders of magnitude faster than the standard one.		 H. Zhang; L. Zhang; S. Li; D. Mathews; L. Huang; bio.bioinformatics 2021-11-24
77 Behaviours of Antiviral Oseltamivir in Different Media: DFT and SQMFF Calculations
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Abstract: The synthetic cyclohexenecarboxylate ester antiviral Oseltamivir (O) have been theoretically studied by B3LYP/6-311 +  + G** calculations to estimate its reactivity and behaviour …		 Mohammad Vakili; Elida Romano; Vahidreza Darugar; Silvia Antonia Brandán; Journal of molecular modeling 2021-11-23
78 Data Science Approaches to Infectious Disease Surveillance
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Abstract: Novel data science approaches are needed to confront large-scale infectious disease epidemics such as COVID-19, human immunodeficiency viruses, African swine flu and Ebola. Human …		 Qingpeng Zhang; Philosophical transactions. Series A, Mathematical, … 2021-11-22
79 Novel Use of Capture-Recapture Methods to Estimate Completeness of Contact Tracing During An Ebola Outbreak, Democratic Republic of The Congo, 2018-2020
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Abstract: Despite its critical role in containing outbreaks, the efficacy of contact tracing, measured as the sensitivity of case detection, remains an elusive metric. We estimated the …		 JONATHAN A POLONSKY et. al. Emerging infectious diseases 2021-11-22
80 Evaluation of Early Warning, Alert and Response System for Ebola Virus Disease, Democratic Republic of The Congo, 2018-2020
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Abstract: The 10th and largest Ebola virus disease epidemic in the Democratic Republic of the Congo (DRC) was declared in North Kivu Province in August 2018 and ended in June 2020. We …		 MORY KEITA et. al. Emerging infectious diseases 2021-11-22
81 Andrographolide: A Herbal-Chemosynthetic Approach for Enhancing Immunity, Combating Viral Infections, and Its Implication on Human Health
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Abstract: Plants consistently synthesize and accumulate medically valuable secondary metabolites which can be isolated and clinically tested under in vitro conditions. An advancement with …		 Archana Mishra; Haq Abdul Shaik; Rakesh Kumar Sinha; Bakht Ramin Shah; Molecules (Basel, Switzerland) 2021-11-21
82 Cross-Reactive Antibodies to SARS-CoV-2 and MERS-CoV in Pre-COVID-19 Blood Samples from Sierra Leoneans
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Abstract: Many countries in sub-Saharan Africa have experienced lower COVID-19 caseloads and fewer deaths than countries in other regions worldwide. Under-reporting of cases and a younger …		 RODRIGO BORREGA et. al. Viruses 2021-11-21
83 WWOX-Mediated Degradation of AMOTp130 Negatively Affects Egress of Filovirus VP40 VLPs
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Highlight: In this report, we demonstrate that host WWOX, which negatively regulates egress of VP40 VLPs and recombinant VSV-M40 virus, interacts with and suppresses the expression of AMOT.		 J. Liang; G. Ruthel; B. Freedman; R. N. Harty; bio.microbiology 2021-11-20
84 Gender-based Violence and Infectious Disease in Humanitarian Settings: Lessons Learned from Ebola, Zika, and COVID-19 to Inform Syndemic Policy Making
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Abstract: The impacts of infectious disease outbreaks, epidemics, and pandemics are not gender neutral. Instead, infectious diseases and gender-based violence (GBV) mutually reinforce each …		 MELISSA MEINHART et. al. Conflict and health 2021-11-20
85 Functional Importance of Hydrophobic Patches on The Ebola Virus VP35 IFN-Inhibitory Domain
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Abstract: Viral protein 35 (VP35) of Ebola virus (EBOV) is a multifunctional protein that mainly acts as a viral polymerase cofactor and an interferon antagonist. VP35 interacts with the …		 NODOKA KASAJIMA et. al. Viruses 2021-11-20
86 A Virus-specific Monocyte Inflammatory Phenotype Is Induced By SARS-CoV-2 at The Immune-epithelial Interface
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Abstract: Infection by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) provokes a potentially fatal pneumonia with multiorgan failure, and high systemic inflammation. To gain …		 JULIETTE LEON et. al. Proceedings of the National Academy of Sciences of the … 2021-11-19
87 Prevention of Emerging Infections in Children
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Abstract: Prevention of emerging infections in children is a dynamic arena where substantial medical advances have enabled intervention and prevention of infection outbreaks. This article …		 Thanyawee Puthanakit; Suvaporn Anugulruengkitt; Watsamon Jantarabenjakul; Pediatric clinics of North America 2021-11-19
88 Transient Liver Damage and Hemolysis Are Associated with An Inhibition of Ebola Virus GP Specific Antibody Response and Lymphopenia
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Abstract: Numerous studies have demonstrated the importance of the adaptive immunity for survival against Ebola virus (EBOV) infection. To evaluate the contribution of tissue damage to …		 HUGUES FAUSTHER-BOVENDO et. al. The Journal of infectious diseases 2021-11-17
89 Implications of Glycosaminoglycans on Viral Zoonotic Diseases
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Abstract: Zoonotic diseases are infectious diseases that pass from animals to humans. These include diseases caused by viruses, bacteria, fungi, and parasites and can be transmitted through …		 Sarah Bauer; Fuming Zhang; Robert J Linhardt; Diseases (Basel, Switzerland) 2021-11-17
90 Natural History of Aerosol-Induced Ebola Virus Disease in Rhesus Macaques
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Abstract: Ebola virus disease (EVD) is a serious global health concern because case fatality rates are approximately 50% due to recent widespread outbreaks in Africa. Well-defined nonhuman …		 ISAAC DOWNS et. al. Viruses 2021-11-17
91 Increasing Ebola Transmission Behaviors 6 months Post-vaccination: Comparing Vaccinated and Unvaccinated Populations Near 2018 Mbandaka Ebola Outbreak in The Democratic Republic of Congo
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Abstract: In 2018, the Democratic Republic of the Congo (DRC) declared its 9th and 10th Zaire ebolavirus (EBOV) outbreaks, in the Equateur province (end: July 2018), and in the eastern …		 NICOLE A HOFF et. al. Vaccine 2021-11-16
92 The Network Epidemiology of An Ebola Epidemic
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Highlight: Here, we revisit one of the largest public health efforts deployed against a localized epidemic: the 2014-2016 Ebola Virus Disease (EVD) epidemic in Sierra Leone.		 LAURENT HÉBERT-DUFRESNE et. al. arxiv-q-bio.PE 2021-11-16
93 Registered Nurses’ Perceptions After A Patient with Ebola Virus Disease Is Admitted to Their Hospital
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Abstract: Emerging diseases affect the nursing workforce, but little is known about the willingness of registered nurses (RNs) to work during outbreaks (eg, Ebola virus disease, COVID-19). …		 Nanci Nagel; Helen Salisbury; Holly Hinson; Health security 2021-11-15
94 A Cryptic Pocket in Ebola VP35 Allosterically Controls RNA Binding
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Highlight: Here, we apply a general pipeline for identifying cryptic pockets to the interferon inhibitory domain (IID) of Ebola viral protein 35 (VP35).		 M. A. CRUZ et. al. bio.biochemistry 2021-11-15
95 Adenovirus Vector-based Vaccine for Infectious Diseases
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Abstract: Replication-incompetent adenovirus (Ad) vectors have been widely used as gene delivery vehicles in both gene therapy studies and basic studies for gene function analysis due to …		 Fuminori Sakurai; Masashi Tachibana; Hiroyuki Mizuguchi; Drug metabolism and pharmacokinetics 2021-11-12
96 Fear, Distress, and Perceived Risk Shape Stigma Toward Ebola Survivors: A Prospective Longitudinal Study
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Abstract: During the 2014-15 Ebola Virus Disease (EVD) epidemic, thousands of people in Sierra Leone were infected with the devastating virus and survived. Years after the epidemic was …		 CARA M ANTONACCIO et. al. BMC public health 2021-11-11
97 Evolutionary and Antigenic Profiling of The Tendentious D614G Mutation of SARS-CoV-2 in Gujarat, India
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Abstract: Humankind has suffered many pandemics in history including measles, SARS, MERS, Ebola, and recently the novel Coronavirus disease caused by SARS-CoV-2. As of September 2021, it …		 JAY NIMAVAT et. al. Frontiers in genetics 2021-11-11
98 High-throughput Sequencing of Faeces Provides Evidence for Dispersal of Parasites and Pathogens By Migratory Waterbirds
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Abstract: Examination of faecal material has demonstrated how a broad range of organisms are distributed by bird movements. Such research has largely focused on dispersal of plant seeds by …		 ANDREW G BRISCOE et. al. Molecular ecology resources 2021-11-10
99 Structure and Function of Negative-strand RNA Virus Polymerase Complexes
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Abstract: Viruses with negative-strand RNA genomes (NSVs) include many highly pathogenic and economically devastating disease-causing agents of humans, livestock, and plants-highlighted by …		 Jesse D Pyle; Sean P J Whelan; Louis-Marie Bloyet; The Enzymes 2021-11-10
100 Cellular and Humoral Immunity to Ebola Zaire Glycoprotein and Viral Vector Proteins Following Immunization with Recombinant Vesicular Stomatitis Virus-Based Ebola Vaccine (rVSV{triangleup}G-EBOV-GP)
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Abstract: While effective at preventing Zaire ebolavirus (EBOV) disease, cellular immunity to EBOV and vector-directed immunity elicited by the recombinant vesicular stomatitis virus …		 V. N. RAABE et. al. med.infectious-diseases 2021-11-10
101 Species-specific Quantification of Circulating Ebolavirus Burden Using VP40-derived Peptide Variants
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Abstract: Six ebolavirus species are reported to date, including human pathogens Bundibugyo virus (BDBV), Ebola virus (EBOV), Sudan virus (SUDV), and Taï Forest virus (TAFV); non-human …		 QINGBO SHU et. al. PLoS pathogens 2021-11-08
102 Nanotechnology Applications of Flavonoids for Viral Diseases
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Abstract: Recent years have witnessed the emergence of several viral diseases, including various zoonotic diseases such as the current pandemic caused by the Severe Acute Respiratory …		 KHOSHNUR JANNAT et. al. Pharmaceutics 2021-11-08
103 Malaria and COVID-19: A Double Battle for Burundi
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Abstract: Malaria has become a serious public health concern in Burundi. An outbreak that has the potential to evolve into an epidemic has eradicated nearly as many individuals as the Ebola …		 PARVATHY MOHANAN et. al. African journal of emergency medicine : Revue africaine de … 2021-11-05
104 Deep Time Structural Evolution of Retroviral and Filoviral Surface Envelope Proteins
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Abstract: The retroviral surface envelope protein subunit (SU) mediates receptor binding and triggers membrane fusion by the transmembrane subunit (TM). SU evolves rapidly under strong …		 I. Hotzel; bio.microbiology 2021-11-05
105 Therapeutic Vaccination Strategies Against EBOV By RVSV-EBOV-GP: The Role of Innate Immunity
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Abstract: Zaire Ebola virus (EBOV) is a member of the Filoviridae family. Infection with EBOV causes Ebola virus disease (EVD) characterized by excessive inflammation, lymphocyte death, …		 Amanda N Pinski; Ilhem Messaoudi; Current opinion in virology 2021-11-05
106 A Qualitative Study of COVID-19 Related Reasons for Delayed Presentation of Patients with Chest Pain During The COVID-19 Pandemic
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Abstract: In previous pandemics such as the Ebola virus outbreak in West Africa, it has been observed that patients with non-pandemic related complaints, delay their presentation to …		 Hanlie Dreyer; Katya De Oliveira; Vidya Lalloo; Andreas Engelbrecht; African journal of emergency medicine : Revue africaine de … 2021-11-05
107 Comparison of Viral RNA-host Protein Interactomes Across Pathogenic RNA Viruses Informs Rapid Antiviral Drug Discovery for SARS-CoV-2
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Abstract: In contrast to the extensive research about viral protein-host protein interactions that has revealed major insights about how RNA viruses engage with host cells during infection, …		 SHAOJUN ZHANG et. al. Cell research 2021-11-04
108 Electronic Data Management for Vaccine Trials in Low Resource Settings: Upgrades, Scalability, and Impact of ODK
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Abstract: ODK provides software and standards that are popular solutions for off-grid electronic data collection and has substantial code overlap and interoperability with a number of …		 MICHAEL MARKS et. al. Frontiers in public health 2021-11-04
109 What Effect Might Border Screening Have on Preventing The Importation of COVID-19 Compared with Other Infections? A Modelling Study
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Abstract: The effectiveness of screening travellers during times of international disease outbreak is contentious, especially as the reduction in the risk of disease importation can be very …		 Declan Bays; Emma Bennett; Thomas Finnie; Epidemiology and infection 2021-11-04
110 Sector-by-sector Analysis of Dependence Dynamics Between Global Large-cap Companies and Infectious Diseases: A Time-varying Copula Approach in EBOV and COVID-19 Episodes
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Abstract: Infectious diseases and widespread outbreaks influence different sectors of the economy, including the stock market. In this article, we investigate the effect of EBOV and …		 Mahdi Ghaemi Asl; Hamid Reza Tavakkoli; Muhammad Mahdi Rashidi; PloS one 2021-11-03
111 Establishing Healthcare Worker Performance and Safety in Providing Critical Care for Patients in A Simulated Ebola Treatment Unit: Non-Randomized Pilot Study
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Abstract: Improving the provision of supportive care for patients with Ebola is an important quality improvement initiative. We designed a simulated Ebola Treatment Unit (ETU) to assess …		 PETER KIIZA et. al. Viruses 2021-11-02
112 Glycopeptide Antibiotic Teicoplanin Inhibits Cell Entry of SARS-CoV-2 By Suppressing The Proteolytic Activity of Cathepsin L
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Highlight: Here, we found that the cleavage sites of CTSL on the Spike of SARS-CoV-2 were highly conserved among all the variants.		 F. YU et. al. bio.microbiology 2021-11-01
113 Post-Ebola Sequelae Among Ebola Child Survivors in Sierra Leone
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Abstract: There are limited data regarding the long-term health effects of child survivors of the 2013-2016 West African Ebola virus disease (EVD) outbreak. Here, we assess post-Ebola …		 Claudette Amuzu; Peter Bai James; Abdulai Jawo Bah; Alex Vandy Saffa Bayoh; Shepherd Roee Singer; BMC pediatrics 2021-10-30
114 Human Parainfluenza Virus 3 Phosphoprotein Is A Tetramer and Shares Structural and Interaction Features with Ebola Phosphoprotein VP35
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Abstract: The human parainfluenza virus 3 (HPIV3) poses a risk for pneumonia development in young children and immunocompromised patients. To investigate mechanisms of HPIV3 pathogenesis, …		 JOAQUIN RODRIGUEZ GALVAN et. al. Biomolecules 2021-10-29
115 Safety and Immunogenicity of 2-dose Heterologous Ad26.ZEBOV, MVA-BN-Filo Ebola Vaccination in Healthy and HIV-infected Adults: A Randomised, Placebo-controlled Phase II Clinical Trial in Africa
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Abstract: We investigated safety, tolerability, and immunogenicity of the heterologous 2-dose Ebola vaccination regimen in healthy and HIV-infected adults with different intervals between …		 HOURERATOU BARRY et. al. PLoS medicine 2021-10-29
116 Tolerance and Persistence of Ebola Virus in Primary Cells from Mops Condylurus , A Potential Ebola Virus Reservoir
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Abstract: Although there have been documented Ebola virus disease outbreaks for more than 40 years, the natural reservoir host has not been identified. Recent studies provide evidence that …		 MARCEL BOKELMANN et. al. Viruses 2021-10-29
117 Modulating Neurological Complications of Emerging Infectious Diseases: Mechanistic Approaches to Candidate Phytochemicals
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Abstract: Growing studies are revealing the critical manifestations of influenza, dengue virus (DENV) infection, Zika virus (ZIKV) disease, and Ebola virus disease (EVD) as emerging …		 Sajad Fakhri; Pardis Mohammadi Pour; Sana Piri; Mohammad Hosein Farzaei; Javier Echeverría; Frontiers in pharmacology 2021-10-26
118 Identification and Characterization of Short Leader and Trailer RNAs Synthesized By The Ebola Virus RNA Polymerase
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Abstract: Transcription of non-segmented negative sense (NNS) RNA viruses follows a stop-start mechanism and is thought to be initiated at the genome’s very 3′-end. The synthesis of short …		 SIMONE BACH et. al. PLoS pathogens 2021-10-26
119 Gut Microbiota of Bats: Pro-mutagenic Properties and Possible Frontiers in Preventing Emerging Disease
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Abstract: Bats are potential natural reservoirs for emerging viruses, causing deadly human diseases, such as COVID-19, MERS, SARS, Nipah, Hendra, and Ebola infections. The fundamental …		 IGOR V POPOV et. al. Scientific reports 2021-10-26
120 Scalable Bayesian Divergence Time Estimation with Ratio Transformations
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Highlight: To overcome this limitation, we explore a ratio transformation that maps the original N – 1 internal node heights into a space of one height parameter and N – 2 ratio parameters.		 XIANG JI et. al. arxiv-q-bio.PE 2021-10-25
121 Coexpression of Respiratory Syncytial Virus (RSV) Fusion (F) Protein and Attachment Glycoprotein (G) in A Vesicular Stomatitis Virus (VSV) Vector System Provides Synergistic Effects Against RSV Infection in A Cotton Rat Model
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Abstract: Respiratory syncytial virus (RSV) is one of the most important causes of respiratory disease in infants, immunocompromised individuals, and the elderly. Natural infection does not …		 KELSEY A BRAKEL et. al. Vaccine 2021-10-23
122 Characterization of The Therapeutic Effect of Antibodies Targeting The Ebola Glycoprotein Using A Novel BSL2-compliant RVSVΔG-EBOV-GP Infection Model
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Abstract: Ebola virus (EBOV) infections cause haemorrhagic fever, multi-organ failure and death, and survivors can experience neurological sequelae. Licensing of monoclonal antibodies …		 HA-NA LEE et. al. Emerging microbes & infections 2021-10-22
123 Ebola Viral Receptor Niemann-Pick C1 (NPC1) in Human Cancers: A Potential Biomarker and Immunotherapeutic Target
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 Zhen Fang; Peijuan Li; Liang Shang; Fei Li; Human cell 2021-10-22
124 The Deployment of Mobile Diagnostic Laboratories for Ebola Virus Disease Diagnostics in Sierra Leone and Guinea
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Abstract: Ebola virus emerged in West Africa in December 2013. The ease of mobility, porous borders, and lack of public health infrastructure led to the largest Ebola virus disease (EVD) …		 LANCE D PRESSER et. al. African journal of laboratory medicine 2021-10-22
125 The Private Versus Public Contribution to The Biomedical Literature During The COVID-19, Ebola, H1N1, and Zika Public Health Emergencies
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Abstract: The private versus public contribution to developing new health knowledge and interventions is deeply contentious. Proponents of commercial innovation highlight its role in …		 Reed F Beall; Javad Moradpour; Aidan Hollis; PloS one 2021-10-22
126 Cross-sectional Survey of Knowledge and Attitudes of Healthcare Workers and Community Members Toward The Ebola Virus Disease and Antimicrobial Resistance Pathogens Outbreaks in Nigeria
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Abstract: the 2014 Ebola virus disease (EVD) outbreak in Nigeria has further raised the awareness of health-care workers (HCWs) and community members (MCs) on the threat posed by infectious …		 IBRAHIM YUSUF et. al. The Pan African medical journal 2021-10-22
127 Community Health Workers’ Job Satisfaction in Ebola-stricken Areas of Sierra Leone and Its Implication for COVID-19 Containment: A Cross-sectional Mixed-methods Study
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Abstract: Community health workers (CHWs) played important roles in supplementing scarce healthcare workforce in Sierra Leone during the Ebola outbreak, causing the government to launch the …		 OSMAN KOROMA et. al. BMJ open 2021-10-20
128 How Antibodies Recognize Pathogenic Viruses: Structural Correlates of Antibody Neutralization of HIV-1, SARS-CoV-2, and Zika
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Abstract: The H1N1 pandemic of 2009-2010, MERS epidemic of 2012, Ebola epidemics of 2013-2016 and 2018-2020, Zika epidemic of 2015-2016, and COVID-19 pandemic of 2019-2021, are recent …		 Morgan E Abernathy; Kim-Marie A Dam; Shannon R Esswein; Claudia A Jette; Pamela J Bjorkman; Viruses 2021-10-19
129 Operational Considerations in Global Health Modeling
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Abstract: Epidemiological modeling and simulation can contribute cooperatively across multifaceted areas of biosurveillance systems. These efforts can be used to support real-time …		 KATHERINE M BROADWAY et. al. Pathogens (Basel, Switzerland) 2021-10-19
130 Analysis of The Management of The Tenth Ebola Virus Disease Outbreak in The Democratic Republic of Congo: Developing A Multidisciplinary Response Model to Strengthen The Healthcare System During Disease Outbreaks
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Abstract: The declaration of any public health emergency in the Democratic Republic of Congo (DRC) is usually followed by the provision of technical and organizational support from …		 BIVES MUTUME VIVALYA et. al. Globalization and health 2021-10-18
131 Mechanisms of Immune Evasion By Ebola Virus
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Abstract: The 2013-2016 Ebola virus epidemic in West Africa, which also spread to the USA, UK and Europe, was the largest reported outbreak till date (World Health Organization. 2016. …		 Suchita Bhattacharyya; Advances in experimental medicine and biology 2021-10-18
132 Structural and Functional Aspects of Ebola Virus Proteins
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Abstract: Ebola virus (EBOV), member of genus , family , have a non-segmented, single-stranded RNA that contains seven genes: (a) nucleoprotein (NP), (b) viral protein 35 (VP35), (c) VP40, …		 Sahil Jain; Ekaterina Martynova; Albert Rizvanov; Svetlana Khaiboullina; Manoj Baranwal; Pathogens (Basel, Switzerland) 2021-10-15
133 Bioterrorism
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Abstract: Bioterrorism is the deliberate release of viruses, bacteria, toxins, or fungi with the goal of causing panic, mass casualties, or severe economic disruption. From 1981 to 2018, …		 Nicholas A Rathjen; S David Shahbodaghi; American family physician 2021-10-15
134 Sweet Drugs for Bad Bugs: A Glycomimetic Strategy Against The DC-SIGN-Mediated Dissemination of SARS-CoV-2
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Abstract: The C-type lectin receptor DC-SIGN is a pattern recognition receptor expressed on macrophages and dendritic cells. It has been identified as a promiscuous entry receptor for many …		 JONATHAN CRAMER et. al. Journal of the American Chemical Society 2021-10-15
135 Self-Replicating RNA Viruses for Vaccine Development Against Infectious Diseases and Cancer
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Abstract: Alphaviruses, flaviviruses, measles viruses and rhabdoviruses are enveloped single-stranded RNA viruses, which have been engineered for recombinant protein expression and vaccine …		 Kenneth Lundstrom; Vaccines 2021-10-15
136 ONTdeCIPHER: An Amplicon-based Nanopore Sequencing Pipeline for Tracking Pathogen Variants
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Highlight: Results: Here, we present ONTdeCIPHER, an amplicon-based Oxford Nanopore Technology (ONT) sequencing pipeline to analyze the genetic diversity of SARS-CoV-2 and other pathogenes.		 E. CHERIF et. al. bio.bioinformatics 2021-10-14
137 Accessing Unproven Interventions in The COVID-19 Pandemic: Discussion on The Ethics of ‘compassionate Therapies’ in Times of Catastrophic Pandemics
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Abstract: Since the onset of the SARS-CoV-2 pandemic, an array of off-label interventions has been used to treat patients, either provided as compassionate care or tested in clinical …		 Shlomit Zuckerman; Yaron Barlavie; Yaron Niv; Dana Arad; Shaul Lev; Journal of medical ethics 2021-10-13
138 Infectious Disease in An Era of Global Change
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Abstract: The twenty-first century has witnessed a wave of severe infectious disease outbreaks, not least the COVID-19 pandemic, which has had a devastating impact on lives and livelihoods …		 RACHEL E BAKER et. al. Nature reviews. Microbiology 2021-10-13
139 Increased Human-animal Interface & Emerging Zoonotic Diseases: An Enigma Requiring Multi-sectoral Efforts to Address
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Abstract: Increased human-animal interfaces impose threats on human life by creating scope for the emergence and resurgence of many infectious diseases. Over the last two decades, emergence …		 Falguni Debnath; Debjit Chakraborty; Alok Kumar Deb; Malay Kumar Saha; Shanta Dutta; The Indian journal of medical research 2021-10-13
140 Preparing for Disease X
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Abstract: The past 30 years have exposed the global public health and economic threats posed by the emergence of infectious pathogens with epidemic and pandemic potential. Severe acute …		 Maria D Van Kerkhove; Michael J Ryan; Tedros Adhanom Ghebreyesus; Science (New York, N.Y.) 2021-10-13
141 Identification and Characterization of A Novel Single Domain Antibody Against Ebola Virus
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Abstract: Ebola virus (EBOV) belongs to the Filoviridae family and causes severe illnesses such as hemorrhagic fever with a high mortality rate up to 90%. Now two antibody drugs termed …		 RUI WANG et. al. Virologica Sinica 2021-10-11
142 The Genetic Impact of An Ebola Outbreak on A Wild Gorilla Population
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Abstract: Numerous Ebola virus outbreaks have occurred in Equatorial Africa over the past decades. Besides human fatalities, gorillas and chimpanzees have also succumbed to the fatal virus. …		 CLAUDIA FONTSERE et. al. BMC genomics 2021-10-11
143 Role of Key Infectivity Parameters in The Transmission of Ebola Virus Makona in Macaques
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Abstract: Many characteristics associated with Ebola virus disease remain to be fully understood. It is known that direct contact with infected bodily fluids is an associated risk factor, …		 MARC-ANTOINE DE LA VEGA et. al. The Journal of infectious diseases 2021-10-09
144 Structure, Process, and Outcomes of Liberian National Nursing and Midwifery Curricular Revisions
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Abstract: The Republic of Liberia has had major disruptions to the education of its health care cadres. Post Ebola, the Resilient and Responsive Health Systems (RRHS) initiative began a new …		 CECELIA C KPANGAALA-FLOMO et. al. Annals of global health 2021-10-08
145 HRSA’s PEPFAR-Supported Resilient and Responsive Health Systems Initiative in Liberia
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Abstract: During the 2014-16 Ebola outbreak, Liberia suffered 2,544 deaths, including 8% of its doctors, nurses and midwives. The Government responded in 2016 with a seven-year Health …		 George Tidwell; Myat Htoo Razak; Annals of global health 2021-10-08
146 Liberia’s First Health Workforce Program Strategy: Reflections and Lessons Learned
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Abstract: Following civil war and the Ebola epidemic, Liberia’s health workforce was devastated, essential health services and primary care were disrupted, and health outcomes for maternal …		 BERNICE DAHN et. al. Annals of global health 2021-10-08
147 Facing COVID-19 in Liberia: Adaptations of The Resilient and Responsive Health Systems Initiative
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Abstract: The 5-year Resilient and Responsive Health Systems (RRHS)-Liberia Initiative, funded by PEPFAR via HRSA, launched in 2017 and was designed to support the implementation of …		 REGAN H MARSH et. al. Annals of global health 2021-10-08
148 Health Management Workforce Capacity-Building in Liberia, Post-Ebola
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Abstract: Following the Ebola crisis in Liberia in 2014-15, the Liberian Ministry of Health developed a strategy to build a fit-for-purpose health workforce, focusing on both health care …		 KRISTINA TALBERT-SLAGLE et. al. Annals of global health 2021-10-08
149 A Bioinspired Neural Architecture Search Based Convolutional Neural Network for Breast Cancer Detection Using Histopathology Images
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Abstract: The design of neural architecture to address the challenge of detecting abnormalities in histopathology images can leverage the gains made in the field of neural architecture …		 Olaide N Oyelade; Absalom E Ezugwu; Scientific reports 2021-10-07
150 Development and Characterization of Influenza M2 Ectodomain And/or HA Stalk-based DC-targeting Vaccines for Different Influenza Infections
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Highlight: Here, we revealed the efficacy of novel influenza vaccine candidates based on Ebola glycoprotein (EboGP) DC-targeting domain (E{Delta}M) fusion protein technology.		 X. YAO et. al. bio.microbiology 2021-10-07
151 The Epidemic Failure Cycle Hypothesis: Towards Understanding The Global Community’s Recent Failures in Responding to An Epidemic
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Abstract: Within a few years, the global community has failed twice in responding to large viral infection outbreaks: the Ebola epidemic in 2014 and the SARS-Cov-2 pandemic in 2020. There …		 Dirk Richter; Simeon Zuercher; Journal of infection and public health 2021-10-06
152 Expanded Histopathology and Tropism of Ebola Virus in The Rhesus Macaque Model: Potential for Sexual Transmission, Altered Adrenomedullary Hormone Production, and Early Viral Replication in Liver
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Abstract: The pathogenesis of Ebola virus disease (EVD) is still incomplete, in spite of the availability of a nonhuman primate modelfor more than 4 decades. To further investigate EVD …		 DAVID X LIU et. al. The American journal of pathology 2021-10-06
153 Equitable Data Sharing in Epidemics and Pandemics
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Abstract: Rapid data sharing can maximize the utility of data. In epidemics and pandemics like Zika, Ebola, and COVID-19, the case for such practices seems especially urgent and warranted. …		 Bridget Pratt; Susan Bull; BMC medical ethics 2021-10-06
154 On-Demand Patient-Specific Phenotype-to-Genotype Ebola Virus Characterization
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Abstract: Biosafety, biosecurity, logistical, political, and technical considerations can delay or prevent the wide dissemination of source material containing viable virus from the …		 BRETT F BEITZEL et. al. Viruses 2021-10-06
155 COVID-19 Vaccines: Adenoviral Vectors
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Abstract: The worldwide pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to the unprecedented pace of …		 Catherine Jacob-Dolan; Dan H Barouch; Annual review of medicine 2021-10-05
156 Establishment of Intestinal Organoid from Rousettus Leschenaultii and The Susceptibility to Bat-Associated Viruses, SARS-CoV-2 and Pteropine Orthoreovirus
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Abstract: Various pathogens, such as Ebola virus, Marburg virus, Nipah virus, Hendra virus, Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV), Middle East Respiratory Syndrome …		 MOHAMED ELBADAWY et. al. International journal of molecular sciences 2021-10-05
157 The Role of Animal Research in Pandemic Responses
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Abstract: The significant advances made by the global scientific community during the COVID-19 pandemic, exemplified by the development of multiple SARS-CoV-2 vaccines in less than 1 y, …		 Jacqueline K Brockhurst; Jason S Villano; Comparative medicine 2021-10-05
158 A Magneto-optical Biochip for Rapid Assay Based on The Cotton-Mouton Effect of Γ-Fe 2 O 3 @Au Core/shell Nanoparticles
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Abstract: In the past decades, different diseases and viruses, such as Ebola, MERS and COVID-19, impacted the human society and caused huge cost in different fields. With the increasing …		 Kuen-Lin Chen; Zih-Yan Yang; Chin-Wei Lin; Journal of nanobiotechnology 2021-10-01
159 Immunocompromised Cas9 Transgenic Mice for Rapid In vivo Assessment of Host Factors Involved in Highly Pathogenic Virus Infection
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Abstract: Targeting host factors for anti-viral development offers several potential advantages over traditional countermeasures that include broad-spectrum activity and prevention of …		 NICOLE COLLETTE et. al. Molecular therapy. Methods & clinical development 2021-10-01
160 Pandemic-related Racial Discrimination and Its Health Impact Among Non-Indigenous Racially Minoritized Peoples in High-income Contexts: A Systematic Review
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Abstract: This study aims to review articles reporting the perspectives and experiences of pandemic-related discrimination among racially minoritized peoples in high-income contexts. We …		 Aryati Yashadhana; Alexia Derbas; Jessica Biles; Julian Grant; Health promotion international 2021-10-01
161 The Computational Quantum Mechanical Investigation of The Functionalized Boron Nitride Nanocage As The Smart Carriers for Favipiravir Drug Delivery: A DFT and QTAIM Analysis
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Abstract: Favipiravir (FPV) is an antiviral drug used for the cure of Influenza virus, Ebola virus, Lassa virus etc. because it has excellent preventing ability of entry/exit of the virus …		 MD MEHADE HASAN et. al. Journal of biomolecular structure & dynamics 2021-10-01
162 Coronavirus Disease 2019 on The Heels of Ebola Virus Disease in West Africa
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Abstract: This study utilized modeling and simulation to examine the effectiveness of current and potential future COVID-19 response interventions in the West African countries of Guinea, …		 ZYGMUNT F DEMBEK et. al. Pathogens (Basel, Switzerland) 2021-10-01
163 Remdesivir Is Efficacious in Rhesus Monkeys Exposed to Aerosolized Ebola Virus
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Abstract: Efficacious therapeutics for Ebola virus disease are in great demand. Ebola virus infections mediated by mucosal exposure, and aerosolization in particular, present a novel …		 TRAVIS K WARREN et. al. Scientific reports 2021-09-30
164 Estimation of Ebola’s Spillover Infection Exposure in Sierra Leone Based on Sociodemographic and Economic Factors
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Highlight: To that end, we designed and conducted a survey in Sierra Leone and implement a pipeline to analyze data using regression and machine learning techniques.		 SENA MURSEL et. al. arxiv-q-bio.PE 2021-09-30
165 Heterologous Prime-boost Regimens with HAdV-5 and NDV Vectors Elicit Stronger Immune Responses to Ebola Virus Than Homologous Regimens in Mice
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Abstract: The 2014 Ebola outbreak in West Africa resulted in more than 11,000 deaths, highlighting the need for a vaccine. A phase I clinical trial of a human adenovirus type 5 vector-based …		 WEI ZHAO et. al. Archives of virology 2021-09-30
166 Pyronaridine Protects Against SARS-CoV-2 in Mouse
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Highlight: We used this as justification to evaluate three molecules we had previously identified computationally with antiviral activity against Ebola and Marburg.		 A. C. PUHL et. al. bio.pharmacology-and-toxicology 2021-09-30
167 Reovirus Infection Is Regulated By NPC1 and Endosomal Cholesterol Homeostasis
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Highlight: We identified NPC1 in CRISPR and RNA interference screens as a putative host factor for infection by mammalian orthoreovirus (reovirus).		 P. ORTEGA GONZALEZ et. al. bio.cell-biology 2021-09-30
168 Qualitative Review of Organizational Responses to Rumors in The 2014-2016 Ebola Virus Disease Outbreak in Liberia and Sierra Leone
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Abstract: Rumors and misperceptions were a persistent challenge in the response to the 2014-2016 Ebola Virus Disease (EVD) outbreak in West Africa. This study aimed to document …		 Amelia J Brandt; Bonnie Katalenich; David W Seal; Global health, science and practice 2021-09-30
169 Synthetic Nanobody-Functionalized Nanoparticles for Accelerated Development of Rapid, Accessible Detection of Viral Antigens
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Highlight: Here we present a generalizable assay platform, nanobody-functionalized nanoparticles for rapid, electronic detection (Nano2RED), demonstrated in the detection of Ebola and COVID-19 antigens.		 X. CHEN et. al. bio.bioengineering 2021-09-30
170 A Virus-specific Monocyte Inflammatory Phenotype Is Induced By SARS-CoV2 at The Immune-epithelial Interface
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Highlight: To gain mechanistic insight and ferret out the root of this immune dysregulation, we modeled by in vitro co-culture the interactions between infected epithelial cells and immunocytes.		 J. LEON et. al. bio.immunology 2021-09-29
171 Zoonotic Potential of A Novel Bat Morbillivirus
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Abstract: Bats are significant reservoir hosts for many viruses with zoonotic potential1. SARS-CoV-2, Ebola virus, and Nipah virus are examples of such viruses that have caused deadly …		 BENHUR LEE et. al. Research square 2021-09-29
172 The Manifold Roles of Sphingolipids in Viral Infections
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Abstract: Sphingolipids are essential components of eukaryotic cells. In this review, we want to exemplarily illustrate what is known about the interactions of sphingolipids with various …		 ELITA AVOTA et. al. Frontiers in physiology 2021-09-29
173 Versatile and Rapid Microfluidics-assisted Antibody Discovery
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Abstract: Recent years have seen unparalleled development of microfluidic applications for antibody discovery in both academic and pharmaceutical research. Microfluidics can support native …		 RAMONA GAA et. al. mAbs 2021-09-29
174 DR Congo: WHO Staff Abused Women and Girls in Ebola Outbreak, Says harrowing Independent Report
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 Jacqui Wise; BMJ (Clinical research ed.) 2021-09-29
175 Dose-Dependent Response to Infection with Ebola Virus in The Ferret Model and Evidence of Viral Evolution in The Eye
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Abstract: Filoviruses cause high-consequence infections with limited approved medical countermeasures (MCMs). MCM development is dependent upon well-characterized animal models for the …		 ROBERT J WATSON et. al. Journal of virology 2021-09-29
176 Ethanol Inactivation of Enveloped Viruses: Structural and Surface Chemistry Insights Into Phi6
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Abstract: Lipid-enveloped viruses, such as Ebola, influenza, or coronaviruses, are a major threat to human health. Ethanol is an efficient disinfectant that is widely used to inactivate …		 Samuel Watts; Madeleine Ramstedt; Stefan Salentinig; The journal of physical chemistry letters 2021-09-28
177 Open-label, Randomised, Clinical Trial to Evaluate The Immunogenicity and Safety of A Prophylactic Vaccination of Healthcare Providers By Administration of A Heterologous Vaccine Regimen Against Ebola in The Democratic Republic of The Congo: The Study Protocol
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Abstract: This article describes the protocol of an Ebola vaccine clinical trial which investigates the safety and immunogenicity of a two-dose prophylactic Ebola vaccine regimen comprised …		 YNKE LARIVIÈRE et. al. BMJ open 2021-09-28
178 A Systematic Review and Meta-analysis on The Prevalence of Stigma in Infectious Diseases, Including COVID-19: A Call to Action
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Abstract: Infectious diseases, including COVID-19, are crucial public health issues and may lead to considerable fear among the general public and stigmatization of, and discrimination …		 KAI YUAN et. al. Molecular psychiatry 2021-09-27
179 Triangulating Evidence to Infer Pathways That Influence Ebola Virus Disease-Related Stigma and Clinical Findings Among Survivors: An Observational Cohort Study
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Abstract: Visible signs of disease can evoke stigma while stigma contributes to depression and mental illness, sometimes manifesting as somatic symptoms. We assessed these hypotheses among …		 J DANIEL KELLY et. al. The American journal of tropical medicine and hygiene 2021-09-27
180 Assessing The Management of Healthcare Waste for Disease Prevention and Environment Protection at Selected Hospitals in Kinshasa, Democratic Republic of Congo
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Abstract: Incineration is the most used healthcare waste (HCW) disposal method. Disease outbreaks due to Ebola virus and SARS-CoV2 require attention to HCW management to avoid pathogens …		 Gabriel Kalombe Kyomba; Joêl Nkiama Numbi Konde; Diafuka Saila-Ngita; Thomas Kuanda Solo; Guillaume Mbela Kiyombo; Waste management & research : the journal of the … 2021-09-27
181 Post-exposure Prophylaxis Following High-risk Contact with Ebola Virus, Using Immunotherapies with Monoclonal Antibodies, in The Eastern Democratic Republic of The Congo: An Emergency Use Program
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Abstract: With the development of therapeutics and vaccine against Ebola virus disease (EVD), the question of post-exposure prophylaxis for high-risk contact has emerged. Immunotherapies …		 MARIE JASPARD et. al. International journal of infectious diseases : IJID : … 2021-09-26
182 Ginkgolic Acid Inhibits Coronavirus Strain 229E Infection of Human Epithelial Lung Cells
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Abstract: Since December 2019, the COVID-19 pandemic has affected more than 200 million individuals around the globe and caused millions of deaths. Although there are now multiple vaccines …		 MAIMOONA S BHUTTA et. al. Pharmaceuticals (Basel, Switzerland) 2021-09-26
183 COVID-19 Vaccine and The Cold Chain Implications for Global Adoption
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Abstract: The COVID-19 pandemic has spread globally with 190.8 million infected cases and 4.1 million deaths as of July 18, 2021. In absence of any definite antiviral agent availability and …		 Manoja Kumar Das; Indian journal of public health 2021-09-24
184 A Computational Overview on Phylogenetic Characterization, Pathogenic Mutations, and Drug Targets for Ebola Virus Disease
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Abstract: The World Health Organization declared Ebola virus disease (EVD) as the major outbreak in the 20th century. EVD was first identified in 1976 in South Sudan and the Democratic …		 KARTHICK VASUDEVAN et. al. Current opinion in pharmacology 2021-09-24
185 Identification of A Dual Acting SARS-CoV-2 Proteases Inhibitor Through in Silico Design and Step-by-step Biological Characterization
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Abstract: COVID-19 pandemic, starting from the latest 2019, and caused by SARS-CoV-2 pathogen, led to the hardest health-socio-economic disaster in the last century. Despite the tremendous …		 VERONICA DI SARNO et. al. European journal of medicinal chemistry 2021-09-22
186 A Review of THz Technologies for Rapid Sensing and Detection of Viruses Including SARS-CoV-2
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Abstract: Virus epidemics such as Ebola virus, Zika virus, MERS-coronavirus, and others have wreaked havoc on humanity in the last decade. In addition, a coronavirus (SARS-CoV-2) pandemic …		 Naznin Akter; Muhammad Mahmudul Hasan; Nezih Pala; Biosensors 2021-09-22
187 Synthesis and Antiviral Activity of Fatty Acyl Conjugates of Remdesivir Against Severe Acute Respiratory Syndrome Coronavirus 2 and Ebola Virus
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Abstract: We report here the synthesis, purification, and characterization of mono- and di-fatty acyl conjugates of remdesivir (RDV) and their in vitro antiviral activity against SAR-CoV-2, …		 NAGLAA SALEM EL-SAYED et. al. European journal of medicinal chemistry 2021-09-21
188 The Suppressor of Cytokine Signalling Family of Proteins and Their Potential Impact on COVID-19 Disease Progression
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Abstract: The family of Suppressor of Cytokine Signalling (SOCS) proteins plays pivotal roles in cytokine and immune regulation. Despite their key roles, little attention has been given to …		 Zheng Yao Low; Ashley Jia Wen Yip; Vincent T K Chow; Sunil K Lal; Reviews in medical virology 2021-09-21
189 An Update on The Progress of Galidesivir (BCX4430), A Broad-spectrum Antiviral
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Abstract: Galidesivir (BCX4430) is an adenosine nucleoside analog that is broadly active in cell culture against several RNA viruses of various families. This activity has also been shown …		 JUSTIN G JULANDER et. al. Antiviral research 2021-09-20
190 Pandemics Throughout The History
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Abstract: As we move amidst the coronavirus disease 2019 (COVID-19) pandemic, we have witnessed tremendous distress, death, and turmoil of everyday life for more than one year now. However, …		 SHRIKANTH SAMPATH et. al. Cureus 2021-09-20
191 Selection of Filovirus Isolates for Vaccine Development Programs
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Abstract: The continuing outbreaks of ebola virus disease highlight the ongoing threat posed by filoviruses. Fortunately, licensed vaccines and therapeutics are now available for . However, …		 DANIEL N WOLFE et. al. Vaccines 2021-09-19
192 COVID-19 and Beyond: How Lessons and Evidence from Implementation Research Can Benefit Health Systems’ Response and Preparedness for COVID-19 and Future Epidemics
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Abstract: Early in the COVID-19 pandemic-and based on limited data on the novel coronavirus-it was projected that African countries will be ravaged and the health systems overwhelmed. …		 Nafissatou Diop; Montasser Kamal; Marie Renaud; Sana Naffa; Family medicine and community health 2021-09-18
193 Genetic Diversity of Bat Coronaviruses and Comparative Genetic Analysis of MERS-related Coronaviruses in South Korea
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Abstract: Bats have been identified as a natural reservoir of several potentially zoonotic viruses, including Lyssavirus, Ebola virus, Marburg virus, Hendra virus, Nipah virus, as well as …		 SOOK-YOUNG LEE et. al. Transboundary and emerging diseases 2021-09-18
194 Zoonotic Potential of A Novel Bat Morbillivirus
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Highlight: Here, we identify and characterize a novel morbillivirus from a vespertilionid bat species (Myotis riparius) in Brazil, which we term myotis bat morbillivirus (MBaMV).		 S. IKEGAME et. al. bio.microbiology 2021-09-17
195 The Ebola Virus Soluble Glycoprotein Contributes to Viral Pathogenesis By Activating The MAP Kinase Signaling Pathway
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Abstract: Ebola virus (EBOV) expresses three different glycoproteins (GPs) from its GP gene. The primary product, soluble GP (sGP), is secreted in abundance during infection. EBOV sGP has …		 Wakako Furuyama; Kyle Shifflett; Heinz Feldmann; Andrea Marzi; PLoS pathogens 2021-09-16
196 The 2013-2016 Ebola Virus Disease Outbreak in West Africa
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Abstract: The largest, longest, and deadliest ever-recorded outbreak of Ebola virus disease in human history occurred in West Africa from December 2013 to March 2016 causing 28,652 …		 Elijah Ige Ohimain; Daniel Silas-Olu; Current opinion in pharmacology 2021-09-16
197 An Ebola, Neisseria and Trypanosoma Human Protein Interaction Census Reveals A Conserved Human Protein Cluster Targeted By Various Human Pathogens
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Abstract: (ZE; , Bundibugyo ebolavirus), (NM), and (Tb) are serious infectious pathogens, spanning viruses, bacteria and protists and all may target the blood and central nervous system …		 Shishir K Gupta; Alicia Ponte-Sucre; Elena Bencurova; Thomas Dandekar; Computational and structural biotechnology journal 2021-09-16
198 Filovirus Neutralising Antibodies: Mechanisms of Action and Therapeutic Application
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Abstract: Filoviruses, especially Ebola virus, cause sporadic outbreaks of viral haemorrhagic fever with very high case fatality rates in Africa. The 2013-2016 Ebola epidemic in West Africa …		 ALEXANDER HARGREAVES et. al. Pathogens (Basel, Switzerland) 2021-09-16
199 Ebola Virus Can Lie Low and Reactivate After Years in Human Survivors
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 Robert F Garry; Nature 2021-09-16
200 PANoptosis in Viral Infection: The Missing Puzzle Piece in The Cell Death Field
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Abstract: In the past decade, emerging viral outbreaks like SARS-CoV-2, Zika and Ebola have presented major challenges to the global health system. Viruses are unique pathogens in that they …		 Lam Nhat Nguyen; Thirumala-Devi Kanneganti; Journal of molecular biology 2021-09-16
201 Comparison of Machine Learning Methods for Estimating Case Fatality Ratios: An Ebola Outbreak Simulation Study
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Abstract: Machine learning (ML) algorithms are now increasingly used in infectious disease epidemiology. Epidemiologists should understand how ML algorithms behave within the context of …		 Alpha Forna; Ilaria Dorigatti; Pierre Nouvellet; Christl A Donnelly; PloS one 2021-09-15
202 Resurgence of Ebola Virus in 2021 in Guinea Suggests A New Paradigm for Outbreaks
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Abstract: Seven years after the declaration of the first epidemic of Ebola virus disease in Guinea, the country faced a new outbreak-between 14 February and 19 June 2021-near the epicentre …		 ALPHA KABINET KEITA et. al. Nature 2021-09-15
203 Low-Valent Calix[4]arene Glycoconjugates Based on Hydroxamic Acid Bearing Linkers As Potent Inhibitors in A Model of Ebola Virus Cis-Infection and HCMV-gB-Recombinant Glycoprotein Interaction with MDDC Cells By Blocking DC-SIGN
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Abstract: In addition to a variety of viral-glycoprotein receptors (e.g., heparan sulfate, Niemann-Pick C1, etc.), dendritic cell-specific intercellular adhesion molecule-3-grabbing …		 KHOULOUD CHAKROUN et. al. Journal of medicinal chemistry 2021-09-15
204 Immunophenotyping and Transcriptional Profiling of Human Plasmablasts in Dengue
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Abstract: Plasmablasts represent a specialized class of antibody-secreting effector B cells that transiently appear in blood circulation following infection or vaccination. The expansion of …		 CHARU AGGARWAL et. al. Journal of virology 2021-09-15
205 Safety and Immunogenicity of The Two-dose Heterologous Ad26.ZEBOV and MVA-BN-Filo Ebola Vaccine Regimen in Children in Sierra Leone: A Randomised, Double-blind, Controlled Trial
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Abstract: Children account for a substantial proportion of cases and deaths from Ebola virus disease. We aimed to assess the safety and immunogenicity of a two-dose heterologous vaccine …		 MUHAMMED O AFOLABI et. al. The Lancet. Infectious diseases 2021-09-13
206 Safety and Long-term Immunogenicity of The Two-dose Heterologous Ad26.ZEBOV and MVA-BN-Filo Ebola Vaccine Regimen in Adults in Sierra Leone: A Combined Open-label, Non-randomised Stage 1, and A Randomised, Double-blind, Controlled Stage 2 Trial
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Abstract: The Ebola epidemics in west Africa and the Democratic Republic of the Congo highlight an urgent need for safe and effective vaccines to prevent Ebola virus disease. We aimed to …		 DAVID ISHOLA et. al. The Lancet. Infectious diseases 2021-09-13
207 Knowledge, Attitude and Practice of Sudanese Health Care Providers Toward Ebola Virus Outbreak
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Abstract: Ebola virus disease (EVD) is a highly contagious and fatal disease in humans. Healthcare providers (HCPs) are often at the frontline of epidemics and can thus be in jeopardy of …		 Ezzan Kunna; Taro Yamamoto; Sabin Nundu; Calliope Akintije; Isam Elkhidir; Acta medica Okayama 2021-09-13
208 Interferon-Induced HERC5 Inhibits Ebola Virus Particle Production and Is Antagonized By Ebola Glycoprotein
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Abstract: Survival following Ebola virus (EBOV) infection correlates with the ability to mount an early and robust interferon (IFN) response. The host IFN-induced proteins that contribute …		 ERMELA PAPARISTO et. al. Cells 2021-09-13
209 The Impact of Providing End-of-life Care During A Pandemic on The Mental Health and Wellbeing of Health and Social Care Staff: Systematic Review and Meta-synthesis
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Abstract: Disease outbreaks and disasters can result in excess deaths and severe disruption of usual end-of-life care processes. We aimed to: i) synthesise evidence describing the …		 Bryony Porter; Amy Zile; Guy Peryer; Morag Farquhar; Kristy Sanderson; Social science & medicine (1982) 2021-09-13
210 Ebola Vaccines for Mass Immunisation in Affected Regions
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 Selidji Todagbe Agnandji; Marguerite Massinga Loembe; The Lancet. Infectious diseases 2021-09-13
211 Third-generation Smallpox Vaccine Strain-based Recombinant Vaccines for Viral Hemorrhagic Fevers
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Abstract: Vaccinia virus has been used as a smallpox vaccine. Now that smallpox has been eradicated, the vaccinia virus is expected to be used as a bioterrorism countermeasure and a …		 Tomoki Yoshikawa; Vaccine 2021-09-11
212 The Impact of The 2014 Ebola Epidemic on HIV Disease Burden and Outcomes in Liberia West Africa
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Abstract: Detailed longitudinal studies of HIV-positive individuals in West Africa are lacking. Here the HIV prevalence, incidence, all-cause mortality, and the proportion of individuals …		 SOKA J MOSES et. al. PloS one 2021-09-10
213 Marburg and Ebola Virus MRNA 3′ Untranslated Regions Contain Negative Regulators of Translation That Are Modulated By ADAR1 Editing
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Abstract: The filovirus family includes deadly pathogens such as Ebola virus (EBOV) and Marburg virus (MARV). A substantial portion of filovirus genomes encode 5′ and 3′ untranslated …		 Sudip Khadka; Caroline G Williams; Joyce Sweeney-Gibbons; Christopher F Basler; Journal of virology 2021-09-09
214 Bats and Viruses: A Death-defying Friendship
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Abstract: Bats have a primeval evolutionary origin and have adopted various survival methods. They have played a central role in the emergence of various viral diseases. The sustenance of a …		 PARAKRITI GUPTA et. al. Virusdisease 2021-09-09
215 Scoping Review on The Impact of Outbreaks on Sexual and Reproductive Health Services: Proposed Frameworks for Pre-, Intra-, and Postoutbreak Situations
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Abstract: Recent experiences from global outbreaks have highlighted the severe disruptions in sexual and reproductive health services that expose women and girls to preventable health …		 Syed Khurram Azmat; Moazzam Ali; Fahad Javaid Siddiqui; Syed Farhan Ali Tirmizi; James Kiarie; BioMed research international 2021-09-08
216 The Methanolic Extract of Perilla Frutescens Robustly Restricts Ebola Virus Glycoprotein-Mediated Entry
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Abstract: Ebola virus (EBOV), one of the most infectious human viruses and a leading cause of viral hemorrhagic fever, imposes a potential public health threat with several recent …		 YU-TING KUO et. al. Viruses 2021-09-08
217 The First 8 Months of COVID-19 Pandemic in Three West African Countries: Leveraging Lessons Learned from Responses to The 2014-2016 Ebola Virus Disease Outbreak
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Abstract: Experience gained from responding to major outbreaks may have influenced the early coronavirus disease-2019 (COVID-19) pandemic response in several countries across Africa. We …		 BENIDO IMPOUMA et. al. Epidemiology and infection 2021-09-08
218 The Rapid, Massive Growth of COVID-19 Authors in The Scientific Literature
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Abstract: We examined the extent to which the scientific workforce in different fields was engaged in publishing COVID-19-related papers. According to Scopus (data cut, 1 August 2021), 210 …		 John P A Ioannidis; Maia Salholz-Hillel; Kevin W Boyack; Jeroen Baas; Royal Society open science 2021-09-07
219 The Nucleoside Antiviral Prodrug Remdesivir in Treating COVID-19 and Beyond with Interspecies Significance
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Abstract: Infectious pandemics result in hundreds and millions of deaths, notable examples of the Spanish Flu, the Black Death and smallpox. The current pandemic, caused by SARS-CoV-2 …		 Daisy Yan; One Hyuk Ra; Bingfang Yan; Animal diseases 2021-09-07
220 [Risk Perception Among Health Professionals in The First Case of Secondary Ebola Infection in Spain. Case Study.]
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Abstract: In 2014, the first case of secondary Ebola infection outside Africa detected in Spain, caused a sense of global threat. This study assess Risk Perception amongst the health …		 Ana Ayuso-Álvarez; Teresa Blasco Hernández; Agustín Benito Llanes; Revista espanola de salud publica 2021-09-07
221 Plant-Based COVID-19 Vaccines: Current Status, Design, and Development Strategies of Candidate Vaccines
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Abstract: The prevalence of the coronavirus disease 2019 (COVID-19) pandemic in its second year has led to massive global human and economic losses. The high transmission rate and the …		 Puna Maya Maharjan; Sunghwa Choe; Vaccines 2021-09-06
222 Optimization of Single Dose VSV-based COVID-19 Vaccination in Hamsters
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Abstract: The ongoing COVID-19 pandemic has resulted in global effects on human health, economic stability, and social norms. The emergence of viral variants raises concerns about the …		 KYLE L OÂ DONNELL et. al. bioRxiv : the preprint server for biology 2021-09-03
223 Optimization of Single Dose VSV-based COVID-19 Vaccination in Hamsters
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Highlight: Here, we demonstrate the immunogenicity and protective efficacy of two vesicular stomatitis virus (VSV)-based vaccines encoding the SARS-CoV-2 spike protein either alone (VSV-SARS2) or in combination with the Ebola virus glycoprotein (VSV-SARS2-EBOV).		 K. L. O’DONNELL et. al. bio.microbiology 2021-09-03
224 Actor-Network Analysis of Community-Based Organisations in Health Pandemics: Evidence from Covid-19 Response in Freetown, Sierra Leone
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Abstract: Freetown is confronted with health-related risks that are compounded by rapid unplanned urbanisation and weak capacities of local government institutions. Addressing such …		 LOUIS KUSI FRIMPONG et. al. Disasters 2021-09-03
225 Ebola Virus Protein VP40 Binding to Sec24c for Transport to The Plasma Membrane
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Abstract: Outbreaks of the Ebola virus (EBOV) continue to occur and while a vaccine and treatment are now available, there remains a dearth of options for those who become sick with EBOV …		 NISHA BHATTARAI et. al. Proteins 2021-09-03
226 Plant-based Vaccine Research Development Against Viral Diseases with Emphasis on Ebola Virus Disease: A Review Study
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Abstract: Ebola virus infection results in the fast onset of severe acute haemorrhagic fever with high mortality. The Ebola virus is labelled as a category A pathogen. Vaccines against the …		 Satyajit Tripathy; Barsha Dassarma; Manojit Bhattacharya; Motlalepula Gilbert Matsabisa; Current opinion in pharmacology 2021-09-01
227 Correction To: Partnership for Research on Ebola VACcination (PREVAC): Protocol of A Randomized, Double-blind, Placebo-controlled Phase 2 Clinical Trial Evaluating Three Vaccine Strategies Against Ebola in Healthy Volunteers in Four West African Countries
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 MOSES BADIO et. al. Trials 2021-09-01
228 Imperfect Diagnosis: The Truncated Legacies of Zika Testing
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Abstract: When the Zika virus burst onto the international scene in the second half of 2015, the development of diagnostic tools was seen as an urgent global health priority. Diagnostic …		 Koichi Kameda; Ann H Kelly; Javier Lezaun; Ilana Löwy; Social studies of science 2021-08-31
229 Conserved Immunogenic Peptides of Ebola Glycoprotein Elicit Immune Response in Human Peripheral Blood Mononuclear Cells
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Abstract: In the past 45 years, ebolaviruses have periodically caused epidemics on the African continent. In December 2019, approval of a recombinant vector-based EBOV vaccine, named …		 Sahil Jain; Manoj Baranwal; Microbiology and immunology 2021-08-31
230 A Mixed-methods Investigation to Understand and Improve The Scaled-up Infection Prevention and Control in Primary Care Health Facilities During The Ebola Virus Disease Epidemic in Sierra Leone
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Abstract: The 2014-2015 Ebola epidemic in West Africa became a humanitarian crisis that exposed significant gaps in infection prevention and control (IPC) capacity in primary care …		 Lara Shiu-Yi Ho; Ruwan Ratnayake; Rashid Ansumana; Hannah Brown; BMC public health 2021-08-31
231 Potential Test-negative Design Study Bias in Outbreak Settings: Application to Ebola Vaccination in Democratic Republic of Congo
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Abstract: Infectious disease outbreaks present unique challenges to study designs for vaccine evaluation. Test-negative design (TND) studies have previously been used to estimate vaccine …		 Carl A B Pearson; W John Edmunds; Thomas J Hladish; Rosalind M Eggo; International journal of epidemiology 2021-08-30
232 Review: Insights on Current FDA-Approved Monoclonal Antibodies Against Ebola Virus Infection
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Abstract: The unprecedented 2013-2016 West Africa Ebola outbreak accelerated several medical countermeasures (MCMs) against Ebola virus disease (EVD). Several investigational products (IPs) …		 Olivier Tshiani Mbaya; Philippe Mukumbayi; Sabue Mulangu; Frontiers in immunology 2021-08-30
233 The Good, The Bad and The Ugly of Testicular Immune Regulation: A Delicate Balance Between Immune Function and Immune Privilege
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Abstract: The testis is one of several immune privilege sites. These sites are necessary to decrease inflammation and immune responses that could be damaging to the host. For example, …		 Gurvinder Kaur; Kandis Wright; Saguna Verma; Allan Haynes; Jannette M Dufour; Advances in experimental medicine and biology 2021-08-28
234 Therapeutics Development for Ebola Virus Disease: A Recent Scenario
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Abstract: The Ebola virus disease is a deadly pathogenic disease caused by the Ebola virus. It has been observed that this disease causes a high case-fatality rate. Several species of this …		 Chiranjib Chakraborty; Current opinion in pharmacology 2021-08-28
235 Direct and Quantitative Capture of Viable Bacteriophages from Experimentally Contaminated Indoor Air: A Model for The Study of Airborne Vertebrate Viruses Including SARS-CoV-2
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Abstract: The air indoors has profound health implications as it can expose us to pathogens, allergens and particulates either directly or via contaminated surfaces. There is, therefore, an …		 Bahram Zargar; Syed A Sattar; Richard Kibbee; Joseph Rubino; M Khalid Ijaz; Journal of applied microbiology 2021-08-28
236 Application of Pseudotyped Virus Particles to Monitor Ebola Virus and SARS-CoV-2 Viral Entry in Human Cell Lines
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Abstract: Experimental work on highly pathogenic viruses such as Ebola virus (EBOV) and severe acute respiratory syndrome coronavirus-2 requires high-level biosafety facilities. Here, we …		 Madeleine Eichler; Ebru Aksi; Josef Pfeilschifter; Gergely Imre; STAR protocols 2021-08-27
237 Marta Lado-Ebola, HIV, Sexual Health and More
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 Tony Kirby; The Lancet. Infectious diseases 2021-08-27
238 Vesicular Stomatitis Virus: From Agricultural Pathogen to Vaccine Vector
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Abstract: Vesicular stomatitis virus (VSV), which belongs to the genus of the family , is a well studied livestock pathogen and prototypic non-segmented, negative-sense RNA virus. Although …		 GUODONG LIU et. al. Pathogens (Basel, Switzerland) 2021-08-27
239 GEViTRec: Data Reconnaissance Through Recommendation Using A Domain-Specific Visualization Prevalence Design Space
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Abstract: Genomic Epidemiology (genEpi) is a branch of public health that uses many different data types including tabular, network, genomic, and geographic, to identify and contain …		 Anamaria Crisan; Shannah Elizabeth Fisher; Jennifer L Gardy; Tamara Munzner; IEEE transactions on visualization and computer graphics 2021-08-27
240 An Overview of The Preclinical Discovery and Development of Remdesivir for The Treatment of Coronavirus Disease 2019 (COVID-19)
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Abstract: Remdesivir (RDV) is an inhibitor of the viral RNA-dependent RNA polymerases that are active in some RNA viruses, including the Ebola virus and zoonotic coronaviruses. When severe …		 PASQUALE PAGLIANO et. al. Expert opinion on drug discovery 2021-08-27
241 Characterization of An Anti-Ebola Virus Hyperimmune Globulin Derived from Convalescent Plasma
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Abstract: Convalescent plasma has been used to treat many viral diseases including Ebola. The manufacture of a purified anti-Ebola virus (EBOV) intravenous immunoglobulin (IVIG) from pooled …		 JONATHAN M CIENCEWICKI et. al. The Journal of infectious diseases 2021-08-27
242 [Ebola Re-emergence in The Context of Covid-19]
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Abstract: Ebola is the most vicious virus in Africa. International organisations have worked to contain the various outbreaks and a vaccine is being administered to the population. This …		 Adélie Oger; Actualites pharmaceutiques 2021-08-26
243 A Naturally Occurring Polymorphism in The Base of Sudan Virus Glycoprotein Decreases Glycoprotein Stability in A Species-Dependent Manner
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Abstract: Sudan virus (SUDV) is one of five filoviruses that compose the genus that has been responsible for episodic outbreaks in Central Africa. While the SUDV glycoprotein (GP) structure …		 NICHOLAS J LENNEMANN et. al. Journal of virology 2021-08-25
244 Cross-Neutralisation of Novel Bombali Virus By Ebola Virus Antibodies and Convalescent Plasma Using An Optimised Pseudotype-Based Neutralisation Assay
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Abstract: Ebolaviruses continue to pose a significant outbreak threat, and while Ebola virus (EBOV)-specific vaccines and antivirals have been licensed, efforts to develop candidates …		 EMMA M BENTLEY et. al. Tropical medicine and infectious disease 2021-08-25
245 Mapping of Ebola Virus Spillover: Suitability and Seasonal Variability at The Landscape Scale
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Highlight: We used a Geographic Information System-based multicriteria evaluation (GIS-MCE), a knowledge-based approach, to identify areas suitable for Ebola virus spillover to humans in regions of Guinea, Congo and Gabon where Ebola viruses already emerged.		 LARISA LEE-CRUZ et. al. arxiv-q-bio.PE 2021-08-24
246 Ebola and COVID-19 in Democratic Republic of Congo: Grappling with Two Plagues at Once
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Abstract: In February 2021, a new Ebola virus disease outbreak was confirmed amid the COVID-19 pandemic in the Democratic Republic of Congo. Although the country has successfully contained …		 FATIMA MUHAMMAD ASAD KHAN et. al. Tropical medicine and health 2021-08-24
247 Training Health Workers at Scale in Nigeria to Fight COVID-19 Using The InStrat COVID-19 Tutorial App: An E-health Interventional Study
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Abstract: Health worker training is an essential component of epidemic control; rapid delivery of such training is possible in low-middle income countries with digital platforms. Based on …		 AKANINYENE OTU et. al. Therapeutic advances in infectious disease 2021-08-23
248 Perceptions of Ebola Virus Disease Among The Bambuti Hunter Group: A Mixed-methods Study
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Abstract: The second largest Ebola virus disease (EVD) epidemic occurred in the Democratic Republic of the Congo (DRC) from 2018-20. The Bambuti, a hunter population in the Ituri Forest of …		 Ella M E Forgie; Kasereka Masumbuko Claude; Michael T Hawkes; Pathogens and global health 2021-08-22
249 Interruption of Tuberculosis Detection and Care During The Ebola Virus Disease Epidemic (2014-2015) in Liberia: Time-series Analyses for 2013-2017
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Abstract: Interrupted time-series analyses, using 5 years of routinely collected health information system data, were conducted to estimate the magnitude of impact of the 2014-2015 Ebola …		 KEITH L GRAY et. al. International journal of infectious diseases : IJID : … 2021-08-22
250 The Microbiota-related Coinfections in COVID-19 Patients: A Real Challenge
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Abstract: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of ongoing global pandemic of coronavirus disease 2019 (COVID-19), has infected millions of people …		 RANJAN K MOHAPATRA et. al. Beni-Suef University journal of basic and applied sciences 2021-08-21
251 The Epidemiology of Emerging Infectious Diseases and Pandemics
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Abstract: The spectrum of human pathogens and the infectious diseases they cause is continuously changing through evolution, selection and changes in the way human populations interact with …		 H Rogier van Doorn; Medicine (Abingdon, England : UK ed.) 2021-08-21
252 The Rapid, Massive Growth of COVID-19 Authors in The Scientific Literature
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Highlight: We examined the extent to which the scientific workforce in different fields was engaged in publishing COVID-19-related papers.		 J. Ioannidis; M. Salholz-Hillel; K. Boyack; J. Baas; bio.scientific-communication-and-education 2021-08-21
253 Modulation of Immune Response in Ebola Virus Disease
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Abstract: Ebola virus disease targets and destroys immune cells, including macrophages and dendritic cells, leading to impairment of host response. After infection, a combination of …		 GOUTAM BANERJEE et. al. Current opinion in pharmacology 2021-08-20
254 [SARS-CoV-2 Vaccines and Reaction of The Immune System. Can the epidemic Spread of The Virus Be Prevented By Vaccination?]
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Abstract: Since the end of 2019 a new coronavirus, SARS-CoV-2, first identified in Wuhan, China, is spreading around the world partially associated with a high death toll. Besides hygienic …		 Jonas Schmidt; Frithjof Blessing; Lutz Gürtler; Deutsche medizinische Wochenschrift (1946) 2021-08-20
255 Molecular Dynamics Simulations Reveal The Interaction Fingerprint of Remdesivir Triphosphate Pivotal in Allosteric Regulation of SARS-CoV-2 RdRp
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Abstract: The COVID-19 pandemic has now strengthened its hold on human health and coronavirus’ lethal existence does not seem to be going away soon. In this regard, the optimization of …		 Mitul Srivastava; Lovika Mittal; Anita Kumari; Shailendra Asthana; Frontiers in molecular biosciences 2021-08-20
256 The Ebola Virus Interferon Antagonist VP24 Undergoes Active Nucleocytoplasmic Trafficking
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Abstract: Viral interferon (IFN) antagonist proteins mediate evasion of IFN-mediated innate immunity and are often multifunctional, with distinct roles in viral replication. The Ebola virus …		 Angela R Harrison; Cassandra T David; Stephen M Rawlinson; Gregory W Moseley; Viruses 2021-08-19
257 Pandemic, Epidemic, Endemic: B Cell Repertoire Analysis Reveals Unique Anti-viral Responses to SARS-CoV-2, Ebola and Respiratory Syncytial Virus
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Highlight: Detailed compositional and lineage analysis of long read IGH repertoire sequencing, combining examples of pandemic, epidemic and endemic viral infections with control and vaccination samples, demonstrates general responses including increased use of IGHV4-39 in both EBOV and COVID-19 infection cohorts.		 A. STEWART et. al. bio.immunology 2021-08-19
258 Ivory Coast Rolls Out Ebola Vaccine After First Confirmed Case Since 1994
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 Luke Taylor; BMJ (Clinical research ed.) 2021-08-18
259 Global Research Activity on Health System Preparedness Against Viral Infectious Disease Outbreaks
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Abstract: The present study aimed to give an overview of research publications on health system preparedness against viral infectious disease outbreaks. A bibliometric method was …		 Waleed M Sweileh; Disaster medicine and public health preparedness 2021-08-18
260 Health Facilities’ Readiness for Safe Surgical Care Provision in Uganda and The Eastern Democratic Republic of Congo During Ebola and COVID-19 Era
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Abstract: This study aimed to assess health facilities’ readiness to provide safe surgical care during Ebola and COVID-19 era in Uganda and in the Eastern DR Congo. A cross-sectional study …		 FRANCK KATEMBO SIKAKULYA et. al. BMC health services research 2021-08-18
261 Atoltivimab/maftivimab/odesivimab (Inmazeb) Combination to Treat Infection Caused By Zaire Ebolavirus
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Abstract: Zaire ebolavirus has been responsible for several catastrophic outbreaks with a high mortality rate. Unfortunately, there were no approved therapies or vaccines to treat or …		 D Saxena; G Kaul; A Dasgupta; S Chopra; Drugs of today (Barcelona, Spain : 1998) 2021-08-18
262 Recombinant Protein Filovirus Vaccines Protect Cynomolgus Macaques From Ebola, Sudan, and Marburg Viruses
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Abstract: Ebola (EBOV), Marburg (MARV) and Sudan (SUDV) viruses are the three filoviruses which have caused the most fatalities in humans. Transmission from animals into the human …		 AXEL T LEHRER et. al. Frontiers in immunology 2021-08-18
263 Pandemic Risk Management: Resources Contingency Planning and Allocation
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Abstract: The repeated history of pandemics, such as SARS, H1N1, Ebola, Zika, and COVID-19, has shown that pandemic risk is inevitable. Extraordinary shortages of medical resources have …		 Xiaowei Chen; Wing Fung Chong; Runhuan Feng; Linfeng Zhang; Insurance, mathematics & economics 2021-08-17
264 Delayed Disease in Cynomolgus Macaques Exposed to Ebola Virus By An Intranasal Route
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Abstract: Ebola virus remains a significant public health concern due to high morbidity and mortality rates during recurrent outbreaks in endemic areas. Therefore, the development of …		 SARA C JOHNSTON et. al. Frontiers in immunology 2021-08-16
265 Remdesivir for The Treatment of COVID 19: Review of The Pharmacological Properties, Safety and Clinical Effectiveness
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Abstract: Remdesivir is a nucleoside analog that inhibits viral RNA replication by blocking RNA-dependent RNA polymerase. First developed and tested during the Ebola epidemic, repurposed, …		 Ashesha Mechineni; Hagar Kassab; Rajapriya Manickam; Expert opinion on drug safety 2021-08-16
266 Psychology and The Threat of Contagion: Feeling Vulnerable to A Disease Moderates The Link Between Xenophobic Thoughts and Support for Ingroup-Protective Actions
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Abstract: The widespread threat of contagious disease disrupts not only everyday life but also psychological experience. Building on findings regarding xenophobic responses to contagious …		 Heejung S Kim; Kimin Eom; Roxie Chuang; David K Sherman; Personality & social psychology bulletin 2021-08-16
267 Barriers and Opportunities for Sustainable Hand Hygiene Interventions in Rural Liberian Hospitals
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Abstract: Hand hygiene is central to hospital infection control. During the 2014-2016 West Africa Ebola virus disease epidemic in Liberia, gaps in hand hygiene infrastructure and health …		 LUCY K TANTUM et. al. International journal of environmental research and public … 2021-08-14
268 [Challenges in The Management of Haemorrhagic Fevers: Ebola Virus Disease Experience in The North Kivu Province and Ituri Province (Democratic Republic of Congo) and The Importance of Early Diagnosis]
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Abstract: Ebola virus disease is a serious, often fatal disease whose case-fatality rate can be 90%. Our short-term goal is to create awareness on Ebola virus signs and to encourage early …		 CRISS KOBA MJUMBE et. al. The Pan African medical journal 2021-08-13
269 Measuring The Scientific Effectiveness of Contact Tracing: Evidence from A Natural Experiment
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Abstract: Contact tracing has for decades been a cornerstone of the public health approach to epidemics, including Ebola, severe acute respiratory syndrome, and now COVID-19. It has not yet …		 Thiemo Fetzer; Thomas Graeber; Proceedings of the National Academy of Sciences of the … 2021-08-13
270 Transcriptional Analysis of Infection With Early or Late Isolates From The 2013-2016 West Africa Ebola Virus Epidemic Does Not Suggest Attenuated Pathogenicity As A Result of Genetic Variation
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Abstract: The 2013-2016 West Africa Ebola virus (EBOV) epidemic caused by the EBOV-Makona isolate is the largest and longest recorded to date. It incurred over 28,000 infections and ∼11,000 …		 Kevin J Maroney; Amanda N Pinski; Andrea Marzi; Ilhem Messaoudi; Frontiers in microbiology 2021-08-13
271 Zoonotic Risk Factors Associated with Seroprevalence of Ebola Virus GP Antibodies in The Absence of Diagnosed Ebola Virus Disease in The Democratic Republic of Congo
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Abstract: Ebola virus (EBOV) is a zoonotic filovirus spread through exposure to infected bodily fluids of a human or animal. Though EBOV is capable of causing severe disease, referred to as …		 ANNA BRATCHER et. al. PLoS neglected tropical diseases 2021-08-12
272 Novel Quinolone Derivatives Targeting Human Dihydroorotate Dehydrogenase Suppress Ebola Virus Infection in Vitro
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Abstract: Ebola virus (EBOV) has emerged as a significant public health concern since the 2013-2016 outbreak in West Africa. Currently, no effective antiviral treatments have been approved …		 MINGLI GONG et. al. Antiviral research 2021-08-12
273 Mixed-methods Assessment of Health and Mental Health Characteristics and Barriers to Healthcare for Ebola Survivors in Beni, Butembo and Katwa Health Zones of The Democratic Republic of Congo
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Abstract: Health and mental health characteristics of all respondents, barriers to accessing health and mental health services and the characteristics and those most at risk for mental …		 Lynn Lieberman Lawry; Nancy Stroupe Kannappan; Covadonga Canteli; William Clemmer; BMJ open 2021-08-11
274 Bundibugyo Ebolavirus Survival Is Associated with Early Activation of Adaptive Immunity and Reduced Myeloid-Derived Suppressor Cell Signaling
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Abstract: Ebolaviruses Bundibugyo virus (BDBV) and Ebola virus (EBOV) cause fatal hemorrhagic disease in humans and nonhuman primates. While the host response to EBOV is well characterized, …		 COURTNEY WOOLSEY et. al. mBio 2021-08-10
275 Repurposing Psychotropic Agents for Viral Disorders: Beyond Covid
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Abstract: Recent reports have highlighted the possible role of the antipsychotic chlorpromazine and the antidepressant fluvoxamine as anti-coronavirus disease 2019 (COVID-19) agents. The …		 Shea R Golden; Donald L Rosenstein; Tom Belhorn; Julie Blatt; Assay and drug development technologies 2021-08-10
276
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Abstract: The objective of this study was to identify the factors that influenced the poor performance of the Community Observatory on Access to Health Services (OCASS) project during its …		 Thierno Oumar Fofana; Werner Soors; Abdoulaye Sow; Alexandre Delamou; Bruno Marchal; Sante publique (Vandoeuvre-les-Nancy, France) 2021-08-10
277 Identification and Characterization of Defective Viral Genomes in Ebola Virus-Infected Rhesus Macaques
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Abstract: Ebola virus (EBOV), of the family , is an RNA virus that can cause a hemorrhagic fever with a high mortality rate. Defective viral genomes (DVGs) are truncated genomes that have …		 REBECCA I JOHNSON et. al. Journal of virology 2021-08-10
278 Reservoir Host Studies of Lloviu Virus: First Isolation, Sequencing and Serology in Schreiber’s Bats in Europe
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Highlight: We present data on the natural infection and seropositivity of Schreiber’s bats and provide novel LLOV genomic sequence information from a bat host and an arthropod parasite.		 G. KEMENESI et. al. bio.microbiology 2021-08-10
279 Comparison of The Efficacy of Disinfectant Pre-impregnated Wipes for Decontaminating Stainless Steel Carriers Experimentally Inoculated With Ebola Virus and Vesicular Stomatitis Virus
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Abstract: The authors evaluated four disinfectant pre-impregnated wipes (DPW) for efficacy against Ebola virus Makona variant (EBOV) and vesicular stomatitis virus (VSV), Indiana serotype. …		 TODD A CUTTS et. al. Frontiers in public health 2021-08-10
280 Maf/ham1-like Pyrophosphatases of Non-canonical Nucleotides Are Host-specific Partners of Viral RNA-dependent RNA Polymerases
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Highlight: Here, using an infectious cDNA clone and reverse genetics, we demonstrate that UCBSV requires the ITPase activity in cassava, but not in the model plant Nicotiana benthamiana.		 A. A. VALLI et. al. bio.molecular-biology 2021-08-09
281 Importance of Community-Level Interventions During The COVID-19 Pandemic: Lessons from Sub-Saharan Africa
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Abstract: Community-level strategies are important in ensuring adequate control of disease outbreaks especially in sub-Saharan African countries. Learning from public health responses to …		 AYOMIDE OWOYEMI et. al. The American journal of tropical medicine and hygiene 2021-08-09
282 Single Dose RVSVΔG-JUNVGP Vaccine Protects Guinea Pigs Against Lethal Junin Virus Challenge
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Abstract: Junin virus (JUNV) is a pathogen of biodefense importance due to its potential for aerosol transmission and mortality rates reaching 30%. Currently, there are no JUNV vaccines …		 TERESA E SORVILLO et. al. NPJ vaccines 2021-08-09
283 A Linear Noise Approximation for Stochastic Epidemic Models Fit to Partially Observed Incidence Counts
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Abstract: Stochastic epidemic models (SEMs) fit to incidence data are critical to elucidating outbreak dynamics, shaping response strategies, and preparing for future epidemics. SEMs …		 Jonathan Fintzi; Jon Wakefield; Vladimir N Minin; Biometrics 2021-08-09
284 Use of Iris Scanning for Biometric Recognition of Healthy Adults Participating in An Ebola Vaccine Trial in The Democratic Republic of The Congo: Mixed Methods Study
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Abstract: A partnership between the University of Antwerp and the University of Kinshasa implemented the EBOVAC3 clinical trial with an Ebola vaccine regimen administered to health care …		 TRÉSOR ZOLA MATUVANGA et. al. Journal of medical Internet research 2021-08-09
285 Anti-Ebola: An Initiative to Predict Ebola Virus Inhibitors Through Machine Learning
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Abstract: Ebola virus is a deadly pathogen responsible for a frequent series of outbreaks since 1976. Despite various efforts from researchers worldwide, its mortality and fatality are …		 Akanksha Rajput; Manoj Kumar; Molecular diversity 2021-08-06
286 Enabling Artificial Intelligence for Genome Sequence Analysis of COVID-19 and Alike Viruses
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Abstract: Recent pandemic of COVID-19 (Coronavirus) caused by severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) has been growing lethally with unusual speed. It has infected …		 Imran Ahmed; Gwanggil Jeon; Interdisciplinary sciences, computational life sciences 2021-08-06
287 COVID-19, Ebola Virus Disease, and Nipah Virus Infection Reclassification As Novel Acute Immune Dysrhythmia Syndrome (n-AIDS): Potential Crucial Role for Immunomodulators
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Abstract: In this manuscript, COVID-19, Ebola virus disease, Nipah virus infection, SARS, and MERS are suggested to be considered for a novel immunological reclassification as acute onset …		 Mina T Kelleni; Immunologic research 2021-08-06
288 Agent-based Analysis of Contagion Events According to Sourcing Locations
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Abstract: The first human infected with the Covid-19 virus was traced to a seafood market in Wuhan, China. Research shows that there are comparable types of viruses found in different and …		 Mijat Kustudic; Ben Niu; Qianying Liu; Scientific reports 2021-08-06
289 Development and Implementation of The Ebola Exposure Window Calculator: A Tool for Ebola Virus Disease Outbreak Field Investigations
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Abstract: During an Ebola virus disease (EVD) outbreak, calculating the exposure window of a confirmed case can assist field investigators in identifying the source of infection and …		 AMY WHITESELL et. al. PloS one 2021-08-05
290 Genome Structure and Genetic Diversity in The Ebola Virus
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Abstract: Ebola is a deadly pathogen responsible for Ebola virus disease, first came to prominence in the year 1976. This rapidly evolving virus imposed a serious threat to the human …		 Sanmitra Ghosh; Abinit Saha; Saikat Samanta; Rudra P Saha; Current opinion in pharmacology 2021-08-04
291 Reviewing Antiviral Research Against Viruses Causing Human Diseases – A Structure Guided Approach
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Abstract: The littlest of all the pathogens, viruses have continuously been the foremost strange microorganisms to consider. Viral Infections can cause extreme sicknesses as archived by the …		 Arunima Sikdar; Rupali Gupta; Evzen Boura; Current molecular pharmacology 2021-08-04
292 Laboratory Diagnosis of Tropical Infections
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Abstract: (1) Blood culture is the gold standard for the diagnosis of bacterial infections. (2) Bone marrow culture is more sensitive than blood culture even in patients with enteric fever …		 Shaoli Basu; Anjali Shetty; Indian journal of critical care medicine : peer-reviewed, … 2021-08-04
293 Ecology of Ebolaviruses
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Abstract: Africa is becoming known for the emergence and re-emergence of Ebola virus. The virus, which was initially restricted to East and Central Africa, is now emerging in West Africa. …		 Elijah Ige Ohimain; Current opinion in pharmacology 2021-08-03
294 Suitability of Google Trends™ for Digital Surveillance During Ongoing COVID-19 Epidemic: A Case Study from India
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Abstract: Digital surveillance has shown mixed results as a supplement to traditional surveillance. Google Trends™ (GT) (Google, Mountain View, CA, United States) has been used for digital …		 Parmeshwar Satpathy; Sanjeev Kumar; Pankaj Prasad; Disaster medicine and public health preparedness 2021-08-03
295 Impact of Poor Disease Surveillance System on COVID-19 Response in Africa: Time to Rethink and Rebuilt
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Abstract: Infectious disease outbreaks have long posed a public health threat, especially in Africa, where the incidence of infectious outbreaks has risen exponentially. Although, Africa …		 ABDULLAHI TUNDE ABORODE et. al. Clinical epidemiology and global health 2021-08-03
296 Recombinant Lloviu Virus As A Model to Study Inaccessible Zoonotic Viruses
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Highlight: We leveraged these data to generate recombinant full-length LLOV clones and rescue infectious virus.		 A. J. HUME et. al. bio.microbiology 2021-08-02
297 Non-canonical Proline-tyrosine Interactions with Multiple Host Proteins Regulate Ebola Virus Infection
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Abstract: The Ebola virus VP30 protein interacts with the viral nucleoprotein and with host protein RBBP6 via PPxPxY motifs that adopt non-canonical orientations, as compared to other …		 JYOTI BATRA et. al. The EMBO journal 2021-08-02
298 Global Health Security As It Pertains to Zika, Ebola, and COVID-19
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Abstract: Due to the impact of the COVID-19 pandemic this past year, we have witnessed a significant acceleration in the science, technology, and policy of global health security. This …		 Jaspreet Pannu; Michele Barry; Current opinion in infectious diseases 2021-08-02
299 Analytical Estimation of Data-Motivated Time-Dependent Disease Transmission Rate: An Application to Ebola and Selected Public Health Problems
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Abstract: Obtaining reasonable estimates for transmission rates from observed data is a challenge when using mathematical models to study the dynamics of ?infectious? diseases, like Ebola. …		 ANUJ MUBAYI et. al. Tropical medicine and infectious disease 2021-07-31
300 Deciphering The Impact of Novel Coronavirus Pandemic on Agricultural Sustainability, Food Security, and Socio-economic Sectors-a Review
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Abstract: The Spanish flu, Asian flu, Hong Kong flu, HIV/AIDS, SARS, Ebola, and Swine flu, among others, have had a significant impact on agriculture, education, the economy, and human …		 Mehvish Mumtaz; Nazim Hussain; Zulqarnain Baqar; Saima Anwar; Muhammad Bilal; Environmental science and pollution research international 2021-07-31
301 Simultaneous Detection of Ebola Virus and Pathogens Associated With Hemorrhagic Fever By An Oligonucleotide Microarray
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Abstract: Ebola virus infection causes severe hemorrhagic fever, and its mortality rates varied from 25 to 90% in the previous outbreaks. The highly infectious and lethal nature of this …		 WENWU YAO et. al. Frontiers in microbiology 2021-07-30
302 A SEIR Model with Memory Effects for The Propagation of Ebola-like Infections and Its Dynamically Consistent Approximation
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Abstract: We present and analyze a nonstandard numerical method to solve an epidemic model with memory that describes the propagation of Ebola-type diseases. The epidemiological system …		 ZAFAR IQBAL et. al. Computer methods and programs in biomedicine 2021-07-29
303 Ebola Outbreaks: A Stress Test of The Preparedness of Medicines Regulatory Systems for Public Health Crises
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Abstract: In a globalized world, infectious diseases of international concern are inevitable. When they (re-)emerge, the regulatory system works towards mitigating their impact. Ebola …		 Rafael Amaral; Carla Torre; João Rocha; Bruno Sepodes; Drug discovery today 2021-07-28
304 Ebola Virus Requires Phosphatidylserine Scrambling Activity for Efficient Budding and Optimal Infectivity
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Abstract: Ebola virus (EBOV) attaches to target cells using two categories of cell surface receptors: C-type lectins and phosphatidylserine (PS) receptors. PS receptors typically bind to …		 MARISSA D ACCIANI et. al. Journal of virology 2021-07-28
305 Remember Ebola: Stop Mass Death in Africa
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 Mosoka Fallah; Nature 2021-07-28
306 Recent Developments and Strategies of Ebola Virus Vaccines
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Abstract: The Filovirus family member, Ebola virus (EBOV), is a highly infectious pathogen responsible for viral hemorrhagic fever. EBOV has a fatality rate in the range 50%-90% in …		 Ashish Ranjan Sharma; Yeon-Hee Lee; Sudarshini Nath; Sang-Soo Lee; Current opinion in pharmacology 2021-07-27
307 Remdesivir Analogs Against SARS-CoV-2 RNA-dependent RNA Polymerase
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Abstract: The COVID-19 pandemic has already taken many lives but is still continuing its spread and exerting jeopardizing effects. This study is aimed to find the most potent ligands from …		 SINTHYIA AHMED et. al. Journal of biomolecular structure & dynamics 2021-07-27
308 Immunoinformatics Aided Design of Peptide-based Vaccines Against Ebolaviruses
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Abstract: Ebolaviruses are at the forefront of emerging viruses and present a very perceptible threat to global peace and harmony. In the last decade, Ebola virus disease has claimed more …		 Sahil Jain; Manoj Baranwal; Vitamins and hormones 2021-07-27
309 A Yeast BiFC-seq Method for Genome-wide Interactome Mapping
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Abstract: Genome-wide physical protein-protein interaction (PPI) mapping remains a major challenge for current technologies. Here, we report a high-efficiency yeast bimolecular fluorescence …		 LIMIN SHANG et. al. Genomics, proteomics & bioinformatics 2021-07-24
310 The Rise of SARS-CoV-2 Variants and The Role of Convalescent Plasma Therapy for Management of Infections
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Abstract: Novel therapies for the treatment of COVID-19 are continuing to emerge as the SARS-Cov-2 pandemic progresses. PCR remains the standard benchmark for initial diagnosis of COVID-19 …		 MOHAMED MOUBARAK et. al. Life (Basel, Switzerland) 2021-07-23
311 Computational Identification of Repurposed Drugs Against Viruses Causing Epidemics and Pandemics Via Drug-target Network Analysis
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Abstract: Viral epidemics and pandemics are considered public health emergencies. However, traditional and novel antiviral discovery approaches are unable to mitigate them in a timely …		 Akanksha Rajput; Anamika Thakur; Amber Rastogi; Shubham Choudhury; Manoj Kumar; Computers in biology and medicine 2021-07-23
312 ‘Learn from The Lessons and Don’t Forget Them’: Identifying Transferable Lessons for COVID-19 from Meningitis A, Yellow Fever and Ebola Virus Disease Vaccination Campaigns
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Abstract: COVID-19 vaccines are now being distributed to low- and middle-income countries (LMICs), with global urgency surrounding national vaccination plans. LMICs have significant …		 JULIE COLLINS et. al. BMJ global health 2021-07-19
313 Learn from The Lessons and Don’t Forget Them: Identifying Transferable Lessons for COVID-19 from Meningitis A, Yellow Fever, and Ebola Virus Disease Vaccination Campaigns
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Highlight: Methods: We conducted a rapid literature review and 24 semi-structured interviews with technical experts who had direct implementation experience with the selected vaccines in Africa and South America.		 J. COLLINS et. al. med.public-and-global-health 2021-07-19
314 The Establishment and Application of Mobile Electronic Surveillance System for Infectious Diseases with The Help of China – Sierra Leone, 2016-Present
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Abstract: Infectious disease surveillance has long been a challenge for low-income countries like Sierra Leone. Traditional approaches based on paper and Short Message Service (SMS) were …		 GUANGYU ZHAO et. al. China CDC weekly 2021-07-19
315 What Effect Might Border Screening Have on Preventing Importation of COVID-19 Compared with Other Infections? A Modelling Study
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Highlight: In this paper, we describe a simple Monte Carlo based model that incorporates the epidemiology of COVID-19 to investigate the potential benefit of requiring all travellers to undergo thorough screening upon arrival.		 D. Bays; E. Bennett; T. Finnie; med.epidemiology 2021-07-17
316 Epidemics, Pandemics, and Social Conflict: Lessons from The Past and Possible Scenarios for COVID-19
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Abstract: Since COVID-19 broke out, there has been renewed interest in understanding the economic and social dynamics of historical and more recent epidemics and pandemics, from the plagues …		 Remi Jedwab; Amjad M Khan; Jason Russ; Esha D Zaveri; World development 2021-07-17
317 Construction and Evaluation of DNA Vaccine Encoding Ebola Virus Glycoprotein Fused with Lysosome-associated Membrane Protein
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Abstract: Ebola virus (EBOV) of the genus Ebolavirus belongs to the family Filoviridae, which cause disease in both humans and non-human primates. Zaire Ebola virus accounts for the highest …		 YANG LIU et. al. Antiviral research 2021-07-16
318 Poly-l-lysine Glycoconjugates Inhibit DC-SIGN-mediated Attachment of Pandemic Viruses
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Abstract: The C-type lectin receptor DC-SIGN mediates interactions with envelope glycoproteins of many viruses such as SARS-CoV-2, ebola, and HIV and contributes to virus internalization …		 JONATHAN CRAMER et. al. ChemMedChem 2021-07-16
319 CryoEM Structure of The Nipah Virus Nucleocapsid Assembly
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Abstract: Nipah and its close relative Hendra are highly pathogenic zoonotic viruses, storing their ssRNA genome in a helical nucleocapsid assembly formed by the N protein, a major viral …		 De-Sheng Ker; Huw T Jenkins; Sandra J Greive; Alfred A Antson; PLoS pathogens 2021-07-16
320 Proteo-Genomic Analysis Identifies Two Major Sites of Vulnerability on Ebolavirus Glycoprotein for Neutralizing Antibodies in Convalescent Human Plasma
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Abstract: Three clinically relevant ebolaviruses – Ebola (EBOV), Bundibugyo (BDBV), and Sudan (SUDV) viruses, are responsible for severe disease and occasional deadly outbreaks in Africa. …		 PAVLO GILCHUK et. al. Frontiers in immunology 2021-07-16
321 Mapping The Global Research Output on Ebola Vaccine from Research Indexed in Web of Science and Scopus: A Comprehensive Bibliometric Analysis
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Abstract: : The Ebola Virus outbreak in Africa is believed to be one of the deadliest viral infections that causes severe hemorrhagic fever in human and nonhuman primates, which has …		 TOSIN YINKA AKINTUNDE et. al. Human vaccines & immunotherapeutics 2021-07-16
322 Immunogenicity and Safety of Ebola Virus Vaccines in Healthy Adults: A Systematic Review and Network Meta-analysis
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Abstract: Clinical development of Ebola virus vaccines (EVV) was accelerated by the West African Ebola virus epidemic which remains the deadliest in history. To compare and rank the EVV …		 ALHASSANE DIALLO et. al. Human vaccines & immunotherapeutics 2021-07-16
323 A Snapshot of Poverty, Diseases and War – The Democratic Republic of The Congo
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Abstract: DRC’s fight with the EVD (Ebola Virus Disease) was just settling when WHO declared COVID-19 to be a Public Health Emergency of International Concern (PHEIC) on March 12, 2020. …		 Shibu Sasidharan; Harpreet Singh Dhillon; Disaster medicine and public health preparedness 2021-07-15
324 Cysteine Mutations in The Ebolavirus Matrix Protein VP40 Promote Phosphatidylserine Binding By Increasing The Flexibility of A Lipid-Binding Loop
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Abstract: Ebolavirus (EBOV) is a negative-sense RNA virus that causes severe hemorrhagic fever in humans. The matrix protein VP40 facilitates viral budding by binding to lipids in the host …		 KRISTEN A JOHNSON et. al. Viruses 2021-07-15
325 Immunopathogenesis of Different Emerging Viral Infections: Evasion, Fatal Mechanism, and Prevention
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Abstract: Different emerging viral infections may emerge in different regions of the world and pose a global pandemic threat with high fatality. Clarification of the immunopathogenesis of …		 Betsy Yang; Kuender D Yang; Frontiers in immunology 2021-07-15
326 Health Seeking Behavior After The 2013-16 Ebola Epidemic: Lassa Fever As A Metric of Persistent Changes in Kenema District, Sierra Leone
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Abstract: The West African Ebola epidemic of 2013-2016 killed nearly 4,000 Sierra Leoneans and devastated health infrastructure across West Africa. Changes in health seeking behavior (HSB) …		 MIKAELA R KOCH et. al. PLoS neglected tropical diseases 2021-07-14
327 Ebola As A Case Study for The Patent Landscape of Medical Countermeasures for Emerging Infectious Diseases
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 Nasir Mohajel; Arash Arashkia; Nature biotechnology 2021-07-14
328 Motivators of Continued Participation in Public Health Emergency Response Among Federal Public Health Workers: A Qualitative Study
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Abstract: The purpose of this study was to identify factors that motivate public health workers to deploy to the field during an emergency event. We conducted 25 semistructured interviews …		 Shawn C Chiang; Holly H Fisher; Matthew E Bridwell; Bobby B Rasulnia; Sachiko A Kuwabara; Health security 2021-07-13
329 Structural Insight Into Marburg Virus Nucleoprotein-RNA Complex Formation
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Highlight: Here, we show the structure of the MARV NP-RNA complex determined using cryo-electron microscopy at a resolution of 3.1 angstrom.		 Y. FUJITA-FUJIHARU et. al. bio.microbiology 2021-07-13
330 Factors Associated with Length of Stay and Treatment Outcome of Ebola Patients Treated at An Ebola Treatment Center in Sierra Leone During The Peak Period of The West African Ebola Outbreak 2013-2016
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Abstract: The World Health Organization (WHO) declared the West Africa Ebola epidemic as a Public Health Emergency of International Concern in August 2014. During the outbreak period, there …		 Jia Bainga Kangbai; Christian Heumann; Michael Hoelscher; Foday Sahr; Guenter Froeschl; Archives of public health = Archives belges de sante … 2021-07-12
331 Development and Evaluation of An Ebola Virus Glycoprotein Mucin-Like Domain Replacement System As A New Dendritic Cell-Targeting Vaccine Approach Against HIV-1
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Abstract: The development of efficient vaccine approaches against HIV infection remains challenging in the vaccine field. Here, we developed an Ebola virus envelope glycoprotein …		 ZHUJUN AO et. al. Journal of virology 2021-07-12
332 Therapeutic Antibodies Under Development for SARS-CoV-2
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Abstract: The world is experiencing one of the most difficult moments in history with COVID-19, which has rapidly developed into a worldwide pandemic with a significant health and economic …		 ZETONG MA et. al. View (Beijing, China) 2021-07-12
333 Why Remdesivir Failed: Preclinical Assumptions Overestimate The Clinical Efficacy of Remdesivir for COVID-19 and Ebola
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Abstract: Remdesivir is a nucleoside monophosphoramidate prodrug that has been FDA approved for coronavirus disease 2019 (COVID-19). However, the clinical efficacy of remdesivir for …		 Victoria C Yan; Florian L Muller; Antimicrobial agents and chemotherapy 2021-07-12
334 Religion, Social Connectedness, and Xenophobic Responses to Ebola
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Abstract: This study examined the role of religion in xenophobic responses to the threat of Ebola. Religious communities often offer members strong social ties and social support, which may …		 Roxie Chuang; Kimin Eom; Heejung S Kim; Frontiers in psychology 2021-07-12
335 A Call to Safeguard Sexual and Reproductive Health Information and Services During Ebola Outbreaks
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Abstract: The recent Ebola virus disease (EVD) outbreaks in 2021 exemplify how sexual and reproductive health services are too often considered unessential during health emergencies. …		 Nguyen Toan Tran; Désirée Lichtenstein; Benjamin Black; Alice Rosmini; Catrin Schulte-Hillen; Conflict and health 2021-07-10
336 Knowledge, Perceptions and Effects of Ebola Virus Disease Outbreak on The Pig Value Chain in The Agro-pastoralist District of Luwero, Central Uganda
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Abstract: Ebola Virus Disease (EVD) outbreaks have a significant impact on the health and wellbeing, and livelihoods of communities. EVD response interventions particularly affect the food …		 DOREEN BIRUNGI et. al. BMC infectious diseases 2021-07-09
337 Implementation of The Ebola Virus Persistence in Ocular Tissues and Fluids (EVICT) Study: Lessons Learned for Vision Health Systems Strengthening in Sierra Leone
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Abstract: Following the West African Ebola virus disease (EVD) outbreak of 2013-2016 and more recent EVD outbreaks in the Democratic Republic of Congo, thousands of EVD survivors are …		 JESSICA G SHANTHA et. al. PloS one 2021-07-09
338 What Factors Promote Vaccine Hesitancy or Acceptance During Pandemics? A Systematic Review and Thematic Analysis
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Abstract: Examine the factors that promote vaccine hesitancy or acceptance during pandemics, major epidemics and global outbreaks. A systematic review and thematic analysis of 28 studies on …		 Judy Truong; Simran Bakshi; Aghna Wasim; Mobeen Ahmad; Umair Majid; Health promotion international 2021-07-09
339 The East African Community (EAC) Mobile Laboratory Networks in Kenya, Burundi, Tanzania, Rwanda, Uganda, and South Sudan-from Project Implementation to Outbreak Response Against Dengue, Ebola, COVID-19, and Epidemic-prone Diseases
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Abstract: East Africa is home to 170 million people and prone to frequent outbreaks of viral haemorrhagic fevers and various bacterial diseases. A major challenge is that epidemics mostly …		 MUNA AFFARA et. al. BMC medicine 2021-07-09
340 ‘I Can’t Leave Everything in The Hands of My Husband’: Economic Constraints and Gender Roles in Care-seeking in Post-Ebola Guinea
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Abstract: The 2014-2016 Ebola epidemic in West Africa had enduring effects on health systems and healthcare utilisation. This study explores the intersection of economic constraints and …		 ZOÉ MISTRALE HENDRICKSON et. al. Global public health 2021-07-09
341 From Ebola to COVID-19: Emergency Preparedness and Response Plans and Actions in Lagos, Nigeria
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Abstract: Lagos state is the industrial nerve centre of Nigeria and was the epicentre of the 2014 Ebola outbreak in Nigeria as it is now for the current Coronavirus Disease (COVID-19) …		 AKIN ABAYOMI et. al. Globalization and health 2021-07-09
342 ADME and Pharmacokinetic Properties of Remdesivir: Its Drug Interaction Potential
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Abstract: On 11 March 2020, the World Health Organization (WHO) classified the Coronavirus Disease 2019 (COVID-19) as a global pandemic, which tested healthcare systems, administrations, …		 Subrata Deb; Anthony Allen Reeves; Robert Hopefl; Rebecca Bejusca; Pharmaceuticals (Basel, Switzerland) 2021-07-08
343 PTSD, Depression and Anxiety in Ebola Virus Disease Survivors in Beni Town, Democratic Republic of The Congo
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Abstract: Ebola Virus Disease (EVD) is a deadly and feared infectious disease, which can be responsible of debilitating physical and psychological sequelae in survivors including depression …		 Célestin Kaputu-Kalala-Malu; Eric Mafuta Musalu; Tim Walker; Olga Ntumba-Tshitenge; Steve Ahuka-Mundeke; BMC psychiatry 2021-07-08
344 The Impact of Case and Contact Characteristics on Contact Tracing During The West Africa Ebola Epidemic
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 Jessica L Longley; Lisa O Danquah; M Sofia Massa; David A Ross; Helen A Weiss; The Journal of infection 2021-07-08
345 Seroprevalence and Associated Risk Factors of Selected Zoonotic Viral Hemorrhagic Fevers in Tanzania
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Abstract: To determine the seroprevalence of selected zoonotic viral hemorrhagic fevers (VHFs) and their associated risk factors in Tanzania. Blood samples were collected from consenting …		 SIMA RUGARABAMU et. al. International journal of infectious diseases : IJID : … 2021-07-07
346 Psychosocial Effects of Isolation on Nipah Virus Infection Suspects During An Outbreak
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Abstract: Nipah Virus (NiV) belonging to the genus Henipavirus is a biosafety level 4 pathogen with high human to human transmission. Nipah Virus outbreak of 2018 in Kozhikode, Kerala has …		 Shyam Mohan Kannampulakkal; Swathy Sheela Sudevan; Harish M Tharayil; Chandni Radhakrishnan; The Journal of the Association of Physicians of India 2021-07-06
347 A Hybrid Simulation Model to Study The Impact of Combined Interventions on Ebola Epidemic
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Abstract: Pandemics have been recognized as a serious global threat to humanity. To effectively prevent the spread and outbreak of the epidemic disease, theoretical models intended to …		 Peiyu Chen; Wenhui Fan; Xudong Guo; PloS one 2021-07-06
348 (Re)arranging systems of Care in The Early Ebola Response in Sierra Leone: An Interdisciplinary Analysis
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Abstract: Despite an expanding literature on Ebola-response, few studies detail or reflect on the responses of diverse systems of care. Little is known about how, why or in what ways, …		 SUSANNAH H MAYHEW et. al. Social science & medicine (1982) 2021-07-06
349 Expression of The Ebola Virus VP24 Protein Compromises The Integrity of The Nuclear Envelope and Induces A Laminopathy-Like Cellular Phenotype
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Abstract: Ebola virus (EBOV) VP24 protein is a nucleocapsid-associated protein that inhibits interferon (IFN) gene expression and counteracts the IFN-mediated antiviral response, preventing …		 SANTIAGO VIDAL et. al. mBio 2021-07-06
350 Exclusivity of Cultural Practices Within Emerging Disease Outbreak Responses in Developing Nations Leads to Detrimental Outcomes
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Abstract: A number of organizations provide aid and medical care to areas affected by emerging infectious disease outbreaks. This process oftentimes involves organizations traveling to …		 Arnav Lal; Frontiers in public health 2021-07-06
351 The Relationship Between Anxiety and Hopelessness Levels Among Nursing Students During The COVID-19 Pandemic and Related Factors
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Abstract: Outbreaks caused by environmental effects such as COVID-19, MERS, SARS, or Ebola cause problems such as fear, anxiety, loneliness, depression, and hopelessness for people with or …		 Emine Kaplan Serin; Runida Doğan; Omega 2021-07-04
352 The Impact of Past Pandemics on Economic and Gender Inequalities
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Abstract: This paper estimates how previous major pandemic events affected economic and gender inequalities in the short- to medium run. We consider the impact of six major pandemic …		 Michal Brzezinski; Economics and human biology 2021-07-03
353 Natural History of Disease in Cynomolgus Monkeys Exposed to Ebola Virus Kikwit Strain Demonstrates The Reliability of This Non-human Primate Model for Ebola Virus Disease
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Abstract: Filoviruses (Family Filoviridae genera Ebolavirus and Marburgvirus) are negative-stranded RNA viruses that cause severe health effects in humans and non-human primates, including …		 NANCY A NIEMUTH et. al. PloS one 2021-07-02
354 What Do The Aftermath of The 2010 Haiti Earthquake, Hurricane Sandy, The Boston Marathon Bombing, The 2013 Ebola Outbreak, and The COVID-19 Pandemic Have in Common?
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 Antonia Kolokythas; Oral surgery, oral medicine, oral pathology and oral … 2021-07-02
355 Structural Plasticity of Mumps Virus Nucleocapsids with Cryo-EM Structures
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Abstract: Mumps virus (MuV) is a highly contagious human pathogen and frequently causes worldwide outbreaks despite available vaccines. Similar to other mononegaviruses such as Ebola and …		 HONG SHAN et. al. Communications biology 2021-07-02
356 Hyperimmune Plasma in Three Immuno-deficient Patients Affected By Non-severe, Prolonged COVID-19: A Single-center Experience
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Abstract: Convalescent plasma (CP) and hyperimmune plasma (HP) are passive immunotherapies consisting in the infusion of plasma from recovered people into infected patients. Following …		 MARIA GRAZIA CUSI et. al. BMC infectious diseases 2021-07-01
357 Macro Level Factors Influencing Strategic Responses to Emergent Pandemics: A Scoping Review
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Abstract: Strategic planning is critical for successful pandemic management. This study aimed to identify and review the scope and analytic depth of situation analyses conducted to …		 NINA J ZHU et. al. Journal of global health 2021-07-01
358 New Mixed Methods Approach for Monitoring Community Perceptions of Ebola and Response Efforts in The Democratic Republic of The Congo
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Abstract: Efforts to contain the spread of Ebola in the eastern Democratic Republic of the Congo (DRC) during the 2018-2020 epidemic faced challenges in gaining community trust and …		 GIULIA EARLE-RICHARDSON et. al. Global health, science and practice 2021-06-30
359 [Preparation, Trust and Uncertainty in The Time of An Ebola Crisis]
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Abstract: The notions of risk and crisis, which shape the management of epidemics, were studied from a social sciences perspective. An angle which provides further reflection on how teams …		 Clément Tarantini; Soins; la revue de reference infirmiere 2021-06-30
360 Influenza Vaccination Coverage and Intention to Receive Hypothetical Ebola and COVID-19 Vaccines Among Medical Students
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Abstract: The study aimed to determine influenza vaccine uptake among medical students and their intention to receive a hypothetical Ebola or COVID-19 vaccine. This cross-sectional …		 Ewa Talarek; Joanna Warzecha; Marcin Banasiuk; Aleksandra Banaszkiewicz; Vaccines 2021-06-30
361 Real-Time Tracking of COVID-19 Rumors Using Community-Based Methods in Côte D’Ivoire
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Abstract: Global misinformation and information overload have characterized the coronavirus disease (COVID-19) pandemic. Rumors are unverified pieces of information spreading online or …		 NATALIE TIBBELS et. al. Global health, science and practice 2021-06-30
362 Challenges in Maternal and Child Health Services Delivery and Access During Pandemics or Public Health Disasters in Low-and Middle-Income Countries: A Systematic Review
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Abstract: Maternal and child health (MCH) has been a global priority for many decades and is an essential public health service. Ensuring seamless delivery is vital for desirable MCH …		 KRUSHNA CHANDRA SAHOO et. al. Healthcare (Basel, Switzerland) 2021-06-30
363 Evaluating The Effects of News-following, Volume and Content of News Coverage on Americans’ Risk Perceptions During The 2014-2016 Ebola Outbreak
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Abstract: We used the 2014-2016 Ebola outbreak to examine the relationships between risk perceptions and media coverage (volume and content). We analyzed how public opinion from …		 Christopher D Wirz; Marcus Mayorga; Branden B Johnson; Journal of health communication 2021-06-29
364 A Review and Agenda for Integrated Disease Models Including Social and Behavioural Factors
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Abstract: Social and behavioural factors are critical to the emergence, spread and containment of human disease, and are key determinants of the course, duration and outcomes of disease …		 JAMIE BEDSON et. al. Nature human behaviour 2021-06-28
365 Air Quality Monitoring During High-Level Biocontainment Ground Transport: Observations From Two Operational Exercises
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Abstract: Stretcher transport isolators provide mobile, high-level biocontainment outside the hospital for patients with highly infectious diseases, such as Ebola virus disease. Air quality …		 AUDREY DANG et. al. Disaster medicine and public health preparedness 2021-06-28
366 Equitable and Feasible Distribution of SARS-CoV-2 Vaccines for All in Africa
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Abstract: As the fight against the coronavirus disease 2019 (COVID-19) pandemic continues, the necessity for wide-scale, global vaccine rollout to reduce the spread of severe acute …		 Abu Bakarr Rogers; Mohamed Bailor Barrie; Mosoka P Fallah; J Daniel Kelly; The American journal of tropical medicine and hygiene 2021-06-28
367 Trends in The Development of Remdesivir Based Inventions Against COVID-19 and Other Disorders: A Patent Review
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Abstract: The development of remdesivir has been a breakthrough for COVID-19 treatment. It has been approved in about 50 countries, including Saudi Arabia, since 2020. The generic structure …		 Mohd Imran; Ahmed Subeh Alshrari; Syed Mohammed Basheeruddin Asdaq; SMB Abida; Journal of infection and public health 2021-06-27
368 Glyconanomaterials for Human Virus Detection and Inhibition
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Abstract: Viruses are among the most infectious pathogens, responsible for the highest death toll around the world. Lack of effective clinical drugs for most viral diseases emphasizes the …		 Noelia Losada-Garcia; Carla Garcia-Sanz; Alicia Andreu; Trinidad Velasco-Torrijos; Jose M Palomo; Nanomaterials (Basel, Switzerland) 2021-06-26
369 Defibrotide: Potential for Treating Endothelial Dysfunction Related to Viral and Post-infectious Syndromes
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Abstract: Defibrotide (DF) is a polyribonucleotide with antithrombotic, pro-fibrinolytic, and anti-inflammatory effects on endothelium. These effects and the established safety of DF …		 EDWARD RICHARDSON et. al. Expert opinion on therapeutic targets 2021-06-25
370 Flavonoids As Promising Antiviral Agents Against SARS-CoV-2 Infection: A Mechanistic Review
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Abstract: A newly diagnosed coronavirus in 2019 (COVID-19) has affected all human activities since its discovery. Flavonoids commonly found in the human diet have attracted a lot of …		 Mohammad Amin Khazeei Tabari; Amin Iranpanah; Roodabeh Bahramsoltani; Roja Rahimi; Molecules (Basel, Switzerland) 2021-06-25
371 Ebola Virus Disease, Stigmatization, Peritraumatic Distress, and Posttraumatic Stress Disorder in The Democratic Republic of The Congo: A Moderated Mediation Model
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Abstract: Mechanisms worsening the development of Posttraumatic stress disorder (PTSD) symptoms among individuals affected by high-mortality epidemics are unclear. This study examined the …		 JUDE MARY CÉNAT et. al. Journal of affective disorders 2021-06-25
372 How to Improve Outbreak Response: A Case Study of Integrated Outbreak Analytics from Ebola in Eastern Democratic Republic of The Congo
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Abstract: The emerging field of outbreak analytics calls attention to the need for data from multiple sources to inform evidence-based decision making in managing infectious diseases …		 SIMONE E CARTER et. al. BMJ global health 2021-06-25
373 Risk Perceptions and Preventive Practices of COVID-19 Among Healthcare Professionals in Public Hospitals in Addis Ababa, Ethiopia
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Abstract: Healthcare professionals are at higher risk of contracting the new coronavirus disease 2019 (COVID-19). Although appropriate preventive measures are the most important …		 Wakgari Deressa; Alemayehu Worku; Workeabeba Abebe; Muluken Gizaw; Wondwossen Amogne; PloS one 2021-06-25
374 Explainable Deep Neural Networks for Novel Viral Genome Prediction
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Abstract: Viral infection causes a wide variety of human diseases including cancer and COVID-19. Viruses invade host cells and associate with host molecules, potentially disrupting the …		 Chandra Mohan Dasari; Raju Bhukya; Applied intelligence (Dordrecht, Netherlands) 2021-06-25
375 The 2021 Ebola Virus Outbreak in Guinea: Mistrust and The Shortcomings of Outbreak Surveillance
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 Manuel Raab; Emmanuelle Roth; Vinh-Kim Nguyen; Guenter Froeschl; PLoS neglected tropical diseases 2021-06-24
376 Antagonism of STAT3 Signalling By Ebola Virus
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Abstract: Many viruses target signal transducers and activators of transcription (STAT) 1 and 2 to antagonise antiviral interferon signalling, but targeting of signalling by other …		 ANGELA R HARRISON et. al. PLoS pathogens 2021-06-24
377 Correlation-Based Analysis of COVID-19 Virus Genome Versus Other Fatal Virus Genomes
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Abstract: Virus attacks have had devastating effects on mankind. The prominent viruses such as Ebola virus (2012), SARS-CoV or Severe acute respiratory syndrome, Middle East respiratory …		 Sidharth Purohit; Suresh Chandra Satapathy; S Sibi Chakkaravarthy; Yu-Dong Zhang; Arabian journal for science and engineering 2021-06-24
378 Antibody Responses to Filovirus Infections in Humans: Protective or Not?
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Abstract: Disease outbreaks caused by Ebola virus and other filoviruses highlight the urgent need for an in-depth understanding of the role of antibody responses in recovery. In this …		 Philipp A Ilinykh; Alexander Bukreyev; The Lancet. Infectious diseases 2021-06-24
379 [Why Does The Ebola Virus Epidemic Continue to Plague The Democratic Republic of The Congo?]
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Abstract: Why does the ebola virus epidemic continue to plague the democratic republic Of the congo?Ebola virus disease outbreak continues in North Kivu and Ituri provinces in the …		 Christophe Vanhecke; Junior Muwalawala; Mbambu Mahamba Mbambu Mahamba; Rémi Girerd; Bernard-Alex Gaüzère; La Revue du praticien 2021-06-23
380 Drug Repurposing for COVID-19: Approaches, Challenges and Promising Candidates
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Abstract: Traditional drug development and discovery has not kept pace with threats from emerging and re-emerging diseases such as Ebola virus, MERS-CoV and more recently, SARS-CoV-2. Among …		 Yan Ling Ng; Cyrill Kafi Salim; Justin Jang Hann Chu; Pharmacology & therapeutics 2021-06-23
381 Long COVID or Post-acute Sequelae of COVID-19 (PASC): An Overview of Biological Factors That May Contribute to Persistent Symptoms
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Abstract: The novel virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a pandemic of coronavirus disease 2019 (COVID-19). Across the globe, a subset of patients …		 Amy D Proal; Michael B VanElzakker; Frontiers in microbiology 2021-06-23
382 The Impact of Epidemics and Pandemics on The Mental Health of Healthcare Workers: A Systematic Review
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Abstract: There is increasing evidence that healthcare workers (HCWs) experience significant psychological distress during an epidemic or pandemic. Considering the increase in emerging …		 Ottilia Cassandra Chigwedere; Anvar Sadath; Zubair Kabir; Ella Arensman; International journal of environmental research and public … 2021-06-22
383 Broad Impact of Exchange Protein Directly Activated By CAMP 2 (EPAC2) on Respiratory Viral Infections
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Abstract: The recently discovered exchange protein directly activated by cAMP (EPAC), compared with protein kinase A (PKA), is a fairly new family of cAMP effectors. Soon after the …		 EUN-JIN CHOI et. al. Viruses 2021-06-21
384 The Application of A Safe Neutralization Assay for Ebola Virus Using Lentivirus-Based Pseudotyped Virus
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 ZENGGUO CAO et. al. Virologica Sinica 2021-06-21
385 Potential Pharmacological Strategies Targeting The Niemann-Pick C1 Receptor and Ebola Virus Glycoprotein Interaction
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Abstract: Niemann-Pick C1 (NPC1) receptor is an intracellular protein located in late endosomes and lysosomes whose main function is to regulate intracellular cholesterol trafficking. …		 MARCOS MORALES-TENORIO et. al. European journal of medicinal chemistry 2021-06-19
386 Drawing Parallels Among Past Public Health Crises and COVID-19
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Abstract: In the early stages of the coronavirus disease 2019 (COVID-19) pandemic, there were shortages of personal protective equipment (PPE) and health-care personnel across severely …		 GEORGE W CONTRERAS et. al. Disaster medicine and public health preparedness 2021-06-18
387 Illegal Wildlife Trade and Emerging Infectious Diseases: Pervasive Impacts to Species, Ecosystems and Human Health
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Abstract: Emerging infectious disease (EID) events can be traced to anthropogenic factors, including the movement of wildlife through legal and illegal trade. This paper focuses on the link …		 Elizabeth R Rush; Erin Dale; A Alonso Aguirre; Animals : an open access journal from MDPI 2021-06-18
388 SARS-CoV-2 Variants and The So-called Resistance to Vaccines
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Abstract: RNA viruses (except retroviruses) replicate by the action of an RNA-dependent RNA polymerase, which lacks a proofreading exonuclease and, consequently, errors may occur in each …		 Isabel N Kantor; Isabel A Lüthy; Viviana Ritacco; Medicina 2021-06-17
389 Luminore CopperTouch Surface Coating Effectively Inactivates SARS-CoV-2, Ebola Virus, and Marburg Virus In Vitro
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Abstract: We investigated the ability of Luminore CopperTouch copper and copper-nickel surfaces to inactivate filoviruses and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). …		 Emily K Mantlo; Slobodan Paessler; Alexey Seregin; Alfred Mitchell; Antimicrobial agents and chemotherapy 2021-06-17
390 Reported Health and Social Consequences of The COVID-19 Pandemic on Vulnerable Populations and Implemented Solutions in Six West African Countries: A Media Content Analysis
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Abstract: Coronavirus has spread worldwide with over 140 million cases and resulting in more than 3 million deaths between November 2019 to April 2021, threatening the socio-economic and …		 KHALIDA SAALIM et. al. PloS one 2021-06-16
391 High Levels of Antibiotic Resistance Patterns in Two Referral Hospitals During The Post-Ebola Era in Free-Town, Sierra Leone: 2017-2019
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Abstract: The Post-Ebola era (2017-2019) presented an opportunity for laboratory investments in Sierra Leone. US CDC supported the Ministry of Health and Sanitation to establish a …		 ZIKAN KOROMA et. al. Tropical medicine and infectious disease 2021-06-16
392 Scoping Future Outbreaks: A Scoping Review on The Outbreak Prediction of The WHO Blueprint List of Priority Diseases
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Abstract: The WHO’s Research and Development Blueprint priority list designates emerging diseases with the potential to generate public health emergencies for which insufficient preventive …		 Nils Jonkmans; Valérie D’Acremont; Antoine Flahault; BMJ global health 2021-06-15
393 Protective Population Behavior Change in Outbreaks of Emerging Infectious Disease
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Abstract: During outbreaks of emerging and re-emerging infections, the lack of effective drugs and vaccines increases reliance on non-pharmacologic public health interventions and behavior …		 Evans K Lodge; Annakate M Schatz; John M Drake; BMC infectious diseases 2021-06-15
394 Cyanovirin-N Binds Viral Envelope Proteins at The Low-Affinity Carbohydrate Binding Site Without Direct Virus Neutralization Ability
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Abstract: Glycan-targeting antibodies and pseudo-antibodies have been extensively studied for their stoichiometry, avidity, and their interactions with the rapidly modifying glycan shield …		 Irene Maier; Robert H Schiestl; Georg Kontaxis; Molecules (Basel, Switzerland) 2021-06-13
395 Remdesivir Inhibits The Polymerases of The Novel Filoviruses Lloviu and Bombali Virus
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Abstract: In recent years, a number of novel filoviruses (e.g. Lloviu virus (LLOV) and Bombali virus (BOMV)) have been discovered. While antibody-based therapeutics have recently been …		 BIANCA S BODMER et. al. Antiviral research 2021-06-12
396 Distinct Transcriptional Responses to Fatal Ebola Virus Infection in Cynomolgus and Rhesus Macaques Suggest Species-specific Immune Responses
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Abstract: Ebola virus (EBOV) is a negative single-stranded RNA virus within the family and the causative agent of Ebola virus disease (EVD). Nonhuman primates (NHPs), including cynomolgus …		 Amanda N Pinski; Kevin J Maroney; Andrea Marzi; Ilhem Messaoudi; Emerging microbes & infections 2021-06-11
397 Infectious Agents Including COVID-19 and The Involvement of Blood Coagulation and Fibrinolysis. A Narrative Review
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Abstract: Platelets, blood coagulation along with fibrinolysis are greatly involved in the pathophysiology of infectious diseases induced by bacteria, parasites and virus. This phenomenon …		 F MARONGIU et. al. European review for medical and pharmacological sciences 2021-06-10
398 Mechanism of Inhibition of The Reproduction of SARS-CoV-2 and Ebola Viruses By Remdesivir
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Abstract: Remdesivir is an antiviral drug initially designed against the virus. The results obtained with it both in biochemical studies and in cell line assays were very promising, but it …		 JIMIN WANG et. al. Biochemistry 2021-06-10
399 Emerging and Re-emerging Infections in Children: COVID/ MIS-C, Zika, Ebola, Measles, Varicella, Pertussis … Immunizations
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Abstract: The role of the emergency provider lies at the forefront of recognition and treatment of novel and re-emerging infectious diseases in children. Familiarity with disease …		 Carol C Chen; Anne Whitehead; Emergency medicine clinics of North America 2021-06-10
400 Comparative Analysis of Viral Infection Outcomes in Human Seminal Fluid from Prior Viral Epidemics and Sars-CoV-2 May Offer Trends for Viral Sexual Transmissibility and Long-term Reproductive Health Implications
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Abstract: Viral detection in seminal fluid indicates their potential for both sexual transmission and impairment of reproductive health. Review of the mechanistic entry, sexual transmission …		 JAMES FREDERICK W PIKE et. al. Reproductive health 2021-06-10
401 P300-mediated NEDD4 Acetylation Drives Ebolavirus VP40 Egress By Enhancing NEDD4 Ligase Activity
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Abstract: The final stage of Ebola virus (EBOV) replication is budding from host cells, where the matrix protein VP40 is essential for driving this process. Many post-translational …		 LINLIANG ZHANG et. al. PLoS pathogens 2021-06-10
402 Ebola Virus Glycoprotein Domains Associated with Protective Efficacy
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Abstract: Ebola virus (EBOV) is the cause of sporadic outbreaks of human hemorrhagic disease in Africa, and the best-characterized virus in the filovirus family. The West African epidemic …		 Bharti Bhatia; Wakako Furuyama; Thomas Hoenen; Heinz Feldmann; Andrea Marzi; Vaccines 2021-06-10
403 Clinical Laboratory Biosafety Gaps: Lessons Learned from Past Outbreaks Reveal A Path to A Safer Future
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Abstract: Patient care and public health require timely, reliable laboratory testing. However, clinical laboratory professionals rarely know whether patient specimens contain infectious …		 NANCY E CORNISH et. al. Clinical microbiology reviews 2021-06-09
404 Transfer Learning for Predicting Virus-Host Protein Interactions for Novel Virus Sequences
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Highlight: We propose DeepVHPPI, a novel deep learning framework combining a self-attention-based transformer architecture and a transfer learning training strategy to predict interactions between human proteins and virus proteins that have novel sequence patterns.		 J. Lanchantin; T. Weingarten; A. Sekhon; C. L. Miller; Y. Qi; bio.bioinformatics 2021-06-08
405 Delays in Reporting and Publishing Trial Results During Pandemics: Cross Sectional Analysis of 2009 H1N1, 2014 Ebola, and 2016 Zika Clinical Trials
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Abstract: Pandemic events often trigger a surge of clinical trial activity aimed at rapidly evaluating therapeutic or preventative interventions. Ensuring rapid public access to the …		 CHRISTOPHER W JONES et. al. BMC medical research methodology 2021-06-08
406 The Ebola Virus Matrix Protein Clusters Phosphatidylserine, A Critical Step in Viral Budding
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Highlight: Here, we describe the ability of the Ebola virus (EBOV) matrix protein eVP40 to induce clustering of PS and promote viral budding in vitro, as well as the ability of an FDA approved drug, fendiline, to reduce PS clustering subsequently reducing virus budding and entry.		 M. L. HUSBY et. al. bio.microbiology 2021-06-08
407 Role of Systems Science in Preventing and Controlling Emerging Infectious Diseases: Protocol for A Scoping Review
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Abstract: In recent history, many new infectious diseases have affected humans for the first time or have appeared in previously unaffected areas of the world; these diseases are known as …		 Mariam Abdulmonem Mansouri; Frank Kee; Leandro Garcia; Declan T Bradley; BMJ open 2021-06-08
408 Signal-regulatory Protein Alpha Is An Anti-viral Entry Factor Targeting Viruses Using Endocytic Pathways
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Abstract: Signal-regulatory protein alpha (SIRPA) is a well-known inhibitor of phagocytosis when it complexes with CD47 expressed on target cells. Here we show that SIRPA decreased in vitro …		 NICOLÁS SARUTE et. al. PLoS pathogens 2021-06-07
409 Estimating Time-Dependent Disease Transmission Intensity Using Reported Data: An Application to Ebola and Selected Public Health Problems
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Highlight: Obtaining reasonable estimates for transmission rates from observed data is a challenge when using mathematical models to study the dynamics of infectious diseases, like Ebola.		 A. GHOSH et. al. med.epidemiology 2021-06-07
410 Efficacy and Safety of Dihydroorotate Dehydrogenase (DHODH) Inhibitors leflunomide and teriflunomide in Covid-19: A Narrative Review
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Abstract: Dihydroorotate dehydrogenase (DHODH) is rate-limiting enzyme in biosynthesis of pyrimidone which catalyzes the oxidation of dihydro-orotate to orotate. Orotate is utilized in the …		 HARDEEP KAUR et. al. European journal of pharmacology 2021-06-07
411 Hot Water Extract of Arthrospira Maxima (AHWE) Has Broad-spectrum Antiviral Activity Against RNA Virus Including Coronavirus SARS-CoV2, and The Antivirus Spray Application
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Highlight: In conclusion, this study suggests that AHWE could be developed as a potential broad-spectrum antivirus spray product and therapeutic agent.		 Y.-H. Chen; Y.-C. Liao; J. Y. Huang; Y.-A. Kung; C.-C. Chiueh; bio.microbiology 2021-06-07
412 Hidden Tales of Ebola: Airing The Forgotten Voices of Ugandan Ebola Nurses
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Abstract: According to the Centers for Disease Control and Prevention, Ebola has affected the lives of thousands, including health care workers. With few studies describing the experience …		 ISAAC OKELLO WONYIMA et. al. Journal of transcultural nursing : official journal of the … 2021-06-06
413 Sustainable Laboratory Capacity Building After The 2014 Ebola Outbreak in The Republic of Guinea
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Abstract: The 2014-2016 West Africa Ebola virus disease outbreak heavily impacted the Republics of Guinea, Sierra Leone, and Liberia. The outbreak uncovered the weaknesses of the public …		 JEAN NDJOMOU et. al. Frontiers in public health 2021-06-04
414 Differential Laboratory Diagnosis of Acute Fever in Guinea: Preparedness for The Threat of Hemorrhagic Fevers
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Abstract: Acute febrile illnesses occur frequently in Guinea. Acute fever itself is not a unique, hallmark indication (pathognomonic sign) of any one illness or disease. In the infectious …		 VLADIMIR G DEDKOV et. al. International journal of environmental research and public … 2021-06-03
415 The Healthcare Sector Employer’s Duty of Care: Implications for Worker Well-Being
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Abstract: Pandemic diseases of this century have differentially targeted healthcare workers globally. These infections include Severe Acute Respiratory Syndrome SARS, the Middle East …		 Melissa McDiarmid; Marian Condon; Joanna Gaitens; International journal of environmental research and public … 2021-06-03
416 Knowledge of Infection Prevention and Control Among Healthcare Workers and Factors Influencing Compliance: A Systematic Review
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Abstract: Knowledge of infection prevention and control (IPC) procedures among healthcare workers (HCWs) is crucial for effective IPC. Compliance with IPC measures has critical implications …		 SAAD ALHUMAID et. al. Antimicrobial resistance and infection control 2021-06-03
417 Leapfrogging with Technology: Introduction of A Monitoring Platform to Support A Large-scale Ebola Vaccination Program in Rwanda
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Abstract: Continued outbreaks of Ebola virus disease, including recent outbreaks in the Democratic Republic of the Congo (DRC), highlight the need for effective vaccine programs to combat …		 PAULA MC KENNA et. al. Human vaccines & immunotherapeutics 2021-06-02
418 Low-Cost Optical Assays for Point-of-Care Diagnosis in Resource-Limited Settings
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Abstract: Readily deployable, low-cost point-of-care medical devices such as lateral flow assays (LFAs), microfluidic paper-based analytical devices (μPADs), and microfluidic thread-based …		 NAN JIANG et. al. ACS sensors 2021-06-02
419 Correction To: Under Consent: Participation of People with HIV in An Ebola Vaccine Trial in Canada
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 Pierre-Marie David; Benjamin Mathiot; Oumy Thiongane; Janice E Graham; BMC medical ethics 2021-06-01
420 The Genetic Impact of An Ebola Outbreak on A Wild Gorilla Population
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Highlight: Conclusion: This study offers the first insight to the genetics of a wild great ape population before and after an Ebola outbreak using target capture experiments from fecal samples, and presents a list of candidate loci that may have facilitated their survival.		 C. FONTSERE et. al. bio.genomics 2021-05-31
421 Impact of Recurrent Outbreaks of Ebola Virus Disease in Africa: A Meta-analysis of Case Fatality Rates
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Abstract: Between 2010 and 2020, Africa witnessed several outbreaks of Ebola virus disease (EVD), each presenting with varying case fatality rate (CFR) and other socio-economic impacts. …		 J Kawuki; T H Musa; X Yu; Public health 2021-05-30
422 Training and Education of Healthcare Workers During Viral Epidemics: A Systematic Review
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Abstract: It is necessary to train a large number of healthcare workers (HCW) within a limited time to ensure adequate human resources during an epidemic. There remains an urgent need for …		 Leizl Joy Nayahangan; Lars Konge; Lene Russell; Steven Andersen; BMJ open 2021-05-28
423 Finding The Graves: SLED Family Reunification Program
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Abstract: In 2015, the Sierra Leone Ministry of Health and Sanitation (MoHS) and the Centers for Disease Control and Prevention (CDC) agreed to consolidate data recorded by MoHS and …		 DIANA BENSYL et. al. Annals of epidemiology 2021-05-28
424 Monitoring Symptoms of Infectious Diseases: Perspectives for Printed Wearable Sensors
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Abstract: Infectious diseases possess a serious threat to the world’s population, economies, and healthcare systems. In this review, we cover the infectious diseases that are most likely to …		 Ala’aldeen Al-Halhouli; Ahmed Albagdady; Ja’far Alawadi; Mahmoud Abu Abeeleh; Micromachines 2021-05-27
425 Sierra Leone: Ebola and War Survivors Failed By Lack of Mental Health Services, Amnesty Finds
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 Elisabeth Mahase; BMJ (Clinical research ed.) 2021-05-27
426 Gaps in Infection Prevention and Control in Public Health Facilities of Sierra Leone After The 2014-2015 Ebola Outbreak
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Abstract: High compliance to infection prevention and control (IPC) is vital to prevent health care-associated infections. In the worst 2014-2015 Ebola-affected district in Sierra Leone …		 JAMES SYLVESTER SQUIRE et. al. Tropical medicine and infectious disease 2021-05-26
427 Anti-viral Treatment for SARS-CoV-2 Infection: A Race Against Time Amidst The Ongoing Pandemic
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Abstract: Remdesivir (GS-5734), a drug initially developed to treat hepatitis C and Ebola virus disease, was the first approved treatment for severe coronavirus disease 2019 (COVID-19). …		 Natalia G Vallianou; Dimitrios Tsilingiris; Gerasimos Socrates Christodoulatos; Irene Karampela; Maria Dalamaga; Metabolism open 2021-05-25
428 Ebola, Dengue, Chikungunya, and Zika Infections in Neonates and Infants
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Abstract: Emerging infectious diseases, including Ebola, chikungunya, Zika, and dengue, may have significant impacts on maternal-fetal dyads and neonatal outcomes. Pregnant women infected …		 Annabelle de St Maurice; Elizabeth Ervin; Alison Chu; Clinics in perinatology 2021-05-25
429 Effective High-throughput Isolation of Fully Human Antibodies Targeting Infectious Pathogens
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Abstract: As exemplified by the ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, there is a strong demand for rapid high-throughput isolation pipelines to …		 LUTZ GIESELMANN et. al. Nature protocols 2021-05-25
430 Development and Validation of Portable, Field-deployable Ebola Virus Point-of-encounter Diagnostic Assay for Wildlife Surveillance
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Abstract: Early detection of Ebola virus spillover into wildlife is crucial for rapid response. We developed and validated a portable, cold-chain independent Ebola virus RT-qPCR assay. The …		 DANIA M FIGUEROA et. al. One health outlook 2021-05-24
431 The Impact of Malaria Coinfection on Ebola Virus Disease Outcomes: A Systematic Review and Meta-analysis
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Abstract: Viral outbreaks present a particular challenge in countries in Africa where there is already a high incidence of other infectious diseases, including malaria which can alter …		 HANNAH M EDWARDS et. al. PloS one 2021-05-24
432 TRIM25 and ZAP Target The Ebola Virus Ribonucleoprotein Complex to Mediate Interferon-induced Restriction
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Highlight: We propose that TRIM25 targets the EBOV vRNP, exposing CpG-rich viral RNA species to restriction by ZAP.		 R. P. GALAO et. al. bio.microbiology 2021-05-24
433 Ebola Virus Glycoprotein Domains Associated with Protective Efficacy
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Highlight: Here, we analyzed if EBOV GP can be truncated to be less immunogenic yet still able to drive replication of the vaccine vector.		 B. Bhatia; W. Furuyama; T. Hoenen; H. Feldmann; A. Marzi; bio.microbiology 2021-05-23
434 Green and Sensitive Spectrofluorimetric Determination of Remdesivir, An FDA Approved SARS-CoV-2 Candidate Antiviral; Application in Pharmaceutical Dosage Forms and Spiked Human Plasma
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Abstract: Fluorescence spectroscopy has gained much attention over the last few years. Its advantages cover both analytical performance as well as ecological greenness. The quality control …		 Heba Elmansi; Adel Ehab Ibrahim; Ibraam E Mikhail; Fathalla Belal; Analytical methods : advancing methods and applications 2021-05-21
435 Drug Combination Therapy for Emerging Viral Diseases
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Abstract: Effective therapeutics to combat emerging viral infections are an unmet need. Historically, treatments for chronic viral infections with single drugs have not been successful, as …		 Zeenat A Shyr; Yu-Shan Cheng; Donald C Lo; Wei Zheng; Drug discovery today 2021-05-21
436 Associations Between Antibody Fc-Mediated Effector Functions and Long-Term Sequelae in Ebola Virus Survivors
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Abstract: Antibodies that mediate non-neutralizing functions play an important role in the immune response to Ebola virus (EBOV) and are thought to impact disease outcome. EBOV has also …		 DOMINIC PAQUIN-PROULX et. al. Frontiers in immunology 2021-05-20
437 Reflections on 40 Years of AIDS
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Abstract: June 2021 marks the 40th anniversary of the first description of AIDS. On the 30th anniversary, we defined priorities as improving use of existing interventions, clarifying …		 Kevin M De Cock; Harold W Jaffe; James W Curran; Emerging infectious diseases 2021-05-20
438 Designing Two Synthetic Constructs for Real Time PCR Detection of Francisella Tularensis and Ebola Virus
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Abstract: Generally, timely diagnosis of micro-organisms is very important to prevent many diseases. Many methods can detect micro-organisms like culture-based methods and molecular …		 Mohammadjavad Dehghan Esmat Abadi; Hesam Motalebzadeh; Mahmoud Barati; Mohammadali Yaghobi; Avicenna journal of medical biotechnology 2021-05-20
439 A Comparative NLP-Based Study on The Current Trends and Future Directions in COVID-19 Research
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Abstract: COVID-19 is a global health crisis that has altered human life and still promises to create ripples of death and destruction in its wake. The sea of scientific literature …		 Priyankar Bose; Satyaki Roy; Preetam Ghosh; IEEE access : practical innovations, open solutions 2021-05-20
440 Ebola Virus IgG Seroprevalence in Southern Mali
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Abstract: Mali had 2 reported introductions of Ebola virus (EBOV) during the 2013-2016 West Africa epidemic. Previously, no evidence for EBOV circulation was reported in Mali. We performed …		 SIDY BANE et. al. Emerging infectious diseases 2021-05-20
441 Novel Application of Capture-recapture Methods to Estimate The Completeness of Contact Tracing During A Large Outbreak of Ebola Virus Disease, Democratic Republic of Congo, 2018-2020
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Highlight: We estimated the sensitivity of CT by applying unilist capture-recapture methods on data from the 2018-2020 outbreak of Ebola virus disease in the Democratic Republic of Congo.		 J. A. POLONSKY et. al. med.epidemiology 2021-05-20
442 Immunological Analysis of The Murine Anti-CD3-induced Cytokine Release Syndrome Model and Therapeutic Efficacy of Anti-cytokine Antibodies
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Abstract: The aberrant release of inflammatory mediators often referred to as a cytokine storm or cytokine release syndrome (CRS), is a common and sometimes fatal complication in acute …		 LISE NOUVEAU et. al. European journal of immunology 2021-05-19
443 Cuba: Solidarity, Ebola and COVID-19
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 Angel A Escobedo; Cristians Auza-Santiváñez; Raisa Rumbaut; Maurizio Bonati; Imti Choonara; BMJ paediatrics open 2021-05-19
444 Ethical and Sociocultural Challenges in Managing Dead Bodies During Epidemics and Natural Disasters
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Abstract: Catastrophic natural disasters and epidemics claim thousands of lives and have severe and lasting consequences, accompanied by human suffering. The Ebola epidemic of 2014-2016 and …		 Halina Suwalowska; Fatu Amara; Nia Roberts; Patricia Kingori; BMJ global health 2021-05-18
445 Viral Interactions with Adaptor-Protein Complexes: A Ubiquitous Trait Among Viral Species
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Abstract: Numerous viruses hijack cellular protein trafficking pathways to mediate cell entry or to rearrange membrane structures thereby promoting viral replication and antagonizing the …		 IVANA STRAZIC GELJIC et. al. International journal of molecular sciences 2021-05-17
446 Pooled Analysis of The Accuracy of Xpert Ebola Assay for Diagnosing Ebola Virus Infection
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Abstract: West Africa has witnessed the unprecedented outbreak of Ebola virus disease (EVD). The Ebola virus (EBOV) can cause Ebola hemorrhagic fever, which is documented as the most deadly …		 ZHI-YONG PAN et. al. BioMed research international 2021-05-17
447 Retention of Healthcare Workers 1 Year After Recruitment and Deployment in Rural Settings: An Experience Post-Ebola in Five Health Districts in Guinea
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Abstract: Guinea undertook health workforce reform in 2016 following the Ebola outbreak to overcome decades-long shortages and maldistribution of healthcare workers (HCWs). Specifically, …		 DELPHIN KOLIE et. al. Human resources for health 2021-05-17
448 Ebolabase: Zaire Ebolavirus-human Protein Interaction Database for Drug-repurposing
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Abstract: Ebola Virus (EBOV) is one of the deadliest pathogenic virus which causes hemorrhagic fever. Though many Ebola-human interaction studies and databases are already reported, the …		 Mathavan Muthaiyan; Leimarembi Devi Naorem; Vassavi Seenappa; Shilpa Sri Pushan; Amouda Venkatesan; International journal of biological macromolecules 2021-05-17
449 Remdesivir Treatment for COVID 19 in Pregnant Patients with Moderate to Severe Symptoms: Serial Case Report
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Abstract: Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) infection that causes Coronavirus Disease 2019 (COVID-19) has become a major health problem worldwide and been …		 Yudianto Budi Saroyo; Amanda Rumondang; Irene Sinta Febriana; Achmad Kemal Harzif; Rima Irwinda; Infectious disease reports 2021-05-17
450 Quantification of Cytokine Storms During Virus Infections
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Abstract: Highly pathogenic virus infections usually trigger cytokine storms, which may have adverse effects on vital organs and result in high mortalities. The two cytokines interleukin …		 SHU YUAN et. al. Frontiers in immunology 2021-05-17
451 Longitudinal in Vivo Imaging of Acute Neuropathology in A Monkey Model of Ebola Virus Infection
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Abstract: Ebola virus (EBOV) causes neurological symptoms yet its effects on the central nervous system (CNS) are not well-described. Here, we longitudinally assess the acute effects of …		 WILLIAM SCHREIBER-STAINTHORP et. al. Nature communications 2021-05-17
452 Compelling Evidence for The Activity of Antiviral Peptides Against SARS-CoV-2
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Abstract: Multiple outbreaks of epidemic and pandemic viral diseases have occurred in the last 20 years, including those caused by Ebola virus, Zika virus, and severe acute respiratory …		 Miray Tonk; Daniel Růžek; Andreas Vilcinskas; Viruses 2021-05-14
453 Retrospective Study of Clinical Characteristics and Viral Etiologies of Patients with Viral Pneumonia in Beijing
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Abstract: The virus is common in patients with viral pneumonia. However, the viral etiology and clinical features of patients with viral pneumonia in China remain unclear. The main purpose …		 XIANG ZHAO et. al. Pulmonary circulation 2021-05-14
454 Glucosidase Inhibitors Suppress SARS-CoV-2 in Tissue Culture and May Potentiate
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Highlight: Here we report that the imino sugar glucosidase inhibitors, N-butyl deoxynojirimycin (NBDNJ), which is approved for management of lysosomal storage disease (sold as Zavesca), and ureido-N-hexyl deoxynojirimycine (BSBI-19029), suppress the replication of SARS-ncCoV-2/USA/WA1/2020 strain, in tissue culture.		 H. REYES et. al. bio.microbiology 2021-05-14
455 Structural Insights Into The Interaction of Filovirus Glycoproteins with The Endosomal Receptor Niemann-Pick C1: A Computational Study
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Abstract: Filoviruses, including marburgviruses and ebolaviruses, have a single transmembrane glycoprotein (GP) that facilitates their entry into cells. During entry, GP needs to be cleaved …		 Manabu Igarashi; Takatsugu Hirokawa; Yoshihiro Takadate; Ayato Takada; Viruses 2021-05-14
456 Barriers and Facilitators to Reporting Deaths Following Ebola Surveillance in Sierra Leone: Implications for Sustainable Mortality Surveillance Based on An Exploratory Qualitative Assessment
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Abstract: To understand the barriers contributing to the more than threefold decline in the number of deaths (of all causes) reported to a national toll free telephone line (1-1-7) after …		 MOHAMED F JALLOH et. al. BMJ open 2021-05-13
457 Multi-population Stochastic Modeling of Ebola in Sierra Leone: Investigation of Spatial Heterogeneity
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Abstract: A major outbreak of the Ebola virus occurred in 2014 in Sierra Leone. We investigate the spatial heterogeneity of the outbreak among districts in Sierra Leone. The stochastic …		 Rachid Muleia; Marc Aerts; Christel Faes; PloS one 2021-05-13
458 Colonial Virus: COVID-19, Creative Arts and Public Health Communication in Ghana
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Abstract: Since March 2020, Ghana’s creative arts communities have tracked the complex facets of the COVID-19 pandemic through various art forms. This paper reports a study that analysed …		 Ama de-Graft Aikins; Bernard Akoi-Jackson; Ghana medical journal 2021-05-12
459 Highly Sensitive Point-of-Care Ebola Diagnostic In Development
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 Jennifer Abbasi; JAMA 2021-05-11
460 Single-component Multilayered Self-assembling Nanoparticles Presenting Rationally Designed Glycoprotein Trimers As Ebola Virus Vaccines
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Abstract: Ebola virus (EBOV) glycoprotein (GP) can be recognized by neutralizing antibodies (NAbs) and is the main target for vaccine design. Here, we first investigate the contribution of …		 LINLING HE et. al. Nature communications 2021-05-11
461 Editorial: The Pathogenesis of Long-Term Neuropsychiatric COVID-19 and The Role of Microglia, Mitochondria, and Persistent Neuroinflammation: A Hypothesis
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Abstract: Persistent comorbidities occur in patients who initially recover from acute coronavirus disease 2019 (COVID-19) due to infection with severe acute respiratory syndrome coronavirus …		 GEORGE B STEFANO et. al. Medical science monitor : international medical journal of … 2021-05-10
462 Fear and Stigma Remain in Survivors of Africa’s Ebola Epidemic
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 Paul Adepoju; BMJ (Clinical research ed.) 2021-05-10
463 Is Guinea Meeting The Challenges to Control The New Ebola Virus Disease Outbreak in West Africa?
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 Alexandre Delamou; Mory Keita; Abdoul Habib Beavogui; Alioune Camara; Wim Van Damme; Preventive medicine reports 2021-05-10
464 A Multi-stage Stochastic Programming Approach to Epidemic Resource Allocation with Equity Considerations
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Abstract: Existing compartmental models in epidemiology are limited in terms of optimizing the resource allocation to control an epidemic outbreak under disease growth uncertainty. In this …		 Xuecheng Yin; I E Büyüktahtakın; Health care management science 2021-05-10
465 Impacts of Health-related School Closures on Child Protection Outcomes: A Review of Evidence from Past Pandemics and Epidemics and Lessons Learned for COVID-19
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Abstract: Through a rapid review drawing on pandemics and epidemics with associated school closures, this article aims to understand first, the state of the evidence on impacts of school …		 Cirenia Chavez Villegas; Silvia Peirolo; Matilde Rocca; Alessandra Ipince; Shivit Bakrania; International journal of educational development 2021-05-09
466 Dual-axis Volta Phase Plate Cryo-electron Tomography of Ebola Virus-like Particles Reveals Actin-VP40 Interactions
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Abstract: Cryo-electron tomography (cryo-ET) is a pivotal imaging technique for studying the structure of pleomorphic enveloped viruses and their interactions with the host at native …		 Sophie L Winter; Petr Chlanda; Journal of structural biology 2021-05-08
467 InterARTIC: An Interactive Web Application for Whole-genome Nanopore Sequencing Analysis of SARS-CoV-2 and Other Viruses
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Highlight: Worked example: We demonstrate the use of InterARTIC for the analysis of ONT viral WGS data from SARS-CoV-2 and Ebola virus, using a laptop computer or the internal computer on an ONT GridION sequencing device.		 J. M. FERGUSON et. al. bio.bioinformatics 2021-05-06
468 The Methyltransferase Domain of The Respiratory Syncytial Virus L Protein Catalyzes Cap N7 and 2′-O-methylation
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Abstract: Respiratory syncytial virus (RSV) is a negative sense single-stranded RNA virus and one of the main causes of severe lower respiratory tract infections in infants and young …		 PRISCILA SUTTO-ORTIZ et. al. PLoS pathogens 2021-05-06
469 Building The Sierra Leone Ebola Database: Organization and Characteristics of Data Systematically Collected During 2014-2015 Ebola Epidemic
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Abstract: During the 2014-2016 Ebola outbreak in West Africa, the Sierra Leone Ministry of Health and Sanitation (MoHS), the US Centers for Disease Control and Prevention, and responding …		 SACHIN AGNIHOTRI et. al. Annals of epidemiology 2021-05-06
470 African Based Researchers’ Output on Models for The Transmission Dynamics of Infectious Diseases and Public Health Interventions: A Scoping Review
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Abstract: Applied epidemiological models are used in predicting future trends of diseases, for the basic understanding of disease and health dynamics, and to improve the measurement of …		 Olatunji O Adetokunboh; Zinhle E Mthombothi; Emanuel M Dominic; Sylvie Djomba-Njankou; Juliet R C Pulliam; PloS one 2021-05-06
471 Ebola
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 Robert J Leggiadro; The Pediatric infectious disease journal 2021-05-06
472 Development of A New Reverse Genetics System for Ebola Virus
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Abstract: Ebola virus (EBOV) is a highly pathogenic negative-stranded RNA virus that has caused several deadly endemics in the past decades. EBOV reverse genetics systems are available for …		 TIANYU GAN et. al. mSphere 2021-05-05
473 Bioreactor Production of RVSV-based Vectors in Vero Cell Suspension Cultures
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Abstract: The Vero cell line is the most used continuous cell line in viral vaccine manufacturing. This adherent cell culture platform requires the use of surfaces to support cell growth, …		 Sascha Kiesslich; Gyoung N Kim; Chun F Shen; C Yong Kang; Amine A Kamen; Biotechnology and bioengineering 2021-05-05
474 Investigating The Circulation of Ebola Viruses in Bats During The Ebola Virus Disease Outbreaks in The Equateur and North Kivu Provinces of The Democratic Republic of Congo from 2018
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Abstract: With 12 of the 31 outbreaks, the Democratic Republic of Congo (DRC) is highly affected by Ebolavirus disease (EVD). To better understand the role of bats in the ecology of Ebola …		 AUDREY LACROIX et. al. Pathogens (Basel, Switzerland) 2021-05-04
475 Editorial: MRNA Vaccines and Future Epidemic, Pandemic, and Endemic Zoonotic Virus Infections
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Abstract: There have been rapid developments in safe and effective mRNA vaccines for zoonotic infections in the past year. Years of research have made these advances possible, leading to in …		 Dinah V Parums; Medical science monitor : international medical journal of … 2021-05-04
476 Engineered Human Monoclonal ScFv to Receptor Binding Domain of Ebolavirus
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Abstract: (1) Background: (EBOV) poses as a significant threat for human health by frequently causing epidemics of the highly contagious Ebola virus disease (EVD). EBOV glycoprotein (GP), …		 JASLAN DENSUMITE et. al. Vaccines 2021-05-04
477 Simultaneous Detection of Marburg Virus and Ebola Virus with TaqMan-based Multiplex Real-time PCR Method
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Abstract: Marburg virus (MARV) and Ebola virus (EBOV) are acute infections with high case fatality rates. It is of great significance for epidemic monitoring and prevention and control of …		 Zhikang Yu; Heming Wu; Qingyan Huang; Zhixiong Zhong; Journal of clinical laboratory analysis 2021-05-03
478 Protective Pan-ebolavirus Combination Therapy By Two Multifunctional Human Antibodies
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Highlight: Here we report the development of a therapeutic cocktail comprising two broadly neutralizing human antibodies rEBOV-515 and rEBOV-442 that recognize non-overlapping sites on the ebolavirus glycoprotein (GP). This study provides advanced preclinical data to support clinical development of this cocktail for pan-ebolavirus therapy.		 P. GILCHUK et. al. bio.immunology 2021-05-02
479 The Impact of Past Pandemics on Economic and Gender Inequalities
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Highlight: We consider the impact of six major pandemic episodes – H3N2 Flu (1968), SARS (2003), H1N1 Swine Flu (2009), MERS (2012), Ebola (2014), and Zika (2016) – on cross-country inequalities in a sample of up to 180 countries observed over 1950-2019.		 M. Brzezinski; med.health-economics 2021-05-01
480 Understanding Varying COVID-19 Mortality Rates Reported in Africa Compared to Europe, Americas and Asia
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Abstract: The SARS-CoV-2 infection, which causes the COVID-19 disease, has impacted every nation on the globe, albeit disproportionately. African countries have seen lower infection and …		 Emeka Francis Okonji; Osaretin Christabel Okonji; Ferdinand C Mukumbang; Brian Van Wyk; Tropical medicine & international health : TM & IH 2021-05-01
481 Understanding Misinformation Infodemic During Public Health Emergencies Due to Large-scale Disease Outbreaks: A Rapid Review
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Abstract: The coronavirus disease 2019 (COVID-19) has caused hundreds of thousands of deaths, impacted the flow of life and resulted in an immeasurable amount of socio-economic damage. …		 Nashit Chowdhury; Ayisha Khalid; Tanvir C Turin; Zeitschrift fur Gesundheitswissenschaften = Journal of … 2021-05-01
482 Defective Interfering Genomes and The Full-Length Viral Genome Trigger RIG-I After Infection With Vesicular Stomatitis Virus in A Replication Dependent Manner
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Abstract: Replication competent vesicular stomatitis virus (VSV) is the basis of a vaccine against Ebola and VSV strains are developed as oncolytic viruses. Both functions depend on the …		 ANDREAS LINDER et. al. Frontiers in immunology 2021-04-30
483 Individually Optimal Choices Can Be Collectively Disastrous in COVID-19 Disease Control
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Abstract: The word ‘pandemic’ conjures dystopian images of bodies stacked in the streets and societies on the brink of collapse. Despite this frightening picture, denialism and …		 MADISON STODDARD et. al. BMC public health 2021-04-30
484 Non-epistemic Values in Shaping The Parameters for Evaluating The Effectiveness of Candidate Vaccines: The Case of An Ebola Vaccine Trial
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Abstract: This paper examines the case of Ebola, ça Suffit trial which was conducted in Guinea during Ebola Virus Disease (EVD) outbreak in 2015. I demonstrate that various non-epistemic …		 Joby Varghese; History and philosophy of the life sciences 2021-04-29
485 Prioritization of Zoonotic Diseases of Public Health Significance in Nigeria Using The One-health Approach
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Abstract: Nigeria, with a population of over 190 million people, is rated among the 10 countries with the highest burden of infectious and zoonotic diseases globally. In Nigeria, there …		 CHIKWE IHEKWEAZU et. al. One health (Amsterdam, Netherlands) 2021-04-28
486 From Bad to Worse: Airline Boarding Changes in Response to COVID-19
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Abstract: Airlines have introduced a back-to-front boarding process in response to the COVID-19 pandemic. It is motivated by the desire to reduce passengers’ likelihood of passing close to …		 T ISLAM et. al. Royal Society open science 2021-04-28
487 Responding to The 2018-2020 Ebola Virus Outbreak in The Democratic Republic of The Congo: Rethinking Humanitarian Approaches
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Abstract: The Democratic Republic of Congo (DRC) presents a challenging context in which to respond to public health crises. Its 2018-2020 Ebola outbreak was the second largest in history. …		 SUSANNAH H MAYHEW et. al. Risk management and healthcare policy 2021-04-28
488 Chikungunya-specific IgG and Neutralizing Antibody Responses in Natural Infection of Chikungunya Virus in Children from India
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Abstract: Chikungunya virus (CHIKV) infection is endemic in many different countries. CHIKV outbreaks are emerging in new areas and re-emerging in previously exposed geographical regions, …		 ANIL VERMA et. al. Archives of virology 2021-04-27
489 Inaccuracies in Google’s Health-Based Knowledge Panels Perpetuate Widespread Misconceptions Involving Infectious Disease Transmission
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Abstract: Google health-based Knowledge Panels were designed to provide users with high-quality basic medical information on a specific condition. However, any errors contained within …		 Andrew D Haddow; Sarah C Clarke; The American journal of tropical medicine and hygiene 2021-04-26
490 Analysis of Viral RNA-host Protein Interactomes Enables Rapid Antiviral Drug Discovery
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Highlight: Here we applied ChIRP-MS to profile the interactomes of human proteins and the RNA genomes of SARS-CoV-2, EBOV, and ZIKV in infected cells.		 S. ZHANG et. al. bio.microbiology 2021-04-26
491 Consequences of School Closure on Access to Education: Lessons from The 2013-2016 Ebola Pandemic
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Abstract: The COVID-19 pandemic has seen an unprecedented shutdown of society. Among the various safety measures taken, much attention has been given to school closure as a …		 William C Smith; International review of education. Internationale … 2021-04-26
492 The Sharing of Research Data Facing The COVID-19 Pandemic
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Abstract: During the previous Ebola and Zika outbreaks, researchers shared their data, allowing many published epidemiological studies to be produced only from open research data, to speed …		 Rut Lucas-Dominguez; Adolfo Alonso-Arroyo; Antonio Vidal-Infer; Rafael Aleixandre-Benavent; Scientometrics 2021-04-26
493 Ebola Virus Disease Outbreak in The Republic of Guinea 2021: Hypotheses of Origin
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Highlight: This paper considers various hypotheses of its emergence.		 A. A. KRITSKY et. al. bio.microbiology 2021-04-23
494 Marburg and Ebola Virus MRNA 3 Untranslated Regions Contain Negative Regulators of Translation That Are Modulated By ADAR1 Editing
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Abstract: The filovirus family includes deadly pathogens such as Ebola virus (EBOV) and Marburg virus (MARV). A substantial portion of filovirus genomes encode 5 and 3 untranslated regions …		 S. Khadka; C. G. Williams; J. Sweeney-Gibbons; C. F. Basler; bio.microbiology 2021-04-22
495 Systems Biological Assessment of Human Immunity to BNT162b2 MRNA Vaccination
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Abstract: The emergency use authorization of two COVID-19 mRNA vaccines in less than a year since the emergence of SARS-CoV-2, represents a landmark in vaccinology1,2. Yet, how mRNA …		 Bali Pulendran; Prabhu S Arunachalam; Research square 2021-04-22
496 A Perfect Storm? Health Anxiety, Contamination Fears, and COVID-19: Lessons Learned from Past Pandemics and Current Challenges
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Abstract: The novel coronavirus disease 2019 (COVID-19) rapidly spread, becoming a global pandemic with significant health, economic, and social impacts. COVID-19 has caused widespread …		 Danielle Dennis; Cynthia Radnitz; Michael G Wheaton; International journal of cognitive therapy 2021-04-22
497 Role of Participatory Health Informatics in Detecting and Managing Pandemics: Literature Review
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Abstract: Using participatory health informatics (PHI) to detect disease outbreaks or learn about pandemics has gained interest in recent years. However, the role of PHI in understanding …		 Elia Gabarron; Octavio Rivera-Romero; Talya Miron-Shatz; Rebecca Grainger; Kerstin Denecke; Yearbook of medical informatics 2021-04-21
498 Dual-axis Volta Phase Plate Cryo-electron Tomography of Ebola Virus-like Particles Reveals Actin-VP40 Interactions
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Highlight: Here, we compare dual-axis cryo-ET with and without VPP on Ebola virus-like particles to visualize and segment viral and host cell proteins within the membrane-enveloped filamentous particles.		 S. L. Winter; P. Chlanda; bio.biophysics 2021-04-21
499 Ebola Zaire Vaccine Live
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 American journal of health-system pharmacy : AJHP : … 2021-04-21
500 The COVID-19 Medicine Remdesivir Is Therapeutically Activated By Carboxylesterase-1 AND Excessive Hydrolysis Increases Cytotoxicity
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Abstract: The pandemic of coronavirus disease 2019 (COVID-19) has become a global health crisis with the death toll of over 14 million people. So far, there are limited options to treat …		 Yue Shen; William Eades; Bingfang Yan; Hepatology communications 2021-04-21
501 Surface Disinfection Using Ultraviolet Lightwith A Mobile Manipulation Robot
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Abstract: Robots are being increasingly used in the fight against highly-infectious diseases such as Ebola, MERS, and SARS-COV-2. Many of the robots that are being used employ ultraviolet …		 Alan G Sanchez; William D Smart; ArXiv 2021-04-21
502 The Impact of The COVID-19 Pandemic on Health Service Utilisation in Sierra Leone
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Highlight: This study examines the effects of COVID-19 on health service utilisation in a sub-Saharan country, Sierra Leone.		 S. SEVALIE et. al. med.infectious-diseases 2021-04-19
503 Neutralizing Monoclonal Antibodies for Treatment of COVID-19
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Abstract: Several neutralizing monoclonal antibodies (mAbs) to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been developed and are now under evaluation in clinical …		 PETER C TAYLOR et. al. Nature reviews. Immunology 2021-04-19
504 SARS-CoV-2 M Pro : A Potential Target for Peptidomimetics and Small-Molecule Inhibitors
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Abstract: The uncontrolled spread of the COVID-19 pandemic caused by the new coronavirus SARS-CoV-2 during 2020-2021 is one of the most devastating events in the history, with remarkable …		 Andrea Citarella; Angela Scala; Anna Piperno; Nicola Micale; Biomolecules 2021-04-19
505 Addressing COVID-19 Vulnerabilities: How Do We Achieve Global Health Security in An Inequitable World
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Abstract: The spread of the serve acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes COVID-19, [WHO. (2019). . …		 Annamarie Bindenagel Šehović; Kaymarlin Govender; Global public health 2021-04-18
506 Ebola Virus Disease: Current Vaccine Solutions
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Abstract: Ebola Virus Disease (EVD) is an emerging zoonotic disease with intermittent outbreaks in Central and West African countries. The unpredictable high case fatality rate has made it …		 Oyewale Tomori; Matthew Olatunji Kolawole; Current opinion in immunology 2021-04-17
507 Therapeutic Use of Convalescent Plasma in COVID-19 Infected Patients with Concomitant Hematological Disorders
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Abstract: The use of convalescent plasma (CP) from individuals recovered from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a promising therapeutic modality for the …		 Francesco Lanza; Vanessa Agostini; Federica Monaco; Francesco Passamonti; Jerard Seghatchian; Clinical hematology international 2021-04-16
508 Identification of Novel Antiviral Compounds Targeting Entry of Hantaviruses
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Abstract: Hemorrhagic fever viruses, among them orthohantaviruses, arenaviruses and filoviruses, are responsible for some of the most severe human diseases and represent a serious challenge …		 Jennifer Mayor; Giulia Torriani; Olivier Engler; Sylvia Rothenberger; Viruses 2021-04-16
509 An Unprecedented Genomic Analysis Helped to Curb An Ebola Outbreak
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 Nature 2021-04-16
510 Using Digital Surveillance Tools for Near Real-time Mapping of The Risk of Infectious Disease Spread
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Abstract: Data from digital disease surveillance tools such as ProMED and HealthMap can complement the field surveillance during ongoing outbreaks. Our aim was to investigate the use of …		 SANGEETA BHATIA et. al. NPJ digital medicine 2021-04-16
511 Lessons Learned from Implementation of A National Hotline for Ebola Virus Disease Emergency Preparedness in South Sudan
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Abstract: The world’s second largest Ebola outbreak occurred in the Democratic Republic of Congo from 2018 to 2020. At the time, risk of cross-border spread into South Sudan was very high. …		 VELMA K LOPEZ et. al. Conflict and health 2021-04-15
512 COVID-19 Preparedness at Health Facilities and Community Service Points Serving People Living with HIV in Sierra Leone
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Abstract: After a decade of civil war and the 2014-2016 West African Ebola outbreak, Sierra Leone now faces the COVID-19 pandemic with a fragile health system. As was demonstrated during …		 LAUREN E PARMLEY et. al. PloS one 2021-04-15
513 Developmental Landscape of Potential Vaccine Candidates Based on Viral Vector for Prophylaxis of COVID-19
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Abstract: Severe acute respiratory syndrome coronavirus 2, SARS-CoV-2, arose at the end of 2019 as a zoonotic virus, which is the causative agent of the novel coronavirus outbreak COVID-19. …		 RAJASHRI BEZBARUAH et. al. Frontiers in molecular biosciences 2021-04-15
514 An Overview of Proteomic Methods for The Study of ‘cytokine Storms’
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Abstract: : The cytokine storm is a form of excessive systemic inflammatory reaction triggered by a myriad of factors that may lead to multi-organ failure, and finally to death. The …		 Paul David; Frederik J Hansen; Adil Bhat; Georg F Weber; Expert review of proteomics 2021-04-14
515 Antibody Affinity As A Driver of Signal Generation in A Paper-based Immunoassay for Ebola Virus Surveillance
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Abstract: During epidemics, such as the frequent and devastating Ebola virus outbreaks that have historically plagued regions of Africa, serological surveillance efforts are critical for …		 Lara P Murray; Ramesh Govindan; Andrea C Mora; James B Munro; Charles R Mace; Analytical and bioanalytical chemistry 2021-04-14
516 Why Is Repositioning Public Health Innovation Towards A Social Paradigm Necessary? A Reflection on The Field of Public Health Through The Examples of Ebola and Covid-19
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Abstract: Health innovations are generally oriented on a techno-economic vision. In this perspective, technologies are seen as an end in themselves, and there is no arrangement between the …		 Marietou Niang; Sophie Dupéré; Hassane Alami; Marie-Pierre Gagnon; Globalization and health 2021-04-14
517 Old Treatment for A New Disease: Can Rectal Ozone Insufflation Be Used for COVID-19 Management? A Case Report
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Abstract: COVID-19 is a newly discovered deadly disease with no proven definitive treatment until now. It is now proved that it can affect different body organs which necessitate intensive …		 Hamdy A Hendawy; Walid Mosallam; Mohamed E Abuelnaga; Amr M Sabry; SN comprehensive clinical medicine 2021-04-14
518 Ebola Outbreak Amid COVID-19 in The Republic of Guinea: Priorities for Achieving Control
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Abstract: In February 2021, a new Ebola outbreak occurred amid the coronavirus disease 2019 (COVID-19) pandemic in the Republic of Guinea. Technical committees and Ebola mitigation …		 ABDULLAHI TUNDE ABORODE et. al. The American journal of tropical medicine and hygiene 2021-04-14
519 Broad-Spectrum Antiviral Strategies and Nucleoside Analogues
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