7 completed, 1 terminated, 1 withdrawn. 7 Phase 1, 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 7 | Completed 6, Terminated 1 |
| Phase 2 | 5 | Completed 4, Withdrawn 1 |
Follow Prism Pharma Co., Ltd.: new trials by email
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety and Effectiveness of PRI-724 for Hepatitis C or B Virus Derived Liver Cirrhosis PRI-724 - Hepatitis C, Hepatitis B | Phase 1 / Phase 2 | Completed | Kiminori Kimura, MD | 27 | 2018-07-24 | 2024-10-10 |
| Combination Chemotherapy and Bevacizumab With or Without PRI-724 in Treating Patients With Newly Diagnosed Metastatic Colorectal Cancer CBP/beta-catenin Antagonist PRI-724, Bevacizumab, Leucovorin Calcium - Colorectal Adenocarcinoma, Stage IVA Colorectal Cancer | Phase 2 | Withdrawn | University of Southern California | 2015-11-01 | 2017-04-17 | |
| Trial to Evaluate Topical C-82 in a Psoriasis Plaque Test C-82 Topical Gel, Placebo, C-82 Topical Gel, 1%, Daivonex cream - Psoriasis | Phase 1 / Phase 2 | Completed | Prism Pharma Co., Ltd. | 14 | 2015-06-01 | 2017-08-17 |
| Trial of Topical C-82 in Systemic Sclerosis - A Phase I/II Biomarker and Safety Trial C-82 Topical Gel, 1%, C-82 Topical Gel, Placebo - Systemic Scleroderma | Phase 1 / Phase 2 | Completed | Prism Pharma Co., Ltd. | 17 | 2015-06-01 | 2017-08-17 |
| A Follow-up Evaluation Study of PRI-724-1101 PRI-724 - Hepatitis C Virus-infected Cirrhosis | Completed | Komagome Hospital | 8 | 2014-12-18 | 2022-07-07 | |
| An Open Label, Single Arm, Dose Escalation Phase 1 Trial of PRI-724 in Patients With HCV-induced Cirrhosis PRI-724 - Hepatitis C Virus-infected Cirrhosis | Phase 1 | Completed | Komagome Hospital | 14 | 2014-08-01 | 2022-07-07 |
| Safety and Efficacy Study of PRI-724 Plus Gemcitabine in Subjects With Advanced or Metastatic Pancreatic Adenocarcinoma PRI-724 - Advanced Pancreatic Cancer, Metastatic Pancreatic Cancer | Phase 1 | Completed | Prism Pharma Co., Ltd. | 20 | 2013-04-01 | 2017-08-17 |
| Safety and Efficacy Study of PRI-724 in Subjects With Advanced Myeloid Malignancies PRI-724 - Acute Myeloid Leukemia, Chronic Myeloid Leukemia | Phase 1 / Phase 2 | Completed | Prism Pharma Co., Ltd. | 49 | 2012-07-01 | 2017-08-17 |
| Safety and Efficacy Study of PRI-724 in Subjects With Advanced Solid Tumors PRI-724 - Advanced Solid Tumors | Phase 1 | Terminated | Prism Pharma Co., Ltd. | 23 | 2011-02-01 | 2017-08-17 |
Hepatitis C (2) · Pancreatic Neoplasms (2) · Colonic Neoplasms (1) · Colorectal Neoplasms (1) · Fibrosis (1) · Hepatitis B (1) · Leukemia (1) · Leukemia, Myelogenous, Chronic, BCR-ABL Positive (1) · Leukemia, Myeloid, Acute (1) · Liver Cirrhosis (1) · Myelodysplastic Syndromes (1) · Neoplasm Metastasis (1) · Neoplasms (1) · Psoriasis (1) · Scleroderma, Diffuse (1)
ICG 001 (7) · Betamethasone (1) · Bevacizumab (1) · Fluorouracil (1) · Leucovorin (1) · Oxaliplatin (1) · calcipotriene (1)
United States (5) · Japan (3) · Germany (1)
Kiminori Kimura, MD (3) · Anthony El-Khoueiry, MD (1) · Elisabeth Theis, MD (1) · Heinz-Josef Lenz (1) · Jorge Cortes, MD (1) · Robert Lafyatis, MD (1) · Robert R. McWilliams, M.D. (1)
P30CA014089 (1), R01CA166161 (1)