Shire: Clinical Trials

88 trials sponsored by Shire, newest first

ClinicalTrials Daily · Areas · Conditions · Drugs · Sponsors ·

74 completed, 10 terminated, 2 active not recruiting, 2 withdrawn. 88 Phase 2, 11 Phase 1, 7 Phase 3.

By phase and status

Phase	Trials	Status
Phase 2	88	Completed 74, Terminated 10, Active not recruiting 2, Withdrawn 2
Phase 1	11	Completed 10, Terminated 1
Phase 3	7	Completed 6, Withdrawn 1

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Trials (filtered) newest first · largest first

All 88 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
Study of rADAMTS-13 (SHP655) in the Treatment of Participants With Acquired Thrombotic Thrombocytopenic Purpura (aTTP) Placebo, SHP655, Standard of Care - Acquired Thrombotic Thrombocytopenic Purpura (aTTP)	Phase 2	Completed	Shire	28	2019-10-09	2022-12-01
A Study of Intrathecal SHP611 in Children With Metachromatic Leukodystrophy SHP611 - Metachromatic Leukodystrophy (MLD)	Phase 2	Completed	Shire	36	2019-05-13	2026-07-10
Nal-iri/lv5-fu Versus Paclitaxel as Second Line Therapy in Patients With Metastatic Oesophageal Squamous Cell Carcinoma Onivyde, Paclitaxel - Squamous Cell Carcinoma	Phase 2	Completed	Federation Francophone de Cancerologie Digestive	106	2019-03-07	2025-01-08
Shire SCT: Lisdexamfetamine Treatment for ADHD and SCT Lisdexamfetamine, Placebo - Attention Deficit Disorder, Attention Deficit Hyperactivity Disorder	Phase 2	Completed	NYU Langone Health	38	2015-11-01	2021-11-16
Aralast NP in Islet Transplant Alpha-1 Antitrypsin - Type 1 Diabetes Mellitus	Phase 1 / Phase 2	Completed	University of Alberta	5	2015-08-01	2022-05-24
Safety, Tolerability, Pharmacokinetic, and Efficacy Study of SPD489 in Preschool Children With Attention-deficit/Hyperactivity Disorder SPD489 - Attention Deficit Hyperactivity Disorder (ADHD)	Phase 2	Completed	Shire	24	2015-04-15	2021-06-08
Study of Long Term Safety and Clinical Outcomes of Idursulfase IT and Elaprase Treatment in Pediatric Participants Who Have Completed Study HGT-HIT-094 Idursulfase-IT, Elaprase - Hunter Syndrome	Phase 2 / Phase 3	Completed	Shire	56	2015-04-14	2025-06-19
An Extension Study to Determine Safety and Efficacy for Pediatric Patients With MPS Type IIIA Disease Who Participated in Study HGT-SAN-093. HGT-1410 - Sanfilippo Syndrome, Mucopolysaccharidosis (MPS)	Phase 2	Terminated	Shire	17	2015-04-08	2021-06-11
Long-term Safety and Efficacy Outcome Study Comparing Children Previously Enrolled in Study ROPP-2008-01 for the Prevention of Retinopathy of Prematurity (ROP) rhIGF-1/rhIGFBP-3 - Retinopathy of Prematurity (ROP)	Phase 2	Completed	Shire	76	2015-03-26	2022-05-18
Treatment of Iron Overload Requiring Chelation Therapy SPD602, Deferasirox - Transfusional Iron Overload, Iron Overload	Phase 2	Withdrawn	Shire		2014-11-20	2021-06-02
A Study to Determine the Effects of NPSP795 on the Calcium-sensing Receptor in Subjects With Autosomal Dominant Hypocalcemia as Measured by PTH Levels and Blood Calcium Concentrations NPSP795 - Autosomal Dominant Hypocalcemia (ADH)	Phase 2	Completed	Shire	7	2014-07-18	2021-08-09
Study of Intrathecal Idursulfase-IT Administered in Conjunction With Elaprase® in Pediatric Patients With Hunter Syndrome and Early Cognitive Impairment idursulfase-IT, No IT treatment - Hunter Syndrome	Phase 2 / Phase 3	Completed	Shire	58	2014-03-24	2021-06-11
Randomized, Controlled, Open-label, Multicenter, Safety and Efficacy Study of rhHNS Administration Via an IDDD in Pediatric Patients With Early Stage MPS IIIA Disease Recombinant human heparan N-sulfatase [rhHNS] - Sanfilippo Syndrome	Phase 2	Completed	Shire	21	2014-02-26	2021-06-08
A Novel "Pediatric-Inspired" Regimen With Reduced Myelosuppressive Drugs for Adults (Aged 18-60) With Newly Diagnosed Ph Negative Acute Lymphoblastic Leukemia Daunorubicin, Vincristine, Prednisone - Leukemia	Phase 2	Active not recruiting	Memorial Sloan Kettering Cancer Center	39	2013-08-07	2026-09-15
An Efficacy and Safety Study of HGT-1110 in Participants With Metachromatic Leukodystrophy HGT-1110 - Metachromatic Leukodystrophy (MLD)	Phase 1 / Phase 2	Completed	Shire	24	2013-05-23	2026-04-21
FST-100 in the Treatment of Acute Viral Conjunctivitis FST-100, FST-100 Vehicle - Acute Viral Conjunctivitis	Phase 2	Completed	Shire	132	2013-05-17	2021-06-24
An Efficacy and Safety Study of SRM003 in the Treatment of Subjects Undergoing Placement of an Arteriovenous Graft to Facilitate Hemodialysis Access SRM003, Participating Site's standard practice - Arteriovenous Graft	Phase 2	Terminated	Shire	32	2013-03-28	2021-06-08
An Efficacy and Safety Study of SRM003 in the Treatment of Subjects Undergoing Creation of an Arteriovenous Fistula to Facilitate Hemodialysis Access SRM003, Participating Site's standard practice - Arteriovenous Fistula	Phase 2	Completed	Shire	64	2013-03-26	2021-06-08
Long-Term Safety Of PF-00547659 In Ulcerative Colitis 75mg SHP647 (PF-00547659), 225mg SHP647 (PF-00547659) - Ulcerative Colitis	Phase 2	Completed	Shire	330	2013-03-18	2021-06-03
A Study to Assess the Pharmacokinetics of Lanthanum Carbonate, Investigate and Compare the Efficacy, Safety and Tolerability of Lanthanum Carbonate With Calcium Carbonate in Hyperphosphataemic Children and Adolescents With Chronic Kidney Disease on Dialysis Lanthanum Carbonate, Calcium Carbonate - Chronic Kidney Disease, Hyperphosphatemia	Phase 2	Completed	Shire	63	2013-02-15	2021-06-10

Shire: Clinical Trials

88 trials sponsored by Shire, newest first

ClinicalTrials Daily · Areas · Conditions · Drugs · Sponsors ·

By phase and status

Trials (filtered) newest first · largest first

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