38 completed, 6 unknown, 6 withdrawn, 5 recruiting. 17 Not applicable, 12 Phase 4, 10 Phase 3, 4 Phase 2, 1 Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of Vaccines Against Bundibugyo Virus Disease in Contacts of Cases in the Democratic Republic of the Congo Candidate BDBV vaccine, Active comparator - Ebola Hemorrhagic Fever, Bundibugyo Virus Disease | Phase 2 / Phase 3 | Not yet recruiting | Jean-Pierre Van geertruyden | 3620 | 2026-10-20 | 2026-10-05 |
| A Study to Evaluate Performance, Usability, and Contrived Result Interpretation of TruPlex HIV/HepB/Syphilis Rapid Test TruPlex HIV/HepB/Syphilis Rapid Test - HIV 1 Infection, HIV 2 Infection | Not applicable | Recruiting | bioLytical Laboratories | 1000 | 2025-12-18 | 2026-10-02 |
| A Study to Evaluate the Performance, Usability, and Contrived Result Interpretation of iStatis Gonorrhea Antigen Test iStatis Gonorrhea Antigen Test - Gonorrhea Infection | Not applicable | Recruiting | bioLytical Laboratories | 650 | 2025-11-26 | 2026-09-30 |
| Clinical Diagnostic Performance Evaluation of a Measles Rapid Test in Senegal Measles rapid diagnostic test - Measles | Terminated | Institut Pasteur de Dakar | 254 | 2025-08-22 | 2026-09-02 | |
| Comparison of Two Strategies for Administering the R21-Matrix M Vaccine in a Context of Seasonal Malaria Transmission in Chad "Synchronised" arm (intervention) - Malaria Infection, Malaria Vaccines | Phase 4 | Recruiting | Epicentre | 70000 | 2025-06-16 | 2026-04-15 |
| Integrating Malaria Vaccine With Seasonal Malaria Chemoprevention in West Africa Annual campaign of the 3-dose primary series vaccine R21/Matrix-M aligned with SMC distribution in children aged 3-59 months - Malaria Vaccine | Phase 4 | Recruiting | Epicentre | 40000 | 2025-06-10 | 2025-08-08 |
| High Flow Nasal Oxygen Therapy an Implementation Study in Pediatric Wards Moderate Respiratory Distress, Severe Respiratory Distress | Not yet recruiting | Epicentre | 960 | 2025-01-01 | 2025-01-30 | |
| Effectiveness of a Microbiome-directed Food to Promote Programmatic and Sustained Nutritional Recovery Among Children With Uncomplicated Acute Malnutrition MDF, RUTF, RUSF - Malnutrition, Child | Not applicable | Unknown | Epicentre | 7356 | 2024-05-02 | 2024-08-27 |
| Solidarity/Tokomeza Ebola Trial CAd3, ChAdox1, rVSV-SUDV - Sudan Ebola Virus Vaccines | Phase 1 / Phase 2 | Not yet recruiting | Makerere University | 2121 | 2023-07-01 | 2023-06-18 |
| Acceptability of a Microbiome-directed Food in Young Children With Acute Malnutrition MDF then RUTF/RUSF, RUTF/RUSF then MDF - Malnutrition, Child | Not applicable | Completed | Epicentre | 274 | 2022-10-26 | 2024-04-17 |
| Development, Feasibility and Acceptability of Recipes for Locally Available, Specially Formulated Foods for the Management of Moderate Acute Malnutrition in Niger (Related to NCT06382857 Protocol) Locally Available Food - Moderate Acute Malnutrition (MAM) | Not applicable | Completed | Epicentre | 30 | 2022-08-19 | 2026-04-07 |
| Immune Response to a Delayed Second Dose of Oral Cholera Vaccine Delayed second dose of oral cholera vaccine, Euvichol-Plus, Oral cholera vaccine, Euvichol-Plus, according to manufacturer notice - Cholera, Vibrio Cholerae Infection | Phase 4 | Unknown | Epicentre | 456 | 2022-07-20 | 2023-03-07 |
| Incidence of Relapse and Post-Kala-Azar Dermal Leishmaniasis in South Sudan Leishmaniasis, Leishmaniasis, Visceral | Completed | Epicentre | 52 | 2022-05-31 | 2025-04-24 | |
| Mass Campaigns With Fractional Dose Pneumococcal Vaccines in Sub-Saharan Africa (fPCV) PCV10 full dose, PCV10 fractional dose - Pneumococcal Carriage | Phase 4 | Completed | Epicentre | 44618 | 2021-12-30 | 2024-12-05 |
| Evaluation of Vaccination Coverage and Determinants of Success of the COVID-19 Vaccination Program Among Populations in Very Precarious Situations Vaccination coverage - COVID-19 | Completed | Epicentre | 3811 | 2021-11-15 | 2023-04-06 | |
| Impact Study of Cholera Vaccination in Endemic Areas - Seroprevalence Cholera | Completed | Epicentre | 7000 | 2021-09-20 | 2024-09-19 | |
| Diagnostic Performance of a Novel Lipoarabinomannan. FUJILAM KIT - HIV Primary Infection | Not applicable | Unknown | Médecins Sans Frontières, Kenya | 550 | 2021-09-01 | 2021-09-08 |
| Level of Immunity, Neutralization of the COVID-19 Virus and Reinfections in Residents of 2 Migrant Workers' Residences Blood and Saliva collection - SARS-COV-2 | Withdrawn | Epicentre | 2021-06-14 | 2021-06-21 | ||
| Impact Study of Cholera Vaccination in Endemic Areas - Clinical Surveillance Cholera | Recruiting | Epicentre | 6000 | 2021-05-11 | 2024-09-19 | |
| Evaluation of Additional Treatments for COVID-19: a Randomized Trial in Niger Lopinavir-Ritonavir Drug Combination, Standard Care - Covid-19 | Phase 3 | Withdrawn | Epicentre | 2020-06-01 | 2021-02-10 |
Showing 20 of 61. Sign in to see all of them.
Malaria (10) · Tuberculosis (8) · Severe Acute Malnutrition (7) · Malnutrition (5) · Tuberculosis, Multidrug-Resistant (5) · Malaria, Falciparum (4) · COVID-19 (3) · Cholera (3) · Hemorrhagic Fever, Ebola (3) · Meningitis, Meningococcal (3) · Trypanosomiasis, African (3) · Bacterial Infections (2) · Child Nutrition Disorders (2) · Tuberculosis, Pulmonary (2) · Acquired Immunodeficiency Syndrome (1)
Artemether, Lumefantrine Drug Combination (3) · Eflornithine (3) · Ciprofloxacin (2) · Clofazimine (2) · Linezolid (2) · Nifurtimox (2) · OPC-67683 (2) · amodiaquine, artesunate drug combination (2) · bedaquiline (2) · lactitol (2) · Air (1) · Amoxicillin (1) · Blood Specimen Collection (1) · Bupivacaine (1) · Cholera Vaccines (1)
Niger (13) · Uganda (13) · Democratic Republic of the Congo (8) · South Africa (5) · Kazakhstan (4) · Lesotho (4) · Pakistan (4) · Peru (4) · Chad (2) · France (2) · Georgia (2) · India (2) · Kenya (2) · Mali (2) · Nigeria (2)
Francesco Grandesso, MSc (3) · Rebecca Grais, PhD (3) · Sheila Isanaka, ScD (3) · Carole Mitnick, Sc.D (2) · Gerardo Priotto, MD, MPH (2) · Lorenzo Guglielmetti, MD (2) · Philippe J Guerin, MD, MPH, PhD (2) · Rebecca F Grais (2) · Rebecca F Grais, PhD (2) · Aitana Juan Giner, MSc (1) · Anne-Laure Page, PhD (1) · Boris Tchounga, MD, PHD (1)
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