8 completed, 4 unknown. 4 Phase 1, 3 Not applicable, 3 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Completed 3, Unknown 1 |
| Not applicable | 3 | Unknown 2, Completed 1 |
| Phase 2 | 3 | Completed 3 |
| Phase 3 | 1 | Completed 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Repurposing Bromocriptine for Abeta Metabolism in Alzheimer's Disease Bromocriptine Mesilate, Placebos - Familial Alzheimer Disease (FAD), PSEN1 Mutation | Phase 1 / Phase 2 | Completed | Kyoto University | 8 | 2020-06-05 | 2025-08-29 |
| Neuroinflammation During ICU-associated Delirium in Critically Ill Patients and Its Association With Structural and Functional Brain Alterations: a Nested Case-control Study Delirium, Critical Illness | Unknown | Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia | 60 | 2019-03-25 | 2019-09-06 | |
| Elucidate Vasodilatory Capacity From Histology-Defined Analysis of Coronary CT Angiography ElucidVivo - Vascular Diseases | Completed | Elucid Bioimaging Inc. | 302 | 2017-01-01 | 2022-09-08 | |
| Dynamic Stress Perfusion CT for Detection of Inducible Myocardial Ischemia Diagnostic detection of coronary artery disease - Coronary Artery Disease | Completed | Erasmus Medical Center | 180 | 2016-06-07 | 2020-12-11 | |
| Investigator Initiated Phase 1 Study of TBI-1301 TBI-1301, Cyclophosphamide, Fludarabine - Solid Tumors | Phase 1 | Unknown | Mie University | 9 | 2015-03-01 | 2018-10-24 |
| Evaluation of the Simplified Treat And Extend Regimen Using Ranibizumab in Exudative Age Related Macular Degeneration ranibizumab - Exudative Age-related Macular Degeneration | Not applicable | Unknown | Mie University | 50 | 2014-06-01 | 2014-12-31 |
| Investigator Initiated Phase 1 Study of TBI-1201 TBI-1201, Cyclophosphamide, Fludarabine - Solid Tumors | Phase 1 | Completed | Mie University | 18 | 2014-04-01 | 2021-06-18 |
| Predictive Factors of Ranibizumab Treatment in Macular Edema With CRVO Ranibizumab - Central Retinal Vein Occlusion | Not applicable | Unknown | Mie University | 30 | 2013-12-01 | 2014-03-19 |
| Carotid Artery Stenting With Cilostazol Addition for Restenosis Cilostazol or Non-Cilostazol - In-stent Restenosis After Carotid Artery Stenting | Not applicable | Completed | Kobe City General Hospital | 707 | 2010-12-01 | 2019-10-16 |
| Changes in Adrenal Hormones During Adrenal Radiofrequency Ablation Radiofrequency ablation - Adrenal Tumors | Phase 2 / Phase 3 | Completed | Mie University | 18 | 2009-10-01 | 2015-04-28 |
| Radiofrequency Ablation in Resectable Colorectal Lung Metastasis Lung radiofrequency ablation - Lung Metastasis, Colorectal Cancer | Phase 2 | Completed | Mie University | 70 | 2008-10-01 | 2019-03-07 |
| Safety and Immunogenicity of CHP-HER2 and CHP-NY-ESO-1 Protein With OK-432 in Antigen-Expressing Cancers CHP-HER2, CHP-NY-ESO-1 - Esophageal Cancer, Lung Cancer | Phase 1 | Completed | Ludwig Institute for Cancer Research | 9 | 2005-07-01 | 2009-03-03 |
Esophageal Neoplasms (3) · Ovarian Neoplasms (3) · Head and Neck Neoplasms (2) · Melanoma (2) · Adrenal Gland Neoplasms (1) · Alzheimer Disease (1) · Breast Neoplasms (1) · Carotid Artery Diseases (1) · Colorectal Neoplasms (1) · Coronary Artery Disease (1) · Critical Illness (1) · Delirium (1) · Lung Neoplasms (1) · Neuroinflammatory Diseases (1) · Retinal Vein Occlusion (1)
Cyclophosphamide (2) · Ranibizumab (2) · fludarabine (2) · fludarabine phosphate (2) · Bromocriptine (1) · Cilostazol (1) · Population Groups (1) · Radiofrequency Ablation (1)
Japan (9) · Italy (1) · Netherlands (1)
Hiroshi Shiku, M.D., Ph.D. (2) · Shinichi Kageyama, M.D., Ph.D. (2) · Andrew J Buckler (1) · Haruhiko Banno, MD, PhD (1) · Haruhisa Inoue, MD, PhD (1) · Haruyuki Takaki, MD (1) · Hidekazu Tomimoto, MD, PhD (1) · Hiroshi Shiku, M.D. (1) · Hiroshi Yamagami, MD, PhD (1) · Koen Nieman, MD PHD (1) · Koichiro Yamakado, MD (1) · Mineo Kondo (1) · Mineo Kondo, MD, PhD (1) · Nobuyuki Sakai, MD, DMSc (1)
PMID 17021318, PMID 17021319, PMID 31934829, PMID 34193504, PMID 34538630, PMID 35768164, PMID 39162632, PMID 39585936